Sorex fumeus (smoky shrew): 130040730
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Entry
130040730 CDS
T10594
Symbol
VAV2
Name
(RefSeq) guanine nucleotide exchange factor VAV2 isoform X1
KO
K05730
guanine nucleotide exchange factor VAV
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum04015
Rap1 signaling pathway
sfum04024
cAMP signaling pathway
sfum04062
Chemokine signaling pathway
sfum04510
Focal adhesion
sfum04650
Natural killer cell mediated cytotoxicity
sfum04660
T cell receptor signaling pathway
sfum04662
B cell receptor signaling pathway
sfum04664
Fc epsilon RI signaling pathway
sfum04666
Fc gamma R-mediated phagocytosis
sfum04670
Leukocyte transendothelial migration
sfum04810
Regulation of actin cytoskeleton
sfum05135
Yersinia infection
sfum05205
Proteoglycans in cancer
sfum05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
130040730 (VAV2)
04024 cAMP signaling pathway
130040730 (VAV2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
130040730 (VAV2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
130040730 (VAV2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
130040730 (VAV2)
04660 T cell receptor signaling pathway
130040730 (VAV2)
04662 B cell receptor signaling pathway
130040730 (VAV2)
04664 Fc epsilon RI signaling pathway
130040730 (VAV2)
04666 Fc gamma R-mediated phagocytosis
130040730 (VAV2)
04670 Leukocyte transendothelial migration
130040730 (VAV2)
04062 Chemokine signaling pathway
130040730 (VAV2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
130040730 (VAV2)
09171 Infectious disease: bacterial
05135 Yersinia infection
130040730 (VAV2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
130040730 (VAV2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RhoGEF
CAMSAP_CH
CH
SH2
PH
SOS1_NGEF_PH
C1_1
SH3_2
SH3_1
DUF7145
RHG20_PH
SH3_9
C1_2
PH_10
PH_16
Motif
Other DBs
NCBI-GeneID:
130040730
NCBI-ProteinID:
XP_055988698
LinkDB
All DBs
Position
Unknown
AA seq
892 aa
AA seq
DB search
MEQWRQCGRWLVDCRVLPHDHRVLWPSAAVFDLAQALRDGVLLCQLLHQLCPGSVDPKDI
NFRPQMSQFLCLKNIRTFLRVGHDVFGLRSSDLFDPFDLFDVRDFGKVISALSRLSHHSI
AQSKGIRPFPSEDTVENDDDIYRSLEELADEHDLGEDIYDCVPCEDEGDDVYEDIIRVEV
QPPMKMGMSRDDKRSRCLLEIQETEAKYCRTLEDIEKSYVGPLRPLLSPADMAAIFINLE
DLMKVHQSFLRAIDVAMLAGGGSLATVFLDFKERLLIYGDYCSRMEHAQNTLNQLLATRD
DVRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSTDRPDRQQLKEALEA
MQDLAMYINEVKRDKETLKKVAEFQSCIENLQVKLEEFGRPKIDGELKVRSMVNHTKQDR
YLFLFDKVVIVCKRRGYSYELKEIIELLAHKVSDDPMNNKDIKKWSYGFYLIHLQGKQGF
QLFCKTEDMKRKWMEQFEMAMSNVKPDKAGANQHAFQMFTFARTTTCRACRMLLRGTFYQ
GYLCARCGVGAHKECLEVTPPCKTGSPADVDTPGAGPGPKMVAVQSYHGSPAPPGKPVLT
FQTGDIIELLKGDPESPWWEGRLVLTRKSGCFPSASVKPCPADGRPPVSRPPSRELDYTM
YPWFAGSMERQQTDTLLKPHASGTYLIRERPAEAERFAISVKFNDEVKHIKVVEKDGWIH
ITEAKKFESLLELVEYYQCHSLKESFKQLDTTLKHPYKSRERLASRASSRSPVLRASASL
LRAPPPRSGQVSLRASRRRHGRGQVQLRRPGHAGALAAGGGRGEDLQPRRRGPGLVEGRD
PRPDRLVPFDVRGGGGRPVTRESGQDILGKLQLWSRSGSRTPGAVPASICLP
NT seq
2679 nt
NT seq
+upstream
nt +downstream
nt
atggagcagtggcggcagtgcggccgctggctggtggactgccgcgtcctgccgcacgac
caccgcgtgctctggccctcggccgccgtcttcgacctggcgcaggcgctgcgcgacggc
gtgctgctgtgccagctgctgcaccagctctgccccggctccgtggaccccaaggacatc
aacttccggccgcagatgtcgcagttcctgtgtctgaagaacatccgcaccttcctccgg
gtgggccatgacgtgtttggactccgcagctctgacctcttcgacccctttgacctcttc
gatgtccgggacttcgggaaggtcatctcggccctgtcgagactttcccatcacagcatc
gcgcagagcaaaggaatcaggcctttcccctcggaggacacggtggagaatgacgatgac
atctaccgcagcctggaggagctggccgacgagcatgacctgggcgaggacatctacgac
tgcgtcccttgcgaggacgagggcgacgacgtgtacgaggacatcatcagggtggaggtg
cagccgcccatgaaaatgggcatgagccgggacgacaagcgcagccgctgcctgctggag
atccaggagaccgaggccaagtactgccgcacgctggaggacatcgagaagagctacgtg
ggccccctcaggccgctgctgagccccgcggacatggccgccatcttcatcaacctggag
gacctgatgaaggtgcaccagagcttcctgagggccatcgatgtggccatgctggcgggc
ggcggctccctggccaccgtcttcctggacttcaaggagcggctcctgatctacggagac
tactgcagccgcatggagcatgcccagaacacgctcaaccagctgttggccacccgtgac
gacgtgaggcagaaggtcgaggagtgcacgctgaaggtccaggacgggaagttcaagctg
caggacctgctggtggtgcccatgcagagggtgctcaagtaccacctgctactcaaggaa
ctcctgagtcactccacggaccggccggacaggcagcagctcaaggaagctttagaagct
atgcaggacctggccatgtacataaacgaggtgaagagggacaaggagactctgaagaaa
gtggccgagttccagagctgcatcgagaacctgcaggtgaagctggaggagttcgggcgg
ccgaagattgacggggagctgaaggtgcgctccatggtcaaccacaccaagcaggacagg
tacttgttcctgtttgacaaggtggtgatcgtgtgcaagcggcggggctacagctacgag
ctgaaggagatcatcgagctgctggcccacaaggtgtcggacgaccccatgaacaacaag
gacatcaagaagtggtcctacggcttctacctcatccacctgcaaggcaagcagggcttc
cagctcttctgcaagaccgaggacatgaagcgcaagtggatggagcagttcgagatggcc
atgtccaatgtgaagcccgacaaggccggtgccaaccagcatgccttccagatgttcaca
ttcgccaggaccaccacgtgccgcgcctgccgcatgctgctcaggggcactttctaccag
gggtacctgtgcgcccggtgcggtgtcggtgcgcacaaggagtgtctggaggtgacaccg
ccctgcaagacaggttcccctgcagacgtggacacccccggagcgggaccaggtcccaag
atggtggctgtgcagagttaccacggcagccccgcgccccccgggaagccggtgctcacc
ttccagacgggcgacatcatcgagctgctcaagggcgaccccgagtccccgtggtgggag
ggccggctggtgctgacccgcaagtctggctgcttccccagcgcgtctgtgaagccatgt
cccgcggacgggcggccgcctgtttcccggccaccctcccgtgagcttgactacaccatg
tacccctggttcgctggcagcatggagaggcaacagactgacaccctgctgaagccccac
gccagcggcacctacctcatccgggagcggccggctgaggccgagcgcttcgccatcagc
gtcaagttcaacgacgaggtgaagcacatcaaggtggtggagaaggacggctggatccac
atcaccgaggccaagaagttcgagagcctcctggagctggtggagtactaccagtgccac
tcgctcaaggagagcttcaagcagctggacacgaccctcaagcacccctacaagtcccgg
gagcgcttggcctctagggcctccagccggtccccagtcctcagggcctcagcctcgctg
ctcagggctcctccgccccgttctggtcaggtcagtcttcgcgcctcgcgtcgtcggcac
ggccgtggccaggtacaacttcgccgcccgggacatgcgggagctctcgctgcgggaggg
ggacgtggtgaagatctacagccgcgtcggcggggaccggggctggtggaagggcgagac
ccacggccggatcggctggttcccttcgacgtacgtggaggaggagggcgtccagtgacg
cgggagtctggacaggacattcttgggaagctgcagctctggtctcgctctggctccagg
actccgggggccgtgcccgccagcatctgtctcccctag
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