Sorex fumeus (smoky shrew): 130041149
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Entry
130041149 CDS
T10594
Symbol
HIF1A
Name
(RefSeq) hypoxia-inducible factor 1-alpha isoform X1
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum04066
HIF-1 signaling pathway
sfum04137
Mitophagy - animal
sfum04140
Autophagy - animal
sfum04148
Efferocytosis
sfum04659
Th17 cell differentiation
sfum04919
Thyroid hormone signaling pathway
sfum05167
Kaposi sarcoma-associated herpesvirus infection
sfum05200
Pathways in cancer
sfum05205
Proteoglycans in cancer
sfum05208
Chemical carcinogenesis - reactive oxygen species
sfum05211
Renal cell carcinoma
sfum05230
Central carbon metabolism in cancer
sfum05231
Choline metabolism in cancer
sfum05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
130041149 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
130041149 (HIF1A)
04137 Mitophagy - animal
130041149 (HIF1A)
04148 Efferocytosis
130041149 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
130041149 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
130041149 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
130041149 (HIF1A)
05205 Proteoglycans in cancer
130041149 (HIF1A)
05208 Chemical carcinogenesis - reactive oxygen species
130041149 (HIF1A)
05230 Central carbon metabolism in cancer
130041149 (HIF1A)
05231 Choline metabolism in cancer
130041149 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
130041149 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
130041149 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
130041149 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
sfum03000
]
130041149 (HIF1A)
Transcription factors [BR:
sfum03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
130041149 (HIF1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
DDRGK
Motif
Other DBs
NCBI-GeneID:
130041149
NCBI-ProteinID:
XP_055989159
LinkDB
All DBs
Position
Unknown
AA seq
826 aa
AA seq
DB search
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVKKGKEQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNNNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECI
LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTDT
DDQQLEEAPLYNDVMLPSSSEKIQNINLALSPLPASETPKPLRSNADPALNQEVALKLEP
NTESLELSFTMPQIQDQPVSPSDGSTRQSSPEPTSPSGYCFDVDSDMVNEFKLELVEKLF
AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSSSPQNASTITVFQ
PPTPMQESTISTATATTDELKAVTKDGMEDIKVLIASPSPTHISKETTSATTSPYSDTRS
RTASPNRAGNGVIEQTEKSHPRSPNVLSVTLSQRNTVPEEELNPKIIALQNAQRKRKIEH
DGSLFQAVGIVSLKGTLIQQPDNRTTTSSLSWKRVKGCKTSEQNGMEQKTIILIPSDLAC
RLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2481 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgcgggcggcgcgaacgacaagaaaaagataagttctgaacgccgaaaagaa
aagtctagagatgctgcccgatctcgtcggagtaaagaatctgaagttttttatgaactt
gctcatcagttgccacttccccataatgtgagctcgcaccttgataaagcttctgttatg
agacttaccattagctatttacgtgtgaggaaacttctggatgctggtgatttggatatt
gaagatgaaatgaaggcacagatgaattgtttttatctgaaagctttggatggttttgtt
atggttctcacagatgatggcgacatgatttacatttctgataatgtgaacaaatatatg
ggattaactcagtttgaactgactggacacagtgtatttgactttactcatccatgtgac
catgaggaaatgagagaaatgcttacacacagaaatggccccgtgaaaaagggtaaagaa
caaaatacacaaagaagcttttttttgagaatgaagtgtaccctaactagccggggaaga
actatgaacataaaatctgcaacatggaaggtacttcattgcacaggccatattcatgtg
tacgataccaacaataatcagtctcagtgtgggtataagaaaccacctatgacgtgcttg
gtgctgatttgtgaacccattcctcatccatcaaatattgagattcctttagatagtaag
actttcctcagtcgtcacagcctggatatgaaattttcttactgtgatgaaagaattact
gaattgatgggatatgagccagaagaacttctgggccgctcaatatatgaatattatcat
gctttggactctgatcatttaaccaaaactcatcatgatatgtttactaaaggacaagtt
accacaggacagtacaggatgcttgcaaaaagaggtggttatgtatgggttgaaactcaa
gcaactgtcatatataacaccaagaattctcaaccacaatgcattgtgtgtgtaaattat
gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtatc
ctcaaaccagttgaatcttcagatatgaaaatgactcagctattcaccaaagttgaatcc
gaagacacaagtagcctctttgacaaacttaagaaggaacccgatgctttaactttgctg
gcacctgctgctggagacacaatcatatctttagattttggcagcaatgatacggacact
gatgaccaacaactggaagaagctccattgtacaatgatgtaatgctcccttcatcgagt
gaaaaaatacagaatattaatttggcactgtctccattacctgcttctgaaactccaaag
cctcttcgaagtaatgctgaccctgcactcaaccaggaagttgcattaaaattggaacca
aatactgagtcgctagaactttcttttacaatgccccagattcaagatcagccagtcagt
ccttctgatggaagcactagacaaagttcacctgagcctaccagtcccagcggatactgt
tttgatgtggatagtgacatggtcaatgaattcaagttggaattggtggagaaacttttt
gctgaagacacagaagcaaagaatccattttccactcaggatactgatttagacttggag
atgttagctccctatatccctatggacgatgacttccagttacgttccttcgatcagttg
tcaccattggagagcagttcttcaagccctcaaaatgcaagcacaattacagtattccaa
ccaccaactccaatgcaagaatctactatttccactgccactgccaccactgatgagtta
aaagcagtgacaaaagatggtatggaagacattaaagtattgattgcatctccatctcct
actcatatatctaaagaaactacaagtgccacaacgtcaccctatagtgatactcgaagt
cgaacagcttcaccaaacagagcaggcaatggagtcatagaacagacagaaaaatctcat
ccaagaagccctaatgtgttatctgtcactttgagtcaaagaaacactgttcctgaggaa
gaactaaatccaaagataatagctttgcaaaatgctcagagaaagcgaaaaatagaacat
gatggttcactttttcaagcagtaggaattgtaagtctgaaaggaacattaatacagcaa
ccagataaccgcacaactacttcatcgctttcctggaaacgagttaaaggatgcaaaacc
agtgaacaaaatggaatggagcagaagacaattattttaataccctctgatttagcatgt
cgattgctggggcaatcaatggatgaaagtggattgccacaactaacgagttatgattgt
gaagttaatgctcctatacaaggcagcagaaatctactgcagggtgaagaattactcaga
gctttggatcaagttaactga
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