Sorex fumeus (smoky shrew): 130041792 Help Entry 130041792         CDS       T10594                                  Symbol SPG11 Name (RefSeq) spatacsin   KO K19026   spatacsin Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum05014   Amyotrophic lateral sclerosis sfum05022   Pathways of neurodegeneration - multiple diseases Brite DNA repair and recombination proteins [BR:sfum03400]  Eukaryotic type   DSBR (double strand breaks repair)    HR (homologous recombination)     Other HR factors      130041792 (SPG11) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spatacsin_C Motif Other DBs NCBI-GeneID:  130041792 NCBI-ProteinID:  XP_055990031 LinkDB All DBs Position Unknown AA seq 2444 aa AA seqDB search MAAEKGAGSASASGGCGSGDMERVLPMLLVPTPSEATRRLGSRAQLHRDQEVLGSLTAVG SLQVLSLAPGDPGGGGGCCLDGPFRHFVWEDSHNSGTPVDKPRLLALTENYELIIYEFNL KDGRCDVTISYSCNEETLQKLIEEQHISTSLLSLRILSFHDNMSLLFINKCIILHLIFPE RDAEIRVFNCFTLPLPAPSVDRIIDTQLCRGILFVLSSLGWIYIFDIVDGTHVAHVDLTL HQEDMCDEEHHEPARISSFTSLKVSQDLDVAVIISSSNSAIAVNLSLYFRQHPGHLLYER TLEDLPVEGPKGIDEDDPANSYYNMKLTKFSFQVDRSWKAQLSSLDERVKNSKLEISHCA PWFQGLLRSDSPESVTHSTSMPLWDFILQDIMYNPCNFPQKDHDKNGDPGKSWKIMHISE KDPIKLKCLSVTRFTALFTWSVEGTGCTIVLWDLETQAMQHFSYHKMCIPVDSSGDQQLC FVLTENGLSLILFGLTQEEFLNRLMIHGNASTVDSLCHLNGWGRCSIPIHALEAGIENRQ LDTVDFFLKSKENLLNPSSKSSVLDQFNHFPSHLYLRNVEELTPALDLLCSSIRESDSET QSKHFSEQLLNLTLSFLNKQIRELFVHNKELDEQLQKGVDILSKYINELRTFMIKFPWKL TDAINEYDIKEDVLTVKESSMWEKLSTEEVIANAILNNKIPEAQTFFRIRNHSAQKLEEL IRIGLDLVFDNLKNSNIKEASELLKNMGFDVKDQLLRICFYTTDKSIRNFLVEILKEKNY FSEKDERTIDIVHQVEKLYSGHYQENAQIQSFPRFWRKKQDFFKHKCTLDSFLKYDQKDK FKNQDHRIVINWAQWWNQLTQESVLLPKISLEEYKSYSPEALWRYLTVRHDWLNIILWIE EFLTQKNSISLQQNKWPSLTIDVIDQNTCCNKYMKNEILNKLARNGIFLTSELQDFELFL LRLNCVGGVMQDSLPIQNYRSKEGWDFHSLFILYCLEHSLQYLLYVYLDYYKLSPSNCSF LEKKELHEAYPWFEFLVQCRQVSSHLKDPKLIFQASLANAQILIPSNQASISSMLLEGHT LLALATTMYGPGGVSQVVQNEENENSLKKVDPQLLKVALTPYPKLKTALFPQYIAPSILP PDITLYHLIQSLLPFDPSRLFGWQSTNTLAIGDAASHLPHFSSPDLVNKYAIMERLNFAY YLHRGRPSFAFGTFLVQELAKSKTPKQLIQQVGTEAYVLGLSSFYTPSIGAACVCFLELL GLDSLKLRVDMKVANTILSYKCKNEDAQYSFIRESLAEKLSKLAAGEKATTEELLVFLEE SIWNSIQQQEIKRLSSDSSSQWALVVQFCRLHNMKLSMSYLKECAKANDWLQFIIHSQLY NYHPEEVKVLLHYFSPVLQDHLKLAFENLPPESNSRMDSDPVCTKSPHTFQRSKEETTGL FEILLQCSEEPDSWCWLLAEAVRQQAPVLSVLASCLQDASSIPCVCVWIITSLEDSVAAE AVGHIQSSVEGHTWDLKDLSIIWRTLLTRQKSKTLIRGFQLFFKDSPLLLMMEMYELGMF FKNYKAAEAKLLEFQKILETPETTAPRANVLPAPWLKEQVHFLLKLMLQQCRTQYELGKL LQLFVGIEHLFFDGPDIKKLYNLSQILKETSIAINHVIINSYSLENFQHECRSIMEKLET DGEFVLARKVAELAELPVDHLVVEEITREMQTLKHVEQWCLKQARIDFWKKCHENFKKNS ISNRAASSFFSAQALATCECPATTGQSSTEERHLLLTLAGHWLAQEDLVPVEELEELEKQ IWLCRITQHTRGENAEEREPRFARQISTSGELSFDSLASEFSFSKLTALNTSKYLELNGL PSRETCENSLNRKELESLNFLIGRLLDDGCVHEASRVCRYFNFYSQDVALVLHCRALASG EASMEDLHPEFQALLQCSELPEEEEPSIPLRKVQSTSSLESESFVMLPSPNEVVTTLETL TVKCLHGKNYCRQVLCLYELAKELGCSYADVAARDGEAMLRAILVSQRPDRCKQAQAFIS TQGLEPDTVAELVAEEVTQELLTSSEGTGHKHVFTPAEESQMFLQLTTLCQDRTLLGMKL LDKISSVPHGELACTTELLILAHHCFTLTCHMEGIIRVLQAARLLTDNHLAPNEEYGLVV RLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKHNM IALCFSMCREIGENHEAAARIQLKLIESQPWEDSLKDGPQLKQLLLKALTLMLDAAESYA KDSCVRQALHCHRLTKLITLQIHFLNTGQNTMLINLGRHRLTECIMTLPRFYQASIVADA YDFIPDWAEILYQQVILKGDFNYLEEFKQQRLLSSNIFEEISKKYKHQPATSDTVMKNLK KLLTYCEDVNLYYKLACENKFYDIVNMLLKDPQTGYYLKDMLAG NT seq 7335 nt NT seq  +upstreamnt  +downstreamnt atggctgccgagaagggggccggaagtgcttccgccagtggcggctgtggctcaggagac atggagcgagttctacctatgttgctggtgccgaccccctccgaggcaacgaggcggctg ggatctcgggcgcaactgcaccgagaccaggaggttctgggaagcctgactgccgtaggt agccttcaagtgctttccttggcgccgggcgaccccggaggaggaggcggctgctgcctc gacggcccatttcggcactttgtttgggaggattctcataatagtggcacaccagtagac aaacccagactgcttgctcttactgaaaattatgaactgatcatctatgaatttaattta aaagatggaagatgtgatgtaaccatttcgtatagctgtaatgaggagacattgcaaaaa ctcattgaagagcaacatatcagtacttccttattatctttgagaattttgtcatttcat gataacatgtcgttattgttcatcaacaaatgcatcattctacatcttatattccctgaa agagatgctgaaattagagtattcaactgtttcacattgcctttgcctgcaccgtcagtg gacaggattattgacacgcagctctgcagaggaattctttttgttttgagtagtttaggt tggatctacatttttgacattgtggatggtacacatgtagctcatgtggatctaacactt caccaagaagatatgtgtgatgaagagcaccatgagccagccaggatttcttcttttact tcactgaaagtgtctcaagacctagatgttgcagtgattatcagctcctccaactctgca attgctgttaatttaagtttgtatttcaggcaacacccaggacaccttctgtatgaaaga actctagaagaccttcctgttgaaggaccaaagggcattgatgaagatgatcctgctaac tcctactacaacatgaaactgacaaaattctccttccaagttgataggtcttggaaagcc cagctgtcatcgttggatgaaagagtaaaaaactctaaactggagatttcccactgtgct ccttggttccaaggtttattgcgttcggattccccggaatctgttactcatagcaccagt atgccgctctgggacttcatattacaagacataatgtacaatccatgtaattttccacag aaagatcatgacaagaatggtgatccaggaaaatcatggaagataatgcacattagtgag aaggatcctatcaagcttaaatgtttgtctgtgacaaggttcactgctctctttacttgg tcagtggaagggactggctgcaccattgtcctttgggatttggagacccaggccatgcag catttttcctatcacaaaatgtgtattcctgtagacagtagtggagaccagcaactatgc tttgttttgacagaaaatggactctctctgattttgtttggtttgactcaagaggagttt ttaaatagactaatgatccatggaaatgccagcactgtggattcgctctgccatctcaat ggttgggggaggtgctcaatccccatacatgcattagaggctggaatagaaaatcgtcaa ctggacacagtagatttctttttgaagagcaaggaaaatcttttaaatccatcttcaaaa tcttctgtacttgaccagtttaatcactttccatcccacctatatttaagaaatgttgaa gagttgaccccagcattggatttactgtgctcatcaattagagaaagtgattctgaaacc cagagcaaacacttttcagaacaattgcttaatcttacactgtcttttcttaataaacaa ataagagaactttttgttcataataaagagttagatgaacagctacagaaaggagtggac attctatccaaatacattaatgaacttcggacctttatgataaagtttccttggaagcta acagatgctataaatgaatatgatataaaagaagatgtcttgacagtaaaggagagcagt atgtgggagaaactcagcactgaggaagttattgccaatgccattttaaacaataaaata ccagaggcacaaacattcttccggattagaaaccattctgctcaaaaacttgaggaactg attagaataggcctagatttggtctttgacaatttaaagaacagcaatataaaggaagcc tctgaacttttgaagaatatgggctttgatgtaaaagaccagttgcttaggatatgcttt tatacaaccgataagagtatacggaactttctggttgaaatcttaaaagaaaaaaattac ttttctgaaaaagatgaaagaactatagacattgtacatcaagttgagaagttatattca ggacattaccaagaaaatgcgcagatccagtcctttcccaggttttggagaaagaaacaa gactttttcaagcacaaatgtactttggactcattcctgaagtatgatcagaaagataaa tttaaaaatcaggatcatagaattgtgataaattgggcacagtggtggaatcaattgaca caagagtctgtccttctccccaagataagtctagaagagtacaaatcatattcccctgaa gccctctggagatacctaacagttcgtcatgattggttaaatattatcttgtggattgaa gaatttctgacccagaagaattccatctcactccagcagaacaaatggccctctctgacc attgatgttattgatcagaatacttgctgtaacaaatatatgaagaatgaaattttgaat aagctggctaggaatggaatttttcttacatctgaactacaagactttgaactcttcctt ctaagactgaattgtgttgggggtgtgatgcaagactctcttcctattcaaaactacagg tccaaggaaggttgggatttccattctctcttcattctctattgtttggagcacagtttg cagtatctgctctatgtctatcttgactattacaaacttagtccatccaattgttccttt ttggaaaaaaaagaattacatgaagcttacccttggtttgaatttttagttcagtgtcga caagtttccagtcatttaaaagatccaaaattgattttccaggctagtcttgcaaatgct cagatactgattcctagcaatcaggctagtataagcagcatgctattggaaggacatacc ctcctggcacttgctaccacaatgtatggccctgggggtgtcagccaggttgttcagaat gaagaaaatgagaacagtttgaagaaagtggacccccagctactgaaggtggcattaact ccttatcccaagttaaaaactgctctctttccacagtacattgcccctagtatcctgcca ccagatatcacactctatcacctcattcagtcactgttgccctttgatcctagcagattg tttggctggcaatctaccaacacactcgcaataggagatgcagcaagtcatctcccacat ttttctagccctgacctggttaataaatatgctataatggaacgtctgaattttgcttat tatttgcatcgcggacggccatcatttgcatttggtacttttcttgtccaggagttagct aagagcaagactcccaagcaactgatccagcaagtaggtactgaagcttatgttttagga ctgtcctccttctacacaccttcaataggagctgcctgtgtttgtttcttagaattactt ggtcttgacagcctcaagcttcgagttgatatgaaagtggccaatacaattttgagctac aagtgtaaaaatgaagatgctcaatacagctttatcagagaatctctagctgaaaaactg tctaaactggctgcaggtgaaaaggcaaccacagaagaattgcttgttttcttagaagaa agtatatggaatagcattcagcaacaggaaataaagagattatccagtgactctagcagc cagtgggcattggtggtacagttctgcaggctccacaatatgaaactgagcatgtcttac ctgaaggaatgtgcaaaagcaaatgattggttacagttcattattcatagccaactctat aattaccatccagaagaggtgaaagttcttcttcattattttagccctgttcttcaagac cacttgaagttggcttttgagaacttgcccccagagtcaaactccagaatggacagtgat ccagtctgcaccaagtctcctcacactttccagagaagcaaagaagagacaactggtctc tttgaaattctgcttcagtgttcagaggagccagattcctggtgttggctcctggctgaa gcagtgagacaacaggcccctgtccttagtgtcctggcctcctgtctccaggatgccagt tccattccttgtgtctgtgtttggatcatcacttctctggaagacagtgttgcagctgaa gcagtaggccatattcagagctcagtggaaggccacacctgggacctaaaggacctttcc attatctggagaacattattgacaagacagaagagcaaaactctcatcagaggtttccag ttgttctttaaggattccccactgctattgatgatggagatgtatgaacttggtatgttc tttaagaattataaggcagcagaagcaaaacttctggagttccaaaagatcctggaaact cctgaaacaacagccccaagggccaatgttctccctgctccatggctgaaggagcaggtg catttccttttgaagctcatgctacagcagtgtcggactcagtatgagctagggaagctt ttgcagttgtttgttggaatagagcatctcttcttcgatggtccagatattaaaaagctg tataatcttagccagattttgaaggagacatccattgcaattaatcatgtaattattaac agctacagccttgagaattttcaacatgaatgtagatctattatggaaaaattggagaca gatggagagtttgtcttggccaggaaagtagcagaattagctgagttacctgtggaccac ttggttgttgaagagataactcgggaaatgcagaccttaaagcatgttgagcagtggtgt ctgaaacaagcaagaattgatttctggaaaaaatgccatgagaatttcaagaagaattcc atttcaaacagagcagcttcttcctttttctcagctcaggccctggcaacttgtgagtgc ccagccaccacggggcagagcagtactgaggagcgccacctgctgctcaccttggcaggg cactggcttgcccaggaggacttggtgccagtggaggagctggaggagctggagaagcag atctggctctgccggattacccagcacacccgtggagaaaatgccgaggaaagagagccc aggtttgctcgacagatttcaactagtggtgaactttcttttgacagcttagccagcgaa ttttcattctccaaattgactgctctgaacacatctaaatatttagaacttaatggcctt ccatccagagagacttgtgagaatagcctaaataggaaagagctggagtcgctaaacttt ctgattgggcgcctattggatgatggctgtgtgcatgaagcaagtagagtgtgccgttat tttaatttctatagccaagatgttgcactggtgttgcactgcagagctctagcttcaggg gaagctagtatggaagacctccatccagagttccaggctctcctgcagtgttctgagctg cctgaagaggaagaacctagcattcctctacggaaagtccagagcacctcaagcttggag agcgagtcatttgtgatgctgccctcccccaatgaagttgtgaccaccctggaaaccctg actgtcaaatgcttgcatgggaagaactactgccggcaggttctctgtctctacgaactt gccaaggagctgggctgttcctacgctgatgttgctgcccgggatggggaggccatgctc cgggcaatcctggtctctcagcggcccgacagatgcaagcaagcccaggcattcatcagc actcagggccttgagccagacacagtggctgaacttgtggccgaagaggtgacacaggag ctgctaacctcatctgagggcacaggacacaaacatgtgttcaccccggcagaggagagc cagatgtttcttcagctcaccactctgtgtcaagatcgcacattgctaggcatgaagttg ctggataagatttcttctgttcctcatggggaactggcttgcaccacggagctgctgatc ctggcccaccactgcttcacactgacctgccacatggagggcatcatccgagtcctgcag gctgcccggctgctcactgacaaccatttggcccccaatgaggagtacggacttgtggtg cgtctcctgactggtattggaaggtacaacgagatgacatatatatttgatttgctccat aaaaagcactactttgaagtgctaatgaggaagaaattggatccgagtggtaccctgaag acagctctgcttgactacatcaaacgctgccgccctggggacagcgagaagcacaatatg atcgccctgtgcttcagcatgtgtcgggagataggggagaaccatgaggcagctgcccgc atccaactgaaactgatcgagtctcaaccctgggaggacagcctcaaagatggtccccaa ctgaagcagctgctgctgaaggctctgactctgatgctggatgcagcagagagttatgcc aaggactcttgtgtgcgacaggctttgcactgtcaccggcttaccaagctaataacactg caaattcactttttgaacactggccagaacacaatgctcatcaacctgggccgccacaga ctgacagaatgtatcatgacccttccacggttctatcaggcttctattgtggctgatgca tatgacttcattcctgattgggctgaaattctataccaacaagtgattcttaaaggagac ttcaattatttagaagaatttaagcagcaacggttattaagctccaacatatttgaagaa atttcaaagaaatataaacatcagcctgccacctctgacacagttatgaaaaacctgaag aagttactcacatactgtgaagatgtcaatttgtattacaagttggcatgtgaaaacaaa ttttatgacattgtaaatatgcttctgaaggaccctcagacagggtactacctaaaggac atgctagcaggttag

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