KEGG   Sorex fumeus (smoky shrew): 130041925
Entry
130041925         CDS       T10594                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2 isoform X1
  KO
K10140  DNA damage-binding protein 2
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum03420  Nucleotide excision repair
sfum04115  p53 signaling pathway
sfum04120  Ubiquitin mediated proteolysis
sfum05161  Hepatitis B
sfum05169  Epstein-Barr virus infection
sfum05200  Pathways in cancer
sfum05202  Transcriptional misregulation in cancer
sfum05210  Colorectal cancer
sfum05212  Pancreatic cancer
sfum05213  Endometrial cancer
sfum05214  Glioma
sfum05216  Thyroid cancer
sfum05217  Basal cell carcinoma
sfum05218  Melanoma
sfum05220  Chronic myeloid leukemia
sfum05222  Small cell lung cancer
sfum05223  Non-small cell lung cancer
sfum05224  Breast cancer
sfum05225  Hepatocellular carcinoma
sfum05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    130041925 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    130041925 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    130041925 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    130041925 (DDB2)
   05202 Transcriptional misregulation in cancer
    130041925 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    130041925 (DDB2)
   05212 Pancreatic cancer
    130041925 (DDB2)
   05225 Hepatocellular carcinoma
    130041925 (DDB2)
   05226 Gastric cancer
    130041925 (DDB2)
   05214 Glioma
    130041925 (DDB2)
   05216 Thyroid cancer
    130041925 (DDB2)
   05220 Chronic myeloid leukemia
    130041925 (DDB2)
   05217 Basal cell carcinoma
    130041925 (DDB2)
   05218 Melanoma
    130041925 (DDB2)
   05213 Endometrial cancer
    130041925 (DDB2)
   05224 Breast cancer
    130041925 (DDB2)
   05222 Small cell lung cancer
    130041925 (DDB2)
   05223 Non-small cell lung cancer
    130041925 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    130041925 (DDB2)
   05169 Epstein-Barr virus infection
    130041925 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:sfum04121]
    130041925 (DDB2)
   03400 DNA repair and recombination proteins [BR:sfum03400]
    130041925 (DDB2)
Ubiquitin system [BR:sfum04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     130041925 (DDB2)
DNA repair and recombination proteins [BR:sfum03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      130041925 (DDB2)
SSDB
Motif
Pfam: WD40_CDC20-Fz WD40 WD40_Prp19 WD40_WDHD1_1st Beta-prop_WDR75_1st WDR55 Beta-prop_RIG_2nd Beta-prop_EML_2 Beta-prop_EIPR1 Beta-prop_WDR19_1st Beta-prop_IFT140_1st Beta-prop_WDR90_POC16_2nd EIF3I Beta-prop_TEP1_2nd WD40_RFWD3 Beta-prop_TEP1_C Beta-prop_CAF1B_HIR1 Beta-prop_EML Beta-prop_HPS5 NBCH_WD40 PEP5_VPS11_N WD40_MABP1-WDR62_2nd Beta-prop_Vps41
Other DBs
NCBI-GeneID: 130041925
NCBI-ProteinID: XP_055990191
LinkDB
Position
Unknown
AA seq 424 aa
MAPRKRPEKQKTLEVAVRPASKRSRSPREPEPEAKQRRLKSPGSSGKFDSGCLWAGLASL
QVPPLPSNSIIKALQHRKLGQAVQQALQQSFLHSLASYEIFQRAAPFDRRATALAWHPAH
PNILAVGSKGGDIFLWNVRLKNKPTFLKGIGAGGSITGMKFNPLNHNQLFTSSMEGTTRL
QDFKGNTIRVFTSSSSCNVWFCSLDVSARSHVVVTGDNMGNVSLLTTDGKELWNLKMHKK
KVSHVALNPCCDWVLATASVDQTVKIWDLRQVKGKSSFLCSLPHCQGVNSAAFSPDGARL
LTTDQKSELRVYSASRWDCPPNLIPHPHRRFQHLTPIKATWHPRHDLIIVGRYPDPHFTS
CAPSELRTIDVFDGSSGKMLYQFSDPGSLGIISLNEFNPMGDTLASLMGYNILVWSQKEV
GTQE
NT seq 1275 nt   +upstreamnt  +downstreamnt
atggctccccggaaacgccccgaaaagcagaagaccctcgaggtggccgtgcgccccgcg
agcaagaggagccggagcccccgggagccggagcccgaggccaaacagcggcggctgaag
agccccggttccagcgggaagtttgactcaggctgcctttgggcgggcttggcgagcctg
caggtccccccactgccaagcaacagcatcatcaaggcccttcagcaccggaaactgggc
caggctgtgcagcaggctctccaacagtcctttttgcactctctggcttcttacgagata
tttcaaagggctgcaccctttgaccggagggccacagccttggcatggcacccagctcac
cccaacatcctggctgtggggtccaaaggaggagatatctttctctggaatgtccgactg
aagaacaaacccaccttccttaaagggattggcgctggagggagtatcactgggatgaag
tttaaccctctcaaccacaaccagctgttcacctcctccatggagggaacaaccaggctg
caagactttaaaggcaacacgatccgcgtttttaccagctccagctcctgcaacgtctgg
ttttgcagcctggacgtatccgcccgaagccacgtggtggtcacaggggacaacatgggg
aacgtgagcctgctgactacggatggcaaggagctctggaatctgaaaatgcataaaaag
aaagtgtcccacgtggccctgaacccctgctgtgactgggtcctggccacggcctccgtc
gaccagactgtgaaaatctgggacctgcgccaggtgaaagggaagtccagcttcctctgc
tccctgccccattgccagggtgtcaactcagctgctttcagccccgatggcgcccggctc
ctgaccacggatcagaagagtgagctccgggtctactcagcctcccggtgggactgcccc
cctaacctgatcccacaccctcaccgccggttccagcacctcacgcccatcaaggccact
tggcatccccggcacgacctcatcatcgtgggccgataccccgaccctcatttcacaagc
tgtgccccctccgaattacggaccatcgacgtgtttgatggaagctcagggaagatgctg
tatcagttcagtgacccaggatctttgggtatcatctcgctcaatgaattcaatcccatg
ggggacacactggcctctctgatgggttataacattctcgtctggagccagaaggaagtt
gggacacaggaatga

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