Sorex fumeus (smoky shrew): 130041928 Help Entry 130041928         CDS       T10594                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum04020   Calcium signaling pathway sfum04371   Apelin signaling pathway sfum04713   Circadian entrainment sfum04921   Oxytocin signaling pathway sfum04970   Salivary secretion sfum05010   Alzheimer disease sfum05012   Parkinson disease sfum05020   Prion disease sfum05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:sfum00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     130041928 (RYR3)    04020 Calcium signaling pathway     130041928 (RYR3)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     130041928 (RYR3)   09154 Digestive system    04970 Salivary secretion     130041928 (RYR3)   09159 Environmental adaptation    04713 Circadian entrainment     130041928 (RYR3)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     130041928 (RYR3)    05012 Parkinson disease     130041928 (RYR3)    05020 Prion disease     130041928 (RYR3)    05022 Pathways of neurodegeneration - multiple diseases     130041928 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sfum04040]     130041928 (RYR3) Ion channels [BR:sfum04040]  Voltage-gated cation channels   Ryanodine receptor    130041928 (RYR3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_5 Motif Other DBs NCBI-GeneID:  130041928 NCBI-ProteinID:  XP_055990193 LinkDB All DBs Position Unknown AA seq 4875 aa AA seqDB search MAEGGEGGEDEIQFLRTEDEVVLQCIANIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCVCNFVLEQSLSVRALQEMLANTVENGGEGLSDLSEWAAQGGGHRTLLYGHAILLRH SFSGMYLTCLTTSRSQTDKLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLIL VSVSSERYLHLSVSNGNIQVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVVRLFHGHDEC LTIPSTDQNDSQHRRIFYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGH YLALTEDLGLILQDRGKSDTKSTAFSFRASKEIKEKSDSTHKRDIEGMGVPEIKYGDSVC FVQHIASGLWVTYKAQDAKTSRLGPLKRKVILHQEGHMDDGLTLQRCQREESQAARIIRN TTALFSQFISGNNRTAAPVSLPIEEVLQTLQDLIAYFQPPEEEMQHEDKQNKLRSLKNRQ NLFKEEGMLALVLNCIDRLNVYNSVTHFAGIAREESSMAWKEVLSLLYKLLAALIRGNRN NCAQFSNNLDWLISKLDRLESSSGILEVLHCILIESPEALNLIAEGHIKSIISLLDKHGR NHKVLDVLCSLCLCNGVAVRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEG SAQYRKWYFELIIDQVDSFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYG FDGLHLWSGRIPRAVASINQHLLKSDDVVSCCLDLGVPSISFRINGQPVQGMFENFNTDG LFFPVVSFSAGVKVRFLMGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRDAEG VRDLLGTTQFLSQASFIPCPIDTSQVVLPPHLEKIRDRLAENIHELWGMNKIELGWTFGK IRDDNKRQHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEDDLKKVKL PKNYMMANGYKPAPLDLSDVKLLPPQEILVDKLAENAHNVWAKDRIKQGWTYGIQQDLKN KRNPRLVPYALLDERTKKSNRDSLREAVRTFVGYGYNIEPSDQELADPAVEKVSIDKIRF FRVERSYAVRSGKWYFEFEVVTGGDMRVGWARPGCRSDIELGADDQAFVFEGSRGQRWHQ GSGYFGRTWQPGDVVGCMINLEDASMIFTLNGELLITNKGSELAFADYEIENGFVPICSL GLSQIGRMNLGMDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPH IEVVRIDGTMDSPPCLKVTHKTFGTQKSSANMIYCRLSMPVECHSSFSHSPCLDSDTFQK RKQIQEMLSHTTTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLSKNCTVTVTLGD ERGRVHESVKRSNCYMVWGGDVVATSQRSSRSNVDLEIGCLVDLAMGMLSFSANGRELGT CYQVEPNTKVFPAVFLQPTSTSLFQFELGKLKNTMPLSAAIFKSEEKNLVPQCPPRLDVQ TIQPVLWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALYIPEENRCVDILELCEQED LMRFHFHTLRLYSAVCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISI HLANAKERKLMMKNEYIIPITSTTRKIHLYPDGSKRHGLPGVGLRTCLKPGFKFSTPCFV VTSEEHQKQSPEIPLEILKTKALTMLTEAVQCSGAHIRDPVGGSVEFQFVPVLKLIGTLL VMGVFDDDDIRHILLLIDPSVFGEHSGETEEGAEKEEVAQEEEKAVEAGEKASKEAPVKG LLQTRLPESVKLQMCELLSYLCDCELQHRVEAIVAFGDIYVSKLQANQKFRYNELMQALN MSAALTARKTREFRSPPQEQINMLLNFQLGENCPCPDEIREELYDFHEDLLVHCGVPLEE VEEEEEDTSWTGKLRMLMSKVKGPPKLEKKQPREEEEQYPTTLKELISQTMIRWAQEDQI QDAELIRMMFNLLRRQYDSIGELLQALRKTYTISQASVSDTINLLAALGQIRCLLSVRMG KEEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGAEKSQIAFPKMVASC CRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALG LEEPDLEKVVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEEN ASVVVKLLIRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQGYKREISVEDDE DEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGII SIPLKLPSLNKDGSVSEPDMAANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDL RASASLDTVSLSTTEAALALNRYICSAVLPLLTRCAPLFAGTEHFSSLIDSTLQTIYRLS KGRSLTKAQRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLTNHYEQ CWKYYCLPSGWGSYGLAVEEELHLTEKLFWGIFDSLSHKKYDPDLFRMALPCLSAIAGAL PPDYLDTRISATLEKQVSVDAEGNFDPKPINTMNFSLPEKLEYIVTKYAEHSHDKWACDK SQNGWKYGISLDENVRTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAVGWTVERTKEGE ALVQQRENEKLRSMSQASQGNSYSPVPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKL ELESKGGGSHPLLVPYDTLTAKEKFRDREKAQDLFKFLQVNGITVSRGMKDLELDASSME KRFAYKFLKKILKYVDSAQEFIAHLEAIVSSGKTEKSPHDQEIKFFAKVLLPLVDQYFTN HRLYFLSSPLKPLSSSGYASHKEKEMVASLFCKLAALVRHRISLFGSDSTTMVSCLHILA QTLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTLENLKLGKFTHSRTQIKGVSQNINYT TVALLPILTSIFEHVAQHQFGVDLLLGDVQISCYHILGSLYSLGTGKNIYVERQRPALGE CLASLVAAIPVAFLEPTLNRYNPLSVFNTKTPRERSILGMPDTAEEMCPDIPQLDGLMKE INALAESGARYTEMPHVIEVILPMLCNYLSYWWERGPEHQPPSTGPWCTKVTSEHLSVIL GNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAVKTVQEE EQLKADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKSPDADSDQLFR MVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKSGGQDQERKKTKRRGD LYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKSRYSYRDTDEEVKEHLRNNLHLQE KSDDPAVKWQLNLYKDVLKSDEPSNPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKL LSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEEYSFEEKLVQDLAKSPKV DEEKEEEEEMEKQPDPLHQIVLHFSRNALTERSKLEDDPLYTSYSSMMAKSCQSGEDEDE EEDKEKTFEEKEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAIL NGGNAGVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTL IVRERGDKVLQNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVDYLLR LQESISDFYWYYSGKDIIDESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRL WDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMV DTLVESSTNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGIISKKEFQKAMEGQKQYTQ SEIDFLLSCAEADENDMFNYIDFVDQFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLD PAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEG GEQEKMELFVNFCEDTIFEMQLASQISESDSAERPEEQEEEEEDPSYTLEMEGVEVEDTS FESVSAFAMACAAVKKNVANFLKKATLKNLRKQYRKVKKMTVKELVKVFFSFFWMLFVGL FQLFFTILGGIFQVLWSTVFGGGLVEGAKNIRVTKILGDMPDPTQFGIHDDAMEGERAEV TEPGITTELVHFVKGEKGDADLMSDLFGFHQKKEGGVKHGPEVGLGDLSEIIGKDEPPTL ESTVRKKRKAQAAEIKAARDAEGKVDSEKADVEDGEKEDRAKEEEQAETLWAETTKKKKR RRGQKVEKPEAFMANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTE EPLEEESEDVANLWNSFHEDEEEEAMVFFVLQESTGYMAPTLRALAIIHTVISLVCVVGY YCLKVPLVVFKREKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVK RKVINKYGDLYGAERIAELLGLDKNALDFSPVEETKAEAASLVSWLSSIDMKYHIWKLGV VFTDNSFLYLAWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVG LLAVVVYLYTVVAFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIE DPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICG IGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFF PAGDCFRKQYEDQLG NT seq 14628 nt NT seq  +upstreamnt  +downstreamnt atggccgaagggggagaaggaggcgaggacgagatccagttcctgcggactgaagatgaa gtggttctccagtgcatcgccaacattcacaaggagcaacggaagttctgcctggcagct gagggtctggggaaccgcctgtgcttcttggaacccacttcagaagccaagtatgttcct ccagatctctgcgtctgcaattttgtcctggaacagtccctgtctgtcagagccctgcag gaaatgcttgccaacacagttgaaaatggtggagaagggctcagtgacctctcggaatgg gcagctcaagggggtggccacaggaccctgctgtatggccacgcgattctcctgaggcac tccttcagtggaatgtatttaacatgtttaacaacatcaagatcacaaacagataaactt gcctttgatgttggtctgcgggagcatgccacaggagaagcctgctggtggaccatacac cctgcttccaaacagaggtctgagggagagaaagttcgaattggtgatgacctcatcctt gtaagtgtgtcctccgaaagataccttcatctctcagtctcaaatggtaacatacaagtg gatgcctcctttatgcaaacactctggaatgtacatcccacctgctcaggaagtagcatc gaagaaggttatcttcttggtgggcatgtagtacgtcttttccacggccatgatgagtgt ttgacaataccatctacagaccagaatgattcgcagcacaggaggatattctatgaagca ggaggagccgggacgcgagccaggtctctgtggagagtagaaccccttcgaataagctgg agtggcagtaacatcagatggggccaggcttttcgtcttcggcacctaactacaggtcac tacttggccttgacagaggatttaggtcttattctgcaagatcgtggcaaatcagacaca aagtccacagccttctctttccgggcatcaaaggaaatcaaggagaaatcagattccact cacaagcgagatatagaaggcatgggagttccagaaataaagtacggagattctgtctgc tttgtccagcatatagccagtggtctttgggtgacttacaaagcacaagatgccaaaaca tcccgccttggacccctaaaaagaaaggtcatactccatcaagaaggccacatggatgat ggattgacactgcagaggtgccaacgggaagagtcccaggctgctcgaatcatccggaac acaactgccttattcagccagtttataagtggaaacaatcgcactgcagcccctgtcagt ctgccaatagaagaggtcctgcagaccctacaggatctaatcgcctacttccagcccccg gaagaggaaatgcagcatgaagacaagcagaacaaacttcgctcactcaaaaacagacag aatcttttcaaggaagagggaatgttggctctcgtgttaaattgcattgatcgcttgaac gtctacaacagtgtcacacactttgcagggatcgcaagagaagaaagcagcatggcttgg aaagaagttctcagcctcctgtataaattgctggctgctctcattcgaggaaatagaaac aattgtgctcagttctccaataaccttgattggttaatcagcaaattggacagactcgaa tcttcctcaggtatcttggaagttttgcactgcattctgattgaaagcccagaagcctta aatttaattgcagagggtcacatcaagtccataatctccctgttggacaagcatgggcgg aatcacaaggttctggatgtactgtgttccctgtgcttgtgcaatggggttgctgtgaga gccaaccagaatctcatctgtgacaacttgttgccccggagaaacctgctcctgcagaca cggctgattaatgatgtgaccagtatacggccaaacatctttttgggagtggctgagggc tcggcacagtacaggaagtggtacttcgagctgattatcgaccaagtagactccttcctg acagcagaacccacacatcttcgagtgggctgggcctcctcttcaggctatgctccctac cctggcggtggagaaggatggggaggcaatggtgttggtgatgacctgtactcctacggt tttgatggacttcacctttggtcaggccggatacccagagctgtggcctccatcaaccag cacctcctgaagtcagatgacgtggtgagctgttgcctggatcttggagttcctagtata tctttccgcatcaatggtcagcctgtgcaaggaatgtttgagaacttcaacacagatggg ctcttcttccctgtggtgagcttttcagcaggtgtcaaagtacgttttctgatgggtgga cgtcatggagaatttaagttcctgcctccctctggctatgctccttgctatgaagcctta cttccaaaagagaagatgagattggagcctgtgaaagaatataagcgtgatgctgaaggt gttagagatctactgggtaccacccagttcctctcccaggcctctttcatcccatgtccc atagacaccagtcaggtagtgttaccacctcatcttgagaagatccgagacagactagct gaaaacatccatgagctttgggggatgaataaaattgagcttggctggacttttggcaag atacgggatgacaataaaagacaacacccctgccttgtggagttttcaaagctccctgaa acagagaagaattataacctgcaaatgtcaacagaaaccttaaaaaccctcctggccctt ggatgccacattgcccatgtaaatccggctgctgaagacgatctcaagaaagtgaaactt cccaaaaattatatgatggccaatggctataaaccagcccctttggatttgtctgatgtg aaattgttacctcctcaagaaattttagtggataagcttgcagagaatgcccataatgtt tgggcaaaggaccgaataaaacaaggatggacctatggcattcaacaggatttgaagaac aaaaggaatccccgcttagtgccatacgcattactggatgagagaaccaagaagtcaaac agagatagccttcgagaagctgttaggacattcgttggctatgggtataacattgaaccg tcagatcaagaacttgctgacccagctgtggaaaaagtcagcatagacaagatcagattt ttccgggtagagcggtcttacgctgtgaggtctggaaagtggtatttcgagttcgaagtc gtgactggaggagatatgcgtgttggttgggccaggcctggctgtcgatctgacattgag ctgggggctgatgaccaagcctttgtatttgaaggcagcaggggtcaacgctggcaccag ggaagtgggtattttggacgaacctggcagccaggagatgtggttggatgtatgattaac ctggaggatgcttcgatgatcttcacactgaatggggagcttctgatcaccaacaaaggc tcagaacttgcctttgctgactacgagattgaaaatggctttgtgcccatctgctccctg ggcctttctcagattggtcgcatgaatcttgggatggacgccagtaccttcaagttttat accatgtgcggcctccaagagggctttgagccttttgctgtcaacatgaaccgagatgtt gccatgtggttcagcaagcgcctcccaacgtttgtcaacgtgcctaaggatcatccgcat atagaggttgtaaggatcgatggcaccatggacagccccccgtgcctcaaggtgacccac aaaacatttggcacacagaagagcagtgccaacatgatctactgccgcctaagcatgcct gttgagtgtcactcctccttcagccacagcccctgcctggacagcgacactttccagaag aggaaacagattcaggaaatgctctctcatacaacaacacagtgctactatgcaatccgc atctttgctggacaggacccctcctgcgtttgggttggatgggtgactccggactatcat ttgtacagtgaaaagtttgacctgagtaaaaactgtacagtgactgttaccctgggagat gaaagaggccgggtccatgaaagtgtgaagcgcagcaactgctacatggtctggggtggg gatgtcgttgccacatcccaaagatcaagtcgaagcaatgtggacctagagattggctgc ctcgtggatctggcaatgggcatgttgtccttttcagccaacgggagagaactcggcacc tgctaccaggtggagcccaacaccaaagtgttcccagcagttttcctgcaacctacgagc acttctttgtttcagtttgaactggggaagctaaagaatacaatgccgctgtcggcagcc atatttaaaagtgaagagaagaacctagtgcctcagtgtccccctcggcttgacgtccaa accattcagcctgtgctctggagccgcatgccgaacagctttctgaaagtggagactgag cgggtgagcgagcgccatggctgggtggtacagtgcctggagccattgcagatgatggca ctctacatccctgaggagaacaggtgtgtggatatcctagagctttgtgagcaggaggac ctgatgcggttccatttccacacactgagactctacagcgctgtgtgtgccctgggaaac agccgagtggcttacgccttgtgtagccacgtcgacctctcccagctcttctacgccatt gacaacaagtacctccctggcctccttcggtctggtttctatgacctgctcatcagcatc cacctcgccaatgccaaggagaggaagcttatgatgaagaatgaatacattatccccatt accagcaccaccaggaaaatccacctgtacccagatggatccaagaggcacggattgcct ggggtaggcctaagaacatgcctcaagccagggttcaagttctccaccccttgctttgtt gtgaccagcgaagagcaccagaaacagagtcctgagattcccctagagattctcaagaca aaagcactgaccatgctgacagaagcagtgcagtgcagtggggctcacatccgggaccca gttgggggatctgtggagttccagtttgtgcctgtgctgaaactcatcggaaccttgctg gtcatgggggtatttgatgatgatgacattcggcatatcctccttctcatcgatccctct gtatttggggagcacagtggagagacagaggagggagctgagaaggaggaagtggcccag gaggaggagaaagctgtggaggctggggaaaaggccagcaaggaggctccagtcaaaggc ttgctgcagacacgattaccggaatccgtcaaactgcagatgtgcgagcttctcagctat ctctgtgattgtgaactacagcaccgagtggaggccattgtggcatttggtgatatttat gtctccaagctccaggcaaatcagaagttccgctacaatgagctcatgcaagccctgaac atgtctgcagccctgactgcccggaagaccagggagttccgctcacccccacaggagcag atcaacatgctgcttaactttcaactgggggagaactgcccctgtccagacgagattcgg gaagagctctacgatttccatgaggacctgctcgttcactgcggggttcccttggaggaa gtggaggaggaggaagaggacacctcctggactgggaagctccgtatgctgatgtcaaag gtcaaaggaccccccaagctggagaagaagcaaccaagggaggaggaggagcaataccct accactctcaaggagctcatctcacagacaatgattcgctgggcccaggaggaccagatc caggatgcagagctcatccgcatgatgttcaacctgctccggaggcagtacgacagcatc ggggagctgctgcaggcactgcggaagacctacaccatcagccaggcgtctgtgagtgac acaatcaacctgctggcagccctgggccagatccgctgcctcctcagcgtcagaatgggc aaggaagaggagcttcttatgatcaacggcctgggagacataatgaacaacaaggtgttt taccagcaccccaacctcatgcgcgtccttggcatgcacgagactgtgatggaggtgatg gtgaacgttctgggagcagagaagtcccagattgcttttccgaagatggttgctagttgc tgccgcttcctttgttatttctgtcgaattagccggcaaaatcagaaggccatgtttgag catctaagttacctactggagaatagcagtgtcggtctagcgtccccttctatgagggga tccaccccattggatgtggcagcttcctctgtaatggacaacaacgaattagcactgggc ttagaggaaccagacctcgagaaggttgtgacctacttggcaggctgtggcttgcagagc tgtcctatgcttctggccaaaggataccctgatgttggctggaatcccattgaaggagag cggtatctatctttcctgagatttgctgtcttcgtgaacagtgaaagtgtggaggaaaat gcaagtgtcgtggtcaaactactcatcagacgcccagaatgctttggtcctgccttgagg ggtgaaggaggaaacggtctgttggctgccatgcagggcgccattaagatctcagagaac ccagcccttgacctgccctcacagggatataagagagaaatcagtgtggaagatgatgaa gatgaagaagagattgtgcacatgggaaatgcaattatgtcattttattctgctctcata gatcttctaggccgctgtgctcccgaaatgcatcttatacagacaggaaaaggggaagcc atccggatcaggtcaatcctgcgctccctagtccccacagaggacttggttgggatcatc agcatccccctgaaactgccatccctgaacaaagatgggtcagtgagcgagccagacatg gcggccaacttctgtcctgaccataaggctcccatggtgctcttcctggatcgtgtgtac ggcatcaaggatcagacttttctactccacttgctggaggttggctttttacccgattta agagcctccgcctctctagatacagtctctctaagcaccacagaggcagcgctagcactc aatcggtatatatgttctgcagtgctcccactgctcaccagatgcgccccactctttgcc ggaactgagcacttctcctctttgattgattccacacttcagaccatctacaggctttcc aagggccgttccctcactaaggcccaaagggacaccattgaagaatgtttgctcgccatt tgcaatcacttgagaccttccatgttacaacaactcctgcgacgtcttgtttttgatgtc ccacagctcaatgaatactgcaaaatgcctctgaagcttctgacaaatcactatgagcag tgctggaagtattactgtctgccttcaggatgggggagctatggtctcgctgtggaggag gaactgcacctgacggagaagctcttctgggggatttttgactccctctcccataagaaa tatgacccggatcttttccgaatggccctgccttgtctcagtgctatagctggggccttg ccaccagattatttagacaccagaatctcagccacattggagaaacaggtctcagtggat gcagaaggcaactttgaccccaaacctatcaacaccatgaatttctccttgcctgaaaaa ctggagtacatcgtcaccaagtatgctgagcattcacatgataaatgggcctgcgacaag agtcagaacggatggaaatatggaatttccctggatgaaaatgtgaggacccatcccctg ataagacctttcaagacattaacagagaaggaaaaggaaatctaccgctggccagccaga gagtccctgaaaaccatgttggctgtggggtggactgtcgaaagaactaaagaaggagaa gccttggttcaacagcgggaaaatgagaagcttcgaagcatgtcccaggctagccagggc aacagctatagccctgttcccctggacctttccaatgttgtgttatccagagagctccag ggcatggtggaagtcgtggccgagaactaccataatatctgggccaagaagaagaaattg gagctggagagcaaaggtggtggaagtcaccctcttttagtgccctatgacaccttgaca gccaaggaaaagttcagagatcgagagaaggcacaggacctattcaaattcctccaggtg aatggcatcacagtttctagaggaatgaaggatttggagctggatgcttcttctatggaa aagagatttgcctataaatttttgaagaagatcctaaaatacgttgactctgctcaggag tttattgctcatttagaagccattgtcagcagtgggaaaactgaaaagtctccccatgac caggagatcaaattctttgccaaagttctcctccctctagttgaccagtacttcaccaat caccgcctctacttcctgtcatcccctctgaagcccctgagcagcagtgggtatgcctcc cataaggagaaggaaatggtggccagcctgttctgcaaactcgctgctcttgttagacac aggatttccctctttgggagcgattctactacaatggtgagctgtctgcatatcttagct cagacgcttgacacacggactgttatgaagtcaggctccgagctggtgaaagctggcttg cgagccttttttgaaaatgctgccgaagacttagagaagactttggaaaacctgaagctg ggaaagtttacccattccagaacacagattaaaggtgtttctcagaatatcaactatacc acagtggctctgctccccatcctcacctcaatcttcgaacacgtggcccagcatcagttc ggggtggatttgctcttgggcgacgtgcagatttcatgctaccatatactgggaagtctg tactcccttgggacaggaaagaacatctatgttgaaaggcaacgccctgcccttggagaa tgtctggcctcactggtagcagctattccagtggcattcctggagcccacccttaaccgc tataatcctctctctgtcttcaacaccaagacccccagggagagatctatcttggggatg ccagacacggcagaggagatgtgtcctgacattccacagctggacggcctgatgaaggaa atcaacgcactagccgagtccggggcccggtacacggaaatgccccacgtcattgaggtg atcttgcccatgctctgcaactacctgtcctactggtgggagcgggggcctgagcaccag ccccccagcacagggccctggtgcaccaaggttacctctgaacacctcagtgtcatcctg ggcaacattctgaaaatcatcaacaacaacctgggcatcgacgaggcctcctggatgaag cgaatcgcagtgtatgcccagccgatcatcagcaaagccaggcctgacctgctcagaagc cactttatcccaactctggagaagctgaagaaaaaggctgtcaagactgtgcaggaggaa gagcagctgaaagcagatagcaaaggggacactcaggaggcagagttgctcattctggat gagtttgcagtgctctgcagggacctctacgccttctaccccatgctgatccgctatgtg gacaacaacagatctaactggctcaaaagccctgatgctgattccgaccagctcttccgc atggtggcagaggtcttcatcctgtggtgtaaatctcataacttcaagagggaagagcag aattttgtgattcagaatgaaattaataatttggcgtttttgactggagacagcaaaagc aagatgtcaaaatctggaggccaggaccaggagcggaagaagaccaagcggcggggggac ctgtattccatccagacctccctcattgtggcagcgctcaagaagatgctgcccattggt ttgaatatgtgcacccctggtgatcaggaattgatctccctcgcaaaatcacggtacagc tatagagacacagatgaagaggtcaaggagcatctgcggaataacttgcacttgcaggaa aagtctgatgaccccgctgtcaagtggcaactgaacctctacaaagatgttttgaagagt gatgagccttccaatccagaaaagacagtggagcgtgtgcagagaatttctgcagctgtc ttccatctggagcaggtggagcagcctctcaggtccaagaaggctgtgtggcacaaacta ttgtcaaagcaacgcaagcgggctgtggtggcctgtttcaggatggcacctctctacaat ctgcccaggcaccgctctattaacctcttcctccatggctatcagagattttggatagaa acagaggagtattcctttgaagagaaactagtacaggatttggctaaatctcccaaggtg gatgaggagaaggaggaggaggaggagatggaaaagcagccggacccactccatcagatc gtcctacatttcagccgaaatgccctcacagagaggagcaaactggaagatgatcctttg tatacttcctattccagcatgatggccaagagttgtcagagtggggaagatgaagacgag gaggaagacaaggaaaaaacatttgaagagaaggagatggaaaagcagaaaaccctttat cagcaggctcgactgcatgagcgtggagcagcagaaatggtcctgcagatgataagcgcc agcaaaggtgagatgagccccatggtggttgagacgctgaagctgggcatcgccatcctg aatgggggcaatgcaggcgtgcaacagaaaatgctagattacctaaaagagaaaaaggat gctggattctttcaaagcctttctggtcttatgcagtcttgcagtgtccttgatttgaat gcatttgagcgacagaataaagctgaaggtctagggatggttactgaagaaggaacactc attgttcgtgagcgtggtgacaaagtactccagaatgatgagtttacacgagatctcttt agattcctacagttactttgtgaaggacataatagtgactttcagaacttcctgcggacc caaatgggcaacaccaccactgtgaatgttatcatcagcactgtggactatcttctgcgt ctgcaggaatccatcagtgatttctactggtattattctgggaaggacatcattgatgaa tctggacagcacaatttttccaaagctttggcagtcactaagcagatttttaactctcta acagaatatatccagggcccttgcattggaaaccagcagagcctggctcacagcaggctg tgggacgcagtggtcggcttcctccatgtctttgctaacatgcagatgaaactctctcag gattccagtcagatcgagctgctgaaggaactcttggatctccttcaggacatggtggtg atgcttctgtccctcctggaagggaatgtggtaaatggaactattggcaagcagatggtt gacacactggtagaatcatctaccaatgtagaaatgatcttgaaattctttgacatgttc ttgaaacttaaagacttaaccagctcagataccttcaaagaatatgacccagatggtaaa gggattatctccaaaaaagagttccaaaaggccatggaagggcaaaaacagtatacccag tcagaaattgactttctcctctcatgtgcagaagccgatgagaatgatatgtttaattac attgattttgtagaccagttccatgagccggccaaggacatagggtttaatgtggcagta ttattgacaaatctttctgaacatatgcctaacgattctcgccttaagtgtttgttggac ccagcagaaagtgtgctcaattactttgaaccttacctaggacgcattgaaatcatgggt ggggccaagaaaattgagcgtgtttattttgagatcagtgaatccagtcgaactcagtgg gaaaaaccccaagtgaaggaatctaagagacagttcatctttgatgttgtcaatgaaggt ggagagcaagaaaaaatggaactatttgtgaacttctgtgaggacaccatcttcgaaatg cagctagcatcacagatctcagaatcagactcagccgagaggccagaagagcaagaggaa gaagaggaagatccttcatacacattagaaatggaaggtgtagaggtggaggacacttct tttgagtctgtctctgcatttgctatggcctgtgctgctgtaaagaaaaatgttgccaac tttctgaaaaaggcaaccctgaaaaacctcaggaaacagtacaggaaggtgaaaaagatg actgtaaaggagctagtgaaggtgtttttttcatttttttggatgttgtttgtgggtctg ttccaattattcttcaccatactgggaggaatcttccaggtcctctggagcacagtgttt ggagggggcctggtagaaggggcaaagaacatcagggtgaccaagatcctgggtgatatg cctgacccaacccaatttggtatccatgatgatgctatggagggtgagagggcagaagtg actgagccaggtatcacaactgaactagtacacttcgtaaaaggtgagaagggcgatgca gatcttatgtcagatctctttggattccaccaaaagaaagaaggtggcgtaaagcatggg cctgaagtgggtttaggtgatctctctgagattatcggcaaggatgagcctcctacacta gaaagtactgtacggaaaaaaaggaaagcacaggcagcagaaataaaggcagcacgtgat gccgaaggaaaagtcgactctgagaaggcagatgtggaagatggggagaaggaggataga gccaaagaagaggaacaggctgagaccttatgggcagaaacaacaaaaaagaagaagcga cggcgtggccagaaagttgagaagcctgaagccttcatggctaatttctttaaagggctg gaaatctatcagaccaagttactgcattacctggccaggaatttctacaacctgaggttt cttgctctgtttgtagctttcgctatcaacttcatcctgctcttttacaaggtcactgaa gaacctttagaggaagagtcagaggatgttgcaaacctgtggaattcctttcatgaggat gaggaggaagaagccatggtgttctttgtcctgcaggagagcactggttacatggcacca acgctgcgggccctggccattatccacactgtcatttccttggtctgtgtggtgggctat tactgcctgaaggttcctctagtggtgtttaaaagagaaaaagaaattgccaggaagctg gagtttgatggcctatatatcaccgaacagccatctgaagatgacatcaagggacaatgg gaccgcttagtaatcaacacaccgtcttttcctaataactactgggacaagtttgtaaag agaaaggtgatcaacaagtatggagacctctatggagcagaacgcattgctgagctcctg ggtttggataaaaatgccctggactttagcccagtagaagagactaaagctgaagcagcc tctcttgtgtcatggctgagttccatcgacatgaagtaccatatctggaagctgggagtt gtttttaccgataattcctttctctaccttgcctggtacactaccatgtcaatcctgggc cactacaacaacttcttctttgctgctcacctactggatattgcaatgggcttcaagact ctgaggactattctgtcatctgtaactcataatggcaaacagttggtgctgacggtcggt ctcctggctgtggtggtttatctctacacggtggtcgccttcaacttcttccgcaagttc tataacaaaagtgaagatgacgacgagccagatatgaagtgtgatgacatgatgacgtgt tacctattccacatgtatgtgggcgtgagagctggaggcggcattggtgatgaaattgaa gatcctgctggcgatccttatgaaatgtaccgcattgtctttgacatcaccttcttcttt ttcgttattgtcatcttgttggccatcatccaaggtcttatcattgatgcttttggagag ctaagggaccagcaggaacaagtgcgagaagatatggagactaaatgtttcatctgcggg attggcaatgactattttgacaccacccctcatggttttgagacacatacattacaagag cacaacttagccaactacctgttctttctgatgtacttgattaataaagacgaaacagaa cacacaggtcaggaatcttatgtctggaagatgtaccaagaaaggtgttgggatttcttc ccagctggtgactgctttcgaaaacaatatgaagatcagcttggataa

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