Sorex fumeus (smoky shrew): 130042645 Help Entry 130042645         CDS       T10594                                  Symbol NOS3 Name (RefSeq) nitric oxide synthase 3   KO K13242   nitric-oxide synthase, endothelial [EC:1.14.13.39] Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum00220   Arginine biosynthesis sfum00330   Arginine and proline metabolism sfum01100   Metabolic pathways sfum04020   Calcium signaling pathway sfum04022   cGMP-PKG signaling pathway sfum04066   HIF-1 signaling pathway sfum04071   Sphingolipid signaling pathway sfum04151   PI3K-Akt signaling pathway sfum04370   VEGF signaling pathway sfum04371   Apelin signaling pathway sfum04611   Platelet activation sfum04915   Estrogen signaling pathway sfum04921   Oxytocin signaling pathway sfum04926   Relaxin signaling pathway sfum04931   Insulin resistance sfum04933   AGE-RAGE signaling pathway in diabetic complications sfum05415   Diabetic cardiomyopathy sfum05417   Lipid and atherosclerosis sfum05418   Fluid shear stress and atherosclerosis Brite Enzymes [BR:sfum01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      130042645 (NOS3) BRITE hierarchy SSDB OrthologParalogGFIT Other DBs NCBI-GeneID:  130042645 NCBI-ProteinID:  XP_055990759 LinkDB All DBs Position Unknown AA seq 1203 aa AA seqDB search MGNLSSVGREPGPCGLGLGLGLGLCSKQGPASPAPPEPSRAPAPAPAPAPAPPPAADSPL LSRSLEGPRFPRVKNWEVGSIAYDTLSAQAQQDGPCTPTRCLGSLVLPRKPHSRGAPGPT APELLRQARAFIDQYYSSIKRGGSQAHALRLQEVEAEVAATGTYQLRESELVFGTKQAWR NAPRCVGRIQWGKLQVFDARDCNSAQEMFTYICNHIKYATNKGNLRSAITVFPQRVPGRG DFRIWNGQLIRYAGYRQQDGSVRGDPANVEITELCVQHGWSPGNGRFDVLPLLLQVPDEP PELFTLPPELVLEVPLEHPTLEWFAELGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMS TEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVD HHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPTFRYQPDP WKGSAAKGAGIARKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLG RLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNS SPRPEQHKSYKTRFNSISCSDQLVSTWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPH FCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAA ARDIFSPKRSWKRQRYRLSAQAQGLQLLPGLVHVHRRKMFQATVLAVENLQSSKSTRATI LVRLDTAGQEGLQYQPGDHVGICPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPGG PPPGWVRDPRLPPCTLRQALTFFLDITTPPSPRLLQLLSTLAEEPGEQQELETLSQDPRR YEEWKWFRCPSLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEIHLTVAV LAYRTQDGLGPLHYGVCSTWLSQLRAGDSVPCFIRGAPSFRLPPDPNLPCILVGPGTGIA PFRGFWQERLHDIDSKGLQPFPMTLVFGCRCSQLDHLYRDEVQDAQRRGVFGRVLTAFSR EPNSPKTYVQDILRTELAEEVHRVLCLEGGHMFVCGDVTMATSVLQTVQRILATEGNMEL DEAGDLIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERRRGAVPWAFDPPGLDT AGS NT seq 3612 nt NT seq  +upstreamnt  +downstreamnt atgggcaacctcagcagcgtgggccgggagccggggccctgcggcctggggctggggctg ggcctggggctctgcagcaagcagggtccggcctcgcccgcgccccccgagcccagccgg gcccccgcgcccgcgcccgcgcccgcgcccgccccgccgcctgcagccgacagccccctg ctctcccggtccctggagggacccaggttcccccgagtgaagaactgggaggtggggagc atcgcctatgacacgctgagcgcccaggcccagcaggacgggccctgcacccccacgcgc tgcctgggctccctggtgctcccgcggaagccgcacagccggggcgcccctgggcccacc gcccccgagctgctgcgccaggccagggccttcatcgaccagtactacagctccatcaag agaggtggctcccaggcccacgcgctgcgactgcaggaggtggaggccgaagtggcggcc acgggcacgtaccagctgcgggagagcgagctggtgttcgggaccaagcaggcctggcgc aacgccccccgctgcgtgggccgcatccagtggggcaaactacaggtgtttgacgcgcgg gactgcaactcggcccaggagatgttcacctacatctgtaaccacatcaagtatgccacc aacaagggcaacctccgctcggccatcaccgtcttcccccagcgtgtccccggccgcggg gacttccggatctggaacgggcagctgatccgctacgctgggtaccggcagcaggacggg tcggtgcggggggaccctgccaacgtggagatcaccgagctctgcgtccagcacggctgg agccccgggaacggccgcttcgacgtgctgccgctgctgcttcaggtgcctgacgagccc ccggagctcttcaccctgccccccgagctggtcctcgaggtgcctctggaacaccccacg ctggagtggttcgccgagctgggcctgcgctggtacgccctcccggccgtgtccaacatg ctgctggagatcgggggcctggagttccccgcggcccccttcagcggctggtacatgagc acggagatcggcacgcggaacctgtgcgacccccaccgctacaacatcctggaggacgtg gccgtgtgcatggacctggacacccggacgacctcatccctgtggaaggacaaggcggcc gtggagatcaacgtcgccgtgctacacagctaccagctggccaaggtcaccatcgtggac caccacgcggccacggcgtccttcatgaagcacctggagaacgagcagaaggcgcgcggg ggctgcccggccgactgggcctggatcgtgccccccatctcgggcagcctcacgcccgtc ttccaccaggagatggtcaactacgtgctgtccccgaccttccgctaccagccggacccc tggaagggcagcgcggccaagggggccggcatcgccaggaagaagaccttcaaggaggtg gccaacgcagtcaagatctccgcgtccctcatgggcaccgtgatggccaagcgcgtgaag gcgaccatcctgtacggctcggagacgggccgcgcgcagagctacgcacagcagcttggg agactcttccggaaggccttcgacccccgggtgctgtgcatggacgagtacgatgtggtg tccctggagcacgagacgctggtgctggtggtgaccagcacattcgggaacggggacccc ccggagaacggagagagttttgccgctgccctcatggagatgtcggggccctacaacagt tccccaaggccggagcagcacaagagctacaaaacccgcttcaacagcatctcctgctcc gaccagctggtgtccacgtggcgtcggaagcggaaggaatcgagtaacacggacagcgct ggggcgctgggcaccctcaggttctgtgtgttcgggctgggctcccgagcgtacccccac ttctgcgcctttgcccgcgcggtggacacgcggctggaggagctgggcggagagcggctg ctgcagctgggccagggggacgagctgtgtggccaggaggaggccttccgcggctgggcg caggccgccttccaggcctcctgcgagaccttctgcgtgggagaggacgccaaggcggcc gcccgcgacatcttcagccccaagcgcagctggaaacgccagaggtaccggctgagcgcc caggcccagggcctccagctgctgccaggtctggtccacgtgcacaggcggaagatgttc caggcgaccgtgctggcggtggagaacctgcagagcagcaagtccacccgcgccaccatc ctggtgcgcctggacacggccggccaggaggggctccagtaccagcccggggaccacgtg ggcatctgcccgcccaaccggcccggcctggtggaggcgctgctgagccgcgtggaggac ccgccgccgcccggggagcccgtggccgtggagcagctggagaagggcagcccgggtggc cctcccccaggctgggtgcgggacccccgcctgcccccctgcacgctgcgccaggccctc accttcttcctggacatcaccaccccgcccagcccgcggctgctgcagctgctcagcacg ttggccgaggagcccggggagcagcaggagctggagaccctcagccaggacccccggcgc tacgaggagtggaagtggttccgctgcccgtcgctgctggaggtgctggagcagttcccg tccgtggcgctgcccgcgcccctgctcctcacgcagctgcccctgctgcagccgcgctac tactcggtcagctccgcgcccagtgctcaccccggcgagatccacctcacggtggccgtg ctggcctaccgcacgcaggacggcctgggtcccctgcactacggagtctgctccacgtgg ctgagccagctcagggccggagacagcgtcccctgcttcatcaggggggctccctccttc cggctaccccctgaccccaatttgccctgcatcctggtgggcccgggcactggcatcgcc cccttccgggggttttggcaagagcggcttcatgacattgacagcaaagggttgcagccc ttcccgatgaccttggtgttcggctgccgatgctcccagctcgaccatctctaccgcgac gaggtgcaggatgcccagcggcgcggggtgttcggccgcgtcctcacggccttctcccgg gaacccaacagccctaagacgtatgtgcaggacatcctcagaacggagctggccgaggag gtgcaccgcgtgctgtgcctagagggaggccacatgttcgtctgcggggacgtcaccatg gcaaccagtgtcctgcagacggtgcagcgcatcctggccaccgagggcaacatggagctg gacgaggccggcgacctcattggcgtgctgcgggatcagcaacgctatcacgaggacatt ttcgggctcaccctacgcacccaggaggtgacaagccgcattcgcacccagagcttctcc ctgcaggagcgacgccggggagcagtgccctgggcttttgaccccccgggtctagacact gcaggctcctga

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