Sorex fumeus (smoky shrew): 130042783 Help Entry 130042783         CDS       T10594                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase type 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum00230   Purine metabolism sfum01100   Metabolic pathways sfum01522   Endocrine resistance sfum04015   Rap1 signaling pathway sfum04020   Calcium signaling pathway sfum04022   cGMP-PKG signaling pathway sfum04024   cAMP signaling pathway sfum04062   Chemokine signaling pathway sfum04072   Phospholipase D signaling pathway sfum04081   Hormone signaling sfum04082   Neuroactive ligand signaling sfum04114   Oocyte meiosis sfum04211   Longevity regulating pathway sfum04213   Longevity regulating pathway - multiple species sfum04261   Adrenergic signaling in cardiomyocytes sfum04270   Vascular smooth muscle contraction sfum04371   Apelin signaling pathway sfum04540   Gap junction sfum04611   Platelet activation sfum04713   Circadian entrainment sfum04714   Thermogenesis sfum04723   Retrograde endocannabinoid signaling sfum04724   Glutamatergic synapse sfum04725   Cholinergic synapse sfum04727   GABAergic synapse sfum04750   Inflammatory mediator regulation of TRP channels sfum04911   Insulin secretion sfum04912   GnRH signaling pathway sfum04913   Ovarian steroidogenesis sfum04914   Progesterone-mediated oocyte maturation sfum04915   Estrogen signaling pathway sfum04916   Melanogenesis sfum04918   Thyroid hormone synthesis sfum04921   Oxytocin signaling pathway sfum04923   Regulation of lipolysis in adipocytes sfum04925   Aldosterone synthesis and secretion sfum04926   Relaxin signaling pathway sfum04927   Cortisol synthesis and secretion sfum04928   Parathyroid hormone synthesis, secretion and action sfum04934   Cushing syndrome sfum04935   Growth hormone synthesis, secretion and action sfum04961   Endocrine and other factor-regulated calcium reabsorption sfum04962   Vasopressin-regulated water reabsorption sfum04970   Salivary secretion sfum04971   Gastric acid secretion sfum04972   Pancreatic secretion sfum04976   Bile secretion sfum05032   Morphine addiction sfum05163   Human cytomegalovirus infection sfum05166   Human T-cell leukemia virus 1 infection sfum05200   Pathways in cancer sfum05207   Chemical carcinogenesis - receptor activation sfum05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:sfum00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     130042783 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     130042783 (ADCY9)    04371 Apelin signaling pathway     130042783 (ADCY9)    04020 Calcium signaling pathway     130042783 (ADCY9)    04072 Phospholipase D signaling pathway     130042783 (ADCY9)    04024 cAMP signaling pathway     130042783 (ADCY9)    04022 cGMP-PKG signaling pathway     130042783 (ADCY9)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     130042783 (ADCY9)    04081 Hormone signaling     130042783 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     130042783 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     130042783 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     130042783 (ADCY9)    04062 Chemokine signaling pathway     130042783 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     130042783 (ADCY9)    04923 Regulation of lipolysis in adipocytes     130042783 (ADCY9)    04912 GnRH signaling pathway     130042783 (ADCY9)    04913 Ovarian steroidogenesis     130042783 (ADCY9)    04915 Estrogen signaling pathway     130042783 (ADCY9)    04914 Progesterone-mediated oocyte maturation     130042783 (ADCY9)    04921 Oxytocin signaling pathway     130042783 (ADCY9)    04926 Relaxin signaling pathway     130042783 (ADCY9)    04935 Growth hormone synthesis, secretion and action     130042783 (ADCY9)    04918 Thyroid hormone synthesis     130042783 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     130042783 (ADCY9)    04916 Melanogenesis     130042783 (ADCY9)    04925 Aldosterone synthesis and secretion     130042783 (ADCY9)    04927 Cortisol synthesis and secretion     130042783 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     130042783 (ADCY9)    04270 Vascular smooth muscle contraction     130042783 (ADCY9)   09154 Digestive system    04970 Salivary secretion     130042783 (ADCY9)    04971 Gastric acid secretion     130042783 (ADCY9)    04972 Pancreatic secretion     130042783 (ADCY9)    04976 Bile secretion     130042783 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     130042783 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     130042783 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     130042783 (ADCY9)    04727 GABAergic synapse     130042783 (ADCY9)    04725 Cholinergic synapse     130042783 (ADCY9)    04723 Retrograde endocannabinoid signaling     130042783 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     130042783 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     130042783 (ADCY9)    04213 Longevity regulating pathway - multiple species     130042783 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     130042783 (ADCY9)    04714 Thermogenesis     130042783 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     130042783 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     130042783 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     130042783 (ADCY9)    05163 Human cytomegalovirus infection     130042783 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     130042783 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     130042783 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     130042783 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     130042783 (ADCY9) Enzymes [BR:sfum01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      130042783 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Motif Other DBs NCBI-GeneID:  130042783 NCBI-ProteinID:  XP_055990949 LinkDB All DBs Position Unknown AA seq 1353 aa AA seqDB search MASPPHQQLLPHHGTEVSCDSSGDSSSVRVKINPKQLVSNSHAKHCKHSISSSCSSSGDS GGGPRRAGAGGRLRRRRKLPQLFERASSRWWDPRFDSVNLEEACLERCFPQTQRRFQCAL FYIGFACLLWSVYFAVHMRPRLTAMVAPALGFLAVCVGFFLFTFTKLYARHYVWTSLVLT LLVSALTLAAQLQVLGPDSGRVDSSNHTPAAKPTDTCLSPVGSFSMCIQVLFLLYTVMHL PLYLSVFLGAAYSVLFETFGYYFQNEGCFPPPGLGAPHLELLSRALLHVCVHAIGIHLFV MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMRQGDEESENSIKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVTERLGQSVVADQLKGLKTYLIAGHRAKATHCSCSEAWLSGPEATDGSQVS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPPLDTGAEGGAMQNGCQEEPRN GTKASGGANSKSQNGLLSPPPEERLTTSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPISQFSLSFLDQELERAYRTSYQQEVIRNAPVRTF ASATFSSLLDVLLSTVVFLILSVTCFLKHGAAASPPPPAALAVFGAALLLELLSLVVSVR MVFFPESVMTCTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHVTSEFETNIQLTVFTGS AVLIAVVHYCNFCQLSSWMRSALATAVGAVPLLALCLSLCPDSSIVISHLDAVQNFSTER SPCNSSLPRDSRRPASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDNGAVIFASIVNFSEFYEENYEGGKE CYRVLNELIGDFDELLGRPDYSSIEKIKTIGATYMAASGLNATQAADGSHPQEQLRSLFE FARELMRVVGDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLFPKCTDNGGVPQHQLSISP DIRVQVDGSIGRSPTDEIANLVPSVQSLEKTPLGPDDSAQAKDTQPVSKRPWKEPARAEE RARLSRALESSDCDDVGLEEANELTRLNLSPRV NT seq 4062 nt NT seq  +upstreamnt  +downstreamnt atggcctccccgccccaccagcagctgctgccgcaccacggcaccgaggtgagctgcgac tcgagcggggacagcagcagcgtcagggtcaagatcaaccccaagcagctggtgtccaac agccacgccaagcactgcaagcacagcatctcctccagctgcagcagctccggggactcg ggcgggggtccccggcgagcgggggccgggggccgcctgcggcggcggaggaagctgccc cagctgttcgagagggcgtccagccgctggtgggacccccgcttcgactcggtgaacctg gaggaggcctgcctggagcgctgcttcccgcagacccagcgccgcttccagtgcgcgctc ttctacatcggcttcgcctgcctgctctggagcgtctacttcgcggtgcacatgcgaccc aggctcacggccatggtcgcccctgccctgggcttcctcgccgtgtgcgtgggcttcttc ctgtttaccttcaccaagctctacgcccggcattacgtgtggacctcgctggttctcacc ctcctggtgtccgccctgaccctggcggcccagctgcaggtcttggggcctgactcagga cgtgttgacagctccaatcacactcccgcggccaagcccacggacacttgcttgtctcca gtggggagcttttccatgtgcatccaagtgctcttcctgctctacaccgtcatgcactta cctttgtacctgagcgtgttcctgggagcagcctactccgttctgttcgagaccttcggc tactatttccaaaacgaaggttgcttccccccgcccggcttgggggccccacacttggag ctgctgagccgggccctgctccacgtctgtgtccatgccatcggcatccacctgttcgtc atgtcccaggtgaggtcccgcagcacctttctcaaggtgggccagtccatcatgcacggg aaggacctggaggtggagaaagccctcaaggagcggatgattcactcagtgatgccaaga atcatcgcagatgacttgatgaggcagggggacgaggagagtgagaattccatcaaaagg cacgccacctcgagccccaagaacaggaagaagaagtcgtccatccagaaggcccccata gccttccgccccttcaagatgcagcagattgaagaagtcagcattttgttcgcagatatc gtgggcttcaccaaaatgagtgccaacaagtctgcccatgcgctggtgggtctcctgaat gatctctttggccgcttcgaccgcttatgtgaagagaccaagtgcgagaagatcagcacc ctgggagactgctactactgcgtggcggggtgtcctgagccccgagctgaccatgcttac tgctgcatcgagatgggcctgggcatgatcagagccattgagcagttctgccaggagaag aaagagatggtaaacatgcgtgtcggggtacacacaggcactgttctgtgtggcatcttg ggtatgaggaggtttaagttcgacgtgtggtccaacgatgtgaacctggccaatctcatg gagcagctgggagtggccggcaaggtgcacatttccgaggccactgcaaaatacctagat gaccggtacgagatggaagatgggaaggtcaccgagcgcctcggccagagcgtcgttgcc gaccagttgaaaggtttgaagacatacctgatagcgggtcacagagcgaaggcgactcat tgcagctgctcagaggcctggctttctggtcccgaggccactgatggctcacaggtgtcc tcaggccctaggggacaggggacagcgtcaccagggagtgtcagtgacttggcacagact gtcaaaacctttgataaccttaagacctgcccttcgtgtggaatcacgtttgcacccccg ttggacactggcgcagagggaggagcgatgcagaacggctgtcaggaggagcccaggaat ggcactaaggcttccggaggagccaactccaagtcgcagaatggactgctgagcccgccc ccggaggagcgactcaccaccagccagacatccctgtgtgagatcctccaggagaaaggg cgctgggcgggcgtgagcctggaccagtcggcactgctgccgctgaggttcaagaacatc cgcgagaagacggatgcccacttcgtggacgtcatcaaggaagacagcttgatgaaagat tactttttcaagccgcccatcagtcagttcagcctgagtttcctggaccaggagctggag cgtgcctacaggaccagctaccagcaggaggtgatcagaaatgctcccgtgaggaccttt gccagcgccaccttcagctccctgctggacgtgctcctgtccacggtggtgttcctgatt ctctctgtcacctgcttcctgaagcacggggccgccgcctcgccccccccacctgccgcc ctggccgtgttcggggccgccctgctgctggagctgctgtctctcgtggtctctgtcagg atggtgttcttccctgagagtgtcatgacctgcaccaagcgcctgctggagtggatcgca ggctggctccctcgccactgcatcggggccatcctggtgtcactccctgccctggctgtc tactcacatgtcacctcagagtttgagacaaacatacagctcaccgtgttcacgggctcg gccgtcctgatcgccgtagtgcattactgcaacttctgccagctcagctcctggatgagg tcggccctggccactgcagttggggctgtgcccctgcttgcactctgcctttccctgtgc ccggacagttctatagtcatttcgcatcttgatgccgttcagaatttcagcactgagcgg agcccctgtaacagttccctgccacgcgacagccggcggccggccagcctcatcggccag gaggtgatcctggtcttcttcctcctgctactgctcgtctggttcctgaaccgggaattc gaggtcagctaccgcctccactaccacggggacgtggaggccgacctccaccgcaccaag atccagagcatgcgcgaccaggccgactggctgctgcggaacatcatcccctaccacgtg gccgagcagctcaaggtctcccagacctactccaagaaccacgacaacggcgccgtcatc ttcgccagcatcgtcaacttcagcgagttctacgaggagaactacgaggggggcaaggag tgctaccgcgtgctcaacgagctcatcggcgacttcgacgagctcctgggccggcccgac tacagcagcattgagaagatcaagaccatcggggccacgtacatggcggcgtcgggactg aacgccacgcaggcggcggatggcagccacccacaggagcagctgcgcagcctcttcgag tttgccagggagctgatgcgggtggtgggcgacttcaacagcaacatgctctggttcaac ttcaagctcagggtgggcttcaaccatgggcccctcacggcgggcgtcatcggcaccacg aagctgctgtacgacatctggggggacacggtgaacatagccagcaggatggacacgact ggcgtggagtgccgcatccaggtgagtgaggagagctatcgggtcctgagcaagatgggc tacgactttgactacagaggcacggtgaacgtcaaggggaagggccaaatgaagacctac ctcttccccaagtgcacggacaacgggggcgtgccgcagcaccagctgtccatctcccca gacatccgggtccaggtggacggcagcatcggacggtctcccacagacgagattgccaac ctggtgccttccgtccagagcttggaaaagacaccgctgggtcccgacgacagcgcgcag gccaaggacactcagcccgtgtctaagagaccctggaaggagccggccagggccgaggag cgcgcccggctcagcagggccctggagagcagcgactgtgacgacgtggggctggaggag gccaacgagctcacccgactcaacctctccccccgcgtgtga

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