Sorex fumeus (smoky shrew): 130042936 Help Entry 130042936         CDS       T10594                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum04072   Phospholipase D signaling pathway sfum04115   p53 signaling pathway sfum04140   Autophagy - animal sfum04150   mTOR signaling pathway sfum04151   PI3K-Akt signaling pathway sfum04152   AMPK signaling pathway sfum04211   Longevity regulating pathway sfum04218   Cellular senescence sfum04714   Thermogenesis sfum04910   Insulin signaling pathway sfum04919   Thyroid hormone signaling pathway sfum05163   Human cytomegalovirus infection sfum05165   Human papillomavirus infection sfum05168   Herpes simplex virus 1 infection sfum05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:sfum00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     130042936 (TSC2)    04151 PI3K-Akt signaling pathway     130042936 (TSC2)    04152 AMPK signaling pathway     130042936 (TSC2)    04150 mTOR signaling pathway     130042936 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     130042936 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     130042936 (TSC2)    04218 Cellular senescence     130042936 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     130042936 (TSC2)    04919 Thyroid hormone signaling pathway     130042936 (TSC2)   09149 Aging    04211 Longevity regulating pathway     130042936 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     130042936 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     130042936 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     130042936 (TSC2)    05163 Human cytomegalovirus infection     130042936 (TSC2)    05165 Human papillomavirus infection     130042936 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:sfum01009]     130042936 (TSC2) Protein phosphatases and associated proteins [BR:sfum01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      130042936 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  130042936 NCBI-ProteinID:  XP_055991186 LinkDB All DBs Position Unknown AA seq 1776 aa AA seqDB search MAKPAGKDSGLKEKFKIFLGLGPSRQHPRSAEGKQTEFVVTADILRELSVECGLNNRIRV IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPPEARHAVLTLLKAVVQGQGDRLGVLR ALFFRVIKDYPSNEDLPERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEHIASMVHMICLLCVQTVSPVDIEVSLQVLDAVVCYNCLPAESLPLFL VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAICNMCHIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLRNSPASVLPSFYEAMTCPNELVSYEIVLSITRLTKKYRRELQAVTWDI LLSIMERLLQQLQDLDSPELRTIVHDLLTTVEELCDQNEFHGSRERYFELVERYAGQRPE SSLLNLITYRAQSIHPAKDGWVHSLQALMDRFFRQEPRSAVRIKVLDVLSFVLLINRQFY EEELISSVVISQLCHIPEDRDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARPLS APPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYCLPASHAMRVYDLLVGHLQQHYKC SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPGKDGTVRFSPYCLCDSTEPDRGSEKASG PLSPPSGPPGVTPAGPAVRLGSLPYARLFRALLQCLKQETDWKVLKLVLSRLPESLRYKV LVFTSPCSVDQLSAALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHDYLD KARQRELVYCLEQGLIFRCASQCVVALAICSVEMPDVIIKALPVLVVKLTHISATASMAV PLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCR LPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRVARPPRQGLSHSP PVKELPESCAAEAFRCRSISVSEQVVRSRIQTSLTSASLGSADENSMAQADDNLKTLHLE LTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGAGTRSLL GLDAGELQGSPELSPGPSMQVRQTKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLRVGA LEAPAPHFPGSPAPAGPQSAPAAARQPAQKERTSLAAYVPLLTQGWAEILVRRPTGNTSW LMSLENPLSPFSSDITSMPLQELSNALMAAERFKERRDTALYKSLSVPAAGSAKPPPPPR SNTDSAVVLEEGGPDESMLAVEPPGLEDLGMALGTDGHGRHSTPFSRSSSTSSQEEKSLR GEEQSASGIPMARAVSSEGARPSADLSFEPAQPLSKSSSSPELQLLQDVLGGPGDKAGGG RLSPEAKARSQSGTLDGPSAPWLASGRESHGPGPAEGPSPASCPRSPSGLRPRGYTISDS APSRRGRRADRDSFKGRAGAGNTEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESFE RSVQLLDQIPSYDTHKIAVLYVGEGQSTNELAILSNEHGSYRYTEFLMGLGKLIELKDCQ PDKVYLGGLDVGGEDGQFTYCWHDDIMQAVFHIATLMPTKDGDRHRCDKKRHLGNDFVSI VYNDSGEDFKLGTIRGQFNFVHVIITPLDYECNLVTLQCRKDMEGLVDTSMAKIVSDRNL SFVARQMALHANMASQVHHSRSDPTDIYPSKWITRLRHIKRLRHRLREEAHSATPGLPLL QPPGHAKAPTPSPEPPYETGQRKRLISSVDDFTEFV NT seq 5331 nt NT seq  +upstreamnt  +downstreamnt atggccaagccggcgggcaaagactcggggctgaaggagaagttcaaaatctttctgggc ctgggcccctcgcgccagcacccccgctcggctgagggcaagcagacagagttcgtggtc acggcggacatcctgcgggagctgagcgttgaatgtggcctcaacaaccgcatccgggtg atagggcagatctgcgaagttgccaagacaaagaagtttgaggagcatgctgtggaggca ctctggaaggccgttgctgacctgctgcagccggagcggccacccgaggcccggcacgcg gtgctgactctgctcaaggccgtggtgcaggggcagggggaccgcctgggcgtgctccga gcactgttcttcagagttatcaaggactacccgtccaatgaagacctcccggagaggctg gaggtgttcaaggcgcttacagacaacgggcgacacatcacctacctggaagaggagctg gccgactttgtcctgcagtggatggacgtcggcctgtcctccgagttccttctggtgctt gtgaacttggtcaagttcaacagctgctacctggatgagcacattgcatctatggttcac atgatctgcctgctctgcgtccagactgtgtcccccgtggacatcgaggtgtccctgcag gtgttggacgccgtggtctgctacaactgcctgccggctgaaagcctcccactcttcctc gttaccctttgccggaccatcaatgtgaaggagctgtgtgagccctgctggaagctgatg cggaacctcctgggcacccacctgggccacagcgccatctgcaacatgtgccacatcatg gaggacagggcctacatggaggacgccccgctgctgagaggcgctgtgttcttcgtgggc atggccctgtggggcgcgcaccgcctctactcgctcaggaactccccggcatccgtgctg ccatccttctacgaggccatgacctgccccaatgagctcgtgtcctatgagatcgtcctc tccatcaccagactcaccaagaagtaccggcgggagttgcaggctgtgacctgggacatc ctgctgagcatcatggagcgcctgctccagcagctgcaggacctggacagcccggagctc aggaccatcgtgcacgacctgctgaccacggtggaggaactctgtgaccagaacgagttc cacggctcgcgcgagagatacttcgagctggtggagagatacgcgggccagaggcctgag tcctcactcctgaacctcatcacctaccgggcgcagtccatccaccccgcgaaggacggc tgggtccacagcctgcaagccctcatggacaggttcttcaggcaggagccccgcagtgct gtgcgcatcaaggtgctggacgtcctgtccttcgtgctgctcatcaaccggcagttctac gaggaggagctcatcagctctgtggtcatctcacagctgtgccacatccccgaggaccgg gatcaccaggtccgaaagctggccacccagctgctggtagacctggccgagggctgccac acacaccacttcaacagcctgttggacatcattgagaaggtgatggcacgcccgctctcc gcgccccccgagctggaggagagggacgtggccgcatactcggcgtccctggaggacgtg aagacggcggtgctggggctcctggtgatcttgcagacgaagctgtactgcctgccggcc agccacgccatgcgcgtgtacgacctgctcgtcggccacctgcagcagcactacaagtgc agctacaccctccccatcgccagtagcatccggctgcaggcctttgactttctgctgctg cttcgtgctgactcgctgcaccgcctgggcctgcccggcaaggacgggaccgtgcgcttc agtccctactgtctctgcgactccacggagccggacaggggctccgagaaggccagtggc cccctgtcgccgccctccgggccgccgggtgtgactcctgcaggccccgctgtgcgcctg ggctccctgccatatgcccggctcttccgggccctgctgcagtgcctgaagcaggagacg gactggaaggtgctgaaactggtgctgagccggctgcccgagtcactgcgctacaaggtc ctcgtcttcacgtctccgtgcagtgtggaccagctctccgcggcgctctgctccatgctt tcaggccccaagaccttggagcggcttcgcggcacccccgaaggcttctctaggaccgac ctccacctggccgtggtccctgtgctgaccgcgctcatctcttaccacgactacctggac aaggccagacagcgggagctcgtctactgcctggagcaaggcctcatcttccgctgtgcc agccagtgcgtggtagcactggccatctgcagcgtggagatgcctgacgtcatcatcaag gcgctgcccgtgctggtggtgaagctcactcacatctcggccacggccagcatggccgtc ccactgctcgagttcctgtccactctggccaggctgccgcacctttacaggaactttgcc gccgagcagtacgccagcgtgttcgccatctccctgccctacaccaacccctccaagttc aaccagtacatcgtgtgcctggcccaccacgtcatcgccatgtggttcatccgctgccgc ctgcccttccgcaaggactttgtcccctacatcactaagggcctgcggtccaacgtgctc ctgtcgttcgacgacaccccagagaaggacagcttcagggcgcggagcaccagcctcaat gagaggcccaagagtctgagggtagccaggccccccagacaaggcttgagccactctccg cccgtgaaagagctcccggagagctgcgccgccgaggccttccggtgccgcagtatcagt gtgtccgagcaggtggtccgcagcagaatccagacgtccctcaccagtgccagcctgggg tcggccgacgagaactccatggcccaggccgatgacaacctgaaaactctgcacctggag ctcacggagacgtgcctggacatgatggccagatatgtgttctccaacttcacggcagtg cccaagaggtcccccgtgggcgagttcctcctggccggtggcaggaccaagacctggctg gtggggaacaagctggtcacagtgaccaccagcgtgggtgccgggactcgctctctgctg ggcctggacgcgggagagcttcagggcagccctgagctgagccctggacccagcatgcaa gtgcggcagacgaaggaggcacctgccaagttggagtcccaggctgggcagcaggtgtgc cgaggggcccgcgaccgcgtccgctccatgtctgggggccacggccttcgcgtaggggcc ctggaggccccagccccccacttcccaggcagtcctgctcccgcgggaccgcagagcgcc cctgccgctgcccgccagcccgcgcagaaggagaggacgagcttggctgcctacgtgccg ctgctgacccaaggctgggcggagatcctggtgcgcaggcccacggggaacaccagctgg ctcatgagcctggagaacccgctgagccccttctcatccgacatcaccagcatgcccctg caggagctctccaacgccctcatggccgccgagcgcttcaaggagcggcgcgacacagcg ctctacaagtcactgtcggtgccggcagccggctcggccaagcccccacctccaccgcgg tccaacacggactcggctgtggtcctggaggagggtgggccagacgagagcatgctggcc gtagagccccctgggctggaggacctgggaatggcactgggcacggacgggcatgggcgc cattccacaccatttagccggtcgtcctccacgtccagccaggaggagaagtcgctgcgc ggggaggagcagagcgccagcgggatccccatggcacgggctgtgtcctccgagggcgcc cggccctctgctgacctctccttcgagccggcccagcctctcagcaagtccagctcctca cccgagctccagctgctgcaggacgtgcttgggggtcctggggacaaggctggcgggggc cgcctgagcccggaggccaaggcgcgctcccagtcagggaccctggacgggcccagcgcc ccctggctggcttcaggcagagagagccacggccctggacctgccgaggggccctcacct gccagctgcccccgctcccccagtggcctgcgaccccgtggctacaccatctccgactca gccccgtcccgcaggggcagacgggccgacagagactccttcaagggcagggccggggct ggcaacaccgagaaggtgccaggcatcaaccccagctttgtgttcctgcagctctaccac tctcctttctttggggacgagtccaacaagcccatccttctgccaaatgagtcattcgag cgctctgtgcaactcctggaccagataccctcctatgacacgcacaagatcgctgtcctg tatgtgggcgaaggccagagcaccaacgagctggccatcctgtccaatgaacacggctcc taccggtacaccgagttcctcatgggcttgggcaagctcattgagctcaaggactgccag ccggacaaggtctacttggggggcctggatgtgggtggcgaggatggccagttcacctac tgctggcatgacgacatcatgcaggccgtcttccacatcgccaccctgatgcccaccaag gacggggacaggcaccgttgtgacaagaagcgtcacctgggcaacgactttgtgtccatt gtgtacaacgactctggcgaggactttaagctgggcaccatccggggccagttcaacttc gtgcatgtgatcatcacccccctggactatgagtgtaacctggtgaccctgcagtgcaga aaagacatggagggcctcgtggacacgagcatggccaagatcgtgtctgaccggaacctg tccttcgtggcacgccagatggcactgcatgccaacatggcttcgcaggtgcaccacagc cgctcggaccccacggacatctacccctccaagtggatcaccagacttcgccacatcaag cggctccgccaccggctccgcgaggaagcacactcggccacccccggcctcccactgctg cagcccccgggccacgccaaggccccgacccccagcccggagcccccctacgagacaggc cagcggaagcgcctcatctcttccgtggacgatttcacggagttcgtgtaa

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