KEGG   Sorex fumeus (smoky shrew): 130044847
Entry
130044847         CDS       T10594                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum04010  MAPK signaling pathway
sfum04022  cGMP-PKG signaling pathway
sfum04137  Mitophagy - animal
sfum04141  Protein processing in endoplasmic reticulum
sfum04151  PI3K-Akt signaling pathway
sfum04210  Apoptosis
sfum04211  Longevity regulating pathway
sfum04261  Adrenergic signaling in cardiomyocytes
sfum04668  TNF signaling pathway
sfum04720  Long-term potentiation
sfum04722  Neurotrophin signaling pathway
sfum04725  Cholinergic synapse
sfum04728  Dopaminergic synapse
sfum04911  Insulin secretion
sfum04912  GnRH signaling pathway
sfum04915  Estrogen signaling pathway
sfum04918  Thyroid hormone synthesis
sfum04922  Glucagon signaling pathway
sfum04925  Aldosterone synthesis and secretion
sfum04926  Relaxin signaling pathway
sfum04927  Cortisol synthesis and secretion
sfum04928  Parathyroid hormone synthesis, secretion and action
sfum04932  Non-alcoholic fatty liver disease
sfum04934  Cushing syndrome
sfum04935  Growth hormone synthesis, secretion and action
sfum05010  Alzheimer disease
sfum05012  Parkinson disease
sfum05014  Amyotrophic lateral sclerosis
sfum05020  Prion disease
sfum05022  Pathways of neurodegeneration - multiple diseases
sfum05030  Cocaine addiction
sfum05031  Amphetamine addiction
sfum05034  Alcoholism
sfum05161  Hepatitis B
sfum05163  Human cytomegalovirus infection
sfum05166  Human T-cell leukemia virus 1 infection
sfum05203  Viral carcinogenesis
sfum05207  Chemical carcinogenesis - receptor activation
sfum05215  Prostate cancer
sfum05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    130044847 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    130044847 (ATF4)
   04668 TNF signaling pathway
    130044847 (ATF4)
   04022 cGMP-PKG signaling pathway
    130044847 (ATF4)
   04151 PI3K-Akt signaling pathway
    130044847 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    130044847 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    130044847 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    130044847 (ATF4)
   04922 Glucagon signaling pathway
    130044847 (ATF4)
   04912 GnRH signaling pathway
    130044847 (ATF4)
   04915 Estrogen signaling pathway
    130044847 (ATF4)
   04926 Relaxin signaling pathway
    130044847 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    130044847 (ATF4)
   04918 Thyroid hormone synthesis
    130044847 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    130044847 (ATF4)
   04925 Aldosterone synthesis and secretion
    130044847 (ATF4)
   04927 Cortisol synthesis and secretion
    130044847 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    130044847 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    130044847 (ATF4)
   04728 Dopaminergic synapse
    130044847 (ATF4)
   04720 Long-term potentiation
    130044847 (ATF4)
   04722 Neurotrophin signaling pathway
    130044847 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    130044847 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    130044847 (ATF4)
   05203 Viral carcinogenesis
    130044847 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    130044847 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    130044847 (ATF4)
   05161 Hepatitis B
    130044847 (ATF4)
   05163 Human cytomegalovirus infection
    130044847 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    130044847 (ATF4)
   05012 Parkinson disease
    130044847 (ATF4)
   05014 Amyotrophic lateral sclerosis
    130044847 (ATF4)
   05020 Prion disease
    130044847 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    130044847 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    130044847 (ATF4)
   05031 Amphetamine addiction
    130044847 (ATF4)
   05034 Alcoholism
    130044847 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    130044847 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    130044847 (ATF4)
   04934 Cushing syndrome
    130044847 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:sfum03000]
    130044847 (ATF4)
Transcription factors [BR:sfum03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    130044847 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 ZapB DUF4407 Asd-4 DUF3450 OVT1 Nop53 AAA_13
Other DBs
NCBI-GeneID: 130044847
NCBI-ProteinID: XP_055993478
LinkDB
Position
Unknown
AA seq 344 aa
MAEMSFLGSEVLGGDLMSPFDPSGLGAEEGLGLLDDYLEVAKHFRPHGLSGDKARAGCSE
WLAVDGGKEDAFSGTDWMVEKMDLKEFDFDSLLNLGDLDMPDELLATLDTGGLFDPLQES
DKEPPQVENPIGHLPESSPKADQVAPFTFLQPLPPSPGPLPSTPDHAFSLELGSEVVIAA
GDRKPDAAAPATAISLCIKEEDAPSDNDSGVCMSPDSYLGSPQHSPPATRGSPSRGLLSS
PGALCGGPARPKPYDPPGERMVAAKLKGEKLDKKLKKMEQNKTAATRYRQKKRAEQEALT
GECRELEKKNEALKERADSLAKEIQYLKDLMEEVRRARGKKRVP
NT seq 1035 nt   +upstreamnt  +downstreamnt
atggccgagatgagcttcctgggcagcgaggtgttggggggggacttgatgtcccccttc
gacccgtcgggtttgggggctgaagagggcctcggcctcctggacgactacctggaggtg
gccaagcacttcagaccccatgggctctccggcgacaaggctagggcgggctgctccgag
tggctggcggtggacggcggcaaggaagatgccttctcgggcacagactggatggtggag
aagatggatctgaaggagtttgacttcgacagcctgctgaatctcggcgacctggacatg
cccgacgagctcttagccacgctggacaccggcggcctctttgacccactccaggagagt
gacaaggagcccccccaggtcgagaaccccattggccatcttccagaaagttccccgaaa
gcagaccaggttgcccccttcaccttcctgcagccgctgcccccctctcccggcccgctg
ccctccactccagaccacgcctttagcttagagctgggcagcgaggtggtgatcgctgcc
ggggacaggaagcccgatgccgcggcccccgccactgccatctctctgtgcataaaggag
gaagatgccccctcagacaacgacagcggcgtctgcatgagccccgactcctacctgggc
tccccccagcatagcccccctgccaccaggggctcgcccagtaggggcctgctctcctcc
ccaggtgccctctgtggtggccctgcccgccccaagccctacgaccctcctggggagagg
atggtggcagcaaagctcaagggcgagaagctagacaagaagctgaagaagatggagcag
aacaagacggcagccaccaggtaccgccagaagaagcgggcggagcaggaggccctgacg
ggcgagtgcagagagctggagaagaagaacgaggctctgaaagagcgcgccgactccctg
gccaaggagatccagtacctgaaagacctgatggaggaggtccgcagggccaggggcaag
aagcgggtgccctag

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