Sorex fumeus (smoky shrew): 130045210
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Entry
130045210 CDS
T10594
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1 isoform X1
KO
K12385
Niemann-Pick C1 protein
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
sfum04142
Lysosome
sfum04979
Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
130045210 (NPC1)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
130045210 (NPC1)
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
130045210 (NPC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
sfum02000
]
130045210 (NPC1)
Transporters [BR:
sfum02000
]
Solute carrier family (SLC)
SLC65: NPC-type cholesterol transporter
130045210 (NPC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NPC1_MLD
NPC1_N
Sterol-sensing
Patched
MMPL
Motif
Other DBs
NCBI-GeneID:
130045210
NCBI-ProteinID:
XP_055993908
LinkDB
All DBs
Position
Unknown
AA seq
1294 aa
AA seq
DB search
MSARGRTVGLLLLLSVAQVRAQACVWYGECGIASGDKRYNCEYSGPPKPLPKDGYDLVQE
LCPGFFFNDVSLCCDVRQLQTLKENLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQFL
NVTATGDYVDPVTNQTKTNVIELQYYIGESFANAMYNACRDVEAPSSNDKALGLLCGKEA
EACNATNWIEYMFNKDNGQAPFTITPVFSDLSIHGMEPMNNATKGCDQPVDEVTAPCSCQ
DCSVVCGPKPQPPPMPPPWRILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSE
YTPIDSNIAFSVNASDKGMAWLLTSTLPSSPALPGEASCCDPLGAAFEGCLKQLFTQWGS
FCVRNPGVVLFFSLAFIGACSSGLVFVRITTNPVELWSAPSSQARQEKQYFDTHFGPFFR
TEQLIIRAPNTKTHTYEPYPSGSDVPFGPPLDKEILHQVLELQTAIENITATYNNKTVTL
QDICLTPLSPYNRNCTILSVLNYFQNSHAMLDRKIEDDFYVYADYHTHFLYCVRAPASLN
DTSVLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVMTFPVNNYYNDTEKLRRTEAWE
REFINFVRNYKHPNLTISFTAERSIEDELNRESQSDVYTVVISYAIMFLYISIALGHIKS
CRRLLVDSKISLGIAGILIVLSSVACSLGIFSFLGIPLTLIVIEVIPFLVLAVGVDNIFI
LVQTYQRDERLQGESLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFA
GMAVFIDFLLQISCFVSLLGLDIKRQEKGRLDILCCTSIADDDGTSVQASESFLFRFFRK
SYAPFLLKDWMRPIVIAVFVGILSFSVAVLNKVEIGLDQALSMPDDSYVVDYFKSLSQYL
HAGPPVYFVVQEGHNYTSLKGQNMVCGGMGCDNDSLVQQIFNAAQMDNYTRIGFAPSSWI
DDYFDWIKPQSSCCRVYNNTEQFCNASVVDPACLRCRPLTQEGKQRPQGGDFMRFLPMFL
SDNPNPKCGKGGHAAYGSAVNILGNDTSVGATYFMTYHTVLQTSADFIDAMTKARLIAAN
ITRTMGLEESHYRVFPYSVFYVFYEQYLTIVDDTIFNLSVSLGAIFLVTMVLLGCELWAA
VIMCSTIAMILINMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSARGSRV
ERAEEALSHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFL
PVLLSYIGPSVNKAKSLSTRERYKGTEREHLLNF
NT seq
3885 nt
NT seq
+upstream
nt +downstream
nt
atgagcgctcgcgggcgcacggtcggcctcctgctgctgctgtctgtggcgcaggtgcgt
gcacaggcttgtgtgtggtatggagagtgtggaattgcatctggagacaagaggtacaat
tgtgaatattctgggccaccaaaaccactgccaaaggatggatatgacttagtacaggaa
ctgtgtcccggattcttttttaacgatgtcagtctttgttgtgatgttcggcagcttcag
acactgaaagaaaacctgcagctccctctgcagttcctgtccagatgtccttcctgcttt
tataacctcatgaacctattttgtgagctgacatgtagccctcgacagagtcagtttcta
aatgttactgcaactggagattatgttgatcctgttacaaaccaaacaaagacgaacgtg
atagagctgcagtactatatcggagagagtttcgccaatgccatgtacaatgcctgccgg
gatgtggaggccccctcaagcaatgacaaggccctggggcttctgtgtgggaaggaggct
gaagcctgcaacgccaccaactggattgagtacatgttcaacaaggacaatgggcaggcg
cccttcaccatcacgcccgtcttctcagacctttcgatccacggaatggagcccatgaac
aatgccaccaaaggctgcgaccagcctgtggatgaggtcacggcaccgtgcagctgccag
gactgctcagtcgtttgtggcccgaagccccagcccccacccatgcctcctccctggaga
atcttgggcctggatgccatgtatgtcatcatgtggatcacctacatggcatttttgctt
gtgttttttggagcgttttttgctgtgtggtgctacaggaaacgctattttgtctctgag
tacacccctatcgacagcaacatcgcattctccgtaaacgccagcgacaaaggaatggct
tggctcttaacctccaccctcccttcctctcccgcccttccaggggaggcgtcctgctgt
gaccccctgggcgcggccttcgagggctgtctgaagcagctcttcacccagtggggctcc
ttctgtgtccgcaaccccggtgtcgtcctcttcttctccctggccttcatcggggcgtgc
tcttcgggcctggtgtttgtgcgcatcaccaccaacccggtggagctgtggtctgccccc
agcagccaggcccgccaggagaaacagtactttgacacgcactttgggccattcttccgc
acggagcagctcatcatccgggcccccaacaccaagacgcacacttacgagccgtatccc
tcgggatccgacgtgccctttgggcctccgctggacaaagagattttgcaccaggtgctt
gagctgcagacagccattgaaaacattactgccacctacaacaacaagacggtgacgctt
caggatatctgcctgacccctctctccccgtataaccggaactgcaccatcctgagcgtg
ctgaactacttccagaacagtcatgccatgctggaccgcaagatagaggatgacttctac
gtgtacgccgactatcacacgcacttcctgtactgtgtccgggctcctgcctctctgaac
gacacgagtgtgctccacgatccttgtctggggacgttcggcgggccggtgttcccctgg
cttgtcctgggaggctacgatgatcaaaactacaataatgctacagcccttgtgatgacc
tttcctgtcaataattactataatgatacagagaagctccggagaactgaggcctgggaa
agagagttcattaattttgtgagaaactacaagcatccgaacctgaccatttctttcact
gctgaacggagcattgaagatgagctcaatcgcgagagccaaagcgacgtctacaccgtg
gtgatcagctacgccatcatgtttttgtacatctccatagcactgggccacatcaagagc
tgcaggcggctgctggtggattctaagatctccctgggcatcgcgggcatcctcattgtc
ctgagctccgtcgcctgctctctgggcatcttcagtttcctggggatccccctcaccctc
attgtgatcgaagtgatcccgtttctggtactggccgttggggtggacaacatcttcatt
ctggtccagacctaccagagagacgaacgccttcaaggagaaagtctggaccagcagctg
ggcagggtcctgggagaggtggcccccagcatgttcctgtcttccttctcagagacggtc
gcctttttcttaggggccctgtcggtgatgccggccgtgcacaccttctcgctgttcgcc
ggcatggcggtcttcatcgacttcctcctgcagatcagctgcttcgtgagtctcctgggc
ttagacattaagcgtcaggagaaaggccgcctggacatcctctgctgcaccagcattgcc
gatgacgacggcacaagcgtgcaggcctcggagagcttcttgtttcggttcttcagaaag
tcctatgccccgtttctgctcaaggactggatgcggcccattgtgatcgcggtgtttgtg
ggcattctgtccttcagcgtcgccgtcctgaacaaagtagagatcggactggaccaggcg
ctctccatgccagatgactcctacgtggtggattacttcaagtcgctcagtcagtacctg
cacgcaggcccacctgtctacttcgtcgtgcaggaagggcacaactacacctccctgaag
gggcagaacatggtgtgcgggggcatgggctgtgacaacgactccctggtgcagcagata
ttcaacgcagcacagatggacaactacacccgcataggctttgccccctcgtcctggatc
gatgattattttgactggattaaaccacagtcgtcttgctgccgcgtctacaacaacacc
gagcagttctgcaacgcctcagtggtggacccggcctgcctgcgctgcagacctctgacc
caggagggcaagcagagaccccagggaggagacttcatgaggttcctgcccatgttcctt
tccgacaaccccaaccccaagtgcggcaaagggggccacgcggcttatggttcggcagtg
aacatccttggcaacgacaccagcgttggagccacctacttcatgacgtaccacacagtt
ctccagacctctgctgacttcattgatgccatgaccaaggcccgcctcatcgctgctaac
atcaccaggaccatgggcctggaagagagtcattaccgtgtgttcccgtacagtgtgttc
tatgtcttctacgagcagtacctgaccatcgtggatgacaccatctttaacctcagcgtg
tccctgggtgccatcttcttggtgaccatggttctcctgggctgcgagctgtgggccgcc
gtcatcatgtgcagcaccatcgccatgatcctcatcaacatgtttggtgttatgtggctg
tggggcatcagcctcaatgctgtgtccctggtcaacctggtgatgagttgtggcatctcc
gtggagttctgcagccacatcaccagagcattcaccgtgagcgcgagaggcagccgtgtg
gagcgggcagaagaggcgctctcccacatgggcagctccgtattcagtggaatcacacta
acaaaatttggaggaattgtagtattagcttttgccaaatctcagattttccagatattt
tacttcaggatgtatttagcaatggtcttgcttggagccactcatggactaattttcctg
cccgtcttactcagttatataggaccttctgtaaataaagccaaaagtctgtccactcgg
gaacgatacaaagggacagagcgagaacatctcctgaacttctag
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