Sorex fumeus (smoky shrew): 130045805
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Entry
130045805 CDS
T10594
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum03060
Protein export
sfum04141
Protein processing in endoplasmic reticulum
sfum04612
Antigen processing and presentation
sfum04918
Thyroid hormone synthesis
sfum05012
Parkinson disease
sfum05014
Amyotrophic lateral sclerosis
sfum05020
Prion disease
sfum05022
Pathways of neurodegeneration - multiple diseases
sfum05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
130045805 (HSPA5)
04141 Protein processing in endoplasmic reticulum
130045805 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
130045805 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
130045805 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
130045805 (HSPA5)
05014 Amyotrophic lateral sclerosis
130045805 (HSPA5)
05020 Prion disease
130045805 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
130045805 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
130045805 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
sfum03110
]
130045805 (HSPA5)
04131 Membrane trafficking [BR:
sfum04131
]
130045805 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
sfum04147
]
130045805 (HSPA5)
Enzymes [BR:
sfum01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
130045805 (HSPA5)
Chaperones and folding catalysts [BR:
sfum03110
]
Heat shock proteins
HSP70 / DNAK
130045805 (HSPA5)
Membrane trafficking [BR:
sfum04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
130045805 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
130045805 (HSPA5)
Exosome [BR:
sfum04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
130045805 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
130045805 (HSPA5)
Exosomal proteins of colorectal cancer cells
130045805 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
130045805
NCBI-ProteinID:
XP_055994661
LinkDB
All DBs
Position
Unknown
AA seq
654 aa
AA seq
DB search
MKLSVVAAVLLLLGSARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKRLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPTEKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctctccgtggtggccgcggtgctgctgctgctcggctcagcgcgggccgaggag
gaggacaagaaggaggacgtgggcacggtggtcggcatcgacctggggaccacctactcc
tgcgtcggggtcttcaagaacggccgcgtggagatcatcgccaacgaccagggcaaccgc
atcacgccctcctatgtggccttcacccccgagggggagcggctgatcggcgacgccgcc
aagaaccagctcacctccaaccccgagaacacggtcttcgacgccaagcggctcatcggc
cgcacgtggaacgacccgtctgtgcagcaggacattaagttcttgccgttcaaggtggtt
gaaaagaaaactaaaccatatatccaagttgatattggaggtgggcagacaaagacattt
gctcctgaagaaatttctgccatggttctcacaaaaatgaaggaaacagctgaagcttac
ttgggaaagaaggttacccatgcggtggttactgtaccagcctatttcaatgatgctcag
cgccaggcaaccaaagatgctggaaccattgctggattgaatgttatgaggatcatcaat
gaaccaacagcagctgctattgcttatggcctggataagagggaaggagagaagaacatc
ctggtgtttgaccttggtgggggaaccttcgatgtgtctcttcttaccattgataatggt
gtctttgaagttgtggccactaatggagatactcacttgggtggagaagactttgaccag
cgtgtgatggaacactttatcaagctctacaaaaagaagacgggcaaagacgttcggaaa
gacaacagagctgtgcagaaactccggcgtgaggtagaaaaggccaagcgtgccctgtct
tctcagcatcaagcaagaatcgaaattgagtccttctttgaaggagaagacttctctgag
accctgactcgggccaaatttgaagagctaaacatggacctgttccgttctaccatgaaa
cctgtccagaaagtgctggaagattcggatttaaagaagtctgatattgatgaaattgtt
cttgttggtggctctactcgaatcccaaagattcaacagctggttaaagagttcttcaat
ggcaaggaaccatcccgtggcataaacccagatgaggctgttgcttatggtgctgctgtc
caggctggtgtcctctctggtgatcaggatacaggggatctggttttgcttgatgtgtgt
ccccttacccttggtattgaaactgtgggaggtgtcatgacaaagctgattccaaggaac
actgtggtgcccaccaagaagtctcagatcttttctacagcttctgataatcagccaact
gttacaatcaaggtctatgaaggtgaacgacctctgacaaaagacaatcaccttctggga
acttttgatctgactggaattcctcctgctccccgtggggtgccacagattgaagtcacc
tttgagatagatgtaaatggcattcttcgagtgacagctgaagacaaaggcacagggaac
aaaaataagatcacaatcactaatgaccagaataggctgacacctgaagaaattgaaagg
atggttaatgatgctgagaagtttgctgaggaagacaaaaggctcaaggagcgcattgat
acaagaaatgaattggaaagctatgcctactcactaaagaatcaaattggagataaagaa
aagctggggggtaagctttcctctgaagacaaggaaaccatggaaaaagccgtagaggaa
aagattgaatggctggaaagtcaccaagatgctgacattgaagatttcaaagctaaaaag
aaggaactggaagaaattgttcagccaattatcagcaaactctatggaagcgcaggccct
cccccaaccggtgatgaggaaccaacagaaaaagatgagttgtag
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