Sorex fumeus (smoky shrew): 130045964
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Entry
130045964 CDS
T10594
Symbol
ATP2A1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum04020
Calcium signaling pathway
sfum04022
cGMP-PKG signaling pathway
sfum04024
cAMP signaling pathway
sfum04148
Efferocytosis
sfum04260
Cardiac muscle contraction
sfum04261
Adrenergic signaling in cardiomyocytes
sfum04380
Osteoclast differentiation
sfum04919
Thyroid hormone signaling pathway
sfum04972
Pancreatic secretion
sfum05010
Alzheimer disease
sfum05017
Spinocerebellar ataxia
sfum05022
Pathways of neurodegeneration - multiple diseases
sfum05410
Hypertrophic cardiomyopathy
sfum05412
Arrhythmogenic right ventricular cardiomyopathy
sfum05414
Dilated cardiomyopathy
sfum05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
130045964 (ATP2A1)
04024 cAMP signaling pathway
130045964 (ATP2A1)
04022 cGMP-PKG signaling pathway
130045964 (ATP2A1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
130045964 (ATP2A1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
130045964 (ATP2A1)
09153 Circulatory system
04260 Cardiac muscle contraction
130045964 (ATP2A1)
04261 Adrenergic signaling in cardiomyocytes
130045964 (ATP2A1)
09154 Digestive system
04972 Pancreatic secretion
130045964 (ATP2A1)
09158 Development and regeneration
04380 Osteoclast differentiation
130045964 (ATP2A1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
130045964 (ATP2A1)
05017 Spinocerebellar ataxia
130045964 (ATP2A1)
05022 Pathways of neurodegeneration - multiple diseases
130045964 (ATP2A1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
130045964 (ATP2A1)
05412 Arrhythmogenic right ventricular cardiomyopathy
130045964 (ATP2A1)
05414 Dilated cardiomyopathy
130045964 (ATP2A1)
05415 Diabetic cardiomyopathy
130045964 (ATP2A1)
Enzymes [BR:
sfum01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
130045964 (ATP2A1)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
CA109-like
Motif
Other DBs
NCBI-GeneID:
130045964
NCBI-ProteinID:
XP_055994829
LinkDB
All DBs
Position
Unknown
AA seq
1001 aa
AA seq
DB search
MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGPNELPAEEGKSLWELVVEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVEGDSCVLNEFSITGSTYAPEGEVMKNDKPVRAGQYDGLVELATICALC
NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTEVRSLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSSRTVVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGP
AKDKIMSVIKEWGTGRDTLRCLALATRDTPPKREELILDDSARFMEYETDLTFVGVVGML
DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVTDRAYTGREFDD
LPLGEQRDACRRACCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI
GGYVGAATVGAAAWWFLYAEDGPHVSYNQLTHFMQCNEENPEFEGLDCEIFEAPEPMTMA
LSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR
ALDMNQWIMVLKISLPVIGLDELLKFIARNYLEDPEDERRK
NT seq
3006 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggcacactccaagtccacagaggaatgcctggcctattttggggtgagcgag
accacaggtctcaccccggaccaagtcaagcggcatctggagaaatacggccccaatgag
ctgcccgcggaggaaggcaagtccctgtgggagctggtggtggagcagttcgaggacctg
ctggtgcgcatccttctcctggccgcctgcatctcctttgtgctggcctggtttgaggaa
ggcgaagagaccatcacggccttcgtggagccctttgtcatcctgctgatcctcatcgcc
aacgccatcgtcggggtctggcaggagcggaacgcggagaacgccatcgaggcgctgaag
gagtatgagcctgagatggggaaggtgtaccgggctgaccgcaagtccgtgcagaggatc
aaggcgcgggacattgtccctggggacatcgtggaggtggctgtgggggacaaagtccct
gctgacatccggatcctgtccatcaagtccaccaccctccgcgtggaccagtccatcctg
acaggtgagtctgtctctgtcatcaagcacacagaccccgtccccgacccccgcgccgtc
aaccaggacaagaagaacatgctcttctcgggcaccaacatcgcagccggcaaggccttg
ggcattgtggccaccacgggcgtgagcaccgagatcggcaagatccgtgaccagatggcc
gccacggagcaggacaagacccctctgcagcagaagctggacgagtttggcgagcagctg
tccaaggtcatctccctcatctgcgtggccgtctggctcatcaacatcggccacttcaac
gaccctgtgcatgggggctcctggttccgaggcgccatctactactttaagattgccgtg
gccctggctgtggctgcgatcccggaaggtcttcctgccgtcatcaccacctgcctggcc
ttgggtacccgccggatggcgaagaagaatgccattgtcaggagcttgccctccgtcgag
actctgggctgcacctccgtcatctgctcggacaagacgggcaccctcaccaccaaccag
atgtctgtgtgcaagatgttcatcatcgacaaggtggaaggtgactcctgtgtcctgaac
gagttttccatcacgggctcaacatacgctcccgaaggagaggtcatgaagaatgataag
ccagtccgggcagggcagtatgacgggctggtggagctggccaccatctgtgccctctgc
aatgactcttccctggacttcaatgaggccaaaggtgtctatgagaaggtgggtgaggcc
accgagacggccctcaccaccctggtggagaagatgaacgtcttcaacacggaagtgagg
agcctgtccaaggtggagcgagccaacgcgtgcaactcagtgatccgccagctgatgaag
aaggaattcaccctggagttttcccgtgaccgcaaatccatgtctgtctactgctcccct
gccaagtcctcccggaccgttgtgggcaacaagatgtttgtcaagggtgcccccgagggg
gtcattgaccgctgcaactacgtgagggtcggcaccacccgtgtgcccatgacggggcct
gcaaaggacaagatcatgtctgtgatcaaggagtgggggaccggccgcgacactctgcgc
tgtctggcccttgccactcgggacacccccccaaagcgtgaggagctgattctggatgac
tctgcccgcttcatggagtacgagacggacctgaccttcgtgggcgtggtggggatgctg
gacccgccccgcaaagaggtgaccggctccatccagctgtgccgcgacgccggcatccgg
gtgatcatgatcaccggagacaacaagggcacggccatcgccatctgccggcgcattggc
atcttcggggagaacgaggaggtgacagaccgtgcctacacgggccgtgagttcgacgac
ctgcccctgggggagcagcgggacgcctgccgccgcgcctgctgcttcgcccgcgtggag
ccctcgcacaagtccaagatcgtggagttcctgcagtccttcgacgagatcacggccatg
accggagacggcgtcaatgatgcccccgccctgaagaaggccgagatcggcattgccatg
ggctcgggcaccgccgtggccaagacggcctctgagatggtgctggcagacgacaatttc
tccaccatcgtggcggccgtggaggagggccgcgccatctacaacaacatgaagcagttc
atccgctacctcatctcctccaacgtgggcgaggtggtgtgcatcttcctgacagccgcc
ctggggctgcccgaggccctgatcccagtgcagctgctgtgggtgaacctggtgaccgat
gggctcccggccacagccctgggcttcaacccccccgacctggacatcatggaccgcccc
ccccggagccccaaggagcccctcatcagtggctggctcttcttccgctacatggccatt
gggggctatgtgggggcagccacagtcggggcagccgcctggtggttcttgtacgccgag
gatgggccacacgtctcctacaaccagctgactcacttcatgcagtgcaacgaggaaaac
cccgaattcgagggtctggactgtgagatctttgaggcccctgagcccatgacgatggcc
ttgtctgtactggtcaccattgagatgtgcaatgctctcaacagcctgtcagagaaccag
tccctcatgaggatgccaccctgggtgaacatctggctgctgggctccatctgcctctcc
atgtcccttcacttcctcatcctctacgtcgaccctctgcccatgatcttcaagctccgg
gccctggacatgaaccagtggatcatggttctcaagatctccttgccagtcatcgggctg
gacgaactcctcaagttcattgcccggaactatcttgaggatccagaagacgagagaagg
aagtga
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