Sorex fumeus (smoky shrew): 130046117
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Entry
130046117 CDS
T10594
Symbol
VAV3
Name
(RefSeq) guanine nucleotide exchange factor VAV3 isoform X1
KO
K05730
guanine nucleotide exchange factor VAV
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum04015
Rap1 signaling pathway
sfum04024
cAMP signaling pathway
sfum04062
Chemokine signaling pathway
sfum04510
Focal adhesion
sfum04650
Natural killer cell mediated cytotoxicity
sfum04660
T cell receptor signaling pathway
sfum04662
B cell receptor signaling pathway
sfum04664
Fc epsilon RI signaling pathway
sfum04666
Fc gamma R-mediated phagocytosis
sfum04670
Leukocyte transendothelial migration
sfum04810
Regulation of actin cytoskeleton
sfum05135
Yersinia infection
sfum05205
Proteoglycans in cancer
sfum05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
130046117 (VAV3)
04024 cAMP signaling pathway
130046117 (VAV3)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
130046117 (VAV3)
09142 Cell motility
04810 Regulation of actin cytoskeleton
130046117 (VAV3)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
130046117 (VAV3)
04660 T cell receptor signaling pathway
130046117 (VAV3)
04662 B cell receptor signaling pathway
130046117 (VAV3)
04664 Fc epsilon RI signaling pathway
130046117 (VAV3)
04666 Fc gamma R-mediated phagocytosis
130046117 (VAV3)
04670 Leukocyte transendothelial migration
130046117 (VAV3)
04062 Chemokine signaling pathway
130046117 (VAV3)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
130046117 (VAV3)
09171 Infectious disease: bacterial
05135 Yersinia infection
130046117 (VAV3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
130046117 (VAV3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RhoGEF
SH3_2
CAMSAP_CH
CH
SH2
SH3_9
SH3_1
SOS1_NGEF_PH
C1_1
PH
RHG20_PH
CDC24
Filamin
LZ3wCH
PH_10
Prok-RING_1
SH2_1
C1_2
zf-RING_16
zf-RING-like
Motif
Other DBs
NCBI-GeneID:
130046117
NCBI-ProteinID:
XP_055994989
LinkDB
All DBs
Position
Unknown
AA seq
875 aa
AA seq
DB search
MEPWRQCAQWLIHCKVLPANHRVTWDSAQVFDLAQTLRDGVLLCQLLNNLRAHSINLKEI
NLRPQMSQFLCLKNIRTFLTACCETFGMRKSELFEAFDLFDVRDFGKVIETLSRLSRTPI
ALATGIRPFPTEESINDEDIYKGLPDLIDETHVEDEEGLYDCVYGEDEGGEVYEDLMKAE
ETHQPKCPENDIRSCCLAEIKQTEEKYTETLESIEKYFMAPLKRFLTAKEFDSVFINIPE
LVKVHRSLMQEIHDSITNKNDQNLYQVFINYKERLVIYGQYCSGVELAISSLDYISKTKE
DVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTTDPLEKSNLKLALDA
MKDLAQYVNEVKRDNETLREIKQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQER
HIFLFDLAVIVCKRKGDNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGQNGL
EFYCKTKDLKKKWLEQFEMALSNIRPDYADSNFHEFKMHTFNRVTSCKVCQMLLRGTFYQ
GYLCFKCGARAHKECLGRVDSCGRVNSAEQGTIKPLEKRTNGLGRTSRQVDPGLPKMQAI
RNYSGTPPPALHEGPPLHIQAGDTVELLRGDAHSLFWQGRNLASGEVGFFPSDAVKPCPC
VPKPVDYSCQPWYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIK
ILTRDGFFHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEHSAGQRANRG
GSSSPSLFCGFSLVTPPDYSFVPPSSTPFWSVLSPKVLGIAIARYDFCARDMRELSLLKG
DVVKIYTKMSANGWWRGEVNGRVGWFPSTYVEEDE
NT seq
2628 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtggcggcagtgcgcgcagtggctcatccactgcaaggtgctgcccgccaac
caccgggtgacctgggactcggcgcaggtgttcgacctggcgcagaccctccgcgatggg
gtcctgctctgccagctgctcaacaacctccgggcgcactccatcaacctcaaggagatc
aacctgaggccgcagatgtcccagttcctctgtttgaagaatataaggactttccttacg
gcctgttgtgagacatttggaatgagaaagagtgaactctttgaggcctttgacctgttt
gatgttcgtgactttggaaaggttatagaaactttatcacgactctctcgcacacctata
gcactggccacaggaatcaggcccttcccaaccgaagaaagcatcaacgatgaggacatc
tacaaaggcctacctgatttaatagatgaaacccatgtagaagatgaggaggggctctat
gactgtgtatacggggaagatgaaggcggggaagtgtacgaggacttgatgaaagctgag
gaaacgcatcaacctaaatgtccagaaaatgatatacgaagttgctgcttagctgaaatt
aagcagacagaagaaaaatacacagaaactttggagtcaatagaaaaatatttcatggct
ccactaaaaagatttctgacggcaaaagaatttgattcagtattcatcaacattcctgaa
cttgtcaaagttcatcggagccttatgcaggagatccatgattccattacaaataaaaat
gatcagaacttgtatcaagttttcattaactacaaggaaaggttggttatttatggacag
tactgcagtggagtggaattagccatctctagtttagactacatttctaagacgaaagaa
gatgtcaaactgaaattagaggaatgttccaaaagagcaaataatgggaagtttactctt
cgagacttgcttgtggttccaatgcagcgtgtgttaaagtatcaccttctcctccaggaa
ctggtcaaacacaccaccgatcctttggagaagtcaaacctgaaactggctctcgatgca
atgaaggacttggcacaatatgtgaatgaagtgaaaagagataatgagacccttcgtgaa
attaaacagtttcagctatctatagaaaatttgaaccaacctgttttgctgtttggaaga
ccccagggagatggtgaaattcgaatcactactcttgacaaacataccaaacaagaaagg
catatcttcttatttgatttggcagtaattgtctgtaaaagaaaaggtgataactatgaa
atgaaggaaataatagatcttcagcagtataaaatagccaacaaccctacgactgataaa
gaaaataagaagtggtcttatggcttctacctcatccatacccaaggacaaaacggttta
gaattttattgcaaaacaaaggatttaaagaaaaaatggctggagcaatttgaaatggct
ttatctaacataagaccagactatgcagactccaattttcatgagttcaagatgcatacc
ttcaacagagttacatcctgtaaagtctgccagatgctcctcagaggaacattttatcaa
ggctatttatgttttaagtgtggtgcaagagcacacaaggaatgcttgggaagagtagac
agctgtggcagagttaactctgctgaacaagggacgatcaaaccactggagaaacgaacc
aatgggcttggaagaacctccagacaggtggacccagggttaccaaagatgcaggctatt
agaaactactccggaacaccacccccagctcttcatgaaggaccccccttacacatccag
gcgggagacacagttgaacttctccgaggagatgcgcacagtttgttttggcagggtaga
aacttagcatctggagaggttggatttttcccaagtgatgctgtcaagccttgcccatgt
gtgcccaaaccagtagattattcttgccaaccctggtatgctggagcaatggaaagattg
caagcagaaactgaacttattaatagggtaaatagtacttacctggtgaggcacaggacc
aaagagtcaggagaatatgcaattagcattaagtacaataatgaagcaaagcacatcaag
attttaacaagagatggcttctttcacattgcagaaaatagaaaatttaaaagtttaatg
gaacttgtggagtactacaagcatcattctctcaaagaaggattcagaaccttagacacg
actctgcagtttccgtacaaggagcctgaacattcagcaggacagagggctaatcgagga
ggcagcagctccccttctttgttctgtgggttttctcttgtcactcctccagactacagc
tttgttcccccttcttccactcctttctggtcagtgctgagtcccaaagtgctggggatt
gccattgcacgttatgacttctgtgcgcgggacatgcgggaactgtccttgttgaaaggg
gacgtggtgaagatctacacgaagatgagcgcgaatggctggtggagaggagaagtcaat
ggccgggtgggctggtttccatccacctatgtggaagaggatgaataa
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