Sorex fumeus (smoky shrew): 130046171
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Entry
130046171 CDS
T10594
Symbol
DPYD
Name
(RefSeq) dihydropyrimidine dehydrogenase [NADP(+)]
KO
K00207
dihydropyrimidine dehydrogenase (NADP+) [EC:
1.3.1.2
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum00240
Pyrimidine metabolism
sfum00410
beta-Alanine metabolism
sfum00770
Pantothenate and CoA biosynthesis
sfum00983
Drug metabolism - other enzymes
sfum01100
Metabolic pathways
Module
sfum_M00046
Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
Brite
Enzymes [BR:
sfum01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
130046171 (DPYD)
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Other DBs
NCBI-GeneID:
130046171
NCBI-ProteinID:
XP_055995062
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Position
Unknown
AA seq
1025 aa
AA seq
DB search
MAPVLSKDAADIESILALNPRTQTHATLRSTSAKKLDKKHWKRNPDKNCFNCEKLENNFD
DIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLAIKSFITSIANKNYYGAAKMIFSDN
PLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMNIPQIRNPSLPPPE
KMPEAYSTKIALFGAGPASISCASFLARLGYSDITIFEKQEYAGGLSISEIPQFRLPYDV
VNFEIELMKDLGVKIICGKSLSVNEMTLSTLKEEGYKAAFIGIGLPEPNKDSIFEGLTQD
QGFYTSKDFLPLVAKSSKAGMCACHSPLPSIQGAVIVLGAGDTAFDCATSALRCGARRVF
VVFRKGFVNIRAVPEEMELAKEEKCEFLPFLSPRKVIVKGGRIVAMQFVRTEQDETGTWK
EDEDQIVHLKADVVISAFGSILSDPKVKEALNPLKFNRWGLPEVDPETMQTSEPWVFAGG
DIVGMANTTVESVNDGKQASWYIHKYIQSQHGASVSSQPELPLFYTPIDLVDISVEMAGL
KFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIRGTTSGPMY
GPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCTYNKNDWMELSKKAEAS
GADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVRIPFFAKLTPNVTDIVSI
AKAAKEGGADGVTATNTVSGLMGLKADGTPWPAVGIGKRTTYGGVSGTAIRPIALRAVTA
IARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAVQNQDFTVIEDYCTGLKALLYL
KSIEELQDWDGQSPATVRHQKGKPVPHIAELTGKKLPSFGPYLEQRKKIIAENKIKLKER
NAALPPLTRNCFIPKKPIPAIKDVIGKTLKYLGAYGELSNIEHVVALIDEEMCINCGKCY
MTCNDSGYQAIQFDPETHLPTVTDACTGCTLCFSVCPIIDCIKMVSRTTPYEPKRGLPLA
VNQEG
NT seq
3078 nt
NT seq
+upstream
nt +downstream
nt
atggccccggtgctcagcaaggacgcggcggacatcgagagtatcctggctttaaaccct
cgaacacaaactcatgctactttacgttctacttcggccaagaaattggacaagaaacat
tggaaaagaaatcctgataagaactgttttaactgcgagaagctggaaaataattttgat
gacatcaagcacacgactcttggtgagcgaggagctctccgagaagcaatgagatgcctg
aagtgtgcagatgccccctgccagaaaagctgtccaacgaatctagctatcaagtcattc
atcacaagtattgcaaacaagaattactatggagctgctaaaatgattttttctgacaac
ccactcggtctgacttgtggaatggtgtgcccaacctctgatctgtgcgtaggtggatgc
aatttatatgccactgaagagggaccaattaatattggaggcctacagcagtttgctact
gaggtattcaaagcaatgaatatcccgcagatcagaaatccatcactgcctcccccagaa
aaaatgcctgaagcttattccacaaagattgctctttttggtgcaggaccagcaagtatc
agttgtgcgtcttttttggctcgattaggctactctgacatcactatatttgaaaaacaa
gaatatgctggtggtttaagcatttctgaaatcccacagtttcggctgccatatgatgtg
gtaaattttgagattgagcttatgaaggaccttggtgtaaagataatttgtggtaaaagc
ctttctgtgaatgaaatgactctgagcactttgaaagaagaagggtacaaagctgctttc
attgggataggtttacctgaacccaataaagacagcatctttgaaggcttgacacaggac
cagggattttacacatccaaagactttttgccacttgtagccaagagcagtaaagcagga
atgtgcgcctgtcactctccattgccatcgatacagggagccgtgattgtactcggagct
ggagacactgctttcgactgtgctacatccgctttacgttgtggagcccgccgtgtgttc
gtcgtcttcagaaaaggctttgttaatataagagctgtccccgaggagatggagctcgcc
aaggaagaaaagtgcgaatttttgcctttcttatccccacgcaaggttatagttaaaggt
gggagaattgttgctatgcagtttgttcgtaccgagcaagatgaaactggaacctggaaa
gaagatgaagatcagatcgtgcatctgaaagcagatgtggtcatcagtgcttttggttcc
attctgagtgatcctaaagtaaaggaagccttgaaccctctaaaatttaacagatggggt
ctcccagaagtagatcctgaaactatgcagaccagtgaaccatgggtgtttgcaggtggt
gatattgttggtatggctaacactacagtggaatcagtgaatgatggaaagcaagcctct
tggtacattcacaaatatatacagtcacaacatggagcttcagtttcttcccagcctgag
ctacccctgttttatactcctattgatctggtggacattagcgtggaaatggctggattg
aagttcatcaatccttttggtcttgcgagtgcaaccccagctactagcacatcaatgatt
cgaagagcttttgaagcaggttggggcttcgccctgactaaaactttctctcttgataag
gacattgtgacaaatgtttcacccagaatcattcggggtaccacctctggccccatgtat
ggccctggacagagttccttcctgaatattgagctcatcagtgaaaaaacagcagcatat
tggtgtcaaagtgtcactgaactaaaggctgactttccagacaatattgtgattgccagc
atcatgtgcacttacaacaaaaatgactggatggaactctccaaaaaggctgaggcttct
ggagcagatgccctggagttaaatttatcgtgtccacatggcatgggagaaagaggaatg
ggcctggcctgcgggcaggatccagagctggtgcgcaacatctgccgctgggttaggcaa
gctgttcggattcctttttttgccaagttgaccccaaatgtcactgatatcgtcagcatc
gcaaaggctgcaaaggaaggaggtgctgatggtgttacagccactaacactgtctcaggc
ctgatgggattaaaagctgatggtacaccctggccagcagtaggcattggcaagagaact
acttatggaggagtgtctggcacagccattagacccattgctttgagagctgtgacagcg
attgctcgtgctttgcctggatttcccatcttggccactggtggaattgactcagctgaa
agtggtcttcaatttcttcacagtggagcttcggttcttcaggtctgcagtgctgtccag
aatcaggatttcactgtaattgaagactactgcaccggcctcaaagccctgctttatctg
aaaagcatcgaggaactacaagactgggatgggcagagtccagctactgtaagacatcag
aaaggaaaaccggttcctcacattgctgaactgactggaaagaaactgccaagttttgga
ccttatcttgagcaacgcaagaaaatcatagcagagaacaagattaaattgaaagaaaga
aatgcagctttgccacctctcacaagaaactgtttcattcccaaaaagccgattcctgcc
atcaaggatgtcattggaaaaactctgaaatatcttggagcatatggtgaactaagcaac
atcgaacacgttgtggctttgattgatgaagaaatgtgtatcaactgtggtaaatgttac
atgacctgcaatgattctggctatcaggccatccagtttgaccccgaaacccacctgcca
accgttactgacgcttgtacaggctgtactctgtgtttcagcgtctgccctattatcgac
tgcatcaagatggtttccaggacaacaccttatgaaccaaaaagaggcttgcccttagct
gtgaatcaggagggttaa
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