Serratia fonticola DSM 4576: WN53_12040
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Entry
WN53_12040 CDS
T04030
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sfw
Serratia fonticola DSM 4576
Pathway
sfw00300
Lysine biosynthesis
sfw00550
Peptidoglycan biosynthesis
sfw01100
Metabolic pathways
sfw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sfw00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
WN53_12040 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
WN53_12040 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
WN53_12040 (murF)
Enzymes [BR:
sfw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
WN53_12040 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Lipase_GDSL_2
Motif
Other DBs
NCBI-ProteinID:
AKG69784
UniProt:
A0A0F7HAL5
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Position
2708425..2709786
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AA seq
453 aa
AA seq
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MIPISLQTLAAVLDAELIGTDCIITEVTRDTRQVTAGCLFVALKGERFDAHNFAADAVAA
GAGALLVSKRLLVEAPQLVVKDTSLALGQFAAWVRQQVPAKVVALTGSSGKTSVKEMTAA
ILRECGEVLHTAGNYNNEIGVPLTLLRLEPQHDFAVVELGANHIGEIAYTTALAQPQSAL
VNNLAAAHLEGFGSLAGVAQAKGEIFAGLPADGVAILNADSNDWPHWQAQLQGKTVWRFS
PQAAESVDFFASDIQVKGSVTHFTLHSPFGTVAIELPLPGRHNVANALAAAALAMSVGAT
LAAVSAGLQQLQAVPGRLFPIALAQGKLLLDDSYNANVGSMTAAAQVLAEMPGYRVMVVG
DMAELGAEAEECHRQVGEAARLAGIDKVISVGGLSQVLSSAAGNGEHYQDKTAVTARVAE
LLSAHAVITVLIKGSRSAAMEQVVRALQEKAPC
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgatctccctccagacgctggcggcggtattggatgccgagctgattggcacc
gactgcatcattacagaagtgacgagggatactcgtcaggtcactgcgggttgcctgttt
gtggccctgaaaggcgagcgtttcgatgctcacaactttgccgccgatgctgtcgccgct
ggcgcaggcgctttgctggtaagtaagcgcttattggtggaggctccgcaactggtggtg
aaagataccagtctggcactggggcagtttgccgcttgggtacgtcagcaggtgccagcc
aaagtggtggcgctgaccggttcatcgggcaagacctcggtgaaagagatgaccgcggcc
attttacgtgaatgtggcgaagtgctgcataccgccgggaattacaataacgagattggc
gtgccgctaacgttgctgcgtttagagccgcagcatgattttgcggtggttgaactgggt
gccaaccatatcggtgagattgcctataccaccgccttggcgcaaccgcagagcgcgctg
gtgaataatctggccgctgcccatctggaaggttttggctcactggcaggcgttgcgcag
gccaagggcgaaatctttgccggtttgccggcggatggcgtggcgatcctcaacgccgat
agcaacgactggccgcactggcaggcacagttacagggcaagacagtctggcgtttctcc
ccccaggctgcggaatcagtggatttctttgccagcgatatccaggtgaaagggagcgtg
actcacttcaccctgcacagcccgttcggcacggtggcgattgagttgccattgccgggc
cgccataacgtggccaatgcgttggcggcagcagcattggcgatgtcggttggcgctacg
ctggccgccgtgagtgcaggcttgcaacagcttcaggcagtgccagggcgtttgttcccg
atcgccttggcgcaaggcaagctgttgctcgatgacagctataacgccaacgtcggctcc
atgacggcagcagcgcaggtgctggcagaaatgccgggttatcgcgtgatggtcgttggc
gatatggccgagttgggtgcagaggccgaagagtgtcatcgtcaggtgggtgaagctgcc
cgtctggccggtattgataaagtcatcagcgtgggtgggctgagccaggtattgagctcc
gccgccggtaacggtgaacattatcaggataaaacagcagtgaccgcgcgcgtagcggaa
ctactctcagcacatgcggtaattaccgtgttaatcaaaggttcacgtagtgccgcaatg
gagcaggtagtacgcgcgttacaggagaaagcaccatgttag
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