Shigella flexneri 2457T (serotype 2a): S0032
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Entry
S0032 CDS
T00128
Symbol
carB
Name
(GenBank) carbamoyl-phosphate synthase large subunit
KO
K01955
carbamoyl-phosphate synthase large subunit [EC:
6.3.5.5
]
Organism
sfx
Shigella flexneri 2457T (serotype 2a)
Pathway
sfx00220
Arginine biosynthesis
sfx00240
Pyrimidine metabolism
sfx00250
Alanine, aspartate and glutamate metabolism
sfx01100
Metabolic pathways
sfx01110
Biosynthesis of secondary metabolites
sfx01240
Biosynthesis of cofactors
Module
sfx_M00051
De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:
sfx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
S0032 (carB)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
S0032 (carB)
00220 Arginine biosynthesis
S0032 (carB)
Enzymes [BR:
sfx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
S0032 (carB)
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Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
CPSase_L_D3
MGS
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
ATP-grasp_4
ATPgrasp_Ter
CoA_binding_2
BamE
Motif
Other DBs
NCBI-ProteinID:
AAP15577
UniProt:
P63738
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All DBs
Position
29733..32954
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AA seq
1073 aa
AA seq
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MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEM
ADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATA
DAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGG
IAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAM
GIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEM
NPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIP
RFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEA
LTKIRRELKDAGAERIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVG
ITGLNAEFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDT
AYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVN
CNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVP
VIGTSPDAIDRAEDRERFQHAVDRLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVL
GGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIME
HIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLI
EVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKF
PGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDL
AAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGR
RAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK
NT seq
3222 nt
NT seq
+upstream
nt +downstream
nt
atgccaaaacgtacagatataaaaagtatcctgattctgggtgcgggcccgattgttatc
ggtcaggcgtgtgagtttgactactctggcgcgcaagcatgtaaagccctgcgcgaagag
ggttaccgcgtcattctggtgaactccaacccggcgaccatcatgaccgacccggaaatg
gccgatgcgacctacatcgagccgattcactgggaagtggtacgcaagattattgaaaaa
gagcgcccggacgcggtgctgccaaccatgggcggtcagacggcgctgaactgcgcgctg
gagctggaacgtcagggcgtgttggaagagttcggtgtcaccatgattggtgccactgcc
gatgcgattgataaagcagaagaccgccgtcgtttcgacgtagcgatgaagaaaattggt
ctggaaaccgcgcgttccggtatcgcacacacgatggaagaagcgctggctgttgccgct
gacgtgggcttcccgtgcattattcgcccatcctttaccatgggcggtagcggcggcggt
atcgcttataaccgtgaagagtttgaagaaatttgcgcccgcggtctggatctctctccg
accaaagagttgctgattgatgagtcgctgatcggctggaaagagtacgagatggaagtg
gtgcgtgataaaaacgacaactgcatcatcgtctgctctatcgaaaactttgatgcgatg
ggcatccacaccggtgactccatcactgtcgcgccagcccaaacgctgaccgacaaagaa
tatcaaatcatgcgtaacgcctcgatggcggtgctgcgtgaaatcggcgttgaaaccggt
ggttccaatgtccagtttgcggtgaacccgaaaaacggtcgcctgattgttatcgaaatg
aacccacgcgtgtcccgttcttcggcgctggcgtcgaaagcgaccggtttcccgattgct
aaagtggcggcgaaactggcggtgggttacaccctagacgaactgatgaacgacatcact
ggcggacgtactccggcctccttcgagccgtccatcgactatgtggttactaaaattcct
cgcttcaacttcgaaaaattcgccggtgctaacgaccgtctgaccactcagatgaaatcg
gttggcgaagtgatggcgattggtcgcacgcagcaggaatccctgcaaaaagcgctgcgc
ggcctggaagtgggcgcaactggcttcgacccgaaagtgagcctggatgacccggaagcg
ttaaccaaaatccgtcgcgaactgaaagacgcaggcgcagagcgtatctggtacatcgcc
gatgctttccgcgcgggcctgtctgtggacggcgtcttcaacctgactaacattgaccgc
tggttcctggtacagattgaagaactggtgcgtctggaagagaaagtggcggaagtgggc
atcactggcctgaacgctgaattcctgcgccagctgaaacgcaaaggctttgccgatgcg
cgcttggcaaaactggcgggcgtacgcgaagcggaaatccgtaagctgcgtgaccaatat
gacctgcacccggtctacaagcgcgtggatacctgtgcggcagagtttgccaccgacacc
gcttacatgtactccacttatgaagaagagtgcgaagcgaatccgtctaccgaccgtgaa
aaaatcatggtgcttggcggcggtccaaaccgtatcggtcagggtatcgaattcgactac
tgctgcgtacacgcctcgctggcgctgcgtgaagacggttacgaaaccattatggttaac
tgtaacccggaaaccgtctctaccgactacgacacttccgatcgcctctacttcgagccg
gtaactctggaagatgtgctggaaatcgtgcgtattgagaagccgaaaggcgttatcgtt
cagtacggcggtcagaccccgctgaaactggcgcgtgcactggaagccgctggcgtaccg
gttatcggcaccagcccggatgctatcgaccgtgcggaagaccgtgaacgcttccagcat
gcggttgaccgtctgaaactgaaacaaccggcgaacgccaccgttactgctattgaaatg
gcagttgagaaggcaaaagagattggctacccgctggtggtgcgtccgtcttacgttctc
ggcggtcgggcgatggaaatcgtctatgacgaagctgacctgcgtcgctacttccagacg
gcggttagcgtgtctaacgatgcgccagtgttgctggatcatttccttgatgacgcagta
gaagttgacgtggatgccatctgcgacggcgaaatggtgctgattggcggcatcatggag
cacatcgagcaggcgggtgtgcactccggtgactccgcatgttcgctgccagcgtacacc
ttaagtcaggaaattcaggatgtgatgcgccagcaggtgcagaaactggccttcgaattg
caggtgcgcggtctgatgaacgtgcagtttgcggtgaaaaacaacgaagtttacctgatt
gaagtaaacccgcgtgcggcgcgtactgttccgttcgtctccaaagccaccggcgtaccg
ctggcaaaagtggcggcgcgtgtgatggctggcaaatcgctggctgagcagggcgtaacc
aaagaagttattccgccgtactactcggtgaaagaagtggtgctgccgttcaataaattc
ccaggcgttgacccgctgttagggccagaaatgcgctctaccggggaagtcatgggcgtg
ggccgcaccttcgctgaagcgttcgccaaagcgcagctgggcagcaactccaccatgaag
aaacacggtcgtgcgctgctttccgtgcgcgaaggcgataaagaacgcgtggtggacctg
gcggcaaaactgctgaaacagggcttcgagctggatgcgacccacggcacggcgattgtg
ctgggcgaagcgggtatcaatccgcgtctggtaaacaaggtgcatgaaggccgtccgcac
attcaggaccgtatcaagaatggcgaatatacctacatcatcaacaccacctcaggccgt
cgtgcgattgaagactcccgcgtgatccgtcgcagtgcgctgcaatataaagtgcattat
gacaccaccctgaacggtggtttcgctaccgcgatggcgctgaatgccgatgcgactgaa
aaagtaatttcggtgcaggaaatgcacgcacagatcaaataa
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