Shigella flexneri 2457T (serotype 2a): S3657
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Entry
S3657 CDS
T00128
Symbol
purH
Name
(GenBank) phosphoribosylaminoimidazolecarboxamide formyltransferase, AICAR formyltransferase; IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
sfx
Shigella flexneri 2457T (serotype 2a)
Pathway
sfx00230
Purine metabolism
sfx00670
One carbon pool by folate
sfx01100
Metabolic pathways
sfx01110
Biosynthesis of secondary metabolites
Module
sfx_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sfx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
S3657 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
S3657 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
sfx04147
]
S3657 (purH)
Enzymes [BR:
sfx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
S3657 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
S3657 (purH)
Exosome [BR:
sfx04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
S3657 (purH)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
NSP2_assoc
Motif
Other DBs
NCBI-ProteinID:
AAP18694
UniProt:
Q83IR9
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Position
3546727..3548316
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AA seq
529 aa
AA seq
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MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGF
PEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLE
DAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEGSLTLATRFDLAIKAF
EHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYI
EENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSI
LDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQ
NVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTQRQPTEQELRDALFC
WKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFP
FRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
NT seq
1590 nt
NT seq
+upstream
nt +downstream
nt
atgcaacaacgtcgtccagtccgccgcgctctgctcagtgtttctgacaaagccggtatc
gtcgaattcgcccaggcactttccgcacgcggtgtggagctgctgtctacagggggcact
gcccgtctgttagcagaaaaaggtctgccggtaaccgaagtttccgattacaccggtttc
ccggagatgatggatggacgcgtgaagaccctgcatccgaaagtacatggtggcattctg
ggccgtcgcggccaggacgatgccattatggaagaacatcagatccagcctatcgatatg
gtggttgttaacctgtatccgttcgcccagactgttgctcgtgaaggctgctcgctggaa
gatgcggttgagaacatcgatatcggcggcccgaccatggtgcgctccgccgctaagaac
cataaagatgtcgcaatcgtggtgaagagcagcgactacgacgccattattaaagagatg
gatgacaacgaaggatcgctgacgcttgcaacccgtttcgacctcgccatcaaagccttc
gaacacactgccgcctacgacagcatgattgccaactacttcggcagcatggttccggcg
taccacggtgaaagcaaagaagccgccggtcgcttcccacgcacgctgaacctgaacttc
attaagaagcaggatatgcgttacggcgagaacagccaccagcaggctgccttctatata
gaagagaatgtgaaagaagcctccgttgctaccgcaacccaggttcagggtaaagccctc
tcttataacaacatcgccgataccgatgcggcgctggagtgcgtgaaagagttcgccgag
ccggcatgtgtgattgtgaagcacgccaacccttgcggtgtagctatcggcaattccatt
cttgatgcttacgatcgcgcgtacaaaaccgacccaacctccgcattcggcggcatcatt
gcctttaaccgcgagctggatgcggaaaccgcacaggccatcatttctcgtcagtttgtc
gaagtgattattgcgccttccgccagcgaagaagccctgaaaatcaccgccgccaagcag
aacgtacgcgttctgacctgcggtcagtggggcgagcgtgttccgggtcttgatttcaaa
cgcgtgaacggcggtctgctggttcaggatcgtgacctggggatggtcggtgcggaagaa
ctgcgcgtcgtcacccaacgtcagccgaccgaacaggaactgcgtgatgcgctgttctgc
tggaaagtggcgaaattcgtgaaatccaatgctatcgtctatgccaaaaacaatatgacc
atcggtattggcgcgggccagatgagccgcgtgtactccgcgaaaatcgccggtattaaa
gctgccgatgaaggcctggaagtgaaaggttcctcgatggcttctgacgcgttcttcccg
ttccgcgacggtattgatgccgccgccgctgcgggcgtgacctgcgtaatccagcctggc
ggttccatccgtgatgacgaagtgattgccgccgccgacgagcacggtattgcgatgctc
ttcaccgacatgcgccacttccgccattaa
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