Streptomyces fagopyri: GFH48_07290
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Entry
GFH48_07290 CDS
T06986
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sfy
Streptomyces fagopyri
Pathway
sfy00270
Cysteine and methionine metabolism
sfy00480
Glutathione metabolism
sfy01100
Metabolic pathways
sfy01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sfy00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
GFH48_07290 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
GFH48_07290 (egtA)
Enzymes [BR:
sfy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
GFH48_07290 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
QFZ73092
UniProt:
A0A5Q0L7S5
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Position
1685349..1686707
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AA seq
452 aa
AA seq
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MSDSVSDCTERRSAVTEAEVEALVRGICFKTGPPRTLGVEVEWLVHELRPPRLPATPEQL
EAAYAALRTLTLRSALTVEPGGQLELSSAPAGSLMECIGSVSADLDAVRAVLREAGLGLS
GLGHEPWNPPNRYLREPRYDAMERYLDRTGPEGRAMMCSSASVQVCLDAGYEEPGPLGHG
RRWWLANQLGAVLVAAFAHSPLAQGRHTGWRSTRQSLWTAMDPGRSAAPALDGDPRAAWA
RHVLDAPVMCVRAPEGPWEVPEGLTFREWTRSGTPPNRADLDYHLTTLFPPVRPRGHLEL
RMIDAQPGEDGWIVPLAVTAALFDDPEAAEIAYRTVKPLAERAEGLPAPCNPLWIDAARH
GLTDPELREAAVTCFAAAAEALPRLGATTEVREAVARFTDRYVARGRCPADDLLSQFHSQ
FHGSLHDRSHDLSADRSEDRSQDRSHGKDIRT
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgtccgattcggtgagtgactgtacggagcgacgctccgccgtcaccgaggccgaggtg
gaagcgctggtccgaggcatctgcttcaagaccggaccaccccgcaccctcggtgtcgaa
gtggaatggctcgtccacgagctgcggccgccgcggctccccgcaacacctgaacagctc
gaagcggcctacgccgctctgcggaccctgaccctgcgttcggcgctcaccgtcgaaccc
ggcggccagctggagctcagctccgcacccgccggctccctgatggagtgcatcgggtcc
gtgtccgccgatctcgacgcggtacgcgcggtactgcgcgaggcgggcctcggcctcagc
ggcctcggccacgaaccctggaaccccccgaaccgctacctccgtgagccgcgctacgac
gccatggagcgctacctggaccgcacgggccccgagggccgggcgatgatgtgttcctcc
gcctcggtccaggtgtgcctggacgccgggtacgaggagcccggcccgctcggccacggg
cgccgctggtggctggcgaaccagctgggcgcggtcctagtggccgcgttcgcgcactcc
ccgctcgcccagggccgccacaccggctggcgttccacgcggcagtccctgtggacggcc
atggacccgggccggtccgccgcgcccgcgctggacggcgatccgcgcgccgcctgggcc
cggcacgtcctggacgcaccggtgatgtgcgtccgggcgccggaaggcccctgggaggtg
cccgaggggctgaccttccgggagtggacccggtccggcaccccgccgaaccgggcggat
ctggactatcacctcacgaccctgttcccgccggtgcgcccccgcgggcatctggaactg
cgcatgatcgacgcgcagccgggcgaggacgggtggatcgtgccgctcgcggtgacggcg
gcactgttcgacgacccggaggcggcggagatcgcctaccggaccgtcaagcccctcgcg
gagcgggcggaaggtctgccggctccgtgcaatccgctgtggatcgacgccgcccggcac
ggcctgaccgaccccgagctgcgcgaggccgccgtgacctgtttcgcggccgccgccgag
gcgctgccccgtctcggtgccaccacggaggtgcgggaggccgtcgcgcggttcacggac
cgctacgtggcccgggggcgctgccccgccgacgacctgctcagccagttccacagccaa
ttccacggttcgctccacgaccggtcccacgacctgtccgcagaccggtccgaagaccgc
tcccaggaccggtcccacgggaaggacatccgcacatga
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