Streptococcus gallolyticus UCN34: GALLO_0652
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Entry
GALLO_0652 CDS
T01171
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sga
Streptococcus gallolyticus UCN34
Pathway
sga00300
Lysine biosynthesis
sga00550
Peptidoglycan biosynthesis
sga01100
Metabolic pathways
sga01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sga00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GALLO_0652 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GALLO_0652 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GALLO_0652 (murF)
Enzymes [BR:
sga01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GALLO_0652 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CBI13144
UniProt:
A0AA36NM55
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Position
675482..676846
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AA seq
454 aa
AA seq
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MKLTLHEVAKVVGAKNTISEFDDVPLRQIEFDSRKIEKGDLFLPLKGARDGHDFIETAFE
NGAVATFSEREVAGHPYIWVDDCLEAFQALASYYLEKQRVDVIAVTGSNGKTTTKDMIAA
VLSTEYKTYKTQGNYNNEIGLPYTALHMPDDTEKIVLEMGQDHMGDIHLLSELAKPHIGV
VTLIGEAHLEFFGSREKIAEGKLQIVDGMDSDGILIAPADTIVDPYLPESQMVIRFGDGA
EIFVKDLQESKESLTFMTNVIDRPITLPVPGKYNATNAMVAAYVGKLLAISDDDIVEALE
TIELTRNRTEWKKAANGADILSDVYNANPTAMRLILETFSKIPANEGGKKIAVLADMKEL
GEQSVELHKRMIMSLSPETLDTLIFYGEDIAELAQLASQMFPIGKVYYFKKTADEDQFDA
MLETVQKVLQPADQILLKGSNSMQLAKVVEALEE
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaacattgcatgaagtcgccaaggttgttggcgctaaaaatactatttcggag
tttgatgacgttcccctgcgacaaattgaatttgacagtcgtaagattgaaaaaggggat
ttatttttaccattaaaaggtgcgcgtgatgggcatgattttattgaaactgcctttgaa
aatggtgctgttgcgactttttcagaacgtgaagtagctggtcatccatacatttgggtt
gatgattgcttagaggcttttcaagcgctagctagctattatcttgagaaacagcgtgtt
gatgttattgctgtgacagggtcaaatggtaaaacgacaaccaaagatatgattgctgcg
gttttatcaacagaatacaagacttataaaacacaaggcaactacaataacgaaattggt
ttgccatatacagcacttcatatgccagatgatacggagaaaattgtccttgaaatgggg
caagatcatatgggtgacattcatctgttgtcagaacttgcaaaaccacatatcggtgtg
gtgactttgattggtgaagctcatttggaatttttcggtagtcgtgagaaaatcgcagaa
ggtaaattgcaaattgttgatggcatggattcagatggcattttgattgcgccagctgac
acaatcgttgatccttatttacctgaaagccaaatggttattcgttttggtgacggcgca
gaaatttttgtgaaagatttgcaagaaagtaaggaatcgttgacctttatgacaaatgtg
attgaccgtccaatcaccctacctgtgcctggaaaatacaatgcgactaatgccatggtg
gcagcttatgttggtaaattattagccatttctgatgacgatattgtcgaggctcttgag
acaatcgaattaacgcgcaatcgtacggaatggaaaaaagcagccaacggtgctgatatt
ttgtcagatgtttacaatgctaatccaacggcaatgcgcttgattttagagacattttct
aaaattcctgccaatgagggcggtaaaaaaatcgctgtgcttgctgacatgaaagaattg
ggtgagcaatctgttgagcttcataaacgcatgattatgagcttgtcacctgaaacatta
gatacactcattttctatggggaagatattgccgagttggcacaacttgctagtcaaatg
ttcccaattggaaaagtttattatttcaagaaaacagctgacgaggatcaatttgatgcc
atgcttgaaactgttcaaaaagtattgcaaccagctgaccaaatcttgttgaaaggtagc
aactcaatgcagttagctaaagttgttgaagcactggaggaatag
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