Streptomyces globisporus: WQO_00140
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Entry
WQO_00140 CDS
T04209
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
sgb
Streptomyces globisporus
Pathway
sgb00010
Glycolysis / Gluconeogenesis
sgb00020
Citrate cycle (TCA cycle)
sgb00620
Pyruvate metabolism
sgb00785
Lipoic acid metabolism
sgb01100
Metabolic pathways
sgb01110
Biosynthesis of secondary metabolites
sgb01120
Microbial metabolism in diverse environments
sgb01200
Carbon metabolism
sgb01210
2-Oxocarboxylic acid metabolism
Module
sgb_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sgb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
WQO_00140
00020 Citrate cycle (TCA cycle)
WQO_00140
00620 Pyruvate metabolism
WQO_00140
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
WQO_00140
Enzymes [BR:
sgb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
WQO_00140
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
ALU91919
UniProt:
A0A0U3M4V1
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Position
41669..42625
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AA seq
318 aa
AA seq
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MDLLRQMLLIRRFEERCVELYSAATIRGFVHLYIGEEAVAVGVHQALDEADAVVSTYREH
GHALARGVPPEAVMAEMYGKNTGCSHGRGGSMHLFDAGRRFYGGNAIVGGGLPLAAGLAL
ADRMRGESRVTCCFFGDGAFAEGEFHETANLAALWGLPVLFVCENNLYAMGTALAREHAQ
TDLAMRAASYGMAAWAVDGMDAHAVEKAARGAVESIRAGSGPHFLEMRTYRFRAHSMYDP
DRYRPKGEVEEWKRHDPVTRLADGMRKAGFLDRDAQESLDHEAVEAIDRAVRAAEQAPEE
SAEDLLLHVTGRREEVPS
NT seq
957 nt
NT seq
+upstream
nt +downstream
nt
atggacctcctgcggcagatgctgctcatccggcggttcgaggagcggtgcgtcgagttg
tacagcgcagcgacgatccgcggcttcgtgcacctctacatcggtgaggaggcggtggcg
gtcggcgtccaccaggcgctcgacgaagcggacgcggttgtctccacttaccgtgaacac
ggccacgccctggcccgcggggtaccccccgaggccgtgatggcggagatgtacgggaag
aacaccgggtgtagccacgggcgcggcgggtccatgcacctcttcgacgccggccgccgc
ttctacggtggcaacgcgatcgtgggcggcggactgccgctcgccgcgggcctggcgctc
gccgaccgaatgcgcggcgagtcacgcgtgacctgctgtttcttcggcgacggagccttc
gccgagggcgagttccacgagaccgccaacctggcggcactctgggggctgcccgtgctc
ttcgtctgtgagaacaacctgtacgcgatgggaacggcccttgcccgcgagcacgcccag
acggacctggcgatgcgggcggcgtcgtacgggatggctgcctgggccgtcgacggcatg
gacgcacatgccgtggagaaggcggcgcgcggcgcggtcgagtccatccgggccggcagc
ggaccgcacttcctggagatgcggacgtatcgattccgggcacactcgatgtacgacccg
gaccggtaccggccgaagggcgaggtcgaggagtggaagcggcacgaccccgttacgcgc
ctggccgacggcatgcgcaaggccggttttctcgatagagacgcccaggagtccctggac
cacgaggccgtggaggccatcgaccgggccgtccgggccgccgagcaggctcccgaggag
tctgccgaggacctgctgctccatgtcaccggccgacgcgaggaggttccgtcgtga
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