Streptomyces griseorubiginosus: DWG14_04190
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Entry
DWG14_04190 CDS
T06099
Symbol
bkdA_1
Name
(GenBank) 3-methyl-2-oxobutanoate dehydrogenase subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sge
Streptomyces griseorubiginosus
Pathway
sge00280
Valine, leucine and isoleucine degradation
sge00640
Propanoate metabolism
sge00785
Lipoic acid metabolism
sge01100
Metabolic pathways
sge01110
Biosynthesis of secondary metabolites
sge01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
DWG14_04190 (bkdA_1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
DWG14_04190 (bkdA_1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DWG14_04190 (bkdA_1)
Enzymes [BR:
sge01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
DWG14_04190 (bkdA_1)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AYC39947
UniProt:
A0A101RUP7
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Position
complement(4738623..4739771)
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AA seq
382 aa
AA seq
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MTVESTAARKPRRSAGTRKSPSTKPELVQLLTPEGKRVKNAAYDKYVADITPEELRGLYR
DMVLTRRFDAEATSLQRQGELGLWASLLGQEAAQIGSGRALRDDDYVFPTYREHGVAWCR
GVDPTNLLGMFRGVNNGGWDPNSNNFHLYTIVIGSQTLHATGYAMGVAKDGADSAVIAYF
GDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTEKQTRVPLYQRAQGFGFPGVR
VDGNDVLASLAVTKWALERARAGEGPTLVEAYTYRMGAHTTSDDPSKYRADEEREAWEAK
DPILRLRRYLESSNHADEGFFAELETESEALGRRVREVVRAMPDPDRFAIFEHAYADGHA
LVDEERAAFAAYQASFADGEGA
NT seq
1149 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgcgcgcaagccgcgacgcagcgccgggacgaggaagtcc
ccgagcaccaagcccgaactggttcagctgctgacgcccgagggcaagcgcgtcaagaac
gccgcgtacgacaagtacgtcgccgacatcacccccgaagagctccgcggcctctatcgc
gacatggtgctcacccgtcgcttcgacgccgaggccacctccctccagcgccagggcgag
ctgggcctgtgggcctcgctgctcggccaggaggccgcccagatcggctccggccgcgcg
ctgcgcgacgacgactacgtcttccccacctaccgcgagcacggcgtcgcctggtgccgc
ggggtcgacccgaccaacctgctcggcatgttccggggtgtgaacaacggcggttgggac
cccaacagcaacaacttccacctctacacgatcgtcatcggctcccagacgctgcacgcc
accggctacgcgatgggcgtcgccaaggacggcgcggacagcgccgtgatcgcgtacttc
ggcgacggcgcctccagccagggcgacgtggcggaatcgttcaccttctccgcggtctac
aacgccccggtcgtgttcttctgccagaacaaccagtgggccatctccgagccgaccgag
aagcagacccgcgtcccgctctaccagcgcgcgcagggcttcggcttccccggtgtgcgg
gtcgacggcaacgacgtcctcgcctccctggccgtcaccaagtgggccctggagcgggcc
cgcgcgggtgaggggccgacgctcgtcgaggcgtacacctaccgcatgggtgcccacacc
acctccgacgaccccagcaagtaccgggccgacgaggagcgcgaggcctgggaggcgaag
gacccgatcctgcgcctgcgccggtacctggagtcctcaaaccacgcggacgagggattc
ttcgcggaactggagaccgagtccgaggcgttgggcaggcgagtgcgtgaggtggtgcgg
gcgatgccggatccggaccgcttcgcgatcttcgagcacgcgtacgcggacgggcatgcg
ctcgtcgacgaggagcgggccgcgttcgccgcctaccaggcgtcgttcgcggatggggaa
ggggcctga
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