Streptomyces griseofuscus: HEP81_00864
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Entry
HEP81_00864 CDS
T07010
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sgf
Streptomyces griseofuscus
Pathway
sgf00270
Cysteine and methionine metabolism
sgf00480
Glutathione metabolism
sgf01100
Metabolic pathways
sgf01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sgf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HEP81_00864 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
HEP81_00864 (egtA)
Enzymes [BR:
sgf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
HEP81_00864 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
QNT91198
UniProt:
A0A7H1PT18
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Position
971105..972439
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AA seq
444 aa
AA seq
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MSDVMDEGGDCTGHRATVTEAEVDALVQGICFKTGPPRTLGVELEWLIHDRDLPQRPVTP
ERLRAAYAAVRAVPLGSALTVEPGGQLELSSPPAASLMECVGTVSADLAAVRAVLDEQGL
VLVGLGHDPFRVPERFLREPRYDAMETCLDRTGPAGRHMMRASASVQVCVDAGHEEPGPL
GHGRRWWLAHQLGAVLVAAFANSPLIDRLPTGWLSSRQLMWAKIGAARAGAPPPREEPRS
AWARHVLDSPVMCVRRDGGPWEVPEGLTFREWTRGQGSRPPTRADLDYHLTTLFPPVRPR
GHLELRMIDAQPGEDGWIVPLAVTAALFDDPQAAETAYRCVKPLAERALNLPAPHNPLWS
DAARLGLADPELREVAAACFAAALDALPRLGAGTEVTGAVAGYLERYVARGRCPADDLLD
ALPGTPTAPAGSGPAAQGRKDVPS
NT seq
1335 nt
NT seq
+upstream
nt +downstream
nt
atgtccgatgtgatggacgagggtggcgactgtacggggcaccgtgcgaccgtcaccgag
gccgaggtggacgccctggtccagggcatctgcttcaagaccgggccgccccggaccctc
ggtgtggagctggagtggctcatccatgaccgggacctgccgcagcgtcccgtgacaccc
gaacgactgcgcgcggcctacgcggccgtgcgtgccgtacccctcggttcggcgctcacc
gtcgaacccggcggccagctggagctcagctcgccgcccgccgcctccctgatggagtgc
gtcggcaccgtctccgccgacctcgcggccgtccgcgccgtcctcgacgagcaggggctc
gtcctcgtcggtctcgggcacgatcccttccgcgtcccggagcggttcctgcgcgagccg
cgctacgacgcgatggagacctgcctggaccgcaccggaccggccgggcggcacatgatg
cgtgcctccgcctccgtgcaggtctgcgtggacgcgggccacgaggagccgggcccgctg
gggcacgggcggcgctggtggctggcgcatcagctgggcgcggtcctggtggccgcgttc
gccaactccccgctgatcgaccggctgcccaccggctggctgtccagccggcagctgatg
tgggcaaagatcggcgcggcccgggcgggcgcgcccccgccgcgcgaggagccgcggtcc
gcgtgggcccggcatgtactggactccccggtgatgtgcgtacgccgagacggcgggccc
tgggaggtccccgaggggctgaccttccgggagtggacacgggggcaggggtcccggccg
cccacccgggcggacctcgactaccacctgaccaccctgttcccgccggtcagaccgcgt
ggccatctggagctgcggatgatcgacgcgcagccgggcgaggacggctggatcgtgccg
ctcgcggtgacggcggcgctcttcgacgatccgcaggccgccgagaccgcctaccgctgt
gtgaagcccctggccgagcgggccctgaacctgccggccccgcacaatccgctgtggagc
gacgcggcccggctcgggctcgccgacccggagctgcgggaggtggccgccgcctgtttc
gcggcggcgctcgacgcgctgccccggctcggtgccggcaccgaggtgacgggcgccgtc
gcggggtacctggaacgctatgtcgcccggggccgctgcccggccgacgatctgctggac
gcgctgcccggcacccctaccgccccggccgggagcggccccgccgcccagggcaggaag
gacgttccctcatga
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