Streptomyces griseofuscus: HEP81_00978
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Entry
HEP81_00978 CDS
T07010
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
sgf
Streptomyces griseofuscus
Pathway
sgf00270
Cysteine and methionine metabolism
sgf00450
Selenocompound metabolism
sgf01100
Metabolic pathways
sgf01110
Biosynthesis of secondary metabolites
sgf01230
Biosynthesis of amino acids
Module
sgf_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sgf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HEP81_00978
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
HEP81_00978
Enzymes [BR:
sgf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
HEP81_00978
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Gene cluster
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
B12-binding
Motif
Other DBs
NCBI-ProteinID:
QNT91312
UniProt:
A0A7H1PTD2
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All DBs
Position
1111036..1113354
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AA seq
772 aa
AA seq
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MTTKSAAAAARATVYGYPRQGANRELKKAVEGYWKGRVTATELRATAAELRRATWHRLAE
AGLHEVPTGDFSYYDHVLDTTVMVGAIPDRHRAAVAADQLAGYFAMARGTQEVAPLEMTK
WFDTNYHYLVPELGPDTVFTADSAKQVAELTEALARGLSARPVLVGPVTYLLLAKPAPGV
PADFEPLTLLDRLLPVYAEILADLRAAGADWAQLDEPALVQDRTPAELNAAARAYRDLGA
LTDRPKLLVASYFDRLGEALPVLAKAPVEGLALDFTEAAAQNLDALAAVGGLPGKRLVAG
VVNGRNIWVNDLEKSLATLGTLLGLADRVDVSASCSLLHVPLDAAAERDIDPQILRWLAF
AEQKTAEIATLAKGLTLGTDAIAGELSANRADLASRAGSPLTHDPAVRARAAAVTEADAR
RSQSYTERTAAQRARLGLPLLPTTTIGSFPQTGELRTARADLRAGRIDTAGYEERIKAEI
REVIGFQEKAGLDVLVHGEAERNDMVQYFAEQLTGYLATQHGWVQSYGTRYVRPPILAGD
ISRPGPMTVRWTSYAQSLTDRPVKGMLTGPVTMLAWSFVRDDQPLGDTARQVALALRDEV
NDLELAGTSVIQVDEPALRETLPLRAADRPGYLDWATEAFRLSTCGVRPDTQIHTHMCYA
EFGDIVRAIDDLDADVISLEAARSHMQVARELADHGYPREAGPGVYDIHSPRVPSAEEAA
GLLRTGLGAIPAERLWVNPDCGLKTRGWPETRASLENLVTAARTVREELAGA
NT seq
2319 nt
NT seq
+upstream
nt +downstream
nt
gtgaccacgaagtccgcagccgcggcggcacgggccaccgtgtacggctacccccgccag
ggggcgaaccgggaactgaagaaggccgtcgagggctactggaagggccgcgtcaccgcc
accgaactgcgcgccaccgcagccgagttgcgacgcgccacctggcaccggctcgccgag
gccggcctgcacgaggtgccgaccggcgacttctcgtactacgaccatgtcctggacacc
accgtcatggtcggcgcgatccccgaccggcaccgggcggccgtcgccgccgatcagctg
gccggctacttcgcgatggcccgcggcacccaggaggtggcgccgctggagatgaccaag
tggttcgacaccaactaccactacctggtgcccgagttgggcccggacacggtgttcacg
gccgactcggccaagcaggtcgcggagctgaccgaagcccttgcccgcgggctcagcgcc
cgcccggtgctggtgggcccggtgacctatctgctgctggccaagcccgcgcccggcgtg
cccgcggacttcgagccgctgaccctgctggaccggctgctgccggtgtacgccgagatc
ctcgccgatctgcgggcggccggcgccgactgggcgcagctcgacgagcccgccctcgtc
caggaccgcaccccggccgagctgaacgccgccgcgcgcgcctaccgggacctcggcgcc
ctcaccgaccgcccgaagctgctggtcgcgtcctacttcgaccggctcggcgaggccctt
ccggtgctcgcgaaggcgccggtggagggcctggccctggacttcaccgaggccgccgcc
cagaacctggacgcgctggccgcggtcggcgggctgcccggcaagcggctggtcgcgggc
gtcgtcaacggccgcaacatctgggtcaatgacctggagaagtccctggccaccctcggc
accctgctgggcctggccgaccgggtggacgtctcggcctcctgctccctgctgcacgtg
cccctcgacgcggccgccgagcgcgacatcgacccgcagatcctgcgctggctcgccttc
gccgagcagaagacggcagagatcgccacgctcgccaagggcctcaccctcggcacggac
gccatcgccggggagctgtccgcgaaccgggccgacctcgcctcccgggccggctccccc
ctcacccacgacccggccgtgcgcgctcgcgccgccgccgtcaccgaggccgacgcccgc
cgctcacagtcgtacaccgagcgcaccgccgcgcagcgggcccggctcgggctgcccctg
ctgcccacgacgacgatcggatcgttcccgcagaccggtgaactgcgcaccgcgcgcgcc
gacttgagggcgggccggatcgacaccgcaggatacgaggagcgcatcaaggccgagatc
cgggaggtgatcggcttccaggagaaggccggtctcgatgtcctggtgcacggcgaggcc
gagcgcaacgacatggtgcagtacttcgccgagcagctcaccggctacctcgccacccag
cacggctgggtccagtcatacggcacccggtatgtgcggccgccgatcctggccggtgac
atctcccgccccgggccgatgacggtgcgctggacgtcgtacgcccagtcgctcacggac
cgaccggtcaagggcatgctcaccggtccggtcaccatgctcgcctggtccttcgtccgc
gacgaccagccgctcggggacaccgcgcggcaggtggccctcgcgctgcgggacgaggtc
aacgaccttgagctggccgggacttcggtgatccaggtggacgagcccgcgctgcgcgag
acgctgccgctgcgcgccgccgaccggcccgggtatctggactgggcgaccgaggcgttc
cggctgagcacctgcggggtgcgcccggacacccagatccacacgcacatgtgttacgcc
gagttcggtgacatcgtgcgggccatcgacgatctcgacgccgatgtgatcagcctggag
gcggcccgctcccatatgcaggtcgcccgtgaactggcggaccacggctatccgcgcgag
gccggtcccggtgtctacgacatccactccccgcgcgtgccgagcgccgaggaggcggcg
gggctgctgcgcaccgggctcggggcgatcccggcggagcggctgtgggtcaaccccgat
tgcggactgaagacccgcggctggccggagacccgcgcatccctggagaacctggtcacg
gccgcccgcacggtccgcgaggagctggccggggcctga
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