KEGG   Streptomyces griseofuscus: HEP81_03465
Entry
HEP81_03465       CDS       T07010                                 
Name
(GenBank) hydroxymethylbilane synthase
  KO
K01749  hydroxymethylbilane synthase [EC:2.5.1.61]
Organism
sgf  Streptomyces griseofuscus
Pathway
sgf00860  Porphyrin metabolism
sgf01100  Metabolic pathways
sgf01110  Biosynthesis of secondary metabolites
sgf01120  Microbial metabolism in diverse environments
sgf01240  Biosynthesis of cofactors
Module
sgf_M00121  Heme biosynthesis, plants and bacteria, glutamate => heme
sgf_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
sgf_M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:sgf00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    HEP81_03465
Enzymes [BR:sgf01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.61  hydroxymethylbilane synthase
     HEP81_03465
SSDB
Motif
Pfam: Porphobil_deam Porphobil_deamC NMT1
Other DBs
NCBI-ProteinID: QNT93770
UniProt: A0A426RVW1
LinkDB
Position
complement(3868086..3869045)
AA seq 319 aa
MSDKALRLGTRRSKLAMAQSGQVAETVRRVTGRPVELVEITTYGDTSREHLAQIGGTGVF
VTALRDALVRGEVDFAVHSLKDLPTAEPEDLVLAALPVREDPRDVLVARDDLKFTDLPRG
ARIGTGSPRRMAQLNAYARAHGLDIETVPIRGNVDTRIRYVRDGELDAVVLAAAGLHRIG
RIEEVTDFLSVDTVLPAPGQGALAIECAAQRADLIAALGELDDPFTRAAVTAERSLLAAL
EAGCSAPVGALADLLEGGQFVKEMRLRAVVGTTDGTRMVQLSTTGPVPQTHEGALALGSE
LAAEMLAQGAAGLMGERAH
NT seq 960 nt   +upstreamnt  +downstreamnt
atgagtgacaaggcactgcgactgggaaccaggcggagcaagctcgccatggcccagtcc
ggtcaggtggcggagaccgtccgccgggtgaccgggcgaccggtcgagctggtcgagatc
acgacgtacggcgacacctcccgcgagcacctcgcgcagatcggcggcaccggcgtcttc
gtcacggcgctgcgcgacgcgctggtgcgcggcgaggtcgacttcgcagttcactcgctc
aaggacctccccacggccgagcccgaggacctggtcctggccgccctgccggtgcgcgag
gacccgcgggacgtgctcgtcgcgcgcgacgacctgaagttcaccgacctgccgcgcggc
gcccgcataggcaccggctccccgcgccgcatggcccagctgaacgcgtacgcccgcgcc
cacggactggacatagagacggtcccgatccgcggcaacgtggacacccgcatccggtac
gtccgcgacggcgagctggacgcggtcgtcctggccgccgccggactccaccggatcggc
cgcatcgaagaggtgaccgacttcctgtcggtcgacacggttctgcccgcccccggccag
ggggccctggcgatcgagtgcgccgcccagcgcgcggacctgatcgcggcgctcggcgag
ctcgacgacccgttcacacgggccgccgtgaccgccgagcggtcactgctcgccgccctg
gaggccggttgcagcgcacctgtgggtgcgttggccgacttgttggagggcgggcagttt
gtcaaggaaatgcgcctgcgcgccgtcgtcgggaccaccgacggcacccgcatggtgcag
ttgtccaccaccggtcccgtgccccagacgcacgaaggtgcgctggcactcggtagcgaa
ctcgccgccgagatgctggcccagggcgcggccggtctgatgggggagcgagcacattga

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