Streptomyces griseofuscus: HEP81_04043
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Entry
HEP81_04043 CDS
T07010
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase subunit PurL
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
sgf
Streptomyces griseofuscus
Pathway
sgf00230
Purine metabolism
sgf01100
Metabolic pathways
sgf01110
Biosynthesis of secondary metabolites
Module
sgf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sgf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
HEP81_04043 (purL)
Enzymes [BR:
sgf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
HEP81_04043 (purL)
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
QNT94331
UniProt:
A0A7H1Q201
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Position
4507123..4509381
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AA seq
752 aa
AA seq
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MSRTPLDTVEHAAATPDVELPWAELGLKKDEYERVVEILGRRPTGAELAMYSVMWSEHCS
YKSSKVHLRQFGEKAPESDALLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAA
TGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGE
VVFDACYQGNPLVNAGAIGVMRHEDIHLAKASGAGNQVILYGARTGGDGIGGASILASET
FDDAKPSKRPAVQVGDPFQEKLLIECTLEAFREKLVVGIQDLGAAGLSCATSELASNGSG
GMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPAKVERFLEICAKWDVIATVIGEVT
DGDRLEIFWHGGKIVDVDPRTVAHDGPVYERPYARPSWQDELQADDANKLPRPATSEELR
EQVLKLVASPNQASKKWITQQYDHFVQGNTVLAQPEDSGMIRVDEESGLGVAIATDGNGR
YTKLDPYTGAQLALAEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAVRGLADGC
LQLGTPVTGGNVSLYNQTGEAAIHPTPVVAVLGVIDDVARRTPVAFQEEGQLLYLLGDTR
EEFGGSAWSQVIHDHLGGMPPVVDLERERLLAEILISASRDGMIDSAHDLSDGGLIQAVV
ESALLGGKGARLVVPDGLDAFTFLLSESAGRALVAVPRSEELRFNDMCGARGLPVTRIGV
VDGDSVEIQGEFTLSLADLREAHENTIPSLLA
NT seq
2259 nt
NT seq
+upstream
nt +downstream
nt
atgagccggacgcctctggacacggtcgagcacgcggccgcgacccccgacgtcgagctg
ccctgggccgaactcggcctgaagaaggacgagtacgagcgggtggtggagatcctcggc
cgccgtccgaccggcgcggaactcgccatgtactcggtcatgtggtccgagcactgctcg
tacaagtcctccaaggtccatctgcgccagttcggcgagaaggcgcccgagtcggacgcg
ctgctcgtcggcatcggcgagaacgccggtgtggtggacgtcggccagggctacgcggtc
accttcaaggtcgagtcgcacaaccacccctcgtacgtggagccctaccagggcgcggcc
acgggcgtcggcggcatcgtccgcgacatcatcgcgatgggcgcccgcccggtcgcggtg
gtcgacccgctgcgcttcggcgcggccgaccaccccgacaccaagcgcgtcctgccgggc
gtggtcgcgggcatcggcggctacggcaactgcctgggcctgcccaacatcggcggcgag
gtcgtcttcgacgcctgctaccagggcaacccgctggtcaacgccggtgccatcggtgtg
atgcggcatgaggacatccacctcgccaaggcttccggcgcgggcaaccaggtcatcctg
tacggcgccaggaccggcggcgacggcatcggcggcgcctcgatcctcgcgtccgagacg
ttcgacgacgcgaagccctcgaagcggcccgcggtgcaggtcggcgaccccttccaggag
aagctgctcatcgagtgcaccctggaggcgttccgggagaagctggtcgtcggcatccag
gacctgggcgcggccggactctcctgcgcgaccagtgagctggcgtccaacggctccggc
ggtatgcgcgtgaccctggacgacgtcccgctgcgcgactcgacgctctcgcccgaggag
atcctcatgagcgagtcgcaggaacgcatgtgcgcggtcgtggagccggccaaggtcgag
cgcttcctggagatctgcgcgaagtgggacgtcatcgccaccgtcatcggtgaggtgacc
gacggcgaccggctggagatcttctggcacgggggcaagatcgtcgacgtcgacccgcgc
acggtcgcgcacgacggtccggtctacgagcggccgtacgcgcgcccgtcctggcaggac
gagctccaggccgacgacgcgaacaagctgccgcgcccggcgacttcggaggagctgcgc
gagcaggtcctgaagctggtggcgtcgccgaaccaggcgtccaagaagtggatcacgcag
cagtacgaccacttcgtgcagggcaacacggtgctggcgcagcccgaggactcgggcatg
atccgggtggacgaggagtccggcctcggcgtcgccatcgcgacggacggcaacggccgt
tacaccaagctggacccgtacacgggcgcgcagctggcgctggcggaggcgtaccggaac
gtggcgacgacgggcgcgaagccgctcgcggtctcggactgcctgaacttcggctcgccc
gaggacccggcggtgatgtggcagttcgcggaggcggtacgcggcctcgcggacggctgt
ctgcaactcggcaccccggtgaccggcggcaatgtctcgctctacaaccagacgggcgag
gcggcgatccacccgacgccggtcgtcgcggtcctcggtgtgatcgacgacgtcgcccgc
cgtaccccggtcgccttccaggaggaggggcagctgctctacctcctcggcgacacccgc
gaggagttcggcggctccgcctggtcccaggtgatccacgaccacctgggcggtatgcct
ccggtggtcgacctggagcgtgagcggctgctggccgagatcctgatctccgcctcccgt
gacggcatgatcgactccgcgcacgacctgtccgacggcggtctgatccaggccgtggtg
gagtcggccctgctcggcgggaagggcgcgcgcctggtcgtcccggacggcctggacgcc
ttcaccttcctcctctccgagtcggccggccgcgccctcgtggccgtcccccgctcggag
gaactgcgcttcaacgacatgtgcggtgcccgcggcctcccggtcacccgcatcggcgtc
gtggacggcgactcggtggagatccagggcgagttcaccctctccctggccgacctgcgc
gaggcccacgagaacacgatcccgtccctgctggcgtag
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