Streptomyces goshikiensis: PET44_28365
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Entry
PET44_28365 CDS
T09307
Name
(GenBank) SDR family NAD(P)-dependent oxidoreductase
KO
K24559
protomycinolide IV synthase 2
Organism
sgk
Streptomyces goshikiensis
Pathway
sgk00522
Biosynthesis of 12-, 14- and 16-membered macrolides
sgk01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
sgk00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00522 Biosynthesis of 12-, 14- and 16-membered macrolides
PET44_28365
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
sgk01008
]
PET44_28365
Polyketide biosynthesis proteins [BR:
sgk01008
]
Polyketide synthase (PKS)
Modular type I PKS
cis-AT PKS
Protomycinolide IV synthase
PET44_28365
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
KR
Ketoacyl-synt_C
PKS_DH_N
PS-DH
SpnB_Rossmann
KAsynt_C_assoc
PP-binding
adh_short
Docking
CurL-like_PKS_C
Thiolase_N
Epimerase
RhiE-like_linker
NmrA
GDP_Man_Dehyd
ACP_syn_III
Polysacc_synt_2
Motif
Other DBs
NCBI-ProteinID:
WBY23216
LinkDB
All DBs
Position
6440601..6446531
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AA seq
1976 aa
AA seq
DB search
MTANDDKIRDYLKRVVAELHSTRQRLNALEDNAREPIAIVGMSCRLPGGVTTPESLWELV
DSGTDAVSPFPDDRGWDLDALHHPESGAVHSREGGFLHDSADFDAEFFGISPREALAMDP
QQRLLLETAWEVFERAGIDPASVRGSRTGVYAGVMYHDYGARLNEIPPGLEGYLVNGSAG
SIASGRVAYTLGLEGPAVTVDTACSSSLVAVHLAAQALRQRECDMALAGGATVLSTPDLF
IDFARLGGLASDGRCKAFSDAADGTSFAEGAGMLLLMRLSDAVDKGHTVLAVIRGSAVNQ
DGASNGLTAPNGLAQQRVIREALANADLGPDQIDAVEAHGTGTRLGDPIEAQALLHTYGK
SRSPERPLLLGSLKSNIGHTQAAAGVAGIIKTVLAMRHGRLPRTLHVTRPSSRVDWSAGA
VELLTQTQDWPGQGDAPRRAGVSSFGASGTNAHLILEGVPDSDDTAAEREPSAGGGAWLL
SGRTEAALRAQARRLHGHLAARPHVSPAAIGRTLARSRTPFEHRAVVIGQDTAALLSGLT
ELASGAAHGPGVITGRAARGRRTALLFTGQGSQRPGAGRRLYERYEVFARALDETAAELD
RHLDRPLREVMFAEPGSATAGLLDRTEYTQPALFALEVALFELVSAWGLRPDALLGHSVG
ELAAAHVAGVFTLPDAARLVTARGRLMGELPAGGAMAAIQAGGPEIEETITALTARRPAR
IAVAALNGPDATVISGDEDAVAELAALWRERGRRAKVLPVSHAFHSPRMDAALEPFARIA
RDVSYAEPRIPVVSNLTGEVASAATLCTPEYWVRHAREAVRFSDGFRTLRDQGIDTFVEL
GPDGVLSALGRDCLRQEEQDAPHQDGSTDRDTAGSPADGQERPVLTVPLLRRDRDETTTC
LGALAAVHTHGVPVDLAAVHGDGPAVDLPTYAFQRTRYWLDVPAPAAGLTTTGLDTADQP
LLPAAIDLPDGEGTVRTGLLSVRTHPWIADHRVQNRTVVPGAALLDIAAWAGTEAGCPRV
AELTFATPLVLPESGEGVRLRVTLSGPDAEGIRTIRIDSRPADAARAADAPSDWTRHASG
TLTPGTEEAGDGADVPADLLGVWPPADATPVALDADAVAAEYRRLADAGVTYGPVFRGLR
AVWRRGEEIFAEVRLPGQAAADASRYGMHPALLDALAHATGFGEQFTEAHGLLPFSWSDV
RIHVRGTDSLRVRIAPAGPDAVTVAAADPAGRPALTARSLTLRPVPAHRFPSPQERSTPL
YRLEWTSASASVTGHARPTPAAAEWGVLGDAGQALLKGVRDGAQAPVRTYDDLAALAASD
TPLPDHVLVELGHDGDDLAAGAHDLAERALAVVQGWLAHARFTDARLVVLTHGAVAAGTS
AVRPASAVAWGLLRSAQSEHPGRFVLVDADPSDPAASYRSLSRAVTSGASQLALRGDEIL
VPRLTHGANGQGAAAGPRGDATEPEAAAAMGPAPSGSLSGPWRADGTVLVTGGTGTLGKA
VARHLVTKHGVRHLILAGRRGADAPGAAGLAAELTDLGAVVNIVRCDAADRSALEGVLAA
VPAAHPLTAVVHTAGVLDDGIVTAQTLQRVSAVLRAKADAVTHLHELTRDLDLSAFVLFS
SAAGTLGSPGQSGYAAANSFLDAFAAWRRAQGLPAVSLAWGLWGDGGDGGDGDGGSAGAD
GMGASLAAADLARLRRSGILPLDPAEALELFDEACDPSRTEAVLLPIRLDLAGLRARAAR
GTVHAGVVPEVLHALVPPPAGAGPSSGAGTPDPAAGQEPPTTAAASGTLAEQLAGKPRGE
RLAVLRELVRTEIASVLGHADAQRVQLQFSFKEAGFDSLTAVELRNRLTAVTGTRLPATL
VFDHPTPAALVDHLEQELPKGGQKLPADVPAVLEALDRIRDGLATAVTDDNGRAHVAERL
QELLGTLAPPVAGVRPVNGSNGHDGQGPDELSVGERLAASSDDELFDLFDSDFRSM
NT seq
5931 nt
NT seq
+upstream
nt +downstream
nt
atgacggccaacgacgacaagatccgtgactacctgaagcgggttgtcgccgaactgcac
agcacgcgccagcggctgaacgcgctggaggacaacgcccgcgagcccatcgccatcgtg
gggatgagctgccggctgcccggcggggtgaccacccccgagagtctgtgggaactggtc
gactccggcaccgatgccgtctcgccgttccccgacgaccggggctgggacctggacgcg
ctgcaccacccggagtcgggagccgtccactcccgcgagggcggtttcctccatgacagc
gccgacttcgacgcggagttcttcggcatcagcccgcgagaggccctggccatggacccg
cagcagcggctcctgctggagaccgcctgggaggtgttcgagcgggccggtatcgacccg
gcctccgtccgcggctcgcgcacgggggtgtacgcgggtgtcatgtaccacgactacggc
gcccggctgaacgagatcccgccgggtctcgagggctacctggtcaacggcagtgcgggc
agcatcgcctccggccgggtggcctacaccctcgggctggagggtcccgccgtcaccgtc
gacacggcctgctcctcgtcactggtcgccgtgcacctggcggcgcaggcgctgcggcag
cgggagtgcgacatggcgctcgcgggcggcgcgaccgtcctgtccacccccgatctgttc
atcgatttcgcgcgactgggcggcctggcctccgacgggcgctgcaaggcgttctccgac
gcggccgacggcaccagtttcgccgagggtgccggaatgctactcctgatgcgcctgtcg
gacgcggtggacaagggccacaccgtactggcggtcatccgcggctccgccgtcaaccag
gacggtgccagcaacggcctgacggcccccaacggcctcgcccagcagcgggtgatccgc
gaggcgctcgccaacgcggacctgggccccgaccagatcgacgcggtggaggcacacggc
accggaacccggctcggcgaccccatcgaggcacaggccctgctgcacacgtacggcaag
agccgcagccccgaacggcctttgctgctcggctcgctgaagtccaacatcggccacacc
caggccgccgccggcgtggccggaatcatcaagacggtgctggcgatgcgccacggccgg
ctgccccgcaccctgcacgtcacccgtccctccagccgggtggactggtcggcgggcgcg
gtggaactgctcacgcagacacaggactggcccggccagggggacgccccgcgccgcgcc
ggcgtgtcctccttcggcgccagcggcaccaacgcacacctcatcctggagggcgtcccg
gacagcgacgacacggcggcggagcgcgaaccgtccgccggcggtggcgcctggctgctc
tcgggccggaccgaagcggcgctgcgagcccaggcccgcagactccacggccatctcgcc
gcccgcccccacgtgtcacccgccgcgatcggacggacgctggcccgctcccgtacaccg
ttcgagcaccgggccgtcgtcatcggacaggacaccgccgcactcctgagcggcctcacg
gagctggcgtccggcgccgcgcacggacccggggtgatcaccggccgggccgcacgcgga
cgccgtaccgcactgctcttcaccgggcagggcagccagcggccgggcgccgggcgccgg
ctctacgagcggtacgaggtcttcgcccgggccctggacgagacggccgcggaactcgac
cggcacctggaccgcccgctgcgcgaggtgatgttcgcggaaccgggcagcgcgacggcc
ggtctcctcgaccgaaccgagtacacccagcccgcgctgttcgccctggaagtcgccctc
ttcgagctggtgagcgcctggggcctgcgccccgacgcactcctggggcactcggtcggc
gaactggccgccgcccacgttgccggagtgttcaccctgcccgacgccgcccgcctggtg
acggcgcgggggcggctgatgggcgagctgccggccggtggcgccatggcggcgatccag
gcaggcggcccggagatcgaggagacgatcacggcgctcacggctcgtaggccggcgcgc
atcgccgtcgccgcactcaacgggcccgacgccaccgtgatctcgggcgacgaggacgcg
gtcgccgagctcgccgcactgtggcgggagcggggccgccgtgccaaggtgctgcccgtc
agccacgctttccactcgccgcgcatggacgccgcactggaaccgttcgcccggatcgcg
cgcgacgtctcctacgccgagccgcgcatcccggtggtctccaacctgaccggcgaggtc
gcgtcggccgcgacgctgtgcaccccggagtactgggtgcggcacgcgcgcgaggccgtg
cgcttcagcgacggcttccgcaccctgcgcgaccaggggatcgacaccttcgtcgaactg
ggaccggacggcgtgctgtccgccctgggacgtgactgcctgcgccaagaggaacaggac
gccccgcaccaggacggctcgacggaccgtgacacggccggttcccccgccgacgggcag
gagcgtcccgtgctgacggtgccgctgctgcgccgggaccgcgacgagacgaccacctgc
ctcggcgccctggccgccgtccacacccacggtgtccccgtcgacctcgcggccgtgcac
ggtgacgggcccgccgtcgacctccccacctacgccttccagcgcacgcgctactggctg
gacgtcccggcccccgccgccggcctcaccaccaccggtctggacacagcggaccagccc
ctgctcccggccgccatcgacctgcccgacggggaaggcaccgtacggaccgggctgctc
tccgtccgcacccacccgtggatcgccgaccaccgcgtccagaaccgcaccgtggtaccc
ggagcggccctcctggacatcgccgcctgggcgggcaccgaagcgggctgcccccgggtc
gccgagctgaccttcgccacgcccctcgtgctgcccgagagcggggagggggtccggctg
cgcgtgacgctgagcggtcccgacgcggaaggcatccgtacgatacgcatcgactcccgg
cccgccgacgccgctcgggcagccgacgccccctccgactggacccggcacgcgtccggc
accctcacccccggaaccgaggaggccggtgacggcgccgatgtgccggcggacctgctc
ggcgtctggccccctgccgacgcgaccccggtggccctcgacgcggacgccgtcgcggct
gagtaccggcgcctcgcggacgcgggcgtgacctacggccccgtgttccggggactgcgc
gccgtctggcggcgcggcgaagagatcttcgccgaggtccggctccccggccaggcggcc
gccgacgcctcgcggtacggcatgcacccggccctgctggacgctctggcgcacgccacc
ggattcggcgaacagttcaccgaggcccacggcctgctgccgttctcctggagcgacgtc
cggatccacgtccgcggcaccgactccctgcgcgtacggatcgccccggcgggacccgac
gccgtgaccgtcgcggcggccgacccggcgggccgcccggccctcaccgcccgctcactc
acgctgcgccccgtcccggcgcaccggttcccgagtccgcaggagcggagcacaccgttg
taccgactggagtggacgtcggcctccgcttcggtgaccggacacgcccgtcccacgccg
gcggcagcggagtggggcgtcctcggcgatgcgggccaggccctcctcaagggcgtacgc
gacggagcgcaggcaccggtacggacctacgacgatctggccgcgctcgcggcctccgac
acgcccctgcccgaccacgtcctggtggagctcggccacgacggggacgaccttgccgca
ggcgcccacgacctggccgaacgtgcgttggccgtggtgcagggctggctggcccacgcc
cgcttcaccgacgcacgactggtcgtgctgacacacggggcggtggcggccggcaccagc
gcggtccgcccggcctcggccgtcgcctggggactgctgcgcagcgcacagtccgagcac
ccgggccgcttcgtactggtcgacgcggacccgtccgacccggctgcctcgtaccgctcc
ctgtcgcgggccgtcacctcgggagcctcccaactcgccctgcgcggcgacgagatcctc
gtaccccgactcacccatggagcgaacgggcagggcgctgccgccggtccccgcggcgac
gccaccgagccggaagcggccgcggccatggggcccgccccgtcggggagcctttccggc
ccctggcgcgcggacggcaccgtgctcgtcacgggcggaaccggaacgctcggcaaggcc
gtggcccggcatctcgtgaccaagcacggcgtccggcacctgatactggccggccggcgc
ggtgcggacgccccgggcgcggccggactggccgccgaactgaccgacctgggcgccgtc
gtgaacatcgtccgctgtgacgccgccgaccgctcggcgctcgaaggggtgctggccgcc
gtccccgccgcgcacccgctcaccgctgtcgtgcacaccgccggtgtgctggacgacggc
atcgtcacggcacagaccctccaacgggtctcggcagttctgcgggccaaggcggacgcc
gtcacacacctgcacgaactgacccgtgacctggacctgtccgccttcgtcctcttctcg
tcggctgcgggcaccctcggcagtcccggccagtccggctacgcggccgccaacagcttc
ctcgacgcgttcgccgcctggcggcgcgcgcagggcctgcccgccgtgtccctggcctgg
ggcctgtggggtgacggcggtgacggcggtgacggcgacggcggtagcgcaggggccgac
ggcatgggagcgagcctggccgccgccgacctggcacggctgcgccgttccggaatcctg
cccctcgaccccgccgaggcattggaactgttcgacgaggcctgcgacccctccaggacc
gaggcagtgttgctgccgatccgcctcgacctggccggcctgcgtgctcgtgccgcccgc
ggcaccgtacacgcaggcgtggtacccgaagtgctgcacgccctggtgcccccgcccgcc
ggtgccggaccttcgtccggtgcgggcacgccggaccctgcggcgggccaggagcccccg
accacggccgcggcatccggcaccctggccgaacagctcgccgggaagccgcgcggcgag
cggctcgccgtcctcagggagctcgtgcgcaccgaaatcgcctcggtgctcgggcacgcg
gacgcccaacgcgtccaactccagttctccttcaaggaagccggattcgactcgctcacc
gccgtcgaactccgcaacaggctcaccgccgtcaccggaacgaggcttcccgccacactg
gtcttcgaccatccgacgccggcggcactcgtcgaccacctggaacaggaactgccgaag
ggcggtcagaaacttcccgcggacgtcccggccgttctggaggcactcgatcggatccgg
gacggactggccaccgctgtcaccgacgacaacggccgcgcccacgtcgcggaacgcctt
caggaactgctcggcacgctcgccccgccggtggcgggcgtccgcccggtcaacggctcg
aacggtcacgacgggcagggccccgatgaactgtcggtcggcgaacgcctcgccgccagc
tccgacgacgagctcttcgacctcttcgacagcgacttccgatcgatgtag
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