Sphingomonas glaciei: M1K48_12585
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Entry
M1K48_12585 CDS
T08593
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sglc
Sphingomonas glaciei
Pathway
sglc00300
Lysine biosynthesis
sglc00550
Peptidoglycan biosynthesis
sglc01100
Metabolic pathways
sglc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sglc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
M1K48_12585
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
M1K48_12585
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
M1K48_12585
Enzymes [BR:
sglc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
M1K48_12585
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UUR07752
UniProt:
A0ABY5MTJ8
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All DBs
Position
2559169..2560548
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AA seq
459 aa
AA seq
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MTAPLWTSAEIEDATGGTASAPFEVKGVTFDSREVEPGWLFVAMPGTVADGHDFVPGAFA
KGAAGAIVSRPVEGPHVLVADVPKALEQLARASRTRMTGKVFGVTGSVGKTGTKEALAAA
LGRRHPGRVHRSLKSYNNHVGVPLSLARMPRDSVYGVFEMGMNHAGEIRTLVAMVRPHVA
LITAIAPAHIENLGSVEAIADAKAEIFEGLEAGGTAIIPNNSPYRDRLLKAARRHAETMV
TFGSGDADVSALHAVRSDKGGSLVTARLGSADLTYTIAQPGEHWVGNSLAVLAAVEAVGA
DLAAAGLALGDMGGLKGRGQRHRVAVEGGHALLIDESYNANPVSMAATLGSLAGERVDGR
RLAVLGTMLELGEFSDEAHAGLAPAILEAKVDEVILVGEATRPLAAALDGKLPVTLVATA
AEATDALVARLGAGDAVLVKASNGIGLASLVERVAGGSA
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgcccccctgtggacctcggccgagattgaggacgcgaccggcggcaccgcctcc
gctccgttcgaggtcaagggtgtcaccttcgacagccgcgaggtggagccgggctggctg
ttcgtcgccatgccggggacggtcgccgacgggcatgatttcgtccccggggcctttgcc
aagggcgccgcgggcgcgatcgtcagccggccggtcgaggggccgcacgtgctggtcgcc
gacgttccgaaggcactcgagcaactggcgcgggcgagccggacgcggatgacgggcaag
gtgttcggggttaccggatcggtcggcaagaccggcaccaaggaagcgctcgccgcggcg
ctcggccggcgccatccgggccgggtccaccgctcgctcaagagctacaacaaccatgtc
ggcgtgccgctgagcctggcgcggatgccgcgcgacagcgtctacggcgtgttcgagatg
ggtatgaatcacgcgggcgagatccgcacgttggtcgccatggtccgcccgcacgtcgca
ttgatcaccgccatcgcccccgcccacatcgagaacctcggcagcgtcgaggcgatcgcc
gatgccaaggccgagatcttcgaagggctggaagccggcggcaccgcgatcatccccaac
aacagcccgtaccgcgaccgcctgctgaaagccgcgcggcgccatgccgagacgatggtc
accttcgggtcgggggatgccgacgtcagcgcgcttcacgcggtgcgcagcgacaagggc
ggaagcctggtcaccgcccgcctgggcagcgctgacctgacctataccatcgcgcagccg
ggcgagcattgggtcggcaacagcctggcggtgctggcagcggtcgaggcggtcggcgcc
gaccttgccgccgcggggctggcgctgggcgacatgggcgggctcaagggccggggccag
cgccaccgggttgcggtcgaaggcgggcatgccctgctgatcgacgaaagctacaacgcc
aatccggtcagcatggccgcgacactgggcagcctggcgggcgagcgggtcgacgggcga
cggctggcggtgctcggcaccatgctcgaactgggcgagttcagcgacgaggcgcatgcc
gggctggcccccgccatcctcgaggcaaaggtcgacgaagtgattctagtcggcgaggcg
acccgcccgctggccgccgcgctcgacggcaagctgccggtgacgctggtcgccaccgcc
gccgaggccaccgacgcgctggtggcacggctcggcgcaggggatgccgtgctggtcaag
gcgtccaacggcatcggccttgcctccttagtcgaacgggtggcagggggctcggcctga
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