Streptomyces glycanivorans: P8A20_10125
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Entry
P8A20_10125 CDS
T10510
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sgly Streptomyces glycanivorans
Pathway
sgly00290
Valine, leucine and isoleucine biosynthesis
sgly00660
C5-Branched dibasic acid metabolism
sgly01100
Metabolic pathways
sgly01110
Biosynthesis of secondary metabolites
sgly01210
2-Oxocarboxylic acid metabolism
sgly01230
Biosynthesis of amino acids
Module
sgly_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
Enzymes [BR:
sgly01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
P8A20_10125 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
P8A20_10125 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
WLQ63931
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Position
complement(2409423..2410850)
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AA seq
475 aa
AA seq
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MGRTLAEKVWDDHVVRRADGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPRTMAITVEGELPDSVTA
KDLILAIIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLRGRDHAPEGEDWDAAVEYWKTLRTDDDAVFDAEVVIDGAALAPFVTWGTNPGQGAPL
SANVPDPASYEDASERHAAEKALEYMGLTAGQPLREINVDTVFVGSCTNGRIEDLRNAAS
VLEGRKVADGVRMLVVPGSVRVALQAVEEGLDKVFTAAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDARTPAGVR
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgatggt
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcg
ttcgacggtctgcgtcaggccggccggccggtgcggcgactcgacctcaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtatcccgt
gcccagctggagaccctgcgcaagaactgcgcggagttcggcgtccggctgcacccgctg
ggtgacgtcgagcagggcgtcgtgcacgtcgtcggcccgcagctcggcctgacccagccc
ggcaccacggtcgtctgcggtgactcgcacacctccacccacggcgcgttcggagcgctg
gccttcggcatcggcaccagccaggtcgagcacgtcctggccacccagacgctcccgctg
gcccgcccccgcaccatggcgatcacggtcgagggcgaactccccgacagcgtcaccgcc
aaggacctcatcctggccatcatcgcccgcatcggcaccggcggcggccagggctacatc
ctcgaataccgcggctccgccatcgagaagctctcgatggaagcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcctatctgcggggccgtgaccacgcccccgagggcgaggactgggacgccgcggtggag
tactggaagacactgcgcaccgacgacgacgccgtcttcgacgccgaggtcgtcatcgac
ggtgccgcgctggcgcccttcgtcacctggggcaccaaccccggccagggcgcgcccctg
tcggccaacgtccccgaccccgcgtcgtacgaggacgcctcggagcgccacgccgccgaa
aaggccctggagtacatggggttgaccgccggccagccgctgcgtgagatcaacgtggac
accgtgttcgtaggttcctgcaccaacgggcgcatcgaggacctgcgcaacgcggcttcg
gtcctggagggccgcaaagtcgccgacggcgtacggatgctggtcgtccctggctccgtc
cgggtcgccctgcaggccgtcgaggagggtctggacaaggtcttcaccgccgccggcgcc
gaatggcggcacgcgggctgctcgatgtgcctcggcatgaaccccgaccagttggccccc
ggcgagcgctccgcctccacctcgaaccggaacttcgagggcaggcagggcaagggcggc
cgtacccacctggtctccccgcaggtcgccgccgccaccgccgtgctgggccatctggcc
tcgcccgccgatctgtccgacgcccgtacgcctgccggagtccgataa
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