Sphaerochaeta pleomorpha: SpiGrapes_0595
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Entry
SpiGrapes_0595 CDS
T01673
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sgp
Sphaerochaeta pleomorpha
Pathway
sgp00300
Lysine biosynthesis
sgp00550
Peptidoglycan biosynthesis
sgp01100
Metabolic pathways
sgp01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sgp00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SpiGrapes_0595
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SpiGrapes_0595
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SpiGrapes_0595
Enzymes [BR:
sgp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SpiGrapes_0595
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEV28444
UniProt:
G8QXE3
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All DBs
Position
complement(649886..651268)
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AA seq
460 aa
AA seq
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MEQRNGFSTQHYRVGQVASLCGGTLVKNGALDAEDVQFDSRLCSRGTVFFALPGEKEDGF
SFIGDAASKGCSAVIVSLANANEAKQRLSSSPCAVIAVANPLRSLQLLAKNYISQFPRVS
YVGITGSCGKTTTKEALAAITTIMGPTVKTPGNFNSEIGLPLSLLQVNKDTEYGIFEMGI
DHVGEMDRMVDMVKPDFALLTNIGISHLEKFGTQETIADEKGKIFHPDLKEGFLNKSCRY
CSFLEKKAPRKMRYFGYEDLSFTDLGLDGWAIHYEGQTFFVKCVGKHLLLDIIGAIKVAK
SLGANPSQIAQGLEGFVSMKGRSSIINGDVTIIEDYYNASLDSTNSILDYLQSLQWKGYK
KAVLGPMKELGTKSVQAHSLIARHLMKTHLDSTFLYGSEMKGAYDLLKKSGYGRGVFFTD
DFSELENRVAKDTRSGDLYLVKASRSVAMERIIPSIRDGR
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atggaacaacgtaatggtttctccacccagcattacagggttgggcaggtagcttccctc
tgtggggggaccttggtaaaaaacggtgccctcgatgccgaagatgtccaatttgactcc
cgcctctgttccaggggaacggttttttttgcactcccaggagaaaaggaagatggtttt
tccttcatcggcgacgctgcctcaaaagggtgcagtgccgttatcgtttcccttgcgaat
gcaaatgaggctaaacagagactctcttcttccccgtgtgccgttatcgccgttgcaaat
cccctgcgctctttgcagctccttgcaaaaaactatatttcccagtttccgagggtttcc
tatgtgggaatcaccggcagctgcgggaaaaccactacaaaggaagctctggctgccatc
actacgataatgggcccaacggtaaagacacctggaaactttaatagtgagatcggtctg
cccttaagccttttacaggtgaacaaggataccgagtatggaattttcgaaatggggatc
gaccatgtcggggagatggacaggatggtggatatggtcaaaccggactttgccctgttg
accaatatcggtatctcccatcttgagaaattcggtacccaggaaacaatcgcagacgaa
aaaggaaaaatcttccaccccgatctcaaagaaggctttcttaacaaatcctgcaggtat
tgttctttccttgaaaaaaaggccccgcgtaagatgcgctatttcggctatgaggacctg
tcgtttactgatctcgggctggatggctgggcaatccattatgaggggcagacttttttc
gtaaaatgtgttggcaaacatttgctgctggacataatcggggcgatcaaggtggcgaag
tccctcggggcaaacccttcccagatagcgcaagggcttgaagggttcgtctccatgaaa
ggaagaagttccattatcaacggtgatgtcaccatcatagaggattattacaatgccagc
cttgactcaaccaactccatcctcgattatctgcagtccttgcagtggaaggggtataag
aaagcagtgcttggcccaatgaaagaacttggtacgaaaagcgtccaggcccacagcctc
attgccaggcatcttatgaaaacgcacctggacagtacttttttatatgggtctgagatg
aaaggcgcctatgacctactgaaaaaatcaggctatggcaggggtgtgtttttcaccgat
gatttttcggaactggaaaacagggttgccaaagatacccgtagcggtgacctctatctt
gtcaaagcctcccggagcgttgcgatggaacggattattccatctatccgagatggtcgg
tag
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