Streptomyces griseus: SGR_4135
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Entry
SGR_4135 CDS
T00691
Name
(GenBank) putative dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
sgr
Streptomyces griseus
Pathway
sgr00290
Valine, leucine and isoleucine biosynthesis
sgr00770
Pantothenate and CoA biosynthesis
sgr01100
Metabolic pathways
sgr01110
Biosynthesis of secondary metabolites
sgr01210
2-Oxocarboxylic acid metabolism
sgr01230
Biosynthesis of amino acids
Module
sgr_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
sgr_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
sgr00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SGR_4135
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
SGR_4135
Enzymes [BR:
sgr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
SGR_4135
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
DUF4154
Motif
Other DBs
NCBI-ProteinID:
BAG20964
Kitasato:
SGR4135
UniProt:
B1VSL0
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Position
4833599..4835449
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AA seq
616 aa
AA seq
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MPQLRSRTVTHGRNMAGARALMRASGVASADIGKPIIAVANSFTEFVPGHTHLAPVGRIV
SEAIQAAGAVPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICIS
NCDKITPGMLMAAMRLNIPTVFVSGGPMEAGKATLVDGTVRKLDLVNAISDAVDESISDE
DILRIEENACPTCGSCSGMFTANSMNCLTEVLGLSLPGNGSVLATHTARKALYEDAGRTV
VEITKRYYEQDDETVLPRSIGTRAAFDNAMALDIAMGGSTNTILHLLAAAEEAELAYDLD
DINEVSRRVPCLSKVAPNVAPGGTYYMEDVHRAGGIPALLGELHRGGLLNEDVHSVHSDT
LAEWLKNWDVRGGSPSPEAIELWHAAPGCVRSATAFSQSERWDTLDLDAAGGCIRDVEHA
YSKDGGLAVLKGNLAVDGCVVKTAGVDESIWTFEGPAVVCESQDEAVDKILRKEIEPGDV
VVIRYEGPRGGPGMQEMLYPTSFLKGRGLGKVCALVTDGRFSGGTSGLSIGHASPEAASG
GTIALVEDGDRIRIDIPNRSIELLVDDAELATRREALNGVYAPKNRDRKVSAALRAYAAM
ATSADRGAVRDVSKLG
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgccgcagctgaggtcccgcacggtcacccacggacgcaacatggcgggcgcgcgcgcc
cttatgcgcgcgtcgggcgtagcgagcgcggacatcggcaagccgatcatcgccgtcgcc
aactcgttcaccgagttcgtccccggccacacccacctcgccccggtcggccggatcgtc
tccgaggcgatccaggcggcgggcgcggtcccgcgcgagttcaacaccatcgccgtggac
gacggcatcgcgatgggccacggcggcatgctctacagcctgccctcccgcgacctcatc
gccgactccgtcgagtacatggtcgaggcgcactgcgcggacgcgctgatctgcatctcc
aactgcgacaagatcaccccgggcatgctgatggccgccatgcgcctcaacatcccgacc
gtcttcgtctccggcggcccgatggaggccggcaaggccaccctcgtcgacggcacggtc
cgcaagctcgacctggtcaacgcgatcagcgacgcggtcgacgagtccatctccgacgag
gacatcctccgcatcgaggagaacgcctgccccacctgcggcagctgctccggcatgttc
accgccaactcgatgaactgcctgaccgaggtcctcggcctctctctccccggcaacggc
tccgtcctcgccacccacaccgcccgcaaggcgctgtacgaggacgccggccgcacggtc
gtcgagatcaccaagcgctactacgagcaggacgacgagacggtcctgccgcgctccatc
ggcacccgcgccgcgttcgacaacgcgatggcgctggacatcgccatgggcggctcgacc
aacacgatcctgcacctgctggccgccgccgaggaggccgagctggcgtacgacctcgac
gacatcaacgaggtctcgcgccgggtcccctgcctctccaaggtcgcccccaacgtcgcc
cccggcggcacgtactacatggaggacgtccaccgggccggcggcatccccgccctcctc
ggcgaactccaccgcggcggcctgctcaacgaggacgtgcactcggtgcactccgacacc
ctcgccgagtggctgaagaactgggacgtgcgcggcggctccccgtcccccgaggcgatc
gagctgtggcacgccgcccccggctgcgtccgctccgcgaccgccttctcgcagtccgag
cggtgggacaccctcgacctggacgcggcgggcggctgcatccgcgacgtcgagcacgcc
tactccaaggacggcggcctcgccgtcctcaagggcaacctcgccgtcgacggctgcgtc
gtgaagaccgccggcgtcgacgagtcgatctggaccttcgagggcccggccgtcgtctgc
gaatcgcaggacgaggccgtcgacaagatcctccgcaaggagatcgagccgggcgacgtc
gtcgtcatccgttacgagggcccgcgcggcggccccggcatgcaggagatgctctacccc
acgtccttcctcaagggccggggcctgggcaaggtctgcgcgctggtcaccgacggccgc
ttctccggcggcacgtcgggcctctccatcggccacgcctcgcccgaggcggcctccggc
ggcaccatcgcactcgtcgaggacggcgaccggatccgcatcgacatcccgaaccgctcc
atcgagctgctcgtcgacgacgccgaactggccacccgccgcgaggcgctcaacggcgtc
tacgcgccgaagaaccgcgaccgcaaggtctcggcggcgctgcgcgcctacgcggcgatg
gcgacgagcgcggaccgcggcgcggtcagggacgtctcgaagctcggctga
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