Streptomyces griseus: SGR_450 Help Entry SGR_450           CDS       T00691                                  Name (GenBank) putative NRPS Organism sgr  Streptomyces griseus SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AMP-binding Condensation PP-binding AMP-binding_C Motif Other DBs NCBI-ProteinID:  BAG17279 Kitasato:  SGR450 UniProt:  B1VQH8 LinkDB All DBs Position complement(514603..532029) Genome browser AA seq 5808 aa AA seqDB search MRMSTHRERLPLTEAQLGLWSAQRIDPASPVYLTAEYVELTGPLDERAFVAAVTRAVGEA DGLSVRFTADGDDVHQETGAIPPTGPGLHDLRTAEDPGTAALDWMEEERTAPVDMEHGAL YRHALLRTGDERWLWYHRCHHILLDAYGYARVAERVAELYGHACAGTEPPASPFAPLRDA VQEDRRYTDSEQHAADARFWQDLLADRPHPPTPARTAPTRVAPRSLRSRRTLGAADAERL AAFAQRSRATWPEAVTAAWALYLTRLTGTPEAVIGLPVSNRTGSVLARTPVTAVNVVPLR VAVDEREPVGDLLRRVTATLRRQRRHQRYRGERLRRDLQLFGHGRRLVGPQLNIKPFATD LAFGDCAGTVHSLAAGAVEDLNVTVGGRGGPDGLTGLDLVLDGNPDLYGPAELDAHLHRF ATLLDRLSRAEPDLPGARVGLLDEPERLRVLEEFNAPDDGDAEAAPAPDLVEGFTDQARR TPHAVALRCGDAHLTYAELADRAGRLASALTARGAGRGSLIAVALPRGEALLVALLAVAS AGAAYVPLDPRYPADRLRHMLADSRPLLLVTDRAHPWGADLPRLTVALDGTLPDATPGAG TESLSAPADGVPAGPPRSGDPADRRPGDPAYVIYTSGSTGRPKGVVVPRPALANLLAAMG RLLDLSGEDRLLAVTTVSFDIAALELFVPLLAGATVVLAADDDVSDPFALSALIRSSAPT VMQATPSLWRVLAEAAPDALGGLRALSGGEPLPADLADVLSRHANGLVNLYGPTETTIWS TAAVLHRGTPPHVGRPVRRTRAHVLDRTLAPAPVGVTGELHLAGDGVADGYLGRPALTAT RFVADPFGAPGARMYRTGDLARYRDDGTLEVLGRADSQVKIRGHRVEPGEVEAALLAHPS VAEAAVAAVPAPGGDLTLAAYCVLTRTGKEPGAGAAGEGDWADPLRHALAERLPEHLVPG HFVALERLPLTPNGKTDRAALPAVAPAAAPGAGRAPRAGAEALLCDLFAAVLGRSEASPD DDFFLLGGHSLSAARLVTALRSRTGVELPVRALFDHPTPARLADALERVGGLEGPGRTAG APPLVRRPRPARPPLSFGQRRLWFLARSQGEDGSYNIPLAIDVAARLDPAALRRALGDVA ARHEILRTVLPVEDGEAWQQVLDITAAEPGLAEAHVREARLGERVRAEAARPFDVERETP LRAVLFTVEPDPAEPGSAEPGPCGAETVAPVRQTLLLVLHHIAADEWSLPLLLDDLAAAY AARLDGSDPHPPRLPVDHIDFTLWQQDLVTARQEADAQFWRTRMRGAPEQLTLPWARPRP ARTGGPARTHDFGIDAELHQRVKALARRTRTTTFMVLHAAFAATLSQLGCGDDLVIGTPV AGRDDEALRGSVGFLINTLPLRTRLDATTGFLDLLERTRDDDLAALAHRSLPLERIVAEV NPPRLPGVSPLFQVLFAVREEFPDRAVLPGQTGRPRLVATGAAKFDLQCTVSEDPATGAT GQLEYRTELWDAAAADRFARALLHVLDQLTAHPERPVATTPTGAGGAVAAPEPHPVPATS LAELCAAQAARTPGRTALVSGADEITHADLDARSARLARLLADRGAGPGALVGVSLPRGA DLLVTLLAVARTGAAHLPVDPGFPAERIRMLLADAAPALLVTDRATARTLDADPRSVLLL DDPATVRAAAGAAPLAPRAAHGDAPAYVIHTSGSTGRPKGVVVTRAAVVNFLLCLADTLR FHGRERLLAVTTVGFDIAVLELFLPLVTGATVILADREQVRDPALLAELIDTARPTAMQA TPSLWRALLDTAPDAVRGLLALAGGEALAPDLARRLVAHGADLVNLYGPTETTIWSTAGR LDATDAEAPHVGTPLWNTRALVLGRGLVPLPVGVTGELYLAGDGLAQGYLGRPGQTAERF TADPCGPPGSRMYRTGDLARLRADGALEIVGRADHQVKIRGHRVEPAEVAAALRAHPAVE DAAVVAHRGPADPAPRLIAHLTGLTGSPEARTATAARIREELRAVLPGHLVPDLCLPLDA LPLTPNGKLDRAALPAPRPAAAPVGRAPAGQGEELLAALFADLLGLEQVGAEADFFALGG HSLLAARLAVRAAEALGRPLSVRQIFDTPTVAALAARPAAPETALPALEPVPHEGPLPLS PAQARLWFLSRLQPGTAYHLPFVLTLTGDVDHDALAAAVGDLAERHAVLRTVFPAADGAP VQHILDRPEPVRRRTARSAEEAEELLGALSAEPFDLAAEPPFRATVLAEPDRTRVLLLIH HIAADEWSVEPLLTDLSAAYRTRLAGGPPGLPPLGVAYTDYAHWQHALLDGGHLDGQAGF WRRTLRGAPAVLDLPTDRPRPETPTGRGGFVPFALPDEVASGLRALAADAAVTPFMVTQA ALCALLAGLGAGDDIPLGVPTAGRGERRTEELIGFFVNTLVLRTDLSGDPTFRELLARVR AVDLDAFDHAELPFERVVEELNPERGPANPLFQVMLTYQNRTSVPFTAPGVDAAFTLRET DTAKFDLIVGFTDHLADGSVDGAINYSADLFDATTVRALADRLVAFLARAVARPDTRIGS IGLLTAGEEDTLLRRWNPAGDHRGAPPVLDRFARAAADHPAAPALTDGGDTLTYAELDAR TNALARLLMSYGVGPEDRVALLLPRSATLVEAVLAVAKTGAAYVPVDPAHPRDRIAWTLR DAAPALVVTDSATAGRTPATCTAPVIVLDEEPHAGSRLRQPDGPVADAERTGPQRQDNAA YLIYTSGSTGRPKGVVVTGRNLARLFDATAEDAFGPDDVWTLFHSYAFDFSVWEMWGALL HGGRLVIVPGAVTRSPDEFLELLHHEGVTVLNQTPSACYQLTEALTAPGSPGLPPALRLV VLGGEALDPARLAPWLRDPEGPRLVNMYGITETTVHVTTHDLAPGTPAPGASPVGRAIDD LRVYVLDRRLRPVPPGVGGELYVAGAGLSRGYRGRHPLTAERFVADPFGAPGTRMYRSGD LARWSADGVLHYLGRADSQVSLRGFRVETAEIETVLRDPGGARSAAVLLREDLPTGPGLV AYTTGGTPADALRAACAARLPAYMVPTAFVALDRLPLTNNGKLDRAALPLPDTAPDGPPT GRAPRTPHEHLVARLYGEVLGRAPVAADEDFFALGGHSLLVTRLAGRVRAELGLDVPVRT LFEAPTVAALAARLTGLTRTQDARVPGPAPAAVRPERLPLSPAQARLWFLHRLGGSALTY AVPLLLRLRGPLDESALGRALAALARRHEILRTCYPEHEGRPVQQVLPEAAPVPLASALL DGESAQDAARRLAAEPFDLADRPPLRAHLLTGPGDERSLLLLVHHIAYDEASTGPLVRDL ARLYAAELDPDHGAPEPPALQYADYTLWHREATAAREDGLLAYWRTALAGAPEETSLPLD RPRPAEVDEHGDSVEFTVPADLHRAAARLARDNGATLFMVLQSALAVLLTGHGAGHDLPI GTLLSGRGERALEELPGLIANTVVLRTDTSGSPTFTELLARVRAVDLDAFDHGDLPFERL VDALAPQRSLSRHPIFQVALIHQNAPHRTLPFGPATVEAELVETRAAKFDLTLAVVEEPG TDGLRAALNYRTALFDRPTVEALAHRLTTLLHRLCTHPGLPVDQVPVLDEAEARRVLTAS AGPHVPLPGRTLVDLVREQAARSPAAEALRDGTRSWSYREFDTEADRLAGLLAEHGVRRG DTVVVAVPRSAELVLAVHAVQRAGAAYLPVDPAQPAARVSSQLQDAEAVLLITDPAAALP GEAVGGLPVLDVTADEVPRFTTVLDGPRPADPAYLLFTSGSTGRPKGVRVPHDAVANRLR WAQDAYRLTEEDRVLLKTPATFDVSVWELFWPLLAGATLVTAGPDDHRDPVAIARLLREH RVTTVHFVPSMLAAFTGTAAPADCATLRRVLASGETLTPAAAAGLLRLAPGAELHNLYGP TEAAVDVTAHPVTAADIASGRLPIGRPVWNTTTLVLDARLRPAPPGAAGELYLAGAQLAY GYHRRAALTATRFVADPYGPPGSRLYRTGDLARLRADGALEHLGRVDDQIKLRGQRVEPG EIRAVLDAHHGIAAAAVVAHEDTATGVTHLIGYVVPRTGEGAALPAGLAEHLAARLPAHL VPTALIPLPALPVTANGKLDRAALPAPRLTSPETRTAPRTDEELRLAALFAELLRTEHIG VDDSFFALGGDSILSIQLVAAARKAGLHFTPQDVFRHRTVAGLLAVAEPTTPAAPPRALP AAPDDGAPGRPTPLQEGLLFLSQYDGPGSTGAGDPLDVYHVQVAIRLTGDLDTDRLRTAL RTVVRRHAPLRTAFTGDGNGWTQRVHTDPEPEFAVLDLRRRKPREQERRAARRADDERRR RFDLSAPPLLRATLVRRPETCELVLTGHHLVLDGWSLPLLVRELLHTYAERELPEPPDYV LHRAWLDARDEQSAAEAWRDALDGVTEPTRLVPDDPGEQELPDQQTVWVDAELTERIAAF GRERELTLSTLTQAAWGLVLSAHTGRRDVVFGTVVSGRPAEVPGATEMIGLFVNTVPVRV TVRPQETLAALAARLQDEFTALLPHHHLGLAAIQRAAGHGVLFDTLTALENYPADGIPAL AGATGLGLEEITGRDATHYPLTFAAVPGERLALRVTHRPAAVTPARARELAGRVEHLLRV LVTAPDTRVAALDALTAAEHAELTADRAGPPAPAPRTWARLVAEQRDRRPDAVAVDAPDG SLTYAQLDLRARESAGTLRAAGIRPGQLVAVILPRSVDLVVAQLAVQQAGAAHLPIDPDY PEDRIAAMLQDARPAGILTHRALADRYPTALYTDAPPPAAAEASAATAPHPRHAPATDVT PDHPAYVIFTSGSTGRPKGVVTPHRGLTALAAAQAERLGIDDGSRVLQLASPSFDASVME TLMALATGATLVVPEPGPLAGPLLGETIARRRVSHALIPPTALTGLEPDGLDHLRTLIVG GEACTAPLTARWAPGRRMINAYGPTEATACVTMSAPLAPGATPPIGTPLHGVRVHVLDTL LRPVPPGGTGELYVAGPGVAQGYLGRPRLTAERFTAEPGGPRGSRMYRTGDLVSRTPEGS LLYHGRADDQVKIRGFRVEPGEIVAALQARPEIRAAAVVLRQDDPAGPRRLVAYLVPAAP SGGSRPEAGRLDTAALRTALARVLPDHMVPSAFVGVPGLPVTANGKLDRDALPAPDFGAA AGDTAPEGPAEETLAAIFAEVLGIPSVGAEDSFFTLGGDSILSMRLVARARAAGLRLTPR EVFELTSVRALAALASGREPDPAAGPAASALPDSGPAPLTPIMRWIAERPGPTGRFSQSM LLTLPPGITPAATAEVLGAVLRHHAVLRARIDLDAGTFVVPEPADGPAPALDEGPSATGA DPGALAREVDELATGLDPSQGLMVRARSYPGNAGEPGRLLLVVHHLAVDGVSWRILLDDL AQAWGDVSRGRAPHLPPATTSFRSWAHALGRQASARAGELPVWQGILAAPDRLPAPASGR AEPPALGTVADARHLVRTLDGAHTRTLLTGAAEHRGARVQDLMLTALARAVREWSGRERV DFAAHVEGHGREQQIEDGADLSRTVGWFTSLYPVRLAATAAEPPGDTLARTRDHLARLPD SGIGYGLLRYAAQPPAGLRPEETDGPGAPLIAFNYLGRFGTAPTGGGAAWAPAPGAGVLG GAVDAGLTMAHAVEINALTRDTPEGPLLDTRLTWAPAALDDRAAHALADCWQRALTALAA DAPPPPGPEPTTGPADPSAARPTDRPAHGLSPLSPEQTAKLEAQWRNR NT seq 17427 nt NT seq  +upstreamnt  +downstreamnt atgcgcatgagcacccaccgcgaacgcctgccgctgaccgaggcccagctcggtctctgg tccgcgcagcgaatcgacccggcgagccccgtgtacctcaccgcggagtacgtcgagttg acgggaccgctggacgagcgggcgttcgtggcggccgtgacccgggccgtcggcgaggcc gacggcctctccgtacgcttcaccgccgacggcgacgacgtccaccaggaaaccggcgcg atcccgccgacgggtcccggcctccacgacctgcgcacggccgaagacccgggcaccgcc gccctggactggatggaggaggaacgcaccgccccggtcgacatggagcacggcgcgctc taccggcacgcgctcctgcgcaccggcgacgagcgctggctgtggtaccaccgctgccac cacatcctgctcgacgcctacggttacgcccgcgtcgccgaacgcgtcgccgagctctac ggccacgcgtgcgcgggcaccgaaccccccgcgtccccgttcgccccgctgcgcgacgcg gtccaggaggaccggcgctacacggactccgaacagcacgccgccgacgcccggttctgg caggacctgctcgccgaccgcccgcacccgccgaccccggcccgcaccgcacccacccgc gtcgccccccgctccctgcgcagccgccgcaccctcggcgccgccgacgccgaacggctc gccgccttcgcccaacggtcccgtgccacctggcccgaggccgtgaccgccgcgtgggcg ctgtacctgacccgcctcaccggcacgcccgaagccgtcatcggactccccgtcagcaac cgcaccggcagcgtcctcgcccgcacccccgtcaccgccgtgaacgtcgtaccgctgcgg gtcgccgtcgacgaacgggagcccgtcggcgacctcctgcgccgtgtcaccgcgaccctg cgccgccagcgccgccaccagcgctaccggggcgagcgactccgccgcgacctccagctg ttcgggcacgggcggcggctcgtcggcccccagctgaacatcaagccgttcgccacggac ctcgccttcggcgactgcgcgggcacggtccactcgctggccgccggagccgtcgaggac ctcaacgtcacggtgggcggacggggcggcccggacggtctcaccggcctcgacctcgtg ctggacggcaaccccgacctgtacggacccgcggagctggacgcccacctgcaccgcttc gccaccctcctggaccggctctcccgcgcggagcccgatctccccggggcccgcgtcgga ctcctcgacgagcccgaacgcctgcgcgtcctggaggagttcaacgcccccgacgacggg gacgccgaagccgccccggcccccgacctcgtcgagggcttcacggaccaggcccgtcgc accccgcacgcggtggccctccgctgcggcgacgcccacctcacctacgcggagctggcc gaccgggccggccggctcgcatcggccctcacggcccggggcgcgggccggggcagcctg atcgccgtcgcccttccccggggcgaagcgctcctggtcgcgctgctggccgtggcgtcg gccggcgccgcatacgtccccctggacccgcgctacccggccgaccggctgcggcacatg ctggcggacagccgccccctcctcctggtcaccgaccgcgcccacccctggggcgcggat ctgccccggctcaccgtcgccctggacggaacactccccgacgcgaccccgggggccggt acggagtccctgtccgcgcccgccgacggcgtcccggcggggccgccccgttccggcgac ccggcggaccgccggccgggcgacccggcctacgtcatctacacctccggatccaccggc cgccccaagggcgtcgtcgtgccccgcccggccctcgccaacctcctggccgccatgggc cggctgctcgacctgtccggcgaggaccgcctgctcgcggtcaccaccgtctccttcgac atcgccgccctcgaactcttcgttccgctcctcgccggggccaccgtggtgctcgcggcc gacgacgacgtgagcgacccgttcgcgctctcggcgctcatccggtcgagcgcgcccacc gtgatgcaggccaccccctcgctctggcgcgtcctcgccgaggcggcccccgacgccctg ggcggcctgcgcgcgctcagcgggggagagccgctgcccgccgacctcgcggacgtcctg tcccggcacgcgaacggcctcgtcaacctctacgggccgaccgagaccaccatctggtcc accgcggccgtcctccaccggggcacaccgccgcacgtcggccggcccgtgcgccgcacc cgcgcccacgtcctggaccgcaccctcgcccccgcccccgtgggggtcaccggggaactg cacctcgcgggtgacggggtcgccgacggctacctcggccgccccgccctcaccgcgacg cgtttcgtcgccgaccccttcggggcgcccggcgcccggatgtaccggaccggcgacctg gcccggtaccgcgacgacggcacactggaagtgctgggccgcgccgacagccaggtgaag atccgcggccaccgcgtggagcccggcgaggtcgaggccgccctgctggcacacccctcg gtcgcggaggccgcggtcgccgccgtccccgcgccgggcggcgacctgacgctcgccgcg tactgcgtgctcacgcgtacggggaaggagcccggcgcgggggcggcgggcgagggcgat tgggccgacccgctgcgccacgcgctcgccgagcggttgcccgagcacctggtgcccggg cacttcgtggcgctggagcggctgccgctgacgccgaacggcaagaccgaccgggccgcc ctgcccgccgtcgcccccgccgccgctcccggggccggacgcgccccgcgggcaggggcg gaggccctgctgtgcgacctgttcgccgcggtgctcggccggagcgaagcatcccccgac gacgacttcttcctcctcggcggccactcgctgtccgcggcccgactggtgacggccctc cgctcccgcaccggcgtcgaactgcccgtacgggccctgttcgaccaccccaccccggcc cggctggccgacgccctggagcgggtggggggccttgaggggcccggccggaccgccggc gcgccgccgctggtccggcggccccggcccgcgcgaccgcccctctccttcgggcagcgg cggctctggttcctcgcccgcagccagggcgaggacggctcgtacaacatccccctcgcg atcgacgtcgcggcccggctcgacccggccgcactgcgccgcgcgctcggtgacgtcgcc gcccgccacgagatcctgcgcaccgtgctccccgtcgaggacggggaggcctggcagcag gtgctggacatcacggcggcggagcccggactggccgaagcccacgtgcgggaagcgcgg ttgggcgagcgcgtcagggcggaggccgccaggccgttcgacgtcgaacgcgaaaccccg ctgcgtgccgtgctgttcaccgtggagccggatcccgccgaaccgggctctgccgaaccg gggccgtgcggggcggagaccgtcgcgccggtccggcagaccctgctgctcgtcctgcac cacatcgccgccgacgaatggtcgctgccgctcctcctcgacgacctcgccgccgcctac gccgcccgcctggacggcagcgacccccacccgccgcggctgcccgtggaccacatcgac ttcacgctctggcagcaggacctcgtgaccgcgcgccaggaagctgacgcccagttctgg cgcacccggatgcggggagcccccgaacagctgaccctgccctgggcccggccccggccc gcccgcaccggcggccccgcccgcacccacgacttcggcatcgacgccgaactccaccag cgggtcaaggccttggcccggcgcacccgcaccaccaccttcatggtgctgcacgccgcg ttcgccgccaccctctcccagctcggctgcggcgacgacctcgtcatcggcacccccgtc gcggggcgcgacgacgaggcgctccgcggcagcgtcggcttcctcatcaacacccttccg ctgcgcacccgtctggacgccacgaccggcttcctcgacctgctggagcggaccagggac gacgacctcgccgccctcgcccaccggagcctcccgctggagcgcatcgtggcggaggtc aacccgccccgactgcccggcgtgagcccgctgttccaggtgctgttcgccgtacgggag gagttccccgaccgggccgtgctgcccggccagaccggccggccccgtctcgtcgcgacc ggggccgccaagttcgatctccagtgcaccgtcagcgaggacccggcgaccggtgcgacc gggcagctcgaataccgcaccgagctgtgggacgccgccgcggccgaccgcttcgcccgg gcgctgctgcacgtcctggaccagctcaccgcccatcccgagcgccccgtcgccaccacc cccaccggggccgggggagcggtcgcggcaccggagccgcaccccgtcccggccacctcg ctcgccgagctgtgcgccgcccaggccgcccggacccccggccgaaccgccctggtcagc ggagcggacgagatcacccacgcggacctcgacgcgcggtccgcccggctcgcccggctg ctggccgaccgcggggccggccccggcgccctcgtcggcgtcagcctgccccggggcgcc gacctcctcgtcaccctgctcgccgtcgcccggaccggggccgcccacctccccgtcgac cccggcttccccgccgagcggatccggatgctgctggccgacgccgcaccggcgctcctg gtcaccgaccgcgccaccgcccgcaccctcgacgcggacccgcgcagcgtcctcctcctg gacgaccccgcgacggtgcgcgccgccgccggggccgccccgctcgcgccccgggccgcc cacggtgacgcacccgcctacgtcatccacacctcgggctccaccggccgccccaagggc gtggtcgtcacccgggccgccgtcgtcaacttcctgctctgcctggccgacaccctgcgg ttccacggccgcgaacggctcctcgcggtgaccaccgtcggcttcgacatcgccgtcctc gaactgttcctgccgctggtcaccggcgctacggtgatcctcgccgaccgggaacaggtc cgcgaccccgcgctcctcgcggaactgatcgacaccgcccgccccaccgccatgcaggcc accccctccctgtggcgggccctcctggacaccgcccccgacgcggtgcgcgggctgctc gccctcgccgggggcgaggccctcgcccccgacctcgcccggcggctcgtcgcccacggc gctgacctcgtcaacctctacggccccaccgagaccaccatctggtccaccgccggccgc ctcgacgcgacggacgccgaggccccgcacgtcgggacgcccctgtggaacacccgcgcc ctggtcctcggacggggtctggtccccctgcccgtcggggtgaccggcgagctctacctc gcgggcgacggcctggcccagggctatctgggccgcccgggacagaccgccgagcgcttc accgccgacccctgcggcccgcccggcagccgtatgtaccgcaccggcgacctcgcccgg ctgcgcgccgacggcgccctggagatcgtcggccgcgccgaccaccaggtgaagatccgc ggccaccgcgtcgaacccgccgaggtcgccgccgcactccgcgcccaccccgccgtcgag gacgccgccgtcgtcgcccaccgcggccccgccgacccggcgccccggctgatcgcccac ctcaccggactcaccggctcccccgaggcccggaccgccaccgccgcccggatccgcgag gagctgcgcgccgtgctccccggccacctcgtaccggacctctgcctgccgctcgacgcc ctgccgctcaccccgaacggcaagctcgaccgggccgccctccccgcaccccggcccgcc gccgcacccgtcggacgcgccccggccgggcagggggaggaactgctcgccgcactcttc gccgacctgctcggcctcgaacaggtcggcgcggaagccgacttcttcgccctcggcggc cactccctgctcgccgcccggctcgcggtccgggccgccgaggcgctgggccggccgctc tccgtccggcagatcttcgacaccccgaccgtcgccgcgctcgccgcccggccggcggcc ccggagaccgccctgcccgccctcgaacccgtgccccacgaggggccgttgccgctctcg cccgcccaggcgaggctgtggttcctgagccggctccagcccggcaccgcctaccacctg cccttcgtcctgaccctcaccggggacgtcgaccacgacgccctggccgccgccgtcggc gacctggccgaacggcacgccgtgctgcgcaccgtgttccccgcggccgacggggcgccc gtccagcacatcctggaccggcccgaaccggtccgccgcaggaccgcccggagcgccgag gaagcggaggagctgctcggcgcactcagcgccgagcccttcgacctggctgccgaaccg cccttccgggccaccgtgctggccgaaccggaccggacgagggtcctgctgctgatccat cacatcgcggccgacgaatggtccgtggaacccctgctcaccgacctgtccgccgcctac cggacccggctcgccggagggccccccggcctgccgccgctcggcgtcgcctacacggac tacgcccactggcagcacgccctcctggacggcggacacctcgacggtcaggccggcttc tggcggcggacgctccgaggcgcacccgccgtcctcgacctgcccaccgaccgtccccgg cccgaaacccccaccggccgcggcggattcgtccccttcgccctgcccgacgaggtcgcc tccggtctgcgcgccctggccgccgacgccgcagtgaccccgttcatggtcacccaggcc gcgctgtgcgccctgctcgccgggctcggggccggggacgacatccccctcggcgtcccc accgcaggccggggcgaacggcgcacggaggagctgatcggcttcttcgtcaacaccctc gtcctgcgcaccgacctgtcgggcgacccgaccttccgtgaactcctcgcccgggtcagg gcggtggacctcgacgcgttcgaccacgccgaactgcccttcgagcgggtcgtggaggag ctcaaccccgaacgcggcccggccaacccgctgttccaagtgatgctgacgtaccagaac cgcacctcggtccccttcaccgcacccggcgtcgacgccgcgttcaccctgcgggagacg gacaccgcgaagttcgacctcatcgtcggtttcaccgaccacctcgccgacggctccgtc gacggggcgatcaactacagcgcggacctgttcgacgccaccaccgtccgggcgctcgcc gaccggctggtggccttcctcgcccgcgcggtcgcccgtcccgacacccgcatcggctcc atcgggctcctgaccgcgggggaggaggacaccctcctgcgccggtggaacccggccggc gaccaccggggcgcccccccggtcctcgaccggttcgcccgcgccgccgccgaccacccc gcggccccggcgctcaccgatgggggcgacaccctcacgtacgccgaactcgacgcccgc accaacgcgttggcgcgcctgctgatgtcgtacggggtcggacccgaggaccgggtcgcc ctgctgctgccccgctcggcgaccctcgtggaagcggtactcgccgtcgccaagaccggg gccgcctacgtccccgtcgacccggcccacccccgggaccgcatcgcctggaccctgcgg gacgccgcccccgccctcgtcgtcaccgacagcgcgaccgccggccgcacccccgccacc tgcaccgcgcccgtcatcgtcctggacgaggagccccatgcggggagtcggctccggcag ccggacggcccggtcgccgacgccgaacgcaccggcccgcagcgccaggacaacgccgcc tacctcatctacacgtcgggctccaccggccgccccaagggcgtcgtcgtcaccggccgc aacctcgcccgcctcttcgacgccaccgccgaggacgccttcggccccgacgacgtctgg accctcttccacagctacgccttcgacttctccgtctgggagatgtggggcgccctcctg cacggtggccgcctcgtcatcgtccccggcgccgtcacccggtccccggacgaattcctg gagctgctgcaccacgagggcgtcaccgtcctcaaccagaccccgtccgcctgctaccag ctcaccgaggccctcaccgcccccggttcccccggcctcccgcccgccctgcgcctcgtc gtcctcggcggcgaggcactcgaccccgcgcgcctcgcgccctggctccgggaccccgaa gggccccggctggtcaacatgtacgggatcaccgagaccaccgtgcacgtcaccacccac gacctcgcccccgggaccccggccccgggcgcgagccccgtcggccgggccatcgacgac ctgcgcgtctacgtgctggaccggcgtctgcgccccgtcccgcccggggtcggaggcgag ctgtacgtcgccggggccgggctctcccgcggctaccgcggacgccacccgctgaccgcc gaacgcttcgtcgccgacccgttcggcgcgcccggcacccgcatgtaccgcagcggcgac ctggcccgctggtccgccgacggcgtcctccactacctcggccgggccgacagccaggtc tccctgcgcgggttccgcgtcgagaccgccgagatcgagaccgtgctgcgcgacccgggc ggggcacgctccgccgccgtcctcctccgtgaggacctgcccaccggacccggcctcgtc gcctacaccacgggcgggaccccggccgacgcgctgcgggccgcctgcgcggcccggctg cccgcgtacatggtgccgaccgcgttcgtcgccctcgaccggctgccgctgaccaacaac ggcaagctcgaccgggccgccctgccgctgccggacaccgccccggacggaccgcccacc ggacgcgccccccgtaccccccacgaacacctcgtcgcccggctctacggcgaggtcctc ggccgggcccccgtcgccgccgacgaggacttcttcgccctcggcggccactccctgctg gtcacccggctcgccggacgcgtccgcgccgaactcggcctcgacgtccccgtccgcacc ctgttcgaagcccccaccgtcgccgcgctcgccgcccggctcaccggactcacccgcacc caggacgcccgtgtccccggcccggcgccggccgccgtacgccccgaacggctcccgctg tcgcccgcccaggcccggctgtggttcctccaccggctcggcggatccgcgctcacctac gccgtaccgctgctgctgcggctgcgcggccccctcgacgagagcgccctcggccgcgcc ctcgccgccctcgcccgacgccacgagatcctgcgcacctgctaccccgaacacgaggga cgcccggtccagcaggtgctgcccgaggccgcccccgtacccctggcgagcgcgctgctg gacggcgagagcgcccaggacgcggcgcggcggctcgcggccgagcccttcgacctggcc gaccggcccccgctccgcgcgcatctgctcaccggacccggcgacgagcggtccctgctg ctcctggtccaccacatcgcctacgacgaagcctccaccgggccgctcgtccgggacctc gcccggctgtacgccgccgaactcgacccggaccacggggcgcccgagccccccgccctc cagtacgccgactacaccctctggcaccgggaggcgaccgcggcccgggaggacgggctg ctggcctactggcgcaccgcgctcgccggagcccccgaggagacctccctcccgctggac cggccccggcccgcggaggtcgacgaacacggggactccgtcgagttcaccgtccccgcc gacctccaccgggccgccgcccgcctcgcccgcgacaacggcgccaccctgttcatggtg ctccagtccgccctcgccgtcctgctcaccggacacggagcgggccacgacctgccgatc ggcaccctgctcagcggccggggcgagagagcgctggaggaactgcccggcctgatcgcc aacaccgtggtcctgcgcaccgacacctccggcagccccaccttcaccgaactcctcgcc cgggtccgcgcggtcgacctcgacgccttcgaccacggcgacctgcccttcgagcggctc gtcgacgccctcgccccgcagcgctccctctcccgccacccgatcttccaggtcgccctg atccaccagaacgccccgcaccgcaccctccccttcgggccggccaccgtcgaggcggaa ctggtcgagacccgcgccgcgaagttcgacctgaccctcgccgtcgtcgaggaacccgga acggacgggctgcgcgccgctctcaactaccgcacggccctcttcgaccgcccgaccgtc gaggccctcgcccaccggctgaccaccctgctccaccggctctgcacccaccccggcctc cccgtcgaccaggtgcccgtcctggacgaggcggaggcacggcgggtgctcaccgcctcg gccggcccccacgtcccgctgcccgggcgcaccctcgtcgacctggtacgcgaacaggcc gcccggtccccggccgccgaggccctgcgcgacggaacccgcagctggagctaccgcgag ttcgacacggaggccgaccggctcgccggactcctcgccgaacacggcgtccgacgcggc gacaccgtggtcgtcgccgtgccccgctccgccgaactcgtcctcgccgtccacgccgtc cagcgcgccggggccgcctacctgccggtcgaccccgcccagccggccgcgcgcgtcagc tcccaactccaggacgcggaagcggtcctgctgatcacggaccccgccgccgccctgccc ggggaagccgtcggcggcctgcccgtactcgacgtcaccgcagacgaggtgccccgcttc accaccgtcctcgacgggccccgccccgccgaccccgcctacctcctcttcacctccggc tccaccggccgccccaagggcgtccgcgttccgcacgacgccgtggccaaccggctccgc tgggcccaggacgcctaccggctcaccgaggaggaccgcgtcctcctcaagaccccggcg accttcgacgtatccgtctgggaactcttctggccgctgctcgccggcgccaccctcgtc accgcgggacccgacgaccaccgcgacccggtcgccatcgcccggctcctgcgcgaacac cgcgtcaccaccgtccacttcgtgccgtcgatgctcgccgccttcaccggcaccgccgcc cccgccgactgcgcgaccctccgccgcgtcctcgcgagcggcgagaccctcaccccggcc gccgccgcgggactgctgcgactcgccccgggcgccgaactgcacaacctctacgggccg accgaggcggccgtcgacgtcaccgcccaccccgtcaccgccgccgacatcgcctcggga cgcctccccatcggccgcccggtgtggaacaccaccaccctcgtcctggacgcgcggctg cgcccggccccgcccggcgcggccggcgagctctacctcgccggagcccaactggcgtac ggctaccaccgccgcgccgccctcaccgcgacgcgcttcgtcgccgacccgtacggcccg cccggcagccgtctctaccgcaccggcgacctggcccggctgcgggccgacggggcactg gagcacctcgggcgggtcgacgaccagatcaagctgcggggccagcgcgtcgagcccggc gagatccgcgccgtgctcgacgcccaccacgggatcgccgcagccgcggtggtggcccac gaggacaccgccaccggcgtcacccacctgatcggctacgtcgtcccccggacgggggag ggcgcggcgctccccgccggtctggcggaacacctcgccgcccggctccccgcccacctc gtccccaccgccctcatcccgctgcccgccctgcccgtcaccgccaacggcaagctcgac cgcgccgcgctcccggccccgcgcctcacctccccggagacccggaccgcaccccgcacg gacgaggaactgcggctcgccgccctcttcgccgaactcctgcggaccgagcacatcggc gtcgacgacagcttcttcgccctcggcggcgacagcatcctgtccatccagctcgtcgcc gcggcccgcaaggccggactccacttcaccccccaggacgtcttccgccaccggaccgtc gccggcctcctcgccgtcgccgaacccaccaccccggcggccccgccccgcgccctgccc gccgcaccggacgacggggcccccggccggcccaccccgctccaggaaggactgctgttc ctctcccagtacgacggcccggggtccacgggcgccggtgacccgctcgacgtctaccac gtccaggtcgccatccgtctcaccggagacctcgacaccgaccgcctgcgcaccgcgctg cgcaccgtcgtccgccgccacgcgcccctgcgcaccgcgttcaccggagacgggaacggc tggacccagcgcgtgcacaccgaccccgagccggagttcgccgtcctggacctgcgccgc cgcaagcccagggaacaggagcgccgcgccgcccggcgggccgacgacgagcgccgccgc cgcttcgacctctccgccccgccgctgctgcgcgccacgctcgtccgacgcccggagacc tgcgaactcgtcctcaccggacaccatctggtcctcgacggatggtcgttgcccctcctc gtccgcgaactcctccacacctacgcggaacgggaactgcccgaaccgccggactacgtg ctccaccgcgcctggctcgacgcccgggacgagcagagcgctgccgaggcctggcgcgac gcgctggacggtgtcaccgagcccacccggctcgtccccgacgaccccggtgagcaggaa ctccccgaccagcagacggtgtgggtcgacgccgaactcaccgagcgcatcgcggcgttc ggccgggaacgggaactgacgctgagcaccctcacccaggccgcctggggcctggtgctg agcgcccacacgggtcggcgcgacgtcgtgttcggcacggtcgtctccggccggcccgcc gaggtgcccggtgcgacggagatgatcggcctgttcgtcaacaccgttcccgtacgcgtc accgtgcgcccccaggagacgctcgccgctctggcggcccgcctccaggacgagttcacc gccctgctgccccaccaccacctgggcctggccgccatccagcgggcggccggacacggt gtcctcttcgacaccctcaccgccctggagaactacccggccgacggcatccccgcgctc gccggggccaccggcctcggcctggaggagatcacgggccgggacgccacccactacccg ctgaccttcgccgccgtgcccggcgaacggctcgccctgcgcgtcacccaccgccctgcg gccgtcaccccggcacgcgcgcgggagctcgccggacgcgtcgaacatctgctgagggtg ctcgtcaccgccccggacacccgcgtggccgccctggacgccctgacggccgccgaacac gcggagctcaccgcggaccgcgccgggccgccggcccccgcgccccgcacctgggcccgg ctcgtcgccgaacagcgcgaccgcaggccggacgccgtggccgtggacgcgccggacggc tccctgacctacgcgcaactggacctgcgggcgagggaatcggccgggacgctgcgcgcg gcggggatcaggcccggacaactcgtcgcggtgatcctgccgcgctccgtcgacctggtc gtcgcccagctcgccgtccagcaggcgggcgccgcccacctgcccatcgacccggactac cccgaggaccgcatcgccgcgatgctccaggacgcccgtccggcggggatcctcacccac cgggcgctcgccgaccgctacccgacggcgctgtacacggacgcgccgccgcccgcggca gcggaagcctccgccgcgaccgccccgcacccccgccacgccccggccacggatgtcacc cccgaccaccccgcctacgtcatcttcacctccggttccaccggacgccccaagggcgtg gtcaccccgcaccggggcctcaccgccctcgccgccgcccaggcggaacgactgggcatc gacgacggcagccgggtcctccagctggcctccccgtcgttcgacgcctccgtgatggag acgctgatggccctggcgaccggcgccaccctcgtcgtcccggaaccgggtccgctcgcc ggaccgctcctcggcgagacgatcgcgcggcgccgcgtcagccacgccctgatcccgccc accgccctcaccggcctcgaaccggacgggctcgaccacctgcgcaccctgatcgtcggc ggcgaggcgtgcaccgcgccgctgaccgcccgctgggcacccggccgccgcatgatcaac gcctacgggccgaccgaggccaccgcctgcgtcaccatgagcgcgcccctggcccccggc gcgaccccgcccatcggcaccccgctgcacggcgtccgcgtccacgtcctggacaccctg ctccggcccgtgcctcccggcgggaccggcgaactgtacgtggccggacccggcgtcgcc cagggctacctgggccgtccccggctcaccgccgaacgcttcaccgccgaacccggcggc ccgcggggcagccgcatgtaccgcaccggcgacctggtgtcccgtaccccggagggctcc ctgctctaccacggacgcgccgacgaccaggtgaagatccggggcttccgcgtcgagccg ggggagatcgtcgccgccctccaggcccgaccggagatccgcgcggcggccgtcgtcctg cgccaggacgacccggcgggcccgcgccggctggtcgcctatctggtacctgccgcgccg tccggcggcagccggcccgaggcggggcgactcgacaccgccgccctgcgcaccgccctc gcccgcgtcctgcccgaccacatggtgcccagcgccttcgtgggcgttcccgggctgccg gtgaccgcgaacggaaagctggaccgcgacgcgctgcccgcccccgacttcggcgcggcc gccggcgacacggcccccgaagggccggccgaggagacgctggccgcgatcttcgcggag gtgctggggatcccgtcggtgggcgcggaggacagcttcttcaccctcggcggcgacagc atcctctccatgcgactggtggcccgcgcccgcgccgcgggcctccgcctcaccccgcgc gaggtcttcgaactgacctcggtccgggcgctcgccgcgctggcctccggccgggagccg gacccggcagccggaccggcggcctccgccctcccggacagcggccccgcgcccctcacg cccatcatgcggtggatcgccgaacggcccggccccaccggcaggttcagccagtccatg ctgctgaccctgccgcccgggatcaccccggcggccacggccgaggtgctgggcgcggtc ctgcgccaccacgcggtcctgcgcgcccgcatcgacctggacgccgggaccttcgtggtc ccggagccggccgacgggcccgccccggccctggacgagggcccctccgccacgggcgcc gaccccggggccctggcccgcgaggtcgacgaactcgccaccgggctcgacccgtcccag gggctgatggtgcgggcccgcagctatccggggaacgcgggagagccgggcaggctgctg ctcgtcgtccaccacctcgccgtcgacggcgtctcctggcgcatcctgctcgacgacctg gcccaggcctggggcgacgtgtcccgggggcgcgccccgcacctgccgcccgcgaccacc tcgttccggagctgggcccacgcgctgggccgccaggcgtccgcgcgcgcgggcgaactg cccgtctggcaggggatactggccgcacccgaccggcttcccgcaccggcctccggccgc gccgaaccgcccgccctgggcacggtcgccgacgcccgccacctcgtccggaccctggac ggcgcgcacacccgcaccctgctcaccggagccgccgaacaccgcggcgcccgcgtccag gacctcatgctcaccgccctcgcccgcgccgtgcgcgagtggagcgggcgcgagcgggtg gacttcgcggcccacgtcgagggccacggccgggaacagcagatcgaggacggcgccgat ctctcccgtaccgtcgggtggttcaccagcctctaccccgtacgtctggccgcgacggcc gccgagcctcccggggacaccctcgcgcggacccgcgatcatctggcacgccttcccgac agcgggatcggctacggcctgctgcggtacgcggcgcagccccccgcgggtctccgtcct gaggagacggacggccccggcgcccctctgatcgcgttcaactacctggggcgcttcggc acggcgccaaccggcgggggagcggcctgggccccggcgcccggggccggcgtgctcggg ggcgccgtcgacgcggggctgaccatggcgcacgcggtcgagatcaacgccctcacccgg gacacccccgagggccccctgctcgacacccggctcacctgggccccggcggccctcgac gaccgggcggcgcacgccctcgccgactgctggcaacgcgcgctgaccgccctcgcggcg gacgccccgccgccccccgggccggagcccacgaccgggccggccgacccgtccgcggcc cggcccaccgacaggcccgcccacggactgtccccgctcagccccgaacagacagccaag ctcgaagcacagtggaggaaccggtga

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