Streptomyces griseus: SGR_5417
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Entry
SGR_5417 CDS
T00691
Name
(GenBank) putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sgr
Streptomyces griseus
Pathway
sgr00300
Lysine biosynthesis
sgr00550
Peptidoglycan biosynthesis
sgr01100
Metabolic pathways
sgr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sgr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SGR_5417
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SGR_5417
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SGR_5417
Enzymes [BR:
sgr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SGR_5417
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
APH
PhageMin_Tail
DUF561
Motif
Other DBs
NCBI-ProteinID:
BAG22246
Kitasato:
SGR5417
UniProt:
B1W0I6
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All DBs
Position
6369843..6371264
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AA seq
473 aa
AA seq
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MITLSLAEIAEIVGGQSYDIPDPAVTVTGPVVIDSREVAPGSLFAAFAGERVDGHDYARR
AVEAGAAAVLAARPVGVPAIVVEDVVGALGALARAVVERLGTTVVGLTGSAGKTSTKDLI
AQLLQRKGPTVWTPGSLNNEIGLPVTALTATAETEHLVLEMGARGIGHIRYLADLTPPRI
GLVLNVGSAHLGEFGSREAIAQAKGELVEVLPEDGCAVLNADDPLVRAMASRTRARVLLF
GEAPEADVRGEKVRMTADGRPAFELHTPTGCSDVTMRLYGEHHVSNALAAAAVAHELGMS
VTEIAEALSEAGTLSRWRMEVTERGDGVTIVNDAYNANPESMRAALRALAAMGQARGADG
GRTWAVLGQMAELGDASLAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEE
SVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLEKVAQALLENSTEGEVAGR
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
gtgatcaccctttccctcgccgagatcgccgaaatcgtcggcgggcagtcgtacgacata
ccggatccggcagtcaccgtgaccggacccgtcgtcatcgactcccgcgaggtcgcgccg
ggcagcctgttcgccgcgttcgccggcgaacgggtcgacggccacgactacgcccggcgc
gccgtcgaggcgggcgccgcggccgtcctggcggcccgccccgtcggcgtcccggcgatc
gtcgtggaggacgtcgtcggcgccctcggagccctcgcccgtgccgtcgtggaacgcctc
ggcaccaccgtcgtcggcctcaccggatccgccggcaagacgtccaccaaggacctgatc
gcgcagctcctccagcgcaagggcccgaccgtctggacgcccggctccctcaacaacgag
atcggcctgccggtcacggcgctgaccgccaccgccgagaccgagcacctggtcctggag
atgggggcccgcggtatcggccacatccgctatctggccgatctcacccctcctcgcatc
ggtctcgtcctgaacgtcggctccgcgcacctcggcgagttcggcagccgggaggccatc
gcccaggccaagggcgagctggtcgaggtcctgcccgaggacggctgcgccgtgctcaac
gccgacgacccgctcgtccgcgccatggcttcgcgcacccgggcccgcgtcctgcttttc
ggagaagccccggaagcggacgtacggggcgagaaggtcaggatgaccgccgacgggcgg
cccgccttcgagctccacacacccaccgggtgcagcgacgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagttgggcatgtcc
gtgaccgagatcgccgaggcgctctcggaggcgggcaccctctcccgctggcgcatggag
gtcaccgagcgcggggacggtgtgacgatcgtcaacgacgcctacaacgcgaaccccgaa
tccatgagagccgcactgcgtgcgctggccgccatgggccaggcccgaggggccgacggg
gggcgcacctgggcggtgctcggtcagatggccgagctcggtgacgcgtcgctcgccgag
cacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtcgctgtcggg
gggagagaagcctcctggctgcaactgggcgcatataacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcacaggcggccgtcgacctgttgcgcagtgaactgcgcccg
ggagacgtcgtgctggtgaaggcgtcccggtcggtcggcctggagaaggtcgcccaggca
ctgctggagaactcgaccgagggcgaggtcgccggccgatga
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