Schistocerca gregaria (desert locust): 126335019 Help Entry 126335019         CDS       T08688                                  Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism sgre  Schistocerca gregaria (desert locust) Brite KEGG Orthology (KO) [BR:sgre00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sgre04040]     126335019    04990 Domain-containing proteins not elsewhere classified [BR:sgre04990]     126335019 Ion channels [BR:sgre04040]  Voltage-gated cation channels   Ryanodine receptor    126335019 Domain-containing proteins not elsewhere classified [BR:sgre04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    126335019 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 EF-hand_5 EF-hand_1 SPARC_Ca_bdg Motif Other DBs NCBI-GeneID:  126335019 NCBI-ProteinID:  XP_049853805 LinkDB All DBs Position 2:776458605..777149853 Genome browser AA seq 5136 aa AA seqDB search MADSEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCYLETIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETEQESLGKGTGSGHRTLLYGNAILLRHQNSDMYLA CLSTSSSNDKLAFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYL HTTKENDLSVVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTW SEQPGQNIVIYEGGSVMSQARSLWRLELARTKWAGGFINWSHPMRIRHLTTGRYLGVNEN NELCLVTRDEATIASSTFCLRQEKDDQKVVLEDKDLEVIGSPIIKYGDSTVIVQHSETSL WLSYKAYETKKKGVGKVEEKQAVLHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTKF ITGLETLQTNRRHSLFFMSVNLNEMVMCLEDLINYFAQPEEEMEHEEKQNRLRALRNRQD LFQEEGILNLILEAIDKINVITSQGFLIALSGDDTGQSWEVISGYLYQLLAAIIKGNHTN CAQFANSNRLNWLFSRLGSQASSEGTGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEK HGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDHVASVRPNIFVGR VEGSAMYQKWYFEVTLDHIEQTTHMTPHLRIGWANTSGYCPYPGGGEKWGGNGVGDDLYS YGFDGAYLWTGGRKTHVLNNTNEPYIKKGDVVGCAFDLTVPVITFTFNGHKVKGSFRNFN LDGMFFPVISCSSKLSCRFLLGGDQGRLKYIPPEEFSPLVESLLPQQVLSIDPCFYFGNL NKCVLSGPWPVEDDTAFVPTPVDTSMITLPGYIESIRDRLAENIHEMWAMNKIEAGWAYG ERRDDVRKIHPCLIQFERLPPAEKRYDSQLAVQTLKTILALGYYITMDKPPSRIKTVRLP NEPFLQSNGYKPAPLDLSAITLTPKMEELVDQLAENTHNLWAKERIQQGWTYGLNEDPDM RRSPHLVPYIKVDEAIKKANRDTASETVRTLLVYGYNLEPPTGEANEALLAEANRNRQTR FRTYRVEKNYAVSSGKWYFEFEIMTAGPMRVGWARADCSPGCQLGSDETTWAFDGYNEVK YNCGQAETFGKQWQVGDVVGVFLDLVDRTISFSLNGELLMDALGGETSFSDVQGDSFVPA CTLSVGQKAKLTFGQDVNTLKFFTTCGLQEGYEPFCVNMKRAVTYWYTKDQPIFENTDDM LDTKIDVTRIPAGSDTPPCLKISHNTFETMEKANWEFLKLSLPVICQSTFIEEGEKIRRW QEIKIRQHRLLAEADQTTPAHIEQIMKSGFTMSDIKGLQRGYSEDVVEADEIIMNGPTPD SPQSPSKLKNRPSRPPRKGSLSRNATYDNMENALTNGMLEPGKIHRSTSDMDLNRYNMDG MVNNQDAIRDDKKKRGRSPFRFFSRKRDASSEGMKKAKTPEPGGIDGEILPERNKPLGMA RTNTLQPPRTAQVRMSQTDLKVVPPSVPDRSPKALSVPAATGVEAIGNEIFDAECLKLIN EYFYGVRIFPGQDPTHVYVGWVTTQYHVHRKDFNQSHVQKASVTIVDEYERIMESVDRQS CYMVRADELYNEVTNDASGKGASQGMFIGCFVDAATGYVTFTCEGKETNHRFKMEPETKL FPAIFVEATSKEILQIELGRTSTTLPLSAAVLQNSERHVIPQFPPRLKVQCLKPHQWARV PNQSLQVHALKLSDIRGWSILCEDPVSMLALHIPEEDRCIDILELIEMERLLSFHAHTLT LYAALCYQSNYRAAHALCQHVDQKQLLYAIRSEYMSGPLRQGFYDLLIALHLESHATTME ACKNEYIIPLGQELKELYENPDMRHSLRSLKTESVRPQMKMTDIAETIENIRNLYSPDFP LDAVKDYIMAALDEAVQVNQVHNRDPIGGSNENLFLPLLKLVDRLLLVGLLTDEDVGKLL IMIDPETWDSSFDKEGKDEHRKGLLQMKMAEGAKLQMCYLLHHLCDSQLRHRVESIIAFS HDFVAELQTDQLRRYVDIKQSDLPSAVAAKKTREFRCPPKEQMNAILGFKNLEEEDKENC PCGEELRDQLNAFHEKLMSHVSLNALRDAEEAEENAVEVVKPGPIKRLYNFINAVKEMEE EPKEAVEPEKKTPEEIFRKVLIKTIVRWAEESQIETPKLVREMFGLLVRQYDSIGELIRA LQKTYVINSKTKNDVAAMWVGLSQIRALLPVQMSQEEEELMRERLWKLVNNHTFFQHPDL IRILRVHENVMAVMMNTLGRRAQAQSDTQTQAQATGQEGEVSAKEKDTSHEMVVACCRFL CYFCRTSRQNQKAMFDHFSFLLENSNILLSRPSLRGSTPLDVAYSSLMENTELALALREH YLEKIAIYLSRCGLQSNSELVEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLV IRLLIRRPECLGPALRGEGEGLLRAIIDANKMSERIADRRKVMDEAEGTMTVMQFEHPLP ESEDDEDYIDTGAAILNFYCTLVDLLGRCAPDSSVILQGKNESLRARAILRSLVPLEDLQ GVLSLKFTLQNPAAGEERPKSDMPSGLIPANKQSIVLFLERVYGIETQELFFRLLEEAFL PDLRAATMLDRNDGYESDMALAMNRYIGNSILPLLIKHSKFYNEADNYANLLDATLHTVY RLSKNRMLTKGQREAVSDFLVALTSQMQPSMLLKLLRKLTVDVSRLSEYTTVALRLLMLH YERCAKYYGTSFGQGMYGASSDEEKRLTMMLFSNIFDSLSKMDYDPELFGKALPCLTAIG CALPPDYSLSKNYDDEWYGSKDTSDPDGPYNPQPINTSSVVLNNDLNTIVQKFSEHYHDA WASRKLENGWAYGEQWSDSSKTHPRLKPYNMLNDYEKERYKEPVRESLKALLAIGWTVEH TEVEIPSNSRNSMRRSSKGGEQSSTPFNYNPHPVDMTNLTLSREMQNMAERLAENAHDIW AKKKKEELITCGGGIHPQLVPYDLLTDKEKRKDRERSQEFLKYLQYQGYKLHRPTRSGAG ESEQTTGAISVELRFAYSLLEKLIQYLDTASINMKMFKPSSTFSRRTSFKTSTRDIKFFS KVVLPLMEKYFSTHRNYFIAVATATNNVGAASLKEKEMVASLFCKLASLLRSRLAAFGAD VRISVRCLQVLVKSIDAKSLVKNCPEFIRTSMLTFFNNVADDLGHTIQNLQEGRYSHLRG THLKTSTSLSYINGVVLPVLTAMFDHLAACEYGSDLLLDEIQVASYRMLSSLYTLGIDAT LTHDRKYLKTELERHRPALGSCLGAFSSTFPVAFLEPHLNKHNQFSLLNRIADHSLEAQD VMARMEQSMPTLETVLSDVDQFVESDKSHADAPHIIDVILPLLCSYLPFWWAQGPDNVSP TGGAHVSMVTSEHMNQLLKNVLKLIKKNIGNESAPWMIRIAAYTQQIIINSSEELLKDPF LPLAEKVKKRTDTLFHKEESLRGFIKSATDDTSQIESQIQEDWHLLVRDIYAFYPLLIKY VDLQRNHWLRHNVAEAEDLYNHVAEIFNTWSKSQYFMREEQNFISANEIDNMVLIMPTAS RRSAVVSDVSQLGGGSKKKKKHRDKKRDKDKELQASLMVACLKRLLPVGLNLFAGREQEL VQHCKDRFLKKLPESEILEFAKIQLTLPDKIDPADEMSWQHYLYSKLGQKKNGEEGKPTK VEDVVERIVAMSKVLYGLHMQANKPKPSRDGWKRVLSAARKRAAIACLHSEPLHKLRRHR AINIYVRSYCDLWLQDENVGQEIMIEDLTQSFEDAELKKRDEQEDEGKPDPLNQLVTTFC RGAMTERTGALQEDPLYMSYAEIQSKSCGEEEEEGEEEGGDEEGAASIHRTMDKLMEQEM EKQKLLFHQARLANRGVAEMVLLHISACKGVPSEMVMKTLQLGISILRGGNSDIQMGMLN HLKEKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSEGAAGEKNMHDAEFTCAL FRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIID PAGKANFFKAIGVASQVFNTLTEVIQGPCTQNQQALAHSRLWDAVGGFLFLFSHMQDKLS KHSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDM FLKLKDLTSSASFQEIDINHDGWVTPREFREKMEQQKSYTIEEINFLLMCCDTNHDGKID YVEFTERFHNPAKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPYLGRIEIL GGSKRIERVYFEIKESNIEQWEKPQIKESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFE MTHASGLMASEESSTIGKAREASYSYMTEEDEERAAKDPIRRGIQAVKDAVYFSLALLSP TNIKNKINELQQMSFMELFVGFFKLIFYVFYYSGFGVSVVIKYVVGILMSLMRGPQIEEP VVEVKEEERMGPLRVLPALPATPDEANAPQQMQAFGLDITKEDNGQYHMVPHESAPPSPQ SSVEEGGDTTPEEGAEEHAKQEAAEGESPMSLVDLLGGDAARKAAAATAEAAVQQQAAMA AVEAESKQEVVVEPSAMSQIDFSEYTKRAVSFLARNFYNLKYVALVLAFCINFMLLFYKV TTLGGDDDENGNGSGEEVADLMEELSMEVNSTEVGSAENGSGEEEEPLELVHVDEDFFYM EHVLRLMALLHSMVSLAMLIAYYHLKVPLAIFKREKEIARRLEFDGLYIVEQPEDDDIKS HWDKLVISAKSFPVNYWDKFVKKKVRQKYSETYDFDSISNLLGMEKTSFSAQEEEGGSGL INFIANIDWRYQIWKSGVTITDNSFLYSLWYFTFSILGNFNRFFFAAHLLDVAVGFKTLR TILQSVTHNGKQLVLTVMLLTIVVYIYTVIAFNFFRKFYVQEEDEEVDKKCHDMLTCFVF HLYKGVRAGGGIGDEIEPPDGDDYEVYRIMFDITFFFFVIVILLAIIQGLIIDAFGELRD QLESVKEDMESNCFICGIGKDYFDKVPHGFDTHVQQEHNLANYMFFLMHLINKPDTEYTG QETYVWNMYQQRCWDFFPVGDCFRKQYEEELGGGGG NT seq 15411 nt NT seq  +upstreamnt  +downstreamnt atggctgacagcgaaggaggctccgagcaagatgatgtatcatttctccgaacggaagac atggtgtgcctgtcatgcacggccaccggtgagagggtgtgtctggctgccgagggcttc ggcaaccgacactgttacctggagaccatcgcagacaagaacatcccgccagacctgtcg caatgcgtgttcgtgatcgagcaagctctgtcggtgcgcgctctgcaagagctggtcacg gccgcgggatcggagacggaacaggaatcacttgggaaaggaacaggctctggccacaga accctactttacggcaatgccatactgctgcgacatcagaatagtgatatgtacctggca tgcctgtctaccagctcctcaaatgacaaactggcatttgatgttggtttacaggagcat tcacaaggggaagcctgttggtggacagtacaccctgcttccaagcaaagatctgaaggt gaaaaggtgagggttggtgatgaccttatccttgtctccgttgccactgagaggtacctg catacaaccaaagaaaacgatttgtctgtggtgaatgcctctttccatgtgactcactgg tctgtccagccatatggaacaggaataagcaggatgaaatacgtgggttatgtgtttgga ggcgatgttctcaggttcttccacggtggtgatgagtgtctcaccattccatcaacatgg agtgaacagcctggacagaacattgttatatatgaaggtggtagtgtcatgagtcaagcc aggtccctgtggagattggaacttgcaagaacaaaatgggctggtggcttcattaactgg tcccatccaatgagaataaggcacttgacaactggccgttacctcggtgttaatgaaaat aatgagctctgtcttgtcacaagggatgaagcaacaattgcatcatcaacattctgcctg cgccaagaaaaagatgatcagaaagtggtacttgaagacaaagatcttgaagtgattggc tcacccataataaaatatggcgacagcacagtcatagttcaacattcagaaacctcactt tggttatcatataaggcttatgaaacaaaaaagaaaggtgtggggaaagttgaagaaaag caagctgtcctccacgaagaagggaaaatggatgatggcttagattttagccgcagtcaa gaggaggaatcaagaacggctcgtgttataagaaaatgtagttcccttttcacgaaattt ataacgggactagaaacactgcagacaaatagacgacattcattgttttttatgtctgtg aatttaaatgaaatggttatgtgccttgaagatttaataaactactttgctcagccagag gaagaaatggaacatgaagagaagcagaacagacttagagcattgagaaacagacaggac ctgtttcaagaagaaggaatattaaacctcatccttgaagctattgacaaaattaatgtt atcacatcacaaggattcctaattgccctgtctggagatgatacaggccaaagctgggaa gttatttctggatatctgtaccagcttcttgctgccataataaaaggaaaccacacaaac tgtgctcagtttgccaactcaaatagactgaattggttattcagcagactgggttcacag gcatctagtgagggtacaggaatgctggatgtgctccattgcgttctcattgattcacca gaagcattgaatatgatgagggatgaacacattaaagttatcatatctttactagagaaa catggtcgagatccaaaagttcttgatgtgctgtgctcattgtgtgtgggtaatggcgtt gcagttagaagttcacaaaataacatatgtgacttcttgctccctgggaaaaatcttctt ctgcaaacacagcttgtggaccatgtagcaagtgttcggcccaacatattcgttgggcga gtagagggttctgccatgtaccagaagtggtactttgaagtaacactggatcatattgag cagacaacgcatatgacaccacatctgagaatcggatgggccaatacttcagggtattgc ccttacccaggaggaggtgaaaagtggggtggaaatggagtgggtgatgatctttattca tatgggtttgatggagcctacctgtggacaggtggaagaaaaacccatgtgctcaataat actaatgagccatacataaagaagggagacgttgtgggctgtgcctttgacttaacagta ccagtaataacattcacgtttaatggccataaggtcaaaggatcattccgaaattttaat ttagacgggatgttttttcctgtaataagctgttcttccaaactgagttgtcgatttcta cttggtggagatcaaggacgactgaaatacattccaccagaagaattttcacccctagtt gaaagcttacttcctcaacaagttctttccattgacccttgcttctactttgggaacctc aataaatgtgtgctttcaggaccatggccagttgaagatgatacagcatttgtgccaacg ccagttgacacatcgatgattacattaccgggctatatagaaagcatcagagatcgtctt gcagaaaacatccatgaaatgtgggcaatgaacaaaattgaagccggatgggcatacgga gaaaggagagatgatgttcgtaaaattcatccatgcctcattcagtttgaaagactgcct ccagctgagaaacgttatgattcacagcttgcagttcaaacactaaagacaattcttgca cttggatattatattaccatggacaagccaccatctcgtatcaaaactgttcgtcttcca aatgaaccattcctccagtcgaatggctacaaaccagcacccctggaccttagtgctatc acacttactccaaaaatggaagagttggttgatcagcttgcagaaaatacacacaatctc tgggcaaaagaacgcattcaacaaggctggacttacggcctcaatgaggatcctgatatg agaagaagccctcacctggtgccttacataaaagtggatgaagcaatcaagaaagcaaat agggatactgcaagtgaaacagttcgcacattgcttgtatatgggtacaatttagagccc ccaactggagaagcaaatgaagctttgcttgctgaggccaatagaaacagacagactcgt ttcagaacatatcgtgttgagaagaattatgctgtttctagtgggaaatggtactttgaa tttgagataatgacagctggtcccatgcgtgttggctgggctcgagctgactgtagtcca ggctgtcagcttggaagtgatgaaactacatgggcatttgatggctacaatgaagtgaag tataattgcgggcaagccgagacgttcggcaaacagtggcaagtgggagacgtggtcgga gtcttcctcgatcttgtagatcgaactatcagtttctctcttaatggtgaacttctgatg gatgcacttggaggagaaacatctttttcggatgtgcaaggagattcatttgttccggca tgtactttaagtgttggacagaaagctaaattgacatttggtcaggatgtcaatactctg aagttcttcactacatgtgggttacaggaaggctatgaaccgttctgtgtaaacatgaag agagctgtaacttactggtacaccaaggatcaaccaatatttgaaaacacagatgacatg ctggatactaaaatagatgttactcgtattcctgctggttcagacacacccccgtgtctg aagataagtcacaatacatttgagactatggaaaaagccaactgggaattcttgaaactt tcactgcctgtcatctgccagtcaactttcatagaagaaggtgagaaaattaggcgatgg caagaaataaaaatccgacaacacagattactcgctgaagctgatcagacaacaccagct catattgaacagataatgaaatctggatttacaatgagcgatattaaaggtctccagcga ggttattcagaagatgttgtagaagcagatgaaattattatgaatggaccaacacctgat tcaccacaatcacctagcaagcttaaaaatagaccatctagaccaccacgcaaaggctcc ttgtcaagaaatgctacttatgataacatggaaaatgcattgacaaatggaatgttggag ccaggtaaaattcataggtcaacaagtgatatggatctaaatagatacaacatggatggg atggtaaataaccaagatgctatccgagatgacaaaaagaagagaggtcgttcaccattc agatttttctcccgaaaacgagatgcaagcagtgaaggaatgaagaaagcaaaaactcca gaaccaggtggtatagatggggaaatactaccagaaagaaataaaccacttggtatggca cgtacaaatacacttcagccaccacgaacagcacaagtccgcatgtctcagactgacctg aaggtagttccaccatcggttccagatcgatcaccgaaggctttgtctgttcctgcagca acaggtgtagaggctattggtaatgagatttttgatgctgaatgtctcaaacttataaat gagtacttctatggagtgcgaatatttcctggtcaagacccaacacatgtgtatgttgga tgggtaacaactcagtaccatgtccatagaaaagacttcaaccagagccatgttcagaaa gcatctgtaacaatagtggatgagtatgaaagaataatggagagtgttgaccgtcaaagt tgctacatggtgcgagctgatgagctttacaatgaagtaacaaatgatgcatcaggaaaa ggggcatcacaagggatgtttattgggtgcttcgttgatgctgctactggttatgtgaca tttacctgtgaaggaaaggaaacaaaccatcgattcaagatggaaccagagacaaaactt ttcccagccatttttgtagaggcaacaagtaaagaaattctacagatagagttgggaaga acatcaacgacactcccattgtcagctgcagtactgcagaattcagagaggcatgtcata ccacagttcccaccaagactgaaagtgcagtgcttaaagccacaccagtgggcacgggtt ccaaaccagtctcttcaagttcatgctttgaaactatctgatatccgtggctggagtatc ctctgtgaagatcctgtgtcaatgcttgctttacacatacctgaagaggatagatgtatt gatattctggagcttattgaaatggaaagattactcagtttccatgctcacaccttaact ttgtacgctgcattgtgctaccagtcaaactaccgtgcagctcacgccctgtgccaacat gtggatcagaaacagttgctgtatgctattcgctcagagtacatgtctggtccactacga cagggattttatgacttacttatagcccttcacctggaatcacatgcaacaacaatggag gcatgtaagaatgagtacataattccacttggtcaagaactgaaagaattatatgagaat cctgatatgagacacagccttaggtctctaaaaacagaatcagttagacctcagatgaaa atgactgatatagctgaaacaattgaaaacatcaggaacttgtatagtccagatttccca cttgatgctgttaaggattatatcatggctgcgttggatgaagctgttcaagtaaaccaa gtacataacagggatccaattggaggtagcaatgaaaatttgttcttgccattactgaaa ctagtggatcgcctgctactagttggattgctcactgatgaggatgtggggaaactacta attatgattgatccagaaacttgggacagttcatttgacaaagaggggaaggatgagcat aggaaaggactgcttcaaatgaaaatggcagaaggagccaagctacagatgtgctatctt ttgcatcacttatgcgacagccaattacgtcacagagttgaatcaatcattgccttcagc catgattttgttgcagaactacaaacagaccagctgaggagatatgttgacatcaaacag tcagacctcccatcagcagttgcagctaaaaagacaagagaatttaggtgccctccaaaa gagcagatgaatgcaattcttggttttaaaaaccttgaagaagaggacaaggaaaactgc ccatgtggagaagaactaagagatcaactgaatgcattccatgaaaaattaatgtcacat gtttcacttaacgcactacgagatgcagaagaagctgaggaaaatgcagttgaagtagtg aaacctggtcctattaagcgcctgtacaacttcatcaatgcggtgaaagagatggaggaa gaacctaaggaagcagtagaacctgaaaagaaaacacctgaagagatattccgcaaggta cttatcaaaacaattgtcagatgggcagaggagtctcagattgaaacaccaaaactggtc cgagaaatgtttggcttattggtaagacagtatgacagtattggagaacttattcgggct ctacaaaaaacatacgtaatcaacagcaaaacaaagaatgatgtagctgccatgtgggtg ggactgagtcagattagagcattgttgcctgtacagatgtcacaagaagaggaggaatta atgagagagcgcttatggaaacttgtgaacaaccacacgtttttccagcatccagatttg attagaatcttgcgtgttcatgaaaatgtgatggctgttatgatgaacacattgggccgt agggcccaagcgcagtcagacactcagacacaggctcaagcaactggccaagagggcgag gtttctgcaaaagagaaggatacttcccatgagatggtggtagcttgctgcagattcctt tgctatttctgtagaacatcccgacaaaaccagaaagcaatgtttgatcatttctcattt cttctggaaaacagtaacattctgctgtctaggccttcactaagaggaagtacccctctt gatgtagcctattcatctctcatggagaacactgagctggccttggcacttagggaacat tatttagaaaaaattgctatctatctttctcgctgtggtctgcagtccaactcagaactt gtggagaaaggatatccagatttgggctgggatcctgtggaaggagagcgttatttggat ttcctcagattctgtgtctgggtcaatggtgagagtgttgaagaaaatgctaatttagta attcgccttctgatcagaagaccagaatgcttaggtcctgctcttagaggagaaggagaa ggccttctaagagcaataattgatgcaaataagatgtcagagcgcattgctgatagaaga aaagtaatggatgaggcagaaggaactatgacagtgatgcagtttgagcatcctttacca gaaagtgaagatgatgaagattatatagatactggtgctgcaattcttaatttctattgc acactggtagatctgcttggacgatgtgctccagattcatctgtgattctgcagggaaag aatgagtccctcagagctcgggcaattttaaggtctttagttcctcttgaggatcttcag ggtgttctgagtttaaagtttacactgcaaaatcctgcagctggagaagaaaggccaaag agtgacatgccatctggccttataccagcaaataaacagagcattgttttgttcctggag agagtttatggcattgagacacaagaacttttcttcaggctactggaggaagcttttctt cctgatctcagagcagcaactatgctggataggaatgatggatatgaatcagacatggcc ttagcaatgaatcgttacataggaaattctattttgccacttctcatcaaacattctaaa ttttataatgaggctgataactatgcaaaccttctggatgcaacattgcatactgtgtat cgtctttccaagaataggatgctcaccaaaggccaaagggaagctgtgtctgacttcttg gtcgctcttaccagccaaatgcagccaagcatgctcttgaaactactgagaaagttgaca gttgatgtctcaagattgtctgaatacaccacagtagcattaaggcttctgatgttacat tatgagcgctgtgccaagtactatggcacatcttttggacagggcatgtatggagcatca agtgatgaagaaaaacggttgaccatgatgctatttagcaatatttttgactcattgtct aaaatggattatgatccagaactgtttggtaaagcactgccttgcctcacagcaatagga tgtgcccttccacctgattactcattgtcaaagaattatgatgatgaatggtatggatca aaagatacgtcagatcctgatgggccatacaacccacagcccataaacacaagcagtgtt gtgttgaacaatgacttgaacacaattgttcagaagttctcagaacattaccacgatgcc tgggctagcaggaaattggaaaatggatgggcatatggtgagcagtggtcagattcatct aagacacaccctcgtcttaaaccctacaacatgttgaacgactatgaaaaggagcgctac aaagaacctgtacgagaatcattgaaagctctcttggctattggctggactgtagaacat acagaagtggaaattccatcaaacagcagaaattccatgagaagatcatcaaagggagga gaacagtcttccacaccttttaactataaccctcatcctgtggatatgaccaatcttaca ctgagcagagagatgcagaacatggctgaaaggcttgctgagaatgctcatgacatttgg gccaaaaagaagaaggaagaactcattacttgtggtggtggcattcatccacagttagta ccttatgatctgctgacagataaggaaaagcgaaaggacagggaacgatcacaggaattc ttgaagtatctgcaataccagggctataaactacacaggccaacacggtctggtgctgga gaatcagaacaaacgactggtgccatatcagtagagctgagatttgcatacagtctgttg gaaaaattaatacagtacctagacactgcatcaattaatatgaaaatgttcaaaccatca agcaccttcagccgacgaacaagcttcaaaacttcaacaagagacatcaaattcttttcg aaggttgtgcttcctctaatggaaaagtatttcagcacccacagaaattacttcatcgct gtagcaacagccactaacaatgtaggggcagcatcacttaaagaaaaggaaatggtagca agcttattctgcaaacttgctagtttgctaagatctcgcctggctgcctttggagctgat gttagaatatcagtcagatgtctgcaagtcctagtcaagagcattgatgcaaagtctctc gtgaagaactgtccagaattcatccgaacgtcaatgcttacatttttcaataatgttgct gatgatcttggacacacaatacaaaacctgcaggaaggccgttatagtcacctgcgaggg actcacctgaagacatcaacttcattgtcctacattaatggagtcgttctccctgttctt actgcaatgtttgatcatcttgcagcctgtgaatatggaagcgatctcttattggatgaa attcaggttgcatcatacagaatgttaagcagtctctacactctcggaattgatgcaact ctgactcatgataggaagtacctgaagactgaacttgagaggcaccgcccagcacttggt agctgccttggtgccttctcttctacattcccagtagcattccttgagcctcatctaaac aagcataatcagttctcactattaaatcgcatagctgaccattctttggaagcccaagat gtaatggcccgaatggaacaaagcatgcctactctagaaactgtactcagtgatgtggat cagtttgttgagtctgacaagtcacatgcagatgctccacacataattgacgtcattttg cctcttctttgttcatatttgcctttttggtgggcacagggaccggacaatgttagtcca actgggggagctcatgtgtcgatggtgactagtgaacatatgaaccagctgttgaaaaat gttctgaaattgataaaaaagaatataggcaatgaaagtgcaccttggatgataaggata gcagcatatacacagcagataataatcaactcttcagaagaactgcttaaagatccattc cttccacttgctgagaaagtgaagaaacgaacagatactctgttccacaaggaggagtca ctcagaggtttcattaaatcagcaactgatgatacttcacagattgagtctcaaattcaa gaagactggcatctacttgtgcgagacatatatgctttttaccctcttcttataaagtac gtggatctgcaaagaaatcattggcttagacacaatgtcgctgaagctgaagatttatat aaccatgtagccgaaatatttaacacatggtcaaaatctcagtatttcatgcgtgaagag cagaacttcatctcagcaaatgagatagacaacatggtactcatcatgcccacagccagc aggcggtctgcagtagtttctgatgtgtctcagctaggtggtggcagcaagaaaaagaag aagcaccgtgataagaagcgagacaaagacaaggaactgcaggctagtttaatggttgcc tgcctgaaacgcttgcttccagttggcttgaacctctttgctggaagggaacaagaatta gtgcagcactgcaaagacaggttcttaaagaagcttcctgaaagtgagatattggagttt gccaagatacagcttacacttccagataaaattgatccggctgatgagatgtcttggcag cattacctttattccaagctcggacagaaaaaaaatggagaagaaggaaaaccgacaaaa gtagaagacgttgtagagaggatagttgccatgtcaaaagtgctgtatggacttcatatg caagccaacaaaccaaaacccagtcgtgacggatggaaaagagtgttatctgcagctcgt aagagggcagccattgcatgtctgcacagtgaacctctgcataagcttaggaggcacaga gctatcaacatctatgtgcgttcctattgcgatctgtggctgcaggatgagaatgttggc caggagataatgattgaagatctgactcaatcctttgaggacgccgaactgaaaaagcgt gatgaacaggaagatgaaggaaaaccagatcctctaaatcaacttgtgacaaccttctgc cgaggagccatgactgaacgaactggagctctacaagaagatccactgtacatgtcgtat gctgaaatccagtccaagtcttgtggagaggaagaagaagaaggtgaagaagaaggcggt gatgaagagggagcagcttcaatccatcgaacaatggacaaattaatggaacaagaaatg gaaaaacaaaagctcctgttccaccaagcacgcttagcaaatcgtggtgttgcagagatg gttcttctgcatatatcagcatgcaaaggagtaccaagtgaaatggttatgaaaactttg caactcggtatatcaatactgagaggaggaaacagtgatattcaaatgggaatgctaaac cacctcaaggaaaagaaggatgttggtttcttcacgtcaattgccggtcttatgaactcc tgcagtgttctggacttagatgcatttgaacgcaacactaaagctgaagggcttggggta ggatctgaaggagctgcaggagagaagaacatgcatgatgctgagttcacttgtgccctc ttccgattcatacaactgacctgtgaagggcacaatcttgaatggcagaattacttgagg acacaggctgggaatacaacaacagtgaatgttgtcatctgcactgttgactacctgctg cgattacaggaatcaataatggatttctactggcactactcaagtaaggaaataatagat cctgctggtaaggcaaatttcttcaaagccattggggtagcaagtcaggtgtttaacaca cttactgaagtaatccaggggccgtgcacacagaaccagcaggctctggcccattcaagg ctctgggatgcagttggaggcttcctgttcctgttttcacacatgcaggacaaactttca aaacattctagtcaggtagacctcctgaaggaactattgaatttgcagaaggacatgata acaatgatgctgtccatgcttgaaggcaatgttgtgaatggtacaattggcaaacagatg gttgacacactagtagagtctgcatctaatgtggagttgatcctgaaatactttgacatg ttcttgaaattaaaggaccttacaagttctgcaagtttccaggaaattgatatcaatcat gatggatgggttactccaagggaattcagggagaaaatggaacagcagaagagctacacc attgaggagattaacttcttgttaatgtgctgtgatacaaatcatgatgggaaaatagac tacgttgaattcactgaaagatttcacaaccctgcaaaagaaatcggctttaacctggca gtgctcctaaccaacttgtcagagcatatgcccaatgagccaaggttggcacgtttcctg gaaacagctggaagtgtattgaattactttgaaccatatcttggacgcatagagatattg ggtggcagcaagagaattgaaagagtttactttgaaataaaggagtcaaatattgaacag tgggagaaaccacaaattaaggagtcaaagagggcattcttttactcaattgtcactgaa ggtggtgacaaagaaaagcttgaagcctttgtgaacttctgtgaagatgccatctttgaa atgactcatgcaagtggtttaatggcaagtgaggaaagctctacaattggaaaggcaaga gaagcatcatacagttacatgacagaagaagacgaagagcgggctgcaaaagatccaatt cgcagaggcatccaagctgtaaaagatgcagtttatttctcgttggctttgttgtcacct accaacatcaagaacaaaattaatgagcttcaacagatgtcatttatggaattatttgtt ggattctttaagctcattttctatgttttctactattcaggatttggagtctctgtggtg atcaagtatgttgttggaatcttaatgtcactcatgagaggaccgcaaatagaagagcct gttgtcgaggtgaaagaagaagaacggatgggtcctttacgtgtgttaccagcattacct gcgacaccagatgaagcaaatgccccacagcagatgcaggcatttggtttggatattaca aaagaggataatgggcagtatcacatggttccacatgaaagtgctccaccatctccacag tcaagcgttgaagaaggcggagacacaactcctgaggagggggcagaagaacatgccaag caagaagctgctgaaggggaatcacctatgagccttgtggacttacttggtggtgatgca gcacgcaaagctgcagctgcaactgctgaggcagcagtacagcagcaggctgcaatggca gctgttgaagcggaatccaagcaggaggttgtggttgaaccatcagcaatgtcccagatt gacttcagcgagtacacaaagagggctgtaagtttccttgcacgcaacttctacaacttg aaatatgttgcgttagtgcttgccttctgcatcaacttcatgctgttattttataaagtc acaactcttggtggtgatgatgacgaaaatggcaatggctcaggagaggaagtggctgat ttaatggaagaactctcaatggaagtgaattctacagaagtgggaagtgcagaaaatgga agtggcgaagaagaagaacccttagagctagtccatgtagatgaagactttttctacatg gaacacgtgttacgattaatggcattactgcattccatggtctcattagcaatgctcatt gcatattaccacttgaaggtaccactggccatattcaaaagagagaaagaaattgccagg agattggaatttgatggcttgtacatagttgagcagccagaggatgatgatataaaatcc cattgggacaagctggtgatatctgcaaagtcgttcccagttaactactgggataaattt gtgaagaaaaaggtccgtcaaaagtacagtgagacatatgattttgattccatcagtaat ttactaggaatggagaagacatctttcagtgcacaggaagaggaaggaggatctggctta atcaacttcattgcaaatattgattggaggtaccagatttggaaatcaggtgtaacaata acagataattcattcctgtacagcttgtggtacttcacattttcaatactgggcaacttc aaccgtttcttctttgcggcacatctgttagatgttgctgtgggtttcaagacgctacgt acgatattgcagtcagtaacacacaatggaaaacagcttgtactgacggtgatgttgctg acaatcgttgtgtacatttatactgttattgcctttaatttcttcagaaagttttatgta caagaggaggatgaagaagttgataagaaatgccacgacatgttaacgtgtttcgtgttc cacctgtacaagggagtgcgggctggaggaggcatcggtgatgaaatcgagccaccagat ggtgacgactatgaagtatatcgcatcatgtttgacatcacattcttcttttttgtcatt gttatcctgctggctatcattcagggtttgatcattgatgcttttggtgagctgagagat cagttggaaagtgtaaaagaagacatggagtcaaactgctttatttgtggtataggaaaa gattactttgataaagtaccacatgggtttgacactcatgtacaacaagaacataactta gcaaattatatgttctttttgatgcacttaatcaacaaaccagacacagaatatactggt caggagacctatgtctggaacatgtaccagcagagatgctgggacttcttccctgttggt gactgcttcaggaagcagtatgaagaggaactgggaggaggcggcggctag

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