Streptomyces graminofaciens: SGFS_005530 Help Entry SGFS_005530       CDS       T09325                                  Name (GenBank) Polyketide synthase   KO K16384   polyene macrolide polyketide synthase Organism sgrf  Streptomyces graminofaciens Pathway sgrf01052   Type I polyketide structures Brite KEGG Orthology (KO) [BR:sgrf00001]  09100 Metabolism   09109 Metabolism of terpenoids and polyketides    01052 Type I polyketide structures     SGFS_005530  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:sgrf01008]     SGFS_005530 Polyketide biosynthesis proteins [BR:sgrf01008]  Polyketide synthase (PKS)   Modular type I PKS    cis-AT PKS     Polyene macrolide PKS      SGFS_005530 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ketoacyl-synt Acyl_transf_1 KR Ketoacyl-synt_C PKS_DH_N PS-DH PP-binding KAsynt_C_assoc adh_short Thiolase_N ADH_zinc_N_2 Epimerase ADH_zinc_N Docking GDP_Man_Dehyd Polysacc_synt_2 ACP_syn_III 2-Hacid_dh_C ADH_N NmrA DUF6213 Motif Other DBs NCBI-ProteinID:  BBC29262 LinkDB All DBs Position complement(592445..609430) Genome browser AA seq 5661 aa AA seqDB search MGNEDKLRDYLKRVTADLQETRRRLAEAESGTPEPIAIVGMACRFPGGITTPEDLWRHLT SGAGVLSDFPADRGWDADALYDPDPAAPGKSYVRTGGFLHDAAYFDAEFFGIAPRMAVAM DPQHRLVLETAWEALERAGVTAESRGSDTGVFLGASYQDYLSRVAEAPADLEGYLMTGST ASVASGRVSYALGLEGPAVTVDTACSSSLVALHLASQSLRQGECSMALAGGVVVMSTPNV FIEFSRQRGLAPDGLCKAFADGADGTAFSEGVGVLVVERLSDALRSGHRVLAVVRGSAVN QDGASNGLTAPNGPAQQRVIRQALAAARLRPADVDVVEAHGTGTRLGDPIEAEALIETYG QDRERPLLLGSVKSNLGHTQAVAGVAGVMKMVLSLEHGVVPPTLHVAEPTAEVDWSAGAV EVMREEHAWARGERPRRAGVSSFGISGTNAHVILEEAPAPAATPSSAGGPVVAGGVADPG VVPWVISAQSETALRGQAGRLAAHPVENAADTGYSLAASRSVFGHRAVVLGTDRETLLAG ARDLAEGRDNPSVIRGTSGTGNSTAGTSGAVLEEPTAFVFAGQGTQRVGMGRELAETYPV FADALREVCAAFEGLLPGPLLPVIFDEPELLDRTEWTQPALFAVEVALARLLEHWGIRPD AVVGHSIGEIAAAHVAGLWSLTDACRVVAARGLLMSELPEGGAMLSVAAPEHEIAPLLPD RAEIAAVNGPTSVVVSGDATAVTETADLCARQGWKTKRLRVGHAFHSAHMDPILEPFRQV LESVKYHEPHTPLTSTATGERVSPADLRSPDHWTRQVRDRVRFQEAIRRLAADGVTRFVG IGPDTTAMAMTQDCLPDPTDAAAGATGDARKAPLAVSLMRPGHPEPTAALTALAELFVRG TTMNWAALFSASGARRVDLPTYSFQRERYWLEASHPRDVTRAGLLGAEHPLLGAVVTDPE SGGVTLTGRLSLAEQPWLADHAIAGTTILPAAAFVELVVRAGDEVECGEVEELTLHAPLV LPSSGGAQVQVRVGASDESGRRLVGVYARAESAAADGWTRHASGTLAATASAPEDVEALT QWPPRDAVSLPSVSEVYDDFTGRGYAYGPVFQGLRAAWRRGDEVFAEVALPEGAASEAAE YGLHPALLDAALQSMTFLPDDAFRTATPALPFTLSGVTLRTAGASALRVRVRRTGEDTVT VQVYDPTGAPVASIDALVTRPVPVEQLAAGQGMRDCLFTVEWSPVSADGGVPEKQWTVLA DPASGEDTETDVAFVRCPAGPDARTVTATALAWIQAWLDDPVRESARLVFVTRGAVATDS DDAPTCLEQAGVWGLVRSAAREHPGRFALVDLDTDLPADDETWTTLAARVASESELALRD GRALVPRLTRAVAVSEGRGLGDLAGRTVLITGGTGGLGSLVARHVVAAGAGHVLLAGRRG PDAPGVAELTLELAQLGARVSVVACDVGERDAVAELLASVPAEFPLTAVIHTAGVVDDGV VTSLTSGQLDAVFGAKADAAWHLHELTRDMDLSAFVLFSSLSGVMGAAGQANYAAANATL DALAAHRRAQGLPAVSLAWGLWERTSGMTGHLAQTDFARMTRAGVRPLSSEQGLALLDAA VGMAEALVVPARLDAAAARAADGEVPPVLRGLAGGGVRRPLSRATATAAGAAPGDQGLAT RLTSLSEADQYELLLDLVRTHLAAVLGHTRSTTLDAGRAFKDLGVDSLTAVELRNRLNTA TGLRLPATLVFDHPSAGSLAAFLRTELLGVRSTAAHDIADADADTGADSDPVVIVGMACR FPGGVSSPDEFWELLAAGGDAISGLPTDRGWDVEGLYDPDPDQLGKTYSVEGGFIDDATR FDADFFGISPREALAMDPQQRLLLETSWEALERAGIDPDSLRESRTGVFAGLSDSGYGAR LWDDEAAVGGYRATGSAASVASGRVAYALGLQGPAMSVDTACSSSLVALHLATQSLRQGE CSMALVGGVMVMSTPAVFVEFSRLRGLAADGRCKPFAASADGTGWAEGVGVLVVERLSDA RRRGHRVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALAAAGLRPGDVDVVEAHGTG TRLGDPIEAEALIAAYGEGRERPLLLGSVKSNVGHAQAAAGVAGVIKMVLSLRQGVVPAT LHVDEPTWEVDWSAGAVELVRERRSWPEVERPRRAGVSSFGISGTNAHVILEEAPLVEEP VGVGESVLGVVPWVVSARSEAALRGQARRLAGLSDGRPVDVGYSLAVSRSVFGERAVVLG ADREELLAGVRALAEGREASHVVRGQGAGVRRAVFVFPGQGSQWVGMAAGLLEESETFRD QIVACDEVLAPLTGWSLLDVLRGVDGSPGLERVDVVQPVLWAVMVGLGRLWRSLGVEPAA VVGHSQGEIAAAVVAGVLSLEDGARVVAERSRLLNVLSGRGGMVSVPLPVDAVRLLLVPW SGAVGVAAVNGPRSVTVSGDVAALEELLARCEADGIDARRVAVDYASHSAHVEDIQAELL DALAPVVMRKAEVPFYSTVTAGLLETGGLDAGYWYRNLRQTVELEETVRGLAEDGFDAFI EVSPHPVLVPPVQDTLDEALEDTGVVLGTLRRDEGGLGRFTTSLAQAHVQGIGVDWAEFF TNTGAQQVDLPTYSFQHKRYWLDISTSRDISGVGLSGTDHPLLGAVVTDPESGGVTLTGR LSLAEQPWLADHAIAGTTILPAAAFVELVVRAGDEVVECGEVEELTLHAPLVLPSSGGAQ VQVRVGASDESGRRLVGVYARAESADVDGQPAHGWTRHASGTLAATASAPEDVEALTQWP PRDAVSLPSVSEVYDDFTGRGYAYGPVFQGLRAAWRRGDEVFAEVALPEGAASEAAEYGL HPALLDAALQAATFLSEQSEETDREPESAKMPFALSGVTLRAAGASVLRVRLRRTGEDTL TVHASDPTGAPVASIDSLAMRPVSDETLAVADHAVRDRLFTVEWSALLPDQTAQPQSWTL ANPTEAVPAATDVVFALCPAGPDARSVTATVLAWIQDWLDDPTRESARLALVTQGAVPTG ADDAPTRMEQAGVWGLVRSAAREHPGRFALVDLDADLPSDDETWTTLAAHLGTEPEMALR EGRLLTPRLARAAAVPEARGLGDLAGRTVLITGGTGGLGSLVARHVAATGAGHVLLAGRR GPDAPGAAELVVELEQLGAQAAAVACDLSDREAVADLLNRIPADLPLAAVIHTAGAVDGG VVTSLTSGQLDAVFGAKADAAWHLHELTRDMDLSAFVLFSSLSGVTGAAGQANYAAANTA LDALAAHRRAQGLPAVSLAWGLWEQSSGMIRHLGEAGLSRTSRVGALPLSSEQGLALLDA AVGMGEALVVPARLDLASMRAADDIPLVLRGLAGGGVRRPLSRATAAGAGAAQGDQGLAT RLTGLSEADQYELLLDLVRTHLAAVLGHTRSTTLDAGRAFKDLGVDSLTAVELRNRLNTA TGLRLPATLVFDHPSLSALTAYLRTELAGSESTVETQYNGVAARPMNDDDPIAIVGMACR FPGGASSPEEFWELLLADGDAISGLPTDRGWDVAGLYDPDPDRAGTTYSAQGGFIEDIAG FDAGFFGISPREALAMDPQQRLLLETSWEALERAGIDPASLRESGTGVFAGVGDGGYGVR VWDEGAEVGGYRATGSAASVVSGRVAYALGLQGPAVSIDTACSSSLVALHLAVQALRGGD CSLALAGGVMVMSTSAGFVEFSRLRGLAADGRCKAFGAGADGFGLAEGVGVLVVERLSDA RRRGHRVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALAGAGLQPGDVDVVEAHGTG TRLGDPIEAEALIAAYGEGRERPLLLGSVKSNVGHAQAAAGVAGVIKMVLSLRQGVVPAT LHVDEPTWEVDWSAGAVELVRERRSWPEVERPRRAGVSSFGISGTNAHVILEEAPLVEEP VVVGDSVLGVVPWVVSARSEAALRGQAQRLVAHEEAAVVDVGYSLATSRSLLDHRAVVLG SDRESLLAGVRALAEGRETAGVVRGHSGGVRRAVFVFPGQGSQWVGMAAGLLEESETFRD QIVACDEVLAPLTGWSLVDVLRGVDGSPGLERVDVVQPVLWAVMVGLGRLWRSLGVEPAA VVGHSQGEIAAAVVAGVLSLEDGARVVAERSRLLNVLSGRGGMVSVPLPVDAVRLLLVPW SGAVGVAAVNGPRSVTVSGDVAALEELLARCEADGIDARRVAVDYASHSAHVEDIQAELL DALAPVVMRKAEVPFYSTVTAGLLETGGLDAGYWYRNLRQTVELEETVRGLAEDGFDAFI EVSPHPVLVPPVQDTLEEALDDRGVVLGTLRRDEGGLGRFTTSLAQAHVQGIGVDWAEFF TNTGALRVDLPTYSFQHDRYWLDLPTSRDVSGAGLSSPNHPLLGAVVTDPESGGVTLTGR LSLTDQPWLADHTIAGTTILPGTAFVELVVRAGDEVDCGEVEELALHTPLVLSSAGGTQV QVQVGGPDEDGRRTVAVHARPESAAADGGPAHGWTRHASGTLTPTPTAPDTTHPLTPWPP ENAIPVPVTDMYEDFAARGYAYGPAFQGIQAAWRRGDEVFAEVALPEHTVPEAAEYGLHP ALLDAALQATGFLPETGPDADPDTAFDTPKLPFAWTGVTLRALGATRLHVHLRRAAEGGV VIRTTDPDGTPVASADAVTMRPVPDSVLSSGFTPATAHDLFTVEWSTPPTVTSPSFPSWA LAENLTATPTTTPMTTPTTTDVVFALCPSGPDTRSVTTQVLDWIQAWTTAADRDATRLVL VTRGAVAEGPGDPVPSLEQAGVWGLVRSAAVEHPGRFALVDLDPDATAPDDETWTTLAGH LTTEPELALRDNRVLAPRLTRSAAPQIPPGSELRLTSDGSGSVAGLRCAPQAQPVRPLRP GEVRVAVRAAGLNFRDVLVALGVAGLGEAGMGGEGAGVVLEIGEDVPDLAPGDRVMGILG QAFGSTTVADHRLLVRVPSGWSFAEAASVPVVFATAYYGLVDLAGVKPGERVLVHAAAGG VGMAAVQLARHLGAEVFGTASPQKWEALTTLGLSAGHIASSRTLEFEPEFMTTTDNEGVD LVLNSLAGEFTDASLRLLSPGGRFLEMGKTDIRTPEQITVLRPEVTYRAFDLMDAGYERI GEILREVMALFERGVLRLPPIRAWDIRHAAEAFRFMSQARHIGKNVLTIPVPPSPQGTTL ITGGTGEIGGLVARRMAAAGAEHVLLTSRRGMEAPGAVELVAELEALGARVTVSACDMGD RQQAAVLLEGIPADRPLTAVIHAAGVVDDGVLGSLTPEHVDSVFRPKVDAAWHLHELTRE MDLSAFVLFSSLAGVTGAAGQANYAAANTALDALAAHRHAQGLPAISLAWGFWEQASGMT GHLGGSDLARMARGGVLPLSSEQGLNLLDTALALPIPLAAPARLDLSAIRASDDVPPILR ALALSGTGRPQASRTPAVAKPTGDDTLAARLTALPDADRHGLLLDIVRTHLSVVLGHTDP ATLDVDRAFKELGIDSLTAIELRNRLNTATGLRLPPTLVFDQPTATALARHLQQLLLPKA TPDTVHTDLDRLENLLAELATDGGGTGAMEQIARRLRQMAAGLSGEGEPAPAEDLETANA EEMLALIRNEFGMPGNAEGIG NT seq 16986 nt NT seq  +upstreamnt  +downstreamnt atgggcaacgaggacaagctccgcgactatctgaagcgggtcacggccgacctccaggag acgcgccggcgactcgccgaggcggagagcggcactcccgaaccgatcgcgatcgtcggc atggcgtgccgcttccccggcggcatcaccacccccgaggacctgtggcggcacctcacc tccggcgccggagtgctctccgacttccccgccgaccgcggctgggacgccgacgccctg tacgacccggaccccgccgcgcccggcaagtcgtacgtccgcaccggcggcttcctccac gacgccgcctacttcgacgccgagttcttcgggatcgccccgcgcatggccgtcgccatg gacccccagcaccggctggtcctggagaccgcgtgggaggcactcgaacgggcgggcgtc accgccgagtcgcgcggcagcgacaccggagtgttcctcggcgcctcctaccaggactac ctctcccgcgtcgccgaagccccggcggacctggagggctacctgatgaccggcagcacg gcgagcgtggcctccgggcgcgtctcgtacgcgctcggcctggagggccccgccgtcacc gtcgacaccgcctgctcctcctccctggtagccctgcacctcgccagccagtccctgcgc cagggagagtgctcgatggcactcgcgggcggggtcgtcgtcatgtcgacgccgaacgtg ttcatcgagttcagccgccagcgcggtctggcccccgacggcctgtgcaaggcgttcgcg gacggggcggacggcaccgcgttctccgagggcgtcggggtcctggtggtggagcgtctg tcggatgcgctgcgtagcgggcatcgggtgctggcggtggtgcggggcagtgcggtgaac caggacggtgcgtcgaacgggctgacggcgcccaacggcccggcgcagcagcgcgtgatc cggcaggccctggccgccgcccgcctccgccccgccgacgtcgacgtcgtggaggcgcac gggacggggacgaggctcggtgacccgatcgaggcggaggccctgatcgagacgtacggc caggaccgcgaacggccgctgctgctcggctcggtgaagtcgaacctcgggcacacccag gccgtcgcgggcgtcgccggcgtgatgaagatggtgctctccctggagcacggcgtcgtc ccgccgaccctgcacgtggccgagccgacggccgaggtcgactggtctgcgggcgccgtg gaggtgatgcgggaggagcacgcgtgggcgcgcggcgaacggccgaggcgggcgggcgtg tcgtcgttcggtatcagcggcacgaacgcgcatgtgatcctcgaagaggcgccggcgccg gcggcgacgccgtcgtcggccgggggccccgtcgtggccggtggcgtcgcggatcccggt gtggtgccgtgggtgatctcggcgcagagcgagaccgcgctgcggggccaggccggacga ctggccgcccatccggtggagaacgcggccgacaccggctactccctggcggcctcccgc tcggtcttcggccaccgggcggtggtcctcggcacggaccgggagacgctgctggccggg gcgcgcgacctggccgagggccgggacaacccctcggtgatccgtggcacgtccggcaca gggaactcaacggcgggtacctcgggcgcggtgctcgaggaaccgaccgcgttcgtcttc gccggccagggcacccagcgcgtcggcatgggccgcgaactggccgagacataccccgtg ttcgcggacgcgctgcgggaggtgtgcgcggccttcgagggcctgctgcccggcccgctg ttgccggtgatcttcgacgagccggagctgctcgaccggaccgagtggacccagcccgcg ctcttcgccgtggaggtcgcgctcgcacggctgctggagcactgggggatccgccccgac gcggtggtcggccactccatcggggagatcgccgccgcccatgtcgcgggcctgtggtcg ctgaccgacgcctgccgggtggtcgcggcccgcggcctgctcatgagcgaactgccggag ggcggcgcgatgctctcggtggccgcccccgaacacgagatcgcacccctgctcccggac cgcgccgagatcgcggcggtcaacggccccacgtccgtggtcgtctccggcgacgcgacg gccgtgaccgagacggcggacctgtgcgcgcggcagggctggaagaccaagagactccgg gtcggccacgccttccactccgcgcacatggacccgatcctcgaaccgttccgccaggtc ctggaaagcgtcaagtaccacgaaccgcacaccccgctcacctccaccgccaccggcgaa cgcgtctccccggccgacctccgctcacccgaccactggacccgccaggtacgcgaccgg gtccgcttccaggaggcgatccgccgacttgccgccgacggcgtgacacgtttcgtcggc atcggccccgacaccacggccatggcgatgacccaggactgcctgccggacccgaccgac gcggcggcgggcgcgacgggcgacgccaggaaggccccactggcggtgtccctcatgcgg cccggccaccccgaaccaaccgccgcgctgaccgcgctcgccgaactgttcgtccggggc acgacgatgaactgggcggcgctgttctcggcttcgggcgcacgacgcgtggacctgccg acctacagcttccagcgcgagcgctactggctggaggcgtcccacccccgggacgtgacc cgcgcgggactcctcggggcggaacatccgctgctcggggcggtggtcacggatccggag tcgggcggggtgacgctgacgggtcgcctgtccctggccgagcagccgtggctggcggat cacgcgatcgccggtacgacgatcctgcctgccgccgcgttcgtggagctggtggtgagg gcgggcgatgaggtggagtgcggtgaggtcgaggagctgaccttgcatgcgccgttggtg ttgccgtcttcgggcggggcgcaggttcaggtgcgggtcggtgcgtccgatgagtccggt cggcggctggtaggcgtgtacgcccgtgccgagtcggctgctgctgacggctggacccgt cacgcaagcggcacgttggccgcgactgcctccgctcccgaggacgtggaggcgctcact cagtggccaccgcgagacgcggtctcgttgccgtcggtctccgaggtgtacgacgacttc accggccggggctacgcgtacggcccggtgttccagggcctgcgagcggcgtggcgacgc ggcgacgaggtcttcgccgaagtggccctgcccgagggcgccgcatcggaggcggccgag tacggcctgcatccggccctgctggacgcggcactccagtccatgacgttcctccccgac gacgcgttccgcacggcgaccccggccctgcccttcaccctcagcggagtgaccctgcgg acggcgggcgcctccgcgctccgcgtacgggtgcgccggacgggcgaggacacggtgacc gtccaggtgtacgaccccaccggcgccccggtggcctcgatcgacgccctggtgacacgc cccgtaccggtcgagcagctcgcggcagggcaagggatgagggactgcctgttcaccgtg gagtggtcgccggtatcggccgacggcggcgtgccggagaaacagtggaccgtgctcgcg gacccggcctccggcgaggacaccgaaacggacgtggccttcgtccggtgtccggcgggg ccggacgcacgaacggtgacggcgacggcgctggcgtggattcaggcgtggctggacgac ccggtgcgggaatcggcgcgcctggtgttcgtcacgcgtggtgcggtggcgacagacagc gacgatgctccgacttgcttggaacaggcgggtgtgtggggtctggtgcgctccgccgcg cgcgaacatccgggccgtttcgcgctggtcgacctggacaccgatcttcccgccgatgac gagacgtggacgacgctggcggctcgcgtcgcctctgagtcggagttggcgcttcgcgac ggccgggcgctggttccgcgcctgacgcgtgccgtcgccgtttccgaggggcggggcctg ggggatctggccgggcgtacggtcctgatcaccggtgggacgggcggcctgggctccttg gtggcccggcatgtggtggcggcgggcgcggggcacgtactgcttgccggccgacggggt ccggacgcgccgggcgtcgccgaactcaccctggaactcgctcagttgggtgcccgggtg agcgtcgtggcctgcgatgtgggtgagcgggacgccgtggcggagttgctggcgagcgtc ccggcagagtttccgctgacggccgtgatccacacggcgggtgtggtggacgacggagtg gtgacgtccctgacttccggtcaactggacgcggtgttcggggcgaaggcggacgcggcc tggcatctgcatgagctgaccagggacatggacctgtcggccttcgtcctcttctcctcc ctctccggtgtgatgggagcggcggggcaggcgaactacgcggccgctaacgcgacgctg gacgctctcgccgcccaccgccgcgcccagggactcccggccgtctccttggcctggggc ctgtgggagcggaccagcggcatgaccggccacctcgcacagacggacttcgcccggatg acgcgggcgggcgtacggccgctgtcgtcggaacagggtctggcgttgctggacgccgct gtggggatggctgaggccttggtcgtacccgcacgcctggacgcggcggcggcacgagcc gccgacggcgaggtgccgccggttctgcggggcctggcgggtggtggcgtcaggcgtccg ctgtcccgcgcaaccgccaccgccgcgggtgcggctccgggcgatcaggggctggccacc cggctgaccagcctctcggaagcggaccagtacgaactcctgctggacctcgtccgtacc cacctggcggcggtgctgggccacacccggagcaccaccctcgacgcgggccgcgccttc aaggacctgggagtcgactcactcaccgccgtcgaacttcgcaatcgcctgaacacggcc accgggctgcgtctgcccgccaccctcgtcttcgaccacccttccgccggttcgctggca gccttccttcggacggagctgctgggcgtacggagtaccgccgcccatgacatcgccgat gccgatgctgacaccggcgccgactcggacccggtcgtgatcgtggggatggcgtgccgt ttcccgggcggggtgtcttcgcccgacgagttctgggagctgttggcggcgggcggggac gcgatctccgggctgcccacggaccgtggctgggacgtggaagggctgtacgaccccgac ccggaccaactgggcaagacgtactcggtcgagggcggtttcatcgacgacgccacgcgc ttcgacgccgacttcttcgggatctcgcctcgcgaggcgctggcgatggacccgcagcag cgtctgctgctggagacgtcgtgggaggcgttggagcgggccggcatcgaccccgactca ctgcgggagagccggacaggtgtgttcgcgggcctgagcgacagcggctacggagcccgc ctgtgggacgacgaggccgcggtcggcggctaccgcgccaccggcagcgccgcgagcgtg gcctcgggccgtgtcgcgtacgccctgggcctgcagggcccggccatgagcgtggacacg gcgtgctcgtcgtcgctggtcgccctccacctcgcgacccagtccctgcgccagggcgag tgctccatggccctggtgggcggcgtgatggtgatgtccactccggccgtcttcgtggag ttcagccgtctgcgggggctggcggcggacggccgctgcaagccgttcgccgcgtccgcc gatggcaccgggtgggccgagggtgtgggcgtgcttgtggtggagcgtctgtcggatgcg cggcgtcgtgggcatcgggtgttggcggtggtgcggggcagtgcggtgaaccaggacggt gcgtcgaatggtctgacggcgccgaacggtccggcgcagcagcgggtgatccggcaggcc ctggccgccgccggcctgcggcccggtgatgtggatgtggtggaggcgcacgggacggga acgcggctcggtgacccgatcgaggcggaggcgttgatcgcggcttacggggagggtcgg gagcggccgttgttgctggggtcggtgaagtcgaacgtcggtcatgcgcaggcggctgcg ggtgtggcgggtgtgatcaagatggtgctgtcgctgcggcagggtgtggttcccgcgacg cttcatgtggatgagccgacgtgggaggtggactggtcggcgggggccgtggagttggtg cgggagcggcggtcgtggccggaggtcgagcggccgaggcgggcgggggtgtcgtcgttc ggcatcagcggcacgaatgcgcatgtgatcttggaggaggcgccgctggtcgaggagccg gtgggtgtcggtgaatcggtactgggcgttgtgccgtgggtggtctcggctcggagcgag gccgcgttgcgagggcaggctcggcggttggcggggctttcggatgggcgtccggtggat gtggggtattcgctggcggtctcgcgttccgtgttcggtgaacgggctgtggttctgggt gctgaccgggaggagttgctggcgggggttcgtgctcttgcggaaggtcgggaggcttcc catgttgtgcggggccagggcgccggtgtcaggcgcgcggtgttcgtgtttccggggcag gggtcgcagtgggtggggatggctgcgggtctgctggaggagtccgagaccttccgggat cagatcgtcgcgtgcgatgaggtgctggcgccgttgacgggttggtcgctgctggatgtt ctgcgtggggtggatggctcgccggggcttgagcgggttgatgtggtgcagccggtgttg tgggctgtgatggtgggtctgggccggttgtggcggtcgttgggtgtcgagccggcagct gtggtggggcattctcagggtgagatcgcggcggctgtggtggctggggtgttgtcgctg gaggacggtgcccgggtggtggctgagcgcagccgtctgctgaatgtgttgtcgggtcgg ggcgggatggtgtcggtgccgctgccggtggatgcggtacggctgttgctggtgccgtgg tccggggctgtcggtgtcgctgcggtgaacgggcctcgttcggtgacggtgtccggtgat gtggcggcgctggaggagttgctggcccggtgtgaggccgatggcatcgacgcgcgcagg gttgcggtggactatgcctcgcactcggctcatgtcgaggacatccaggccgagttgctg gacgcgttggcgccggtggtgatgaggaaggcggaggttcctttctactcgacggtgacc gctggtctgctggagaccggtggtctggatgccgggtactggtaccgcaatctgcgtcag acggtggaactggaggagacggtacgggggctggcagaggacggcttcgacgcgttcatc gaggtcagccctcacccggtcctcgtccccccggtccaggacacactcgacgaggccctc gaagacacgggcgtcgtcctgggcaccctccgccgagacgaaggcggcctcggccggttc accacctccctcgcccaggcccacgtacagggcatcggcgtggattgggccgagttcttc acgaacacgggcgcacagcaggtggacctgccgacctacagcttccagcacaagcgctac tggctggacatctccaccagccgcgacatatccggtgtcggcctgtccggaactgatcac ccgttgctcggggcggtggtgacggatccggagtcgggcggggtgacgctgacgggtcgc ctgtccctggccgagcagccgtggctggcggatcacgcgatcgccggtacgacgatcctg cctgccgccgcgttcgtggagctggtggtgagggcgggcgatgaggtggtggagtgcggt gaggtcgaggagctgaccttgcatgcgccgttggtgttgccgtcttcgggcggggcgcag gttcaggtgcgggtgggtgcgtccgatgagtccggtcggcggctggtgggcgtgtacgcc cgtgccgagtcggccgacgtcgacgggcaaccggctcatggctggacccgtcacgcaagc ggcacgttggccgcgactgcctccgctccggaggacgtggaggcgctcactcagtggcca ccgcgagacgcggtctcgttgccgtcggtctccgaggtgtacgacgacttcaccggccgg ggctacgcgtacggcccggtgttccagggcctgcgagcggcgtggcgacgcggcgacgag gtcttcgccgaagtggccctgcccgagggcgccgcatcggaggcggccgagtacggcctg catccggccctgctggacgcggccctccaggcggccacgttcttgtccgagcagagtgag gagacggaccgggagcccgagtcggcgaagatgccgttcgccctgagcggggtgaccttg cgagccgcaggtgcttccgtgctccgcgtacggttgcgccggacgggtgaggacacgctg accgtccacgcgtccgaccccaccggcgccccggtggcctccatcgactccttggcgatg cgcccggtgtcggacgagaccctcgctgtcgcggaccacgcggtgcgggaccgcctgttc accgtggagtggtctgcgctgctgccggaccagactgcccagccgcagagctggacgctg gcgaacccgaccgaggccgtgcccgcggcgacggacgtggtcttcgcgctgtgcccggcg gggccggacgcacggtcggtgacggcgacggtgctcgcgtggattcaggattggctggac gatccgacgagggagtcggctcggctggctctcgtcacgcagggcgcagtgccgacaggc gcggacgacgccccaacccgtatggaacaggcaggcgtgtggggtctggtgcgctccgcc gcgcgagaacatccgggccgtttcgcgttggtcgacctggacgccgatcttccctccgat gacgagacgtggacgacgctggcggctcacctgggcaccgaaccggagatggcgctccgc gaaggtcgcctcctcaccccccgcttggcccgtgccgccgctgttcccgaggcgcggggg ctcggggatctggccgggcgtacggtcctgatcaccggcgggacgggcggcctgggctct ctcgtggcccggcatgtcgccgcgaccggcgcggggcacgtgctgctggccggtcgacgg gggccggacgcacctggggcagccgaactcgtcgtagaactggaacagttgggtgcacag gcggctgcggtcgcctgcgacctgagcgatcgagaagcggtggcggatctcctgaaccgc atcccggccgacctccccctcgcggctgtgatccacacggccggtgcggtggacggaggc gtcgtgacctctctgacttccggtcaactggacgcggtgttcggggcgaaggcggacgcg gcctggcatctgcacgagctgacccgggacatggacctgtcggccttcgtcctcttctcc tccctgtcgggtgtcacaggagcggccggtcaggcgaactacgccgccgcgaacaccgcc ctcgacgcgctcgccgcacaccgccgcgcccaaggcctccctgccgtctccctggcctgg ggcctgtgggaacagagcagcggcatgatccgacacctgggcgaggcgggtctctcccgt acctccagggtgggcgcgttgcccctgtcgtcggaacaaggcctggcgttgctggacgct gctgtggggatgggcgaggccttggtcgtaccggcacgcctggacctggcatccatgcgc gcagccgatgacataccgctggtgctgagggggctggcgggtggtggcgtcaggcgtccg ctgtcccgcgccaccgctgcgggtgcgggggcggctcagggcgatcaggggctggccacc cggctgaccggcctttcggaggcggaccagtacgagcttctgctggatctcgtccgtacc cacctggcggcggtgctgggccacacccggagcaccaccctcgacgcgggccgcgccttc aaggacctgggagtcgactcactcaccgccgtcgaacttcgcaatcgcctgaacacggcc accgggctgcgtctgcccgccaccctcgtcttcgaccaccccagcctctccgcgctgacc gcctacctgcggaccgaactggcgggcagcgagagcacggtggaaacgcagtacaacggc gtggcagccaggcccatgaacgacgacgatccgatcgcgatcgtgggcatggcgtgccgc ttcccgggcggggcgtcttcgcccgaggagttctgggagcttctgctcgccgacggggac gcgatctccggactgcccaccgaccgcggctgggacgtggcgggactgtacgaccccgat ccggaccgggccgggacgacgtactcggcccaaggcggcttcatcgaggacatagcggga ttcgatgccggctttttcgggatctcgcctcgcgaggcgctggcgatggatccgcagcag cgtctgctgctggagacgtcgtgggaggcgttggagcgggccggtatcgaccccgcctcg ctccgcgagagcgggacgggcgtcttcgccggcgtcggtgacggcggctatggcgtccgg gtctgggacgagggtgccgaggtcggcggttaccgcgccaccggcagcgccgcgagcgtc gtctcgggccgtgtcgcgtacgcccttggcctgcaaggccctgcggtcagcatcgacacg gcgtgctcgtcgtcgctggtcgccctgcacctcgccgtccaggccctgcgcggtggtgac tgctcgctcgcgttggccggcggtgtgatggtgatgtccacctcggccgggttcgtggag ttcagccgtctgcgggggctggcggcggacggccgctgcaaggcgttcggcgccggggcc gacggattcggcctggccgagggcgtcggagtcctggtggtggagcgtctgtcggatgcg cggcgtcgtgggcatcgggtgttggcggtggtgcggggcagtgcggtcaatcaggacggt gcgtcgaatggtctgacggcgccgaacggtccggcgcagcagcgggtgatccggcaggcc ctggccggcgcagggctccagcccggggatgtcgacgtcgtggaggcgcacggcaccgga acccgtctgggggatccgatcgaggcggaggcgttgatcgcggcttacggggagggtcgg gagcggccgttgttgctggggtcggtgaagtcgaacgtcggtcatgcgcaggcggctgcg ggtgtggcgggtgtgatcaagatggtgctgtcgctgcggcagggtgtggttcccgcgacg cttcatgtggatgagccgacgtgggaggtggactggtcggcgggggccgtggagttggtg cgggagcggcggtcgtggccggaggtcgagcggcctcggcgggcgggggtgtcgtcgttc gggatcagcgggacgaatgcgcatgtgatcttggaggaggcgccgctggtcgaggagccg gtggttgtcggtgactcggtactgggcgttgtgccgtgggtggtctcggctcggagtgag gcggcgttgcggggccaggcccagcggctggtggcgcatgaggaagccgctgttgtggat gtgggctactccctggcgacttcgcgttcgctgctggatcaccgggctgtggttctcgga agtgaccgggagtcattgttggcgggggtccgtgctctggccgagggtcgggagacggca ggtgtcgtacgaggccacagcggtggtgttcgccgtgctgtgttcgtgttcccggggcag gggtcgcagtgggtggggatggctgcgggtctgctggaggaatccgagaccttccgggac cagatcgtcgcgtgcgatgaggtgctggcgccgttgacgggctggtcgctggtcgatgtt ctgcgtggggtggacggctcgccggggcttgagcgggttgatgtggtgcagccggtgttg tgggctgtgatggtgggtctgggccggttgtggcggtcgttgggtgtcgagccggcagct gtggtggggcattctcagggtgagatcgcggcggctgtggtggctggggtgttgtcgctg gaggacggtgcccgggtggtggctgagcgcagccgtctgctgaatgtgttgtcgggtcgg ggcgggatggtgtcggtgccgctgccggtggatgcggtacggctgttgctggtgccgtgg tccggggctgtcggtgtcgctgcggtgaacgggcctcgttcggtgacggtgtccggtgat gtggcggcgctggaggagttgctggcccggtgtgaggccgatggcatcgacgcgcgcagg gtcgcggtggactatgcctcgcactcggctcatgtcgaggacatacaggccgagttgctg gacgcgttggcgccggtggtgatgaggaaggcggaggttcccttctactcgacggtgacc gctggtctgctggagaccggtggtctggatgccgggtactggtaccgcaatctgcgtcag acggtggaactggaggagacggtacgggggctggcagaggacggcttcgacgcgttcatc gaggtcagtcctcacccggtccttgtccccccggtccaggacacactcgaggaggccctc gatgacaggggcgtcgtcctgggtaccctccgccgagacgaaggcggcctcggccggttc accacctccctcgcccaggcccatgtacagggcatcggcgtggattgggccgagttcttc acgaacacgggagcgctgcgggtggacctgccgacctacagcttccaacacgaccgctac tggctggacctccccaccagccgcgacgtatccggggcaggcttgtcatcgccgaatcac ccgttgctcggcgcggtggtcaccgatccggagtcgggcggagtgacgctgacgggccgt ctgtcgctcacggatcagccctggctggcagaccacacgatcgcgggtacgacgatcctg cccgggaccgccttcgtggaactggtggtccgggcgggcgacgaggtggactgcggcgag gtcgaggaactcgccctgcacacgccgctggtgctgtcgtcggcgggcggaacacaggtc caggtccaggtgggcggcccggacgaggacggccgtcgtacggtcgccgtccatgctcgc cccgagtcggccgcggctgacggcggcccggctcacggatggacccgccacgcaagcggc accctgaccccaacccccaccgcacccgacacgacccaccccctcacaccctggccaccg gagaacgcgatccccgtccctgtcacggacatgtacgaggacttcgcagcccgcggctac gcctacggcccggccttccagggcatacaagcggcctggcgacgcggcgacgaggtcttc gcggaggtggctctccccgagcacaccgtgcccgaggcagccgagtacggtctgcacccc gcactgctcgacgcagccctccaggcaaccgggttcctgcccgagaccggccccgatgcc gaccccgacaccgcattcgatacgccgaagctcccgttcgcctggaccggagtcacgcta cgggctctcggtgccaccaggctccacgtacatctgcgccgggccgccgaaggcggagtg gtgatccggaccaccgaccccgacggcacccccgtcgcttcggccgacgccgtaaccatg cgcccggtccccgactccgtcctgtcctcgggattcacacccgccacggcgcacgacctg ttcaccgtggagtggtccacgccgccgaccgtcacgagcccctcgttcccgagctgggct ctggcagaaaacctcacggccacccccacaaccacccccatgaccaccccgacaaccacg gatgtggtgttcgccctgtgcccctccggcccggacacccgctcggtgaccacccaggta ctcgactggatccaggcttggacgaccgccgccgaccgcgacgcgacccgtttggtcctc gtcacgcgaggcgccgtggccgaagggccaggggatccggttcccagcctggaacaggcc ggagtctggggcttggtgcgctccgccgcggtcgagcacccgggccgtttcgcactggtg gacctggacccggacgccaccgcccccgacgacgagacgtggaccacgctggctggccac ctcaccaccgaaccggaactggccctacgcgacaaccgcgtcctggccccccgcctgacc cgctccgctgccccacagataccgccaggttccgaactgcgtctgacgagcgacggctca ggctccgtggcgggtctgcgttgtgccccgcaggcacaacccgtacgaccgctgcgcccc ggcgaggtccgggtcgccgtccgcgcggcgggcctcaacttccgtgacgtactggtcgcc ctgggagtcgcgggcctcggcgaggccggcatgggcggcgagggcgcgggcgtggtcctg gaaatcggggaggacgtacctgacctcgctcctggcgaccgagtgatgggcatccttggg caggcgttcggttccacgacggtggccgatcaccggctcctggtccgcgtcccgtccggc tggtcgttcgcggaggcggcgtcggttccggtcgtgttcgcgacggcgtactacggtctc gtggacctggcaggggtcaagcccggcgaacgcgtcctggtccacgctgccgcaggcggc gtcggcatggcggccgtgcaactggcccgccacctgggcgcggaggtcttcgggacggcg agcccccagaaatgggaggcactcaccactctcggactgagcgccggtcatatcgcctcc tcccgcacgctggaattcgaacccgaattcatgacgaccaccgacaacgagggtgtagac ctggtcctgaacagcctggccggtgaattcaccgatgcttccctgagactgttgtcaccg ggcggccgtttcctggaaatgggcaagaccgacatccgcacgcccgagcagatcactgtc cttcgccccgaagtgacctaccgggcattcgacttgatggatgccggatacgaacggatc ggggagattctgcgcgaggtcatggcactgttcgagcggggggttctgcgcttgccgccg attcgtgcctgggacatccgtcatgccgccgaggccttccggttcatgagccaggcccgg cacatcggcaagaacgtcctgaccattcccgtcccgccgagtcctcaaggaaccacactg atcaccggcggaaccggagagatcggcggtttggtcgcgcggcgtatggcggcggccggt gccgagcacgtgctgctgaccagccggcggggcatggaggctccgggtgccgtcgaactg gtcgcggaactcgaagcgctgggtgctcgggtgactgtgtcggcgtgcgacatgggcgac cgtcagcaggcggcggtgctgttggagggcattcccgcggaccgtcccctcaccgccgtg atccatgcggcgggtgtggtggacgacggagtgctcggctcgctgacgccggagcatgtc gactcggtattccggccgaaggtggacgcggcctggcatctgcacgagctgacccgggag atggacctgtcggccttcgtcctgttctcctccctcgccggtgtcacgggagccgcgggc caggcgaactacgcggccgcgaacaccgctctcgacgcgctcgccgcccaccgccacgcc caaggcctccctgccatctccctggcctggggtttctgggagcaggccagcggtatgacg ggacacctcggcgggagcgacctggcccgaatggcgaggggcggagtcctgcccctgtcc tcggaacagggcctgaacctcctcgacaccgccctggccctacccatccctctggcagcc ccggctcgcctcgatctgtcggcgatccgtgcctcggacgacgtaccccccatcctccga gccctggctctgtccggtaccggccgcccccaggcgtcccgtacccccgccgtcgccaag cccacaggggacgacacactcgccgcgcgcctgactgctctcccggacgccgaccggcac ggcctgctgttggacatcgtccgcactcatctctcggtggtcctgggccacacggacccc gcaaccctcgacgtcgaccgcgccttcaaggaactcggcatcgactccctgaccgcgatc gaactccgcaaccgcctcaacaccgccaccggactccgcctgccccccaccctcgtcttc gaccagcccaccgccaccgccctggcccgccatctccagcagctcctgctccccaaggcc acaccggacaccgtgcacacggacctcgacagactggagaacctcctcgccgaactcgcc acggacggcggcggcacgggagccatggaacagatcgcgcgacggctgcgccagatggcg gcgggcctctccggcgagggcgagcccgcacccgccgaggacctcgaaacggcgaacgcg gaagaaatgctcgcgctcatcagaaacgaattcggcatgcccggcaacgcagagggaatc gggtga

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