Streptomyces graminofaciens: SGFS_035640
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Entry
SGFS_035640 CDS
T09325
Name
(GenBank) 2-oxoisovalerate dehydrogenase
KO
K00167
2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:
1.2.4.4
]
Organism
sgrf
Streptomyces graminofaciens
Pathway
sgrf00280
Valine, leucine and isoleucine degradation
sgrf00640
Propanoate metabolism
sgrf00785
Lipoic acid metabolism
sgrf01100
Metabolic pathways
sgrf01110
Biosynthesis of secondary metabolites
sgrf01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sgrf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
SGFS_035640
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
SGFS_035640
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SGFS_035640
Enzymes [BR:
sgrf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
SGFS_035640
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Motif
Pfam:
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
BBC32270
UniProt:
A0ABN5VI70
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Position
4046049..4047020
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AA seq
323 aa
AA seq
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MTRATIVQALNSALRAALEEDPRTLVMGEDVGRLGGVFRVTEGLQKDFGEERVFDTPLAE
SGIVGTALGLALRGYRPVLEIQFDGFVYPAFDQIVSQLAKMHARALGKVRLPVTIRIPYA
GGIGAVEHHSESHEALFAHTAGLRVVTPSNSDDAHWMLRQAIADDDPVIFLEPKRRYWDK
GEVGPAPARSLHEAAVVRPGRDLTLLAYGPMVKVCLDAADAALAEGRRLEVVDLRSLSPV
DFGTLQRSVERTRRAVVVHEAPVFLGMGAELAARLHERCFYDLEAPVLRVGGFHAPYPPS
RVEEAYLPDLDRVLEAVDRAIAY
NT seq
972 nt
NT seq
+upstream
nt +downstream
nt
atgacccgggccacaatcgtccaggcgctcaattcggcactgcgcgcggcgctcgaggag
gaccccaggacgctggtcatgggagaggacgtaggccgtctcggcggtgtcttccgggtc
accgaaggcctgcagaaggacttcggcgaggaacgggtcttcgacaccccgctggccgag
tcggggatcgtcggcaccgccctcgggctggccctgcgcggctaccggccggtgctggag
atccagttcgacgggttcgtctacccggccttcgaccagatcgtcagccagctggccaag
atgcacgcccgcgcgctgggcaaggtcaggctccccgtgacgatccgcatcccgtacgcg
ggcggcatcggcgcggtggagcaccacagcgagtcccacgaggcgctgttcgcgcacacc
gcggggctgcgcgtggtgactccgtcgaacagcgacgacgcgcactggatgctgcggcag
gcgatcgccgacgacgatccggtgatcttcctcgagcccaagcggcggtactgggacaag
ggcgaggtgggtccggccccggcccgctccctgcacgaggcggcagtggtccggcccggc
cgggacctgacactgctcgcgtacgggccgatggtcaaggtctgcctggacgccgcggac
gcggcgctggcggagggccgcaggctggaggtggtggacctgcgctcgctgtcacccgtg
gacttcggcacgctccagcggtccgtggagcggacccggcgggcggtggtggtgcacgag
gcgccggtgttcctcggcatgggggcggagctggctgcccggctgcacgagcggtgcttc
tacgacctggaggcgccggtgctgcgggtcggcgggttccacgcgccctatccgccgtca
cgggtggaggaggcgtacctgcccgatctggaccgggtgctggaggccgtggaccgggcc
atcgcctactga
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