Streptomyces graminofaciens: SGFS_085130
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Entry
SGFS_085130 CDS
T09325
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sgrf
Streptomyces graminofaciens
Pathway
sgrf00300
Lysine biosynthesis
sgrf00550
Peptidoglycan biosynthesis
sgrf01100
Metabolic pathways
sgrf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sgrf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SGFS_085130
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SGFS_085130
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SGFS_085130
Enzymes [BR:
sgrf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SGFS_085130
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
BBC37219
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Position
9464411..9465817
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AA seq
468 aa
AA seq
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MIALSLAEIAEVVGGQTHDIPDPSVQVTGPVVRDSRDVGPGSLFVAFVGERVDGHDYAAA
VVEAGAAAVLASRPVGVPAIVVRDVQTALGALARHVVTKLGTTLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPGSLNNEIGLPLTALSATEETRFLVLEMGARGIGHIRYLTDLTPPKV
GLVLNVGTAHIGEFGGREQIAEAKGELVEALPEDGAAILNADDPLVRAMASRTKARVILF
GESDEADVRAENVRLTDAGQPAFRLHTPSGASDVTMRLYGEHHVSNALAAAAVAHELGMS
AEEIATALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALAAMGKGRRTWA
VLGKMAELGDESLAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEESVHVS
DAQAAVDLLRSQLRPGDVVLVKASRSVGLESVAQALLDSGNEGEVAAR
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctctctcgccgagatcgcagaagtcgtcggcgggcagacccacgacata
ccggatccgtcggtccaggtcaccggaccggtcgtccgggactcccgcgacgtggggccc
ggcagcctcttcgtcgccttcgtcggcgagcgcgtcgacggacacgactacgcggccgcg
gtcgtcgaggcgggcgcggcagcggtgctggcgtcccgccccgtcggcgtgcccgcgatc
gtcgtacgggacgtccagacggccctcggcgccctcgcccggcacgtcgtgacgaagctc
ggcacgaccctcgtggccctcaccggctccgcgggcaagaccagcaccaaggacctgatc
gcccaggtgctccggcgcaaggcgccgaccgtcttcacgcccggctccctcaacaacgag
atcgggttgccgctcaccgccctcagcgccaccgaggaaacccgtttcctcgtcctggag
atgggcgccagaggcatcggccacatccgctacctcaccgatctgaccccgccgaaggtc
ggcctcgtcctcaatgtcggcaccgcccacatcggcgagttcggcggccgggagcagatc
gccgaggcgaagggcgagttggtcgaggccctgccggaggacggcgccgcgatcctcaac
gccgacgaccccctcgtacgcgcgatggcatcccgtacgaaggccagggtgatcctcttc
ggagagtccgacgaagcggacgtacgggcggagaacgtacggctcacggacgccggacag
cccgccttcagacttcacacaccctccggtgcaagcgatgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgcagcggccgccgtcgcccatgagctgggcatgtcc
gcggaagagatcgccaccgcgctctccgaggcgggctccctctcccgctggcggatggag
gtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagccgctctgcgcgcgctcgcggcgatgggcaaggggcggcggacctgggcg
gtgctcggcaagatggccgagctcggggacgaatcgctcgccgagcacgacgcggtcgga
cggctagccgtccggctcaacgtcagcaagctcgtcgcggtcgggggcagggaagcgtcc
tggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggcggtcgacctgttgcgcagtcagttgcgcccgggagacgtcgtactc
gtgaaggcgtcccggtcggtcgggctcgagagcgtggcgcaggcgctgctcgacagcggc
aacgagggtgaggttgccgcccgatga
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