Streptomyces griseoaurantiacus: V9K83_24505
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Entry
V9K83_24505 CDS
T10677
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sgrs Streptomyces griseoaurantiacus
Pathway
sgrs00300
Lysine biosynthesis
sgrs00550
Peptidoglycan biosynthesis
sgrs01100
Metabolic pathways
sgrs01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sgrs00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
V9K83_24505 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
V9K83_24505 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
V9K83_24505 (murF)
Enzymes [BR:
sgrs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
V9K83_24505 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
RPAP1_N
Motif
Other DBs
NCBI-ProteinID:
WWY87112
LinkDB
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Position
5595754..5597169
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AA seq
471 aa
AA seq
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MIALSLAEIAEVVGGQTHDIPDPSVMVTGPVVRDSREAVPGSLFVAFVGERADGHDYARA
VVETGAVAVLGSRPVGVPAIVVDDVQRALGALARHVVERLGATLVALTGSAGKTSTKDLI
AQVLRTKAPTVFTPGSLNNEIGLPLTALSATAETRFLVLEMGARGIGHIRYLTELTPPRI
GLVLNVGSAHIGEFGGREQIAQAKGELVESLPPAEEGGVAVLNADDPYVKAMAARTTARV
LLFGESDEADVRAENVTLTAAGQPSFSLHTPSGCSDVTMRLYGEHHVSNALAAAAVAHEL
GMSAKEIATALSEAGSLSRWRMEVTERPDGVTIVNDAYNANPESMKAALRALAAMGRGRR
TWAVLGRMAELGDEALAEHDAVGRLAVRLNVGKLVAVGGREASWLQLGAYNEGSWGEESV
HVSDAQAAVDLLRSELRPGDVVLVKASRSVGLESVAQALLETGAEGEVAAR
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcagaagtcgtcggcgggcagacacacgacata
ccggatccgtcggtcatggtcaccggacccgtcgtccgggactcccgcgaggcggtaccc
ggcagcctcttcgtcgccttcgtcggcgaacgcgcggacggccacgactacgcgcgggcc
gtcgtcgagaccggcgcggtggccgtgctgggctcccggcccgtcggcgtgcccgccatc
gtcgtggacgacgtgcagcgggcgctgggcgccctcgcccggcacgtcgtggaacggctc
ggcgccaccctcgtcgccctcaccggctcggcgggcaagaccagcaccaaggacctcatc
gcccaggtgctgcgcaccaaggcgcccacggtgttcacacccggctcgctcaacaacgag
atcggactgccgctcaccgcgctcagcgccaccgccgagaccaggttcctcgtcctggag
atgggcgcacgcggcatcggccacatccgctacctcacggaactcaccccgccgcggatc
ggtctcgtcctgaacgtcggctccgcccacatcggcgagttcggcgggcgcgagcagatc
gcacaggcgaagggcgaactcgtcgagagcctcccgccggccgaggagggcggcgtcgcg
gtcctcaacgccgacgacccctacgtgaaggccatggccgcccgcaccacggcacgggta
ctgctgttcggggagagcgacgaagcggacgtacgcgccgagaacgtgacgctcacggct
gccggacagccctcgttcagccttcacacaccctccgggtgcagcgatgtgacgatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgtccgcgaaagagatcgccaccgcgctctcggaggcgggctccctctcccgctgg
cgcatggaggtcaccgagcgccctgacggcgtgaccatcgtcaacgacgcctacaacgcg
aaccccgagtccatgaaggcagcgctgcgcgcgctggcggccatgggacgggggcggcgg
acctgggcggtgctcggcaggatggccgagctcggggacgaggcgctcgccgagcacgac
gcggtcggacggctggccgtccggctcaatgtcggcaagctcgtcgcggtcgggggcagg
gaagcgtcctggctgcaactgggcgcatacaacgagggttcgtggggtgaggagtcggtg
cacgtgtccgacgcacaggcggctgtcgacctgttgcgcagcgagttgcgcccgggagac
gtcgtactcgtgaaggcgtcccggtcggtcgggctcgagagcgttgcccaggcgctgctc
gagaccggtgccgagggtgaggttgccgcccgatga
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