Streptococcus gallolyticus subsp. gallolyticus ATCC 43143: SGGB_0629
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Entry
SGGB_0629 CDS
T02018
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sgt
Streptococcus gallolyticus subsp. gallolyticus ATCC 43143
Pathway
sgt00300
Lysine biosynthesis
sgt00550
Peptidoglycan biosynthesis
sgt01100
Metabolic pathways
sgt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sgt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SGGB_0629 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SGGB_0629 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SGGB_0629 (murF)
Enzymes [BR:
sgt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SGGB_0629 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAK27518
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Position
650039..651403
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AA seq
454 aa
AA seq
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MKLTLHEVAKVVGAKNTISEFDDVPLRQIEFDSRKIEKGDLFLPLKGARDGHDFIETAFE
NGAGATFSEREVAGHPYIWVDDCLEAFQALASYYLEKQRVDVIAVTGSNGKTTTKDMIAA
VLSTEYKTYKTQGNYNNEIGLPYTALHMPDDTEKIVLEMGQDHMGDIHLLSELAKPHIGV
VTLIGEAHLEFFGSREKIAEGKLQIVDGMDSDGILIAPADTIVDPYLPESQMVIRFGDGA
EIFVKDLQESKESLTFTTNVIDRPITLPVPGKYNATNAMVAAYVGKLLAISDDDIVEALE
TIELTRNRTEWKKAANGADILSDVYNANPTAMRLILETFSKIPANEGGKKIAVLADMKEL
GEQSVELHKRMIMSLSPETLDTLIFYGEDIAELAQLASQMFPIGKVYYFKKTADEDQFDA
MLETVQKVLQPADQILLKGSNSMQLAKVVEALEE
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaacattgcatgaagtcgccaaggttgttggcgctaaaaatactatttcggag
tttgatgacgttcccctgcgacaaattgaatttgacagtcgtaagattgaaaaaggggat
ttatttttaccattaaaaggcgcgcgtgatgggcatgattttattgaaactgcctttgaa
aatggtgctggtgcgactttttcagaacgtgaagtagctggtcatccatacatttgggtt
gatgattgcctagaggcttttcaagcgctagctagctattatcttgagaaacagcgtgtt
gatgttattgctgtgacagggtcaaatggtaaaacgacaaccaaagatatgattgctgcg
gttttatcaacagaatacaagacttataaaacacaaggcaactacaataacgaaattggt
ttgccatatacagcacttcatatgccagatgatacggagaaaattgtccttgaaatgggg
caagatcatatgggtgacattcatctgttgtcagaacttgcaaaaccacatatcggtgtg
gtgactttgattggtgaagctcatttggaatttttcggtagtcgtgagaaaatcgcagaa
ggtaaattgcaaattgttgatggcatggattcagatggcattttgattgcgccagctgac
acaatcgttgatccttatttacctgaaagccaaatggttattcgttttggtgacggcgca
gaaatttttgtgaaagatttgcaagaaagtaaggaatcgttgacctttacgacaaatgtg
attgaccgtccaattaccctacctgtgcctggaaaatacaatgcgactaatgccatggtg
gcagcttatgttggtaaattattagccatttctgatgacgatattgtcgaggctcttgag
acaatcgaattaacgcgcaatcgtacggaatggaaaaaagcagccaatggtgctgatatt
ttgtcagatgtttacaatgctaatccaacggcaatgcgcttaattttagagacattttct
aaaattcctgccaatgagggtggtaaaaaaatcgctgtgcttgctgacatgaaagaattg
ggtgagcaatctgttgagcttcataaacgcatgattatgagcttgtcacctgaaacatta
gatacactcattttctatggggaagatattgccgagttggcacaacttgctagtcaaatg
ttcccaattggaaaagtttattatttcaagaaaacagctgacgaggatcaatttgatgcc
atgcttgaaactgttcaaaaagtattgcaaccagctgaccaaatcttgttgaaaggtagc
aactcaatgcagttagctaaagttgttgaagcactggaggaatag
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