Streptococcus gallolyticus subsp. gallolyticus ATCC 43143: SGGB_0741
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Entry
SGGB_0741 CDS
T02018
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sgt
Streptococcus gallolyticus subsp. gallolyticus ATCC 43143
Pathway
sgt00290
Valine, leucine and isoleucine biosynthesis
sgt00620
Pyruvate metabolism
sgt01100
Metabolic pathways
sgt01110
Biosynthesis of secondary metabolites
sgt01210
2-Oxocarboxylic acid metabolism
sgt01230
Biosynthesis of amino acids
Module
sgt_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sgt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SGGB_0741 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SGGB_0741 (leuA)
Enzymes [BR:
sgt01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SGGB_0741 (leuA)
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Gene cluster
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Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
BAK27622
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Position
772645..774207
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AA seq
520 aa
AA seq
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MRKVEFLDTTLRDGEQTPGVNFSIKEKVAIAKQLEKWGIASIEAGFPAASPDSFEAVRQI
SAAMTTTAVSGLARSVKSDIDACYEALKDAKYPQCHVFIATSPIHREYKLKKTKEEILDI
IKEHVTYARSKFDVVEFSPEDATRTELDYLLQVVQTAVDAGATYINIPDTVGFTTPEEYG
NIFKYLIENTKSDREIIFSPHCHDDLGMATANTLAAIKNGAGRVEGTVNGIGERAGNVAL
EEIAVALNIREDYYQATSDIVLNETVNTSELISRFSGISIPKNKAVVGGNAFSHESGIHQ
DGVLKNPLTYEIITPELVGVKHNSLPLGKLSGRHAFVEKLKELELAFEESEIATLFGKFK
KLADKKHEITDADIRALVAGTEIENPEGFHFGDLKLTSNADDTVTAEVLMVNADGEEVEV
IANGKGSVEAIYNAVDKFFNQTVRLLSYTMDAVTDGIDSQARVSVSIENVDTGTIFNASG
IDFDVLKAGAIAYVNANAFVQKENAGEIGKAVSFRDVPTN
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgcgtaaagttgaattccttgataccactcttcgtgatggtgaacaaacgccaggcgtt
aatttttcaatcaaagaaaaagtagcaattgccaaacagcttgaaaaatggggtattgct
tcaattgaagctggttttccagcagctagtcctgattcatttgaagcggttcgtcaaatt
tcagcagcaatgacaacaactgcggtgtcaggtttagcacgttctgtgaaatcagatatt
gatgcttgttatgaagcattgaaagatgctaaatacccacaatgtcacgtgttcattgca
acaagtcctattcatcgtgaatataaattgaaaaaaacaaaagaagaaattcttgatatt
atcaaagaacatgtgacttatgcacgcagtaaatttgatgtggtcgaattttctccagaa
gatgcaacccgtacagaacttgattatcttctccaagttgttcagacagcggttgatgct
ggtgcaacttacatcaatattcctgatacggttggtttcacaacgccagaggaatatggt
aacatcttcaaatatttgattgaaaatacaaaatcagaccgcgagattatcttcagtcca
cattgtcatgatgaccttggaatggcgacagccaacactttggcagctatcaaaaatggt
gctggacgcgttgaagggacagtcaatggtattggtgaacgtgctggaaatgtggcactt
gaagagattgcagtagctcttaatatccgtgaagattattatcaagcgacatctgatatt
gtccttaacgaaacggtcaatacgtctgaattgatttcacgcttctcaggaatttcaatt
cctaagaacaaagctgtggttggtggaaatgccttctcacacgaatctggtattcaccaa
gatggtgtgcttaaaaatccactcacttatgaaattatcacgccagagcttgtcggtgtc
aaacacaactcgcttccgcttggtaaactttcaggtcgtcatgctttcgttgaaaaattg
aaagaactcgaacttgctttcgaagaatcagaaattgcaacgctatttggtaaatttaaa
aaattggctgataagaaacatgaaattacagacgctgatatcagagctttggttgctgga
acagaaattgaaaatccagaaggcttccactttggcgatttgaaattaacatcaaatgct
gatgatacggtgacagctgaagtacttatggtaaacgctgacggtgaagaagttgaagtt
atcgcaaatggaaaaggttctgttgaagctatctataacgctgtcgataaattcttcaat
caaactgtccgccttctcagctacacaatggatgctgtaacagacggtattgattcacaa
gcgcgtgtgtctgtttcaattgaaaatgttgatacaggaacaattttcaacgcatctggt
attgattttgacgtgcttaaagcaggtgctattgcttatgtcaatgcgaatgcttttgtt
caaaaagaaaatgctggtgaaattggcaaagccgtttcattccgtgatgtgccaactaat
taa
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