Streptococcus gallolyticus subsp. gallolyticus ATCC 43143: SGGB_0744
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Entry
SGGB_0744 CDS
T02018
Symbol
leuC
Name
(GenBank) 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sgt
Streptococcus gallolyticus subsp. gallolyticus ATCC 43143
Pathway
sgt00290
Valine, leucine and isoleucine biosynthesis
sgt00660
C5-Branched dibasic acid metabolism
sgt01100
Metabolic pathways
sgt01110
Biosynthesis of secondary metabolites
sgt01210
2-Oxocarboxylic acid metabolism
sgt01230
Biosynthesis of amino acids
Module
sgt_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sgt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SGGB_0744 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SGGB_0744 (leuC)
Enzymes [BR:
sgt01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SGGB_0744 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
SGGB_0744 (leuC)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
BAK27625
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All DBs
Position
775616..777004
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AA seq
462 aa
AA seq
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MSGKSIFDKLWERHVVTGEEGEPQLMYVDQHYIHEVTSPQAFQGLRDAGRKVRRPDLTFG
TTDHNVPTVDIFNIRDLVSKNQIDTLARNVKDFGIDAATHGTERQGIVHMVGPETGRSQP
GKFVVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQCIWQVKPKKMKVEFVGKPQKGVYS
KDFILALIAQYGVDAGVGYAVEYCGEAIDALSMDERMTIANMSIEFGAKMGLMNPDQKTF
DYVKGREAAPKGDKFEQAVEDWKTLVSDPDAEYDKVITIDVSGLAPMVTWGTNPEMGVEF
GKPFPEIKDMNDERAYHYMDIKPGDKAEDIDLGYVFIGSCTNARLSDLELAAKIVKGKHI
SPNLTAIVVPGSRPVKKEAERLGLDKIFMDAGFEWREPGCSMCLGMNPDHVPEGVHCAST
SNRNFEGRQGFGACTHLCSPAMAAAAAIAGKFIDVRQLSEVQ
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgagcggaaaatcgatttttgataagctttgggaacgccatgtggttactggtgaagaa
ggcgaaccacagcttatgtatgttgaccagcactatattcatgaagtaacaagtccgcag
gcattccaaggacttagagatgcaggtcgtaaagtacgtcgcccagatttaacatttgga
acgactgaccacaatgttccaacggtagatattttcaatattcgcgacttggtgtcaaaa
aatcaaattgatactcttgctcgaaatgttaaagactttggtattgatgcggcaacacat
ggaacagaacgccaagggattgttcatatggtaggtccagaaacaggacgtagtcaacct
ggtaaatttgttgtctgcggggacagccatacggcaactcacggtgcttttggggcaatt
gcctttggtattggaacatctgaagtggagcacgtttttgcaacacagtgcatttggcaa
gtaaaaccaaagaaaatgaaagttgaatttgtcggcaaaccacaaaaaggtgtttattca
aaagactttatccttgctttgattgctcaatatggtgttgatgctggtgtaggctatgcg
gttgagtattgtggtgaagccattgatgctctttcaatggatgaacgcatgaccattgca
aacatgtcgattgaatttggagcaaaaatgggcttgatgaatccagaccaaaagaccttt
gattacgttaaaggtcgtgaagcggcgcctaaaggtgataaattcgagcaagcggtcgaa
gattggaaaacattggtttctgaccctgatgccgaatatgataaagttattaccattgat
gtttcaggattggcaccaatggtgacttggggaacaaaccctgaaatgggtgttgaattt
ggcaaaccgttcccagaaatcaaagacatgaatgatgaacgtgcttatcattatatggac
attaagcctggtgataaagctgaagatattgatttgggttacgttttcattggttcttgt
accaatgcgcgtctatcagaccttgaattagcagctaagattgtcaagggcaaacatatt
tcaccgaatctgacagctattgttgttcctggttctcgtcctgttaagaaagaagcagag
cgactagggcttgataaaattttcatggatgctggttttgaatggcgtgagcctggttgt
tcaatgtgtcttggaatgaacccagaccatgtgccagaaggtgttcattgtgcctcaaca
agtaatcgtaactttgaagggcgtcaaggttttggagcgtgtacacatctttgtagccca
gctatggcggcagcggcagcaattgctggtaaattcatcgatgttcgccaactgtcagaa
gttcagtaa
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