Streptomyces glaucescens: SGLAU_19035
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Entry
SGLAU_19035 CDS
T03327
Symbol
ilvD
Name
(GenBank) Dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
sgu
Streptomyces glaucescens
Pathway
sgu00290
Valine, leucine and isoleucine biosynthesis
sgu00770
Pantothenate and CoA biosynthesis
sgu01100
Metabolic pathways
sgu01110
Biosynthesis of secondary metabolites
sgu01210
2-Oxocarboxylic acid metabolism
sgu01230
Biosynthesis of amino acids
Module
sgu_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
sgu_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
sgu00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SGLAU_19035 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
SGLAU_19035 (ilvD)
Enzymes [BR:
sgu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
SGLAU_19035 (ilvD)
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
DUF4154
Motif
Other DBs
NCBI-ProteinID:
AIR99767
UniProt:
A0A089X771
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Position
4342216..4344069
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AA seq
617 aa
AA seq
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MPELRSRTVTHGRNMAGARALMRASGVPGADIGRKPIIAVANSFTEFVPGHTHLQPVGRI
VSEAIREAGGIPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALVCI
SNCDKITPGMLMAALRLNIPAVFVSGGPMESGRATLVDGTVRTLDLVDAISDAVNDKISD
EDILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARRALYENAART
VMDITRRYYEQDDDSVLPRNVATFAAFENAMALDIAMGGSTNTILHLLAAAQEAGVPFGL
AEIDAVSRRVPCLAKVAPNVAKDRTYYMEDVHRAGGIPALLGELHRAGLLNEDVHAVHSP
SLSDWLKTWDVRGGSPSPEAVELWHAAPGCVRSAEAFSQSERWEALDTDAENGCIRSAEH
AYSKDGGLAVLKGNLAVDGCVVKTAGVDESIWTFEGPAVVCESQEEAVEKILNKQITHGD
VVVIRYEGPKGGPGMQEMLYPTSFLKGRGLGKTCALITDGRFSGGTSGLSIGHASPEAAS
GGTIALVQDGDRIRIDIPNRSIELLVDEAELARREQALDGVYAPRNRDRKVSAALRAYAA
MATSADKGAVRDVGKLG
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagctgaggtcccgcacagtcacccacggccgcaacatggcgggcgcccgcgcc
cttatgcgcgcctccggtgtacccggtgcggacatcggccggaagccgatcatcgcggtc
gccaacagcttcaccgagttcgtgcccggccacacccacctccagccggtcggccggatc
gtcagcgaggcgatcagggaggcgggcggcatcccgcgcgagttcaacacgatcgccgtc
gacgacggcatcgcgatgggccacggcggcatgctctacagcctgccctcccgcgacctg
atcgcggacagcgtggagtacatggtggaggcgcactgcgccgacgccctggtctgcatc
tccaactgcgacaagatcaccccgggcatgctgatggcggccctgcgcctcaacatcccc
gcggtcttcgtctccggcggccccatggagtccggccgcgccaccctggtcgacggcacg
gtccgcaccctcgacctggtcgacgcgatctccgacgccgtgaacgacaagatctcggac
gaggacatcctccgcatcgaggagaacgcctgtccgacctgcggctcctgttccggcatg
ttcaccgccaactcgatgaactgcctgaccgaggccatcggcctgtccctccccggcaac
gggtccgtcctggccacccacaccgcccgccgcgcgctctacgagaacgccgcccgcacg
gtcatggacatcacccgccgctactacgagcaggacgacgactcggtcctgccccgcaac
gtcgccaccttcgccgccttcgagaacgcgatggccctcgacatcgcgatgggcggctcc
accaacacgatcctgcacctgctggccgccgcccaggaggccggcgtcccgttcggcctg
gcggagatcgacgcggtgtcccgccgggtcccgtgcctggccaaggtcgcgcccaacgtc
gccaaggaccgcacgtactacatggaggacgtgcaccgcgcaggcggcatccccgccctg
ctcggcgaactgcaccgcgcgggcctgctcaacgaggacgtgcacgccgtgcacagcccg
tccctgtcggactggctcaagacctgggacgtgcgcggcggctccccgtcccccgaggcc
gtcgagctgtggcacgccgcccccggctgcgtccgctccgccgaggccttctcccagtcg
gagcgctgggaggccctcgacaccgacgccgagaacggctgcatccgctccgccgagcac
gcctactccaaggacggcggcctcgcggtcctcaagggcaacctcgcggtcgacggctgc
gtggtgaagacggccggcgtcgacgagtcgatctggaccttcgagggccccgccgtcgtc
tgcgagtcgcaggaggaggccgtcgagaagatcctcaacaagcagatcacccacggcgac
gtggtcgtcatccgctacgagggcccgaagggcggccccggcatgcaggagatgctctac
ccgacgtccttcctcaagggccgcggcctcggcaagacctgcgcgctgatcaccgacggc
cggttctccggcggcacctccggcctgtccatcggccacgcctccccggaagcggcgtcc
ggcggcaccatcgcgctcgtccaggacggcgaccgcatccgcatcgacatcccgaaccgg
tcgatcgagctgctggtcgacgaggccgaactggcccgccgcgagcaggccctcgacggc
gtctacgccccgaggaaccgcgaccgcaaggtctcggccgccctgcgcgcgtacgccgcg
atggccaccagcgccgacaagggcgcggtccgcgacgtcggcaagctgggctga
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