Streptomyces glaucescens: SGLAU_19175
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Entry
SGLAU_19175 CDS
T03327
Name
(GenBank) uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sgu
Streptomyces glaucescens
Pathway
sgu00860
Porphyrin metabolism
sgu01100
Metabolic pathways
sgu01110
Biosynthesis of secondary metabolites
sgu01120
Microbial metabolism in diverse environments
sgu01240
Biosynthesis of cofactors
Module
sgu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sgu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sgu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SGLAU_19175
Enzymes [BR:
sgu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SGLAU_19175
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SGLAU_19175
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Zn_ribbon_PRDM4
Motif
Other DBs
NCBI-ProteinID:
AIR99792
UniProt:
A0A089X7A0
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All DBs
Position
4374041..4375756
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AA seq
571 aa
AA seq
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MSPTTLPACPDHGHVTFLGAGPGDPGLLTLRAVEALASADVLVAEHEVLDVVRVHARPGV
AVVNTDPDPAGPSADRLPGTGTPQLTVVDGTSTPVAAPAERDAAHLVMEAARGGRRVVRA
VSGDPGLDAYAAEEMLACAAAGVPFEVVPGVAAAVGVPAYAGVPLRDADGADVRFVDART
ASDRCWTEVGASDGTVVVSTTLDSVAAAAGELVAAGRKPDTPLTVTVAGTTTRQRTWTAT
LGTIAQTLKQAKVLPSPEGGRPVIAVVGERSAAARRDQLSWFESKPLFGWKVLVPRTKEQ
AASLSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVRE
KFEEYGLDARAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFD
PIDRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLF
TSSSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALAEFG
MRRRAAALEAGDPVTRPSERRPGARRRRTTT
NT seq
1716 nt
NT seq
+upstream
nt +downstream
nt
gtgagccccaccacccttcccgcctgtcccgaccacgggcacgtcaccttcctgggtgcc
ggacccggagacccggggctgctgaccctgcgcgccgtggaggcgctggccagcgcggac
gtcctcgtcgccgagcacgaggtgctcgacgtcgtgcgcgtccacgcccggccgggcgtc
gccgtcgtcaacacggatccggaccccgcgggtccgtccgcggaccggcttccgggcaca
ggcacgcctcagctcacggtggttgacggcacgtcaacacccgtcgccgcacccgcagaa
cgggatgccgcacatcttgtcatggaggccgcgcggggcggcaggcgggtcgtgcgtgcc
gtctccggcgaccccggactcgacgcgtacgccgccgaggagatgctcgcctgcgccgcc
gctggggtccccttcgaggtggtccccggggtcgccgccgccgtcggcgtgcccgcctac
gcgggtgtgccgctgcgcgacgccgacggcgcggacgtgcggttcgtcgacgcgcgcacg
gcgtccgaccggtgctggaccgaggtgggcgcctccgacgggacggtcgtggtgtccacg
acgctcgactccgtggccgccgccgcgggcgagctggtcgccgccggccgcaagcccgac
accccgctgacggtgaccgtcgccggcaccaccacccggcagcgcacctggacggcgacc
ctcggcaccatcgcccagacgctgaagcaggccaaggtgctgccctcgcccgagggcggc
cggccggtgatagccgtggtcggtgagcgcagcgccgccgcccggcgtgaccagctctcg
tggttcgagtccaagccgctgttcggctggaaggtgctcgtgccgcgcacgaaggagcag
gcggcgtcgctctccgaccagctgcggtcctacggtgccgtgccgcacgaggtgccgacc
atcgcggtcgagccgccgcgcacgccccagcagatggagcgggcggtcaagggcctggtc
accggccgctacgagtggatcgccttcacctcggtgaacgcggtcaaggccgtccgggag
aagttcgaggagtacgggctcgacgcgcgtgccttcgccgggatcaaggtcgccgcggtc
ggcgagcagaccgccaaggcgctgatcgccttcggcgtgaagcccgacctggtgcccagc
ggcgagcagtcggccgccggactcctggaggactggccgccctacgacccggtcttcgac
ccgatcgaccgcgtcttcctgccgcgcgccgacatcgccaccgagaccctggtcgccggg
ctcatcgagctgggctgggaggtcgacgacgtcaccgcctaccggaccgtgcgcgcctcg
ccgccgccggccgagacgcgggaggcgatcaagggcggcggtttcgacgcggtgctgttc
acgtcgtcgtcgaccgtgcggaacctggtcggcatcgccggcaagccgcacaacgtgacc
gtcatcgcctgcatcgggcccgccacggcgaagaccgccgaggagcacgggctgcgggtc
gacgtgatggcgcccgaaccgtccgtgcacaagctcgccgaggcgctggccgagttcggc
atgcgccgccgggccgccgccctggaggccggcgacccggtgacccggccgagcgagcgg
cgtccgggggcgcgcaggcggcgtacgacgacctga
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