Streptomyces gardneri: H4W23_10550
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Entry
H4W23_10550 CDS
T07252
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sgx
Streptomyces gardneri
Pathway
sgx00300
Lysine biosynthesis
sgx00550
Peptidoglycan biosynthesis
sgx01100
Metabolic pathways
sgx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sgx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
H4W23_10550 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
H4W23_10550 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
H4W23_10550 (murF)
Enzymes [BR:
sgx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
H4W23_10550 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
QPK45021
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Position
complement(2338222..2339646)
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AA seq
474 aa
AA seq
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MIALSLAEIAEIVGGQTHDIPDPAARATGPVVIDSREVRPGSLFVAFAGEHVDGHDYAER
AVEAGAAAVLAARPVGVPAIVVDDVQAALGALARAVVRRLGTDVVALTGSAGKTSTKDLI
AQVLDRHAPTVWTPGSLNNEIGLPLTALKATDETRHLVLEMGARGIGHIRYLTGLTPPRI
GLVLNVGTAHIGEFGGREQIAEAKGELVECLPSAEEGGVAVLNADDPLVRAMESRTKARV
ILFGEADEAAVRAENVLLTENGQPSFRLHTPTGCSDVTLRLYGEHHVSNALAAAAVAHEL
GMPVEEIATALSEAGTLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALASMGRAAQ
ARGARTWAVLGKMAELGDASLVEHDAVGRLAVRLNVSKLVAVGDREASWLQLGAYNEGSW
GEESVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLERVALALLDTEGEVAGR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccgaaatcgtcggcgggcagacgcacgacata
ccggatccggccgcccgggcgaccgggcccgtcgtcatcgactcccgcgaggtgcggccc
ggcagcctcttcgtcgccttcgccggcgagcacgtcgacggccacgactacgcggagcgc
gccgtcgaggcgggagcggcggccgtactcgccgcccgccccgtcggcgtccccgcgatc
gtcgtggacgacgtccaggccgcgctgggggccctcgcccgcgcggtcgtccggcggctc
ggcaccgatgtcgtcgccctcaccggctccgccggcaagacctccacgaaggacctgatc
gcccaggtcctcgaccggcacgcgcccaccgtgtggacgcccggttccctcaacaacgag
atcggcctgccgctcaccgcgctgaaggccaccgacgagacccggcacctggtcctggag
atgggcgcccgcggcatcgggcacatccgctacctcaccggcctcaccccgccccgtatc
ggcctcgtcctgaacgtgggcaccgcccacatcggcgagttcggcggccgggagcagatc
gccgaggccaagggcgagctcgtcgagtgcctgccctccgccgaggagggcggtgtcgcg
gtcctcaacgccgacgacccgctcgtccgcgcgatggagagccgcaccaaggcccgcgtg
atcctcttcggcgaagcggacgaagcggccgtacgggccgagaacgtcctcctcacagag
aacggacagccttctttcaggcttcacacacccaccgggtgcagtgacgtgaccttgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcgcacgagctg
ggcatgcctgtcgaagagatcgccaccgcgctctccgaggccggcaccctgtcgcgctgg
cgcatggaggtcaccgagcgtccggacggcgtgacgatcgtcaacgacgcctacaacgcg
aatcccgagtccatgcgagccgccctgcgcgcgctcgcgtccatggggcgggccgcacag
gcccgaggggctcgtacgtgggcggtgctcggcaagatggccgagctcggtgacgcatcg
ctcgtcgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtc
gcggtcggggacagggaagcgtcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcaggcggctgtcgacctgttgcgcagtgag
ctgcgcccgggggatgtcgtccttgtgaaggcttccaggtcggtcggtctcgaacgggtc
gcgctggccctcctcgacaccgagggcgaggttgccggacgatga
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