Streptomyces globosus: C0216_00340
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Entry
C0216_00340 CDS
T06864
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sgz
Streptomyces globosus
Pathway
sgz00280
Valine, leucine and isoleucine degradation
sgz00640
Propanoate metabolism
sgz00785
Lipoic acid metabolism
sgz01100
Metabolic pathways
sgz01110
Biosynthesis of secondary metabolites
sgz01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sgz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
C0216_00340 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
C0216_00340 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
C0216_00340 (pdhA)
Enzymes [BR:
sgz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
C0216_00340 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AXE22091
UniProt:
A0A344TTX0
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All DBs
Position
71414..72628
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AA seq
404 aa
AA seq
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MTVESTAARKPRRSSGTKRAAGAASAAKAPAAKAAATPQNTEPQLVQLLTPEGERIGAAE
NPDNAEFAAFVEDITTEDLRGLYRDMVLTRRFDGEATALQRQGELGLWASLLGQEAAQIG
SGRALRDDDYVFPTYREHGVAWCRGVDPTNLLGMFRGVNHGGWDPNGNNFHLYTIVIGSQ
TLHATGYAMGVAKDGADSAVIAYFGDGASSQGDVAEAFTFSAVYNAPVVFFCQNNQWAIS
EPTERQMRVPLYRRAEGFGFPGVRVDGNDVLACLAVTRWALDRARRGEGPTLVEAYTYRM
GAHTTSDDPTRYRRDEERQAWEAKDPILRLKAHLLASGGADEAFFEELETESEALGKRVR
EVVRAMPDPDTMAIFENVYADGHALVDEERAQFAAYLASFEEGH
NT seq
1215 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgcgcgcaagccgcgacgcagcagcggcaccaagcgggcg
gcaggcgccgcgagcgccgccaaggcccccgcagccaaggccgccgccaccccgcagaac
accgagccgcagctcgtacagctgctgacgcccgagggcgagcgcatcggcgcggcggag
aaccccgacaacgcggagttcgcggccttcgtcgaggacatcaccaccgaggacctgcgc
gggctctaccgcgacatggtcctcacccgccgcttcgacggcgaggccaccgccctgcag
cgccagggcgagctgggcctgtgggcctcgctgctcggccaggaggccgcccagatcggc
tccggccgcgccctgcgcgacgacgactacgtcttcccgacctaccgcgagcacggggtg
gcatggtgccgcggggtcgacccgacgaacctcctcggcatgttccgcggcgtgaaccac
ggcggctgggaccccaacggcaacaacttccacctgtacacgatcgtcatcggctcccag
acgctccacgcgaccgggtacgcgatgggcgtggccaaggacggcgccgactccgcggtc
atcgcctacttcggcgacggcgcgtccagccagggcgacgtcgccgaggccttcaccttc
tcggccgtctacaacgcccccgtggtgttcttctgccagaacaaccagtgggcgatctcc
gagccgaccgagcgccagatgcgcgtgccgctctaccgccgcgccgagggcttcggcttc
cccggcgtccgcgtcgacggcaacgacgtcctcgcctgcctcgcggtcacccgctgggcc
ctggaccgcgcccgccgcggcgagggcccgacgctcgtcgaggcgtacacctaccgcatg
ggcgcccacaccacctccgacgacccgacgcgctaccggcgcgacgaggagcggcaggcc
tgggaggccaaggacccgatcctgcgcctgaaggcccacctcctcgcctccggaggcgcc
gacgaggcgttcttcgaggagctggagaccgagagcgaggccctgggcaagcgcgtccgc
gaggtggtgcgcgccatgcccgaccccgacaccatggcgatcttcgagaacgtctacgcg
gacgggcacgcgctcgtcgacgaggagcgcgcccagttcgccgcctacctcgcgtccttc
gaggagggtcactga
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