Streptomyces globosus: C0216_03410
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Entry
C0216_03410 CDS
T06864
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
sgz
Streptomyces globosus
Pathway
sgz00230
Purine metabolism
sgz00670
One carbon pool by folate
sgz01100
Metabolic pathways
sgz01110
Biosynthesis of secondary metabolites
Module
sgz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sgz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
C0216_03410 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
C0216_03410 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
sgz04147
]
C0216_03410 (purH)
Enzymes [BR:
sgz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
C0216_03410 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
C0216_03410 (purH)
Exosome [BR:
sgz04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
C0216_03410 (purH)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
AXE22613
UniProt:
A0A344TVE2
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Position
714577..716154
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AA seq
525 aa
AA seq
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MTAAESTTTSQRPIRRALVSVYDKTGLEELARGLHEAGVALVSTGSTASRIAAAGVPVTK
VEELTGFPECLDGRVKTLHPRVHAGILADLRLEDHRSQLAELGVEPFDLVVVNLYPFRET
VASGATPDECVEQIDIGGPSMVRAAAKNHPSVAVVTSPGRYGDVLAAVRGGGFDLAARKR
LAAEAFQHTAAYDVAVASWFTNAYAPEPEAVLPEFLAGAWDRKAVLRYGENPHQAAALYT
DGQPGGLANAEQLHGKEMSFNNYVDTEAARRAAYDHEEPCVAIIKHANPCGIAIGADIAE
AHRKAHACDPLSAFGGVIAVNRPVTVALAEQIAEIFTEVVAAPAYEDGAVEVLAKKKNIR
VLRVEGSPHQPGDLKPISGGAVLQQSDVFQAEGDDPANWTLATGEALAPAELAELAFAWK
ACRAVKSNAILLAKDGASVGVGMGQVNRVDSARLAVERAGAERAQGSYAASDAFFPFPDG
LEILTAAGVKAVVQPGGSVRDEQVVEAAKAAGVTMYFTGTRHFFH
NT seq
1578 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgccgcagagagcaccacgacgtcgcagcgaccgatccggcgcgcgctcgtcagc
gtctacgacaagacgggactggaggagctggcccgcggcctgcacgaggcgggcgtcgcg
ctcgtctcgaccggctcgaccgcctcccgcatcgccgccgccggcgtccccgtcaccaag
gtggaggagctgaccggcttccccgagtgcctggacgggcgcgtcaagaccctgcacccg
cgcgtgcacgccggcatcctcgccgacctgcgcctggaggaccaccgcagccagctcgcc
gagctgggcgtcgagccgttcgacctggtcgtcgtgaacctctacccgttccgggagacc
gtcgcctccggcgccacccccgacgagtgcgtcgagcagatcgacatcggcggcccgtcc
atggtccgcgcggccgcgaagaaccacccctcggtcgccgtcgtcaccagccccgggcgg
tacggcgacgtcctcgccgcggtccgcggcggcggcttcgacctggccgcccgcaagcgc
ctggccgccgaggccttccagcacacggccgcctacgacgtcgccgtcgcctcctggttc
acgaacgcgtacgcccccgagccggaggccgtgctgcccgagttcctggccggcgcctgg
gaccgcaaggccgtcctgcgctacggcgagaacccgcaccaggccgccgccctgtacacc
gacgggcagccgggcgggctcgccaacgccgagcagctgcacggcaaggagatgtccttc
aacaactacgtggacaccgaggccgcccgccgcgccgcctacgaccacgaagagccgtgc
gtcgcgatcatcaagcacgccaacccgtgcggcatcgcgatcggcgccgacatcgccgag
gcgcaccgcaaggcgcacgcctgcgacccgctgtcggccttcggcggcgtcatcgccgtc
aaccgcccggtgaccgtcgcgctcgccgagcagatcgcggagatcttcaccgaggtcgtc
gccgcccccgcctacgaggacggagcggtcgaggtcctggcgaagaagaagaacatccgc
gtgctgcgcgtcgagggcagcccgcaccagccgggcgacctcaagccgatctcgggcggc
gcggtcctccagcagagcgacgtcttccaggccgagggcgacgacccggcgaactggacc
ctggccaccggcgaggccctcgcccccgccgagctcgccgagctcgcgttcgcgtggaag
gcctgccgggccgtgaagtccaacgcgatcctgctcgccaaggacggcgcctcggtcggc
gtcggcatgggccaggtcaaccgcgtcgactccgcccgcctcgccgtcgagcgggccggc
gccgagcgcgcgcagggctcgtacgccgcgtccgacgcgttcttccccttcccggacggg
ctggagatcctgaccgccgcaggcgtcaaggccgtcgtgcagccgggcggctccgtccgc
gacgagcaggtcgtcgaggccgcgaaggccgccggggtgaccatgtacttcaccggcacc
cggcacttcttccactga
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