Streptomyces globosus: C0216_12625
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Entry
C0216_12625 CDS
T06864
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sgz
Streptomyces globosus
Pathway
sgz00270
Cysteine and methionine metabolism
sgz00480
Glutathione metabolism
sgz01100
Metabolic pathways
sgz01240
Biosynthesis of cofactors
Module
sgz_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
sgz00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
C0216_12625
09106 Metabolism of other amino acids
00480 Glutathione metabolism
C0216_12625
Enzymes [BR:
sgz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
C0216_12625
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
AXE24187
UniProt:
A0A344TZW6
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Position
complement(2819427..2820824)
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AA seq
465 aa
AA seq
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MHQDSTDPSAARPPGGPDPAPSPITEEGAEDLVRGICFKTGPPRVLGAELEWLVVEAERP
GELVPPERLNAAHDAARTLPLRSGFSIEPGGQMELSSAPASSLTECLDGLRADLAAVRSA
LGSMGLGLQGSGCDPRGAVPRLVASPRYDAMESYLDRSGPGGRAMMRASASVQVCVDAGF
EEPGPFGHGRRWRMAHLLGAVFVSAFANSPGSSGRYAGWRCARQGIWGDLDARRTLAPPL
DAEPRAAWAGHALDTEVMCVRSHGGGRSAWAVPRGVTFRDWLRAAAAPDGRGSGGAGDGG
GPAGPAATLRPPTAEDLEYHLTTLFPPVRPRGHLELRMIDAQPGDDGWLVPVAVVHALFD
DPEASETAYRVAKGLADGYGPEAAPRNRLWRSAARFGPADPELRAAAAVCFRAAVEALPR
LGAATYVVDAVGGFADRYVRRGRCPADDRPPGPEAGAAAGTGVAR
NT seq
1398 nt
NT seq
+upstream
nt +downstream
nt
atgcaccaggactcgaccgacccttctgccgcccggccaccgggcggccccgaccctgct
ccctcccccatcacggaagaaggagccgaggacctcgtccgcggcatctgcttcaagacc
ggcccgccccgcgtcctcggcgccgaactcgaatggctcgtcgtggaagccgagcgcccc
ggcgagctcgttccccccgaacggctgaacgccgcgcacgacgcggctcgcaccctcccc
ctgcggtccggcttcagcatcgagcccggcggccagatggagctcagctccgcgccggcc
tcgtcgctcaccgagtgcctcgacggcctgcgggccgacctcgccgccgtccgctcggcg
ctgggctccatggggctgggcctgcagggctcgggctgcgacccgcggggcgccgtgccg
cgcctggtggcaagcccgcgctacgacgccatggagagctacctcgaccgctccggcccc
ggagggcgcgccatgatgcgggcgtccgcttccgtacaggtctgcgtggacgccgggttc
gaggagccgggccccttcgggcacggccggcgctggcggatggcgcatctgctgggcgcg
gtgttcgtgtccgcgttcgccaactcgcccgggtcctcgggccgctacgcgggctggcgg
tgtgcccggcagggcatctggggcgatctggacgcccgccgcacgctcgccccgcccctg
gacgccgagccgcgggcggcgtgggccggccacgctctggacaccgaggtgatgtgcgta
cggtcgcacggcggcgggcgcagtgcgtgggcggtgccccgcggggtgacgttccgcgac
tggctgcgcgccgcggccgccccggacggccggggcagcgggggcgccggcgacggcggt
ggccccgcagggcccgccgcgacgctgcggccgcccaccgcggaggacctggagtaccac
ctgaccacgctgttcccgccggtgcgcccgcgcgggcacctggagctgcggatgatcgac
gcgcagcccggcgacgacggctggctggtgccggtcgcggtggtgcacgccctgttcgac
gatccggaggcctcggagacggcgtaccgggtggcgaaggggctggccgacgggtacggg
ccggaggccgcgccgcgcaaccggctgtggcggtccgcggcccggttcgggccggccgat
ccggagctgcgggccgcggcggcggtgtgcttccgggcagcggtggaggcactgccgcgg
ctcggggcggccacgtacgtggtggacgcggtgggcggtttcgccgaccggtacgtgcgg
cgcgggcgctgtcccgcggacgaccggccgccgggcccggaggcgggcgcggccgccggg
acgggggtggcgcggtga
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