Streptomyces globosus: C0216_23475
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Entry
C0216_23475 CDS
T06864
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sgz
Streptomyces globosus
Pathway
sgz00300
Lysine biosynthesis
sgz00550
Peptidoglycan biosynthesis
sgz01100
Metabolic pathways
sgz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sgz00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
C0216_23475
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
C0216_23475
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
C0216_23475
Enzymes [BR:
sgz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
C0216_23475
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2126
DUF561
Motif
Other DBs
NCBI-ProteinID:
AXE26022
UniProt:
A0A344U551
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All DBs
Position
complement(5292381..5293805)
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AA seq
474 aa
AA seq
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MIALSLAEIADITGGRPHDIPDPLVTVTGPVVIDSRQVEAGSLFAAFAGERVDGHEFAAG
AVAAGAAAVLATRPVGVPAIVVDDVERALGALARAVVQRLGTDVVALTGSAGKTSTKDLI
AQVLQAHAPTVWTPGSLNNEIGLPLTALRATEETRHLVLEMGARGIGHIAYLAGLTPPRI
GVVLNVGTAHIGEFGGREQIAVAKGELVEALPAAADGGIAVLNADDPLVRAMSARTKART
LLFGEADDADVRAADVRMTPAGQPSFTLHTPTGCGEVTLRLYGEHHVSNALAAAAVAHAL
GMSAMETATALSGAGTLSRWRMEVTERADGVTVVNDAYNANPESMRAALRALAAMGGAAR
ANGGRTWAVLGPMAELGDASLAEHDAVGRLAVRLNVSKLVAVGGIEASWLQLGAYNEGSW
GEESVLVSDAQAAVDLLRSELRPGDVVLVKASRSIGLERVAEALLAGEGEVAGR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctttccctcgccgagatcgccgacatcaccggcgggcggccccacgacata
ccggaccccctggtgacggtcaccgggcccgtcgtcatcgactcccgccaggtcgaggcc
ggcagcctgttcgccgcgttcgccggcgagcgcgtcgacgggcacgagttcgccgccggc
gccgtcgccgcaggcgccgcagccgtgctcgccacgcgtcccgtcggcgtgcccgcgatc
gtcgtcgacgacgtcgaaagggccctcggcgcactcgcacgcgccgtcgtccagcgcctc
ggcaccgacgtggtggccctgaccggctccgccggcaagacctccaccaaggacctcatc
gcgcaggtgctccaggcccacgcccccaccgtgtggacgcccggctccctcaacaacgag
atcggcctgccgctcaccgcgctgcgcgccaccgaggagacccggcacctcgtcctggag
atgggcgcccgcggcatcggccacatcgcctacctcgccggcctgaccccgccccgcatc
ggcgtcgtcctgaacgtcggcaccgcccacatcggcgagttcggcggccgcgagcagatc
gccgtcgccaagggcgagctcgtcgaggccctgcccgcggcggccgacggcggcatcgcc
gtcctcaacgccgacgaccccctcgtgcgcgccatgtccgcccgcaccaaggcccgtacg
ctgctcttcggcgaggccgacgacgccgacgtccgggccgccgatgtccggatgacgccg
gccggacagccctccttcacacttcacacacccaccgggtgcggcgaagtgaccttgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgcgctg
ggcatgtccgccatggagaccgccaccgcgctctccggggcgggcacgctgtcccggtgg
cggatggaggtcaccgagcgggcggacggcgtcacggtcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgggccgcactgcgcgcgctggccgcgatgggcggcgccgccagg
gcgaacggggggcgcacgtgggcggtgctcggtcccatggccgagctcggtgacgcctcg
ctggccgagcacgacgcggtgggacggcttgccgtccggctcaacgtgagcaagctcgtc
gcggtcgggggcatcgaagcgtcctggctgcaactgggcgcctacaacgagggttcgtgg
ggtgaggagtcggtgctcgtgtccgacgcgcaggcggcggtcgacctgttgcgcagtgaa
ctgcgcccgggtgacgtcgtgctggtgaaggcttccaggtcgatcgggctggagcgggtg
gcagaggcgctgctggccggcgagggcgaggtcgccggccgatga
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