Staphylococcus haemolyticus JCSC1435: SH0955
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Entry
SH0955 CDS
T00250
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sha
Staphylococcus haemolyticus JCSC1435
Pathway
sha00300
Lysine biosynthesis
sha00550
Peptidoglycan biosynthesis
sha01100
Metabolic pathways
sha01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sha00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SH0955 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SH0955 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SH0955 (murF)
Enzymes [BR:
sha01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SH0955 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
SIS
Motif
Other DBs
NCBI-ProteinID:
BAE04264
UniProt:
Q4L7W1
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Position
956782..958137
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AA seq
451 aa
AA seq
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MIEVTLQQIQEWIPCDIDSQYLRQTIKGVTIDSRAIKTNMLFIPFKGENVDGHCFVSQAL
KDGAGASFYEKGHDIDDNVKGPIIWVDDTLIALQQLAKAYLKHVNPKVIGVTGSNGKTTT
KDMIESVLHTEFKVKKTQGNYNNEIGLPLTILELDLDTEISILEMGMSGFHEIELLSNIA
EPDIAVITNIGESHMQDLGSREGIAKAKSEITIGLKKEGTFIYDGDEPLLEPHVKKIKHA
KCLSVGLKQDNALVCEVEHSENDGIAFSINGNEHYKLPILGIHNMKNAAIAIAIGHELGL
KYETIQHNINHVQLTGMRMERHITDDDITIINDAYNASPTSMKAAIDTLSQMEGRKIIVL
ADSLELGENSRSMHEEVGAYLEGKNIHTLLTYGKDAKYISDIGGQFVDHVEYFIDKQQLT
QYLINNLVANDKVLVKGSRGNKLEEVVNKLI
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atgatagaagttactttacagcaaattcaggaatggataccttgtgatattgattcacaa
tatttacgacaaaccatcaaaggtgtgacgatcgattcacgtgcaatcaaaactaatatg
ttatttataccatttaaaggtgagaacgtagatggtcattgctttgtttcacaggcgtta
aaagatggcgctggggcttctttctatgaaaagggccatgacattgatgataacgtgaag
ggacctattatatgggtagacgatacattaattgcgttacaacaattagctaaagcatat
cttaaacatgtgaaccctaaagtaataggtgttactggttcaaacggtaaaacaactaca
aaagatatgattgagagtgtattacacactgaatttaaagtaaaaaaaacgcaaggtaat
tacaataatgaaataggcttaccgttaactattttagagcttgatttagatacagagatt
tcaatattagaaatgggtatgtctggattccatgaaatagaattactttctaatatagca
gaaccagatattgctgttattactaatattggtgaatcacatatgcaagatttaggttct
cgtgaaggcattgctaaagctaaatctgaaataacaattggacttaaaaaagaaggaaca
ttcatctatgatggtgatgaaccattgcttgaaccacatgttaaaaaaatcaaacacgct
aaatgtttaagtgtaggtttgaaacaagataatgctttagtatgcgaagtagaacatagt
gaaaatgatggcattgctttctctattaacggtaatgaacattataaattacctattcta
ggaatccataatatgaaaaatgcagctatcgctattgctattggtcatgaactaggactt
aaatatgagactattcaacataacattaatcatgttcaacttactggtatgcgaatggaa
cgccatattactgatgatgatattactatcataaatgatgcttataatgccagtcctaca
agtatgaaagccgcaattgatactttgagtcaaatggaaggtagaaaaattattgtactt
gctgactcacttgaattaggggaaaatagtcgttcaatgcacgaagaggtaggcgcatat
ttagaaggtaaaaacatccatacattattaacatatggcaaagatgcaaagtatattagt
gatattggaggacaatttgttgaccacgttgaatattttattgataaacaacaattaact
caatatttaataaataacttagttgctaacgacaaagttcttgtaaaaggttcaagagga
aataaacttgaagaagttgtaaataaattgatttaa
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