Streptomyces harbinensis: HUT13_10290
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Entry
HUT13_10290 CDS
T07389
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
shar
Streptomyces harbinensis
Pathway
shar00790
Folate biosynthesis
shar01100
Metabolic pathways
shar01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
shar00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HUT13_10290
Enzymes [BR:
shar01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HUT13_10290
6.3.2.17 tetrahydrofolate synthase
HUT13_10290
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QKV69129
UniProt:
A0A7H8GZE4
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Position
complement(2316773..2318365)
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AA seq
530 aa
AA seq
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MTEHSRPEPPDSGDSGEAGTPGDFDAAAFEELIGAETQRDPDLAVIEAGSRTLRTQAGPP
AGDGVPDRPADPEVDRALREVETELSKRWGETKLDPSVTRIKALMDVLGEPQRAYPAIHI
TGTNGKTSTARMIEALLGGFELRTGRYSSPHVQSITERISLDGAPLPAERFVAAYEDVKP
YVELVDAREEYRLSFFEVLTAMAYSAFADAPVDVAVVEVGMGGTWDATNVLDAGVAVITP
ISLDHTDRLGGTPAEIAAEKSGIVKQDATVVLAQQPIEAASVILRRAVEVDATVAREGME
FGVVSREIAVGGQLLTLRGLGGEYPDIFLPLHGEHMAHNAVVALAAVEAFFGIGATQASR
TLDIEVVRAAFAAVTSPGRLEVIRSSPTVLLDAAHNPGGAQAAAAAVSEAFGFSRLIGVV
GPSADKDVTGVLEAFEPIFTEIVVTRNSSHRAMDVDQLAAAAVEVFGEDRVQVEPRLDDA
LEAAISLAEAEDEYAGAGVLITGSVITVGEARMLLRGPGRRGGGREAGDR
NT seq
1593 nt
NT seq
+upstream
nt +downstream
nt
gtgactgagcactcccgccccgagccccccgattccggcgattccggcgaggccggcacc
cccggcgacttcgacgccgcggccttcgaggagctgatcggtgccgagacccagcgggac
ccggatctcgcggtgatcgaggccggcagccgcacgctgcgcacccaggcgggcccgccc
gccggggacggcgtgccggaccgcccggctgacccggaggtggaccgggcgctgcgcgag
gtcgagacggagctgtccaagcgctggggcgagacgaagctcgacccgtccgtcacccgg
atcaaggccctgatggacgtgctcggcgagccccagcgcgcctacccggcgatccacatc
accggcaccaacgggaagaccagcaccgcccggatgatcgaggcgctgctcggcggcttc
gagctgcgcaccggccggtacagcagcccgcatgtgcagtccatcaccgagcggatcagc
ctggacggcgcgccgctgcccgccgagcggttcgtcgccgcgtacgaggacgtcaagccg
tacgtggagctggtggacgcccgggaggagtaccgcctctcgttcttcgaggtgctcacc
gcgatggcctactcggccttcgccgacgccccggtggacgtggccgtggtcgaggtcggg
atgggcggcacctgggacgccaccaatgtgctggacgccggggtggcggtgatcaccccg
atcagcctggaccacaccgaccggctgggcggcacgcccgccgagatcgccgccgagaag
tccggcatcgtcaagcaggacgccacggtggtgctggcccagcagccgatcgaggccgcc
tcggtgatcctgcgccgcgccgtcgaggtggacgccacggtggcccgggagggcatggag
ttcggcgtggtgtcccgggagatcgcggtcggcgggcagttgctgacgctgcgcggcctc
ggcggtgagtaccccgacatcttccttccgctgcacggcgagcacatggcgcacaacgcg
gtggtggcgctcgcggcggtggaggcgttcttcggcatcggcgccacccaggcctcgcgc
accctggacatcgaggtggtgcgggccgcgttcgccgccgtcacctcgccggggcgtctc
gaggtgatccgctccagccccacggtgctgctggacgccgcgcacaacccgggcggcgcg
caggcggcagccgccgccgtctccgaggcgttcggcttcagccggctcatcggggtggtc
ggccccagcgccgacaaggacgtcaccggggtgctggaggccttcgagccgatcttcacc
gagatcgtggtcacccggaactccagccaccgcgccatggacgtggaccagctcgccgcg
gcggccgtcgaggtcttcggcgaggaccgggtgcaggtcgagccgcggctggacgacgcg
ctggaggcggcgatctcgctggccgaggcggaggacgagtacgccggcgccggggtgctg
atcaccggctccgtcatcacggtcggcgaggcgcgcatgctgctgcgcggcccgggccgg
cgcggcggcggccgggaagcgggggaccgctga
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