Streptomyces hawaiiensis: CEB94_29085
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Entry
CEB94_29085 CDS
T06917
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
shaw
Streptomyces hawaiiensis
Pathway
shaw00290
Valine, leucine and isoleucine biosynthesis
shaw00660
C5-Branched dibasic acid metabolism
shaw01100
Metabolic pathways
shaw01110
Biosynthesis of secondary metabolites
shaw01210
2-Oxocarboxylic acid metabolism
shaw01230
Biosynthesis of amino acids
Module
shaw_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
shaw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CEB94_29085 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CEB94_29085 (leuC)
Enzymes [BR:
shaw01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CEB94_29085 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CEB94_29085 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
QCD58448
UniProt:
A0A6G5RJW6
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Position
6189325..6190755
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRGVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNAADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMSRPKTMAITVDGELPEGVTA
KDLILAIIAKIGTGGGQGYVLEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
DYLKGRPHAPEGEDWDAAVAYWKTLRTDEDAEFDAEVVIDASGLSPFVTWGTNPGQGAPL
SASVPDPASYEDASERYAAEKALEYMGLEAGQPLRSIKVDTVFVGSCTNGRIEDLRAAAE
LIKDRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSAADAPTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaagtctgggacgaccatgtcgtccggcgcgcggagggc
gagcccgaccttctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctccgcaagagcggccgcggcgtgcggcgtctggacctcaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagccgatcgcggatccggtctcccgg
gtgcagctggagacgctgcgcaagaacgccgccgacttcggtgtgcgtctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtcgtcggcccgcagctgggcctgacccagccc
ggcatgaccgtggtctgcggcgactcccacacctccacgcacggcgccttcggcgcgctg
gcgttcggcatcggcacctcccaggtggaacacgtgctggccacccagacgctgccgatg
tcccgcccgaagaccatggcgatcacggtcgacggtgaactgcccgagggcgtcaccgcc
aaggacctgatcctggcgatcatcgcgaagatcggcacgggcggcggccagggctacgtc
ctggagtaccgcggcgaggccatcgagaagctctcgatggaagcccgcatgaccatctgc
aacatgtcgatcgaagccggcgcccgcgcgggcatgatcgccccggacgagaccaccttc
gactacctcaagggccgcccgcacgcccccgagggcgaggactgggacgcggccgtcgcg
tactggaagacgctcaggacggacgaggacgccgagttcgacgccgaggtcgtcatcgac
gcctccggactgtcgccgttcgtcacctggggtaccaacccgggccagggcgcaccgctt
tcggcgtccgtccccgatcccgcttcgtacgaagacgcatcggagcgctacgccgcggaa
aaggccctggagtacatggggttggaggccgggcagccgctgcgctccatcaaggtggac
accgtcttcgtaggctcgtgcaccaacggccgcatcgaggacctgcgcgccgccgccgag
ctgatcaaggaccgcaaagtcgccgacggcgtacggatgctggtcgtcccgggctccgcg
cgcgtcggtctgcaggccgtttccgaggggctggacgtcgtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctggccccg
ggtgagcgctccgcgtccacctccaaccgcaacttcgagggccggcagggcaagggcggc
cgcacccacctggtgtctccgcaggtcgccgccgccaccgccgtcctgggccacctggcc
tccccggccgacctgtccgccgccgacgcccccacgcccgctggagtctga
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